نتائج البحث - "NHEJ, non-homologous end-joining"

المصدر: Neoplasia (New York, N.Y.)
BASE-Bielefeld Academic Search Engine
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 1, Pp 80-98 (2021)
Neoplasia (United States), 23(1), 80-98

مصطلحات موضوعية: Apoptosis, FOXO3a, forkheadbox protein O3a, d, day(s), Rb, retinoblastoma protein, Mice, 0302 clinical medicine, JC-1, 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazolcarbocyanine iodide, Molecular Targeted Therapy, BER, base excision repair, Bortezomib, IC50, dose of half-maximum inhibitory effect, Ga-68, Gallium-68, Drug Synergism, DSMZ, Deutsche Sammlung für Mikroorganismen und Zellen, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Immunohistochemistry, Neuroendocrine Tumors, G0/1/2 phase, gap phase 0/1/2, 030220 oncology & carcinogenesis, CAM, chorioallantoic membrane, (M)Bq, (Mega-)Becquerel, Original article, PRRT, peptide receptor radionuclide therapy, DNA damage, p70S6K, ribosomal protein S6 kinase, DNA repair, Antineoplastic Agents, NEN, neuroendocrine neoplasms, ERK, extracellular-signal-regulated kinase, lcsh:RC254-282, AP-sides, apurinic or apyrimidinic sites, M phase, mitosis phase, 03 medical and health sciences, SDG 3 - Good Health and Well-being, In vivo, i.v., intravenous, NER, nucleotide excision repair, GO, Gene Ontology, Humans, Combination therapy, FOXM1, forkheadbox protein M1, Cisplatin, G1/2/3, grade 1/2/3, Dose-Response Relationship, Drug, Proteasome inhibition, Cell Cycle Checkpoints, n, number, H2AX, histone H2AX, 030104 developmental biology, Proteasome, NHEJ, non-homologous end joining, g, gram, Proteasome inhibitor, HR, homologous recombination, 0301 basic medicine, Cancer Research, BRIP1, BRCA1 Interacting Protein C-Terminal Helicase 1, Chick Embryo, RPA, replication protein A, GEP-NEN, gastroenteropancreatic neuroendocrine neoplasms, SCLC, small cell lung cancer, Gene Regulatory Networks, TGF, transforming growth factor, HTCA, human tumor colony assay, Gastrointestinal Neoplasms, i.p., intraperitoneal, M, molar, Lu-177, Lutetium-177, Proteasome Inhibitors, F-18-FDG-PET, 2-deoxy-2-(F-18)fluoro-D-glucose positron emission tomography, SSTR2, somatostatin receptor 2, PI3K, phosphoinositide 3-kinase, medicine.drug, DDR, DNA damage repair, MMR, mismatch repair, SKP2, S-Phase Kinase Associated Protein 2, PARP1, poly(ADP-ribose) polymerase 1, (RT)-PCR, (real-time) polymerase chain reaction, BRCA1/2, breast cancer protein 1/2, ER, endoplasmic reticulum, ROS, reactive oxygen species, S phase, synthesis phase, Cell Line, Tumor, h, hour(s), medicine, Animals, TLS, translesion synthesis, Cell Proliferation, business.industry, DSB, double-strand breaks, PTEN, phosphatase and tensin homolog, CK2, casein kinase 2, Drug Resistance, Neoplasm, Radionuclide therapy, SSB, single-strand breaks, Cancer research, business, MRI, magnetic resonance imaging, DNA Damage, Peptide receptor radionuclide therapy (PRRT)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b0fcaaba5da9ca61e63d327232b0b4Test
http://www.scopus.com/inward/record.url?scp=85096683387&partnerID=8YFLogxKTest

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Efficient

المؤلفون: Leszek Lisowski, Sophia H.Y. Liao, Szun S. Tay, Ian E. Alexander, Grant J Logan, Samantha L. Ginn, Claus V. Hallwirth, Markus Grompe, Anais K. Amaya, Erhua Zhu, Hilda A. Pickett, Kimberley L. Dilworth, Anthony J. Cesare, Sharon C. Cunningham, Michael Lee

