نتائج البحث - "Rinath Jeselsohn"

1

Activation of the IFN Signaling Pathway is Associated with Resistance to CDK4/6 Inhibitors and Immune Checkpoint Activation in ER-Positive Breast Cancer

المساهمون: De Angelis, C., Fu, X., Cataldo, M. L., Nardone, A., Pereira, R., Veeraraghavan, J., Nanda, S., Qin, L., Sethunath, V., Wang, T., Hilsenbeck, S. G., Benelli, M., Migliaccio, I., Guarducci, C., Malorni, L., Litchfield, L. M., Liu, J., Donaldson, J., Selenica, P., Brown, D. N., Weigelt, B., Reis-Filho, J. S., Park, B. H., Hurvitz, S. A., Slamon, D. J., Rimawi, M. F., Jansen, V. M., Jeselsohn, R., Osborne, C. K., Schiff, R.

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research, vol 27, iss 17

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Pyridines, Oncology and Carcinogenesis, Estrogen receptor, Antineoplastic Agents, Breast Neoplasms, Palbociclib, Piperazines, 03 medical and health sciences, 0302 clinical medicine, Immune system, Breast cancer, Receptors, Breast Cancer, Genetics, Tumor Cells, Cultured, Humans, Medicine, Oncology & Carcinogenesis, Cancer, Cultured, biology, business.industry, Kinase, Cyclin-Dependent Kinase 4, Cyclin-Dependent Kinase 6, medicine.disease, Estrogen, Immune checkpoint, Tumor Cells, Good Health and Well Being, 030104 developmental biology, Receptors, Estrogen, Oncology, 5.1 Pharmaceuticals, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Female, Cyclin-dependent kinase 6, Development of treatments and therapeutic interventions, Signal transduction, business, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8d5dea84c01cc54303c5f5ebf7c4dcTest
https://doi.org/10.1158/1078-0432.ccr-19-4191Test

2

The Dysregulated Pharmacology of Clinically Relevant ESR1 Mutants is Normalized by Ligand-activated WT Receptor

المؤلفون: Rachid Safi, Suzanne E. Wardell, Kaitlyn Andreano, Steffi Oesterreich, Ching-Yi Chang, Donald P. McDonnell, Sunghee Park, Myles Brown, Sarah Sammons, Sandeep Artham, John D. Norris, Jennifer G. Baker, Rinath Jeselsohn

المصدر: Molecular Cancer Therapeutics. 19:1395-1405

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::8c70e648999333673bd4e6986eab1ff9Test
https://doi.org/10.1158/1535-7163.mct-19-1148Test

3

Impact of a Pre-Operative Exercise Intervention on Breast Cancer Proliferation and Gene Expression: Results from the Pre-Operative Health and Body (PreHAB) Study

المصدر: Clinical Cancer Research. 25:5398-5406

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de4492eeeec844076ba8f316a34df88Test
https://doi.org/10.1158/1078-0432.ccr-18-3143Test

4

Abstract PD7-12: Inhibition of CDK7 overcomes resistance to CDK4/6 inhibitors in hormone receptor positive breast cancer cells

المؤلفون: Myles Brown, Antonio Nardone, A. Di Leo, Luca Malorni, C. Guarducci, Rinath Jeselsohn, I. Migliaccio, Geoffrey I. Shapiro, Martina Bonechi, A Feiglin, M. Benelli, G Hodgson

المصدر: Cancer Research. 79:PD7-12

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::83ed4d202ffa416c74009cddb10ca97fTest
https://doi.org/10.1158/1538-7445.sabcs18-pd7-12Test

5

The oral selective oestrogen receptor degrader (SERD) AZD9496 is comparable to fulvestrant in antagonising ER and circumventing endocrine resistance

المؤلفون: Agostina Nardone, Rachel Schiff, Henry Brown, Meghana V. Trivedi, Martin Shea, Mark Pilling, Jamunarani Veeraraghavan, Chandandeep Nagi, Rinath Jeselsohn, Carmine De Angelis, Oona Delpuech, Maria Letizia Cataldo, Tamika Mitchell, C. Kent Osborne, Mothaffar F. Rimawi, Hazel M. Weir, Gary C. Chamness, Xiaoyong Fu, Susan G. Hilsenbeck

المساهمون: Pilling, Mark [0000-0002-7446-6597], Apollo - University of Cambridge Repository, Nardone, A., Weir, H., Delpuech, O., Brown, H., De Angelis, C., Cataldo, M. L., Fu, X., Shea, M. J., Mitchell, T., Veeraraghavan, J., Nagi, C., Pilling, M., Rimawi, M. F., Trivedi, M., Hilsenbeck, S. G., Chamness, G. C., Jeselsohn, R., Osborne, C. K., Schiff, R.

