المؤلفون: Ruth M Barnard, David Inman, Kevin R. Page, Bart Keymeulen, Quentin Leirens, Alexander MacDonald, Antonella Napolitano, Kim Brown, David Lanham, Jonathan Bullman, Minesh Patel, André van Maurik, Enrica Mezzalana, Caroline O. S. Savage, Georgios Vlasakakis, Stefano Zamuner

المساهمون: Pathology/molecular and cellular medicine, Diabetes Pathology & Therapy, Diabetes Clinic

المصدر: British Journal of Clinical Pharmacology. 85:704-714

مصطلحات موضوعية: Adult, Male, Adolescent, CD3 Complex, type 1 diabetes, T-Lymphocytes, Receptors, Antigen, T-Cell, Pharmacology, Antibodies, Monoclonal, Humanized, 030226 pharmacology & pharmacy, Otelixizumab, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, medicine, immunoinflammation, Humans, Pharmacology (medical), Molecular Targeted Therapy, 030212 general & internal medicine, Dosing, Infusions, Intravenous, PK/PD models, Type 1 diabetes, Dose-Response Relationship, Drug, target engagement, business.industry, T-cell receptor, PK/PD, Original Articles, medicine.disease, Clinical trial, Diabetes Mellitus, Type 1, Treatment Outcome, Pharmacodynamics, Female, dose–response, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b3cc8aff306a4ae44c500abe35002d5Test
https://doi.org/10.1111/bcp.13842Test

المؤلفون: Simon M. McHugh, Paul W. Thompson, Frank A Gray, Onajite Kousin-Ezewu, Jenny L Craigen, Disala Fernando, Alasdair Coles, Donggang Su, Joanne Ellis, Keguan Chen, Sara Santos Franco, Joao-Joaquim Oliveira, Kim Brown, Lea Fortunato, André van Maurik, Ann M. Schwartz, Sophie Gisbert, Jiansong Yang, Sara Brett, Bill Davis, Joseph Cheriyan, Andrew Want, Jeffrey Price

المصدر: British Journal of Clinical Pharmacology

مصطلحات موضوعية: Adult, Male, drug safety, Adolescent, medicine.medical_treatment, T cell, T-Lymphocytes, Pharmacology, Antibodies, Monoclonal, Humanized, 030226 pharmacology & pharmacy, Autoimmune Diseases, immunology, Interleukin-7 Receptor alpha Subunit, Placebos, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Pharmacokinetics, Double-Blind Method, medicine, pharmacodynamics, Humans, Pharmacology (medical), 030212 general & internal medicine, Interleukin-7 receptor, Receptor, Infusions, Intravenous, Aged, biology, business.industry, Interleukin, Original Articles, Middle Aged, Healthy Volunteers, Cytokine, medicine.anatomical_structure, Pharmacodynamics, biology.protein, Original Article, Female, monoclonal antibodies, Antibody, business, pharmacokinetics, Half-Life

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af326e175e6773cbef32639a120f87e8Test
http://europepmc.org/articles/PMC6339973Test