المصدر: JHEP Reports, Vol 2, Iss 1, Pp-(2020)
JHEP Reports

مصطلحات موضوعية: Genetic enhancement, ITR, inverted terminal repeats, medicine.disease_cause, RTA, Real Time Analysis, BrdU, bromodeoxyuridine, AAV, adeno-associated virus, 0302 clinical medicine, Genome editing, 7 NGS, next-generation sequencing, recombinant AAV, Immunology and Allergy, CRISPR, Adeno-associated virus, HDR, homology-directed repair, 0303 health sciences, NP59 capsid, Gastroenterology, humanised FRG mice, rAAV, recombinant adeno-associated virus, 3. Good health, homology-directed repair, U6, RNA polymerase III promoter for human U6 snRNA, 030220 oncology & carcinogenesis, SaCas9, Staphylococcus aureus Cas9 nuclease, CRISPR-Cas9, Research Article, TBG, human thyroxine binding globulin promoter, Ornithine transcarbamylase, Computational biology, Biology, LSP1, liver-specific promoter, Homology directed repair, 03 medical and health sciences, synthetic capsid, PRE, mutant form of the Woodchuck hepatitis virus posttranscriptional regulatory element, InDels, insertions and deletions, PAM, protospacer adjacent motif, Internal Medicine, medicine, genome editing, lcsh:RC799-869, Gene, 030304 developmental biology, Hepatology, OTC deficiency, sgRNA, single guide RNA, WT, wild-type, FRG, Fah-/-Rag2-/-Il2rg, primary human hepatocytes, NHEJ, non-homologous end joining, lcsh:Diseases of the digestive system. Gastroenterology, pA, bovine growth hormone polyadenylation signal sequence, SV40 pA, SV40 polyadenylation signal sequence, Minigene

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db43f1b07a8924ee43c66eaf654d9a6bTest
https://pubmed.ncbi.nlm.nih.gov/32039406Test

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The roles of the human SETMAR (Metnase) protein in illegitimate DNA recombination and non-homologous end joining repair

المؤلفون: Ronald Chalmers, Michael Tellier

المصدر: DNA Repair

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb42ee4bfe72e379a40f8def4c08a3cTest
http://ora.ox.ac.uk/objects/uuidTest:

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APC loss affects DNA damage repair causing doxorubicin resistance in breast cancer cells

المؤلفون: Lauren Milac, Casey D. Stefanski, Kaitlyn Keffler, Jenifer R. Prosperi, Stephanie McClintock

المصدر: Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 12, Pp 1143-1150 (2019)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, DNA Repair, ER, estrogen receptor, DNA Repair Inhibition, medicine.medical_treatment, Apoptosis, Chk2, checkpoint kinase 2, Targeted therapy, PyMT, polyoma middle T antigen, Mice, 0302 clinical medicine, Medicine, HER2, human epidermal growth factor, Triple-negative breast cancer, SSBs, single stranded breaks, TNBC, triple negative breast cancer, Mammary tumor, ATM, ataxia telangiectasia mutated, biology, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Chk1, checkpoint kinase 1, 3. Good health, 030220 oncology & carcinogenesis, Female, medicine.drug, Signal Transduction, Original article, Genes, APC, DNA damage, Adenomatous polyposis coli, DNA repair, CC3, cleaved caspase 3, DSBs, double stranded breaks, Breast Neoplasms, lcsh:RC254-282, Etop, etoposide, Topo IIα, topoisomerase IIα, 03 medical and health sciences, DNA-PK, DNA-dependent protein kinase, Cell Line, Tumor, Animals, Humans, STAT3, activation of signal transducer and activation of transcription 3, Doxorubicin, APC, Adenomatous Polyposis Coli, Cell Proliferation, business.industry, CIS, cisplatin, PR, progesterone receptor, DOX, doxorubicin, PTX, paclitaxel, 030104 developmental biology, Drug Resistance, Neoplasm, NHEJ, non-homologous end joining, Cancer research, biology.protein, ATR, ataxia telangiectasia and Rad3 related, H2AX, histone 2AX, business, HRR, homologous recombination repair, Gene Deletion, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369502e33e9032d8e43fcc56f9429f59Test
https://pubmed.ncbi.nlm.nih.gov/31759252Test

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Role of nitric oxide in the radiation-induced bystander effect

المؤلفون: Vasily A. Yakovlev

المصدر: Redox Biology

مصطلحات موضوعية: Genome instability, Cav-1, caveolin 1 protein, Clinical Biochemistry, BRCA1, breast cancer type 1 susceptibility protein, Biochemistry, Direct DNA damage, chemistry.chemical_compound, SSF, stress signal factor, 0302 clinical medicine, PP2A, protein phosphatase 2A, Bystander effect, cNOS, constitutive nitric oxide synthase, NOS, nitric oxide synthase, 0303 health sciences, cGy, centigray, eNOS, endothelial nitric oxide synthase, Reactive nitrogen species, Neoplasm Proteins, Cell biology, NHEJ, non-homologous end-joining, Cell Transformation, Neoplastic, Eukaryotic Cells, GI, genomic instability, 030220 oncology & carcinogenesis, Homologous recombination repair, iNOS, inducible nitric oxide synthase, Signal transduction, Signal Transduction, Research Paper, GJIC, gap junction intercellular communication, Genomic instability, DNA damage, Non-homologous end-joining, c-PTIO, 2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide, E2F4, transcription factor E2F4, Biology, Nitric Oxide, RNS, reactive nitrogen species, 03 medical and health sciences, l-NAME, L-NG-nitroarginine methyl ester, Humans, DSB, double-strand break, Cysteine, MN, micronuclei, 030304 developmental biology, NO, nitric oxide, Gap junction intercellular communication, Organic Chemistry, Mutagenesis, RIBE, radiation-induced bystander