المصدر: British Journal of Cancer

مصطلحات موضوعية: Cancer Research, Indoles, Neoplasms, Hormone-Dependent, Breast Neoplasms, Article, 03 medical and health sciences, chemistry.chemical_compound, Mice, MCF-7 Cell, 0302 clinical medicine, Breast cancer, Cinnamate, In vivo, medicine, Animals, Humans, Receptor, skin and connective tissue diseases, Fulvestrant, Cancer, Cell Proliferation, Estradiol, Animal, Cell growth, Estrogens, medicine.disease, Estrogen, Metastatic breast cancer, 3. Good health, Tamoxifen, Oncology, chemistry, Receptors, Estrogen, Indole, Cell culture, Cinnamates, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Cancer research, MCF-7 Cells, Heterografts, Female, Growth inhibition, Heterograft, Breast Neoplasm, Human, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1307add3c66d5075ec69b579adb4aedTest
http://europepmc.org/articles/PMC6353941Test

6

An embryonic diapause-like adaptation with suppressed Myc activity enables tumor treatment persistence

المصدر: Cancer Cell

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27960f6b5655eb355223383013aae78cTest
https://europepmc.org/articles/PMC8670073Test/

7

The ESR1 Mutations: From Bedside to Bench to Bedside

المؤلفون: Francisco Hermida-Prado, Rinath Jeselsohn

المصدر: Cancer Research. 81:537-538

مصطلحات موضوعية: 0301 basic medicine, Genetics, Cancer Research, biology, Mechanism (biology), Estrogen receptor, Bench to bedside, body regions, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Acquired resistance, Oncology, 030220 oncology & carcinogenesis, biology.protein, CRISPR, Aromatase, Estrogen receptor alpha

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::ba0961167ad0e8d28c2eb2d27a0a7c9dTest
https://doi.org/10.1158/0008-5472.can-20-4037Test

8

Increased lysosomal biomass is responsible for the resistance of triple-negative breast cancers to CDK4/6 inhibition

المساهمون: Fassl, A., Brain, C., Abu-Remaileh, M., Stukan, I., Butter, D., Stepien, P., Feit, A. S., Bergholz, J., Michowski, W., Otto, T., Sheng, Q., Loo, A., Michael, W., Tiedt, R., De Angelis, C., Schiff, R., Jiang, B., Jovanovic, B., Nowak, K., Ericsson, M., Cameron, M., Gray, N., Dillon, D., Zhao, J. J., Sabatini, D. M., Jeselsohn, R., Brown, M., Polyak, K., Sicinski, P.

المصدر: Science Advances

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc4815f131efc64eea3d77fec1fe579fTest
http://hdl.handle.net/11588/857297Test

9

Are We Ready to Use ESR1 Mutations in Clinical Practice

المؤلفون: Rinath Jeselsohn

المصدر: Breast Care. 12:309-313

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c30b1b324f668483a8057a0dace9f7dTest
https://doi.org/10.1159/000481428Test

10

A phase II feasibility study of palbociclib in combination with adjuvant endocrine therapy for hormone receptor-positive invasive breast carcinoma

المؤلفون: Maria Koehler, Angela DeMichele, William T. Barry, Rinath Jeselsohn, Beth Overmoyer, EP Winer, Adrienne G. Waks, Kathy D. Miller, Harold J. Burstein, Hope S. Rugo, C Huang Bartlett, Therese M. Mulvey, H Guo, Erica L. Mayer, Steven E. Come

المصدر: Annals of oncology : official journal of the European Society for Medical Oncology. 30(9)

مصطلحات موضوعية: 0301 basic medicine, Oncology, Adult, medicine.medical_specialty, Pyridines, Receptor, ErbB-2, Population, Breast Neoplasms, Palbociclib, Disease-Free Survival, Piperazines, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Cumulative incidence, Neoplasm Invasiveness, education, Fulvestrant, Protein Kinase Inhibitors, Neoplasm Staging, education.field_of_study, Estradiol, business.industry, Hematology, Middle Aged, medicine.disease, Metastatic breast cancer, Discontinuation, 030104 developmental biology, Tolerability, Receptors, Estrogen, Chemotherapy, Adjuvant, 030220 oncology & carcinogenesis, Feasibility Studies, Female, business, Receptors, Progesterone, Febrile neutropenia

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d92854b34d679e7f53cb104cae812975Test
https://pubmed.ncbi.nlm.nih.gov/31250880Test

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