المؤلفون: Fabian Model, Ludwig Kappos, Stephen L. Hauser, Heidemarie Kletzl, Ekaterina Gibiansky, Andreas Günther, Claire Petry, Ann Herman, Francois Mercier, Yumi Yamamoto, Qing Wang

المصدر: British Journal of Clinical Pharmacology
British journal of clinical pharmacology, vol 87, iss 6

مصطلحات موضوعية: Phases of clinical research, Relapsing-Remitting, Neurodegenerative, 030226 pharmacology & pharmacy, Gastroenterology, 0302 clinical medicine, population analysis, Monoclonal, Medicine, Pharmacology (medical), 030212 general & internal medicine, Pharmacology & Pharmacy, Humanized, education.field_of_study, Pharmacology and Pharmaceutical Sciences, Multiple Sclerosis, Chronic Progressive, Chronic Progressive, Original Article, medicine.drug, medicine.medical_specialty, Multiple Sclerosis, pharmacokinetic-pharmacodynamic, Population, Primary Progressive Multiple Sclerosis, Antibodies, Monoclonal, Humanized, Autoimmune Disease, Antibodies, 03 medical and health sciences, Multiple Sclerosis, Relapsing-Remitting, Pharmacokinetics, Internal medicine, pharmacokinetic–pharmacodynamic, pharmacodynamics, Humans, Immunologic Factors, In patient, education, Pharmacology, business.industry, Multiple sclerosis, neurology, pharmacokinetic–, Neurosciences, Original Articles, medicine.disease, Brain Disorders, pharmacodynamic, Pharmacodynamics, Ocrelizumab, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8811580eb5543d689634ed86d7b68a05Test
http://europepmc.org/articles/PMC8247316Test

المؤلفون: Yumi Cleary, Katja Heinig, Lutz Müller, Hasane Ratni, Omar Khwaja, Nicolas Frances, Paul Jordan, Agnès Poirier, Birgit Jaber, Tobias Bergauer, Heidemarie Kletzl, Nada Al Kotbi, Stefan Sturm, Anne Marquet, Andreas Günther, Christian Czech, Nikhat Parkar

المصدر: British journal of clinical pharmacology. 85(1)

مصطلحات موضوعية: Adult, Male, Adolescent, CYP3A, Itraconazole, RNA Splicing, Administration, Oral, Pharmacology, Placebo, 030226 pharmacology & pharmacy, Muscular Atrophy, Spinal, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Pharmacokinetics, Double-Blind Method, Medicine, Humans, Pharmacology (medical), Drug Interactions, 030212 general & internal medicine, RNA, Messenger, Volunteer, business.industry, Original Articles, Middle Aged, Confidence interval, Healthy Volunteers, Survival of Motor Neuron 2 Protein, Pyrimidines, Tolerability, Neuromuscular Agents, Pharmacodynamics, Area Under Curve, Cytochrome P-450 CYP3A Inhibitors, business, Azo Compounds, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39a179691a66077906bc034e6725650dTest
https://pubmed.ncbi.nlm.nih.gov/30302786Test

المؤلفون: Norcross Roger, Moshe Finel, Nenad Manevski, Victor A. Iglesias, Marius C. Hoener, Dietrich Tuerck, Stephen Fowler, Paul Schmid, Olivia Spleiss, Heidemarie Kletzl

المصدر: Journal of Pharmacology and Experimental Therapeutics. 352:358-367

مصطلحات موضوعية: UGT1A4, Glucuronidation, Black People, Pharmacology, Biology, Polymorphism, Single Nucleotide, 030226 pharmacology & pharmacy, DNA sequencing, Substrate Specificity, law.invention, 03 medical and health sciences, Glucuronides, 0302 clinical medicine, Tandem Mass Spectrometry, law, Humans, Gene Silencing, Glucuronosyltransferase, Oxazoles, Cells, Cultured, Chromatography, High Pressure Liquid, 030304 developmental biology, Genetics, chemistry.chemical_classification, 0303 health sciences, Splice site mutation, 3. Good health, Enzyme, chemistry, Drug development, RNA splicing, Microsomes, Liver, Recombinant DNA, Molecular Medicine, Databases, Nucleic Acid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8172f13f9cad04a04e634c848f42a827Test
https://doi.org/10.1124/jpet.114.220194Test

المؤلفون: Miriam Pein-Hackelbusch, Heidemarie Kletzl, Stefan Sturm, Peter Kühl, Laura Isabell Immohr, Andreas Günther, Angela Dischinger

المصدر: International journal of pharmaceutics. 530(1-2)

مصطلحات موضوعية: Adult, Male, Taste, Electronic tongue, Chemistry, Pharmaceutical, Pharmaceutical Science, 02 engineering and technology, Pharmacology, Oral cavity, 030226 pharmacology & pharmacy, Excipients, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Tongue, Medicine, Humans, Palatability, Electronic Nose, business.industry, Healthy subjects, 021001 nanoscience & nanotechnology, Pediatric drug, medicine.anatomical_structure, 0210 nano-technology, business, Oral retinoid, Cognitive psychology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9595a91512e275eeb1872b2a5679567Test
https://pubmed.ncbi.nlm.nih.gov/28750893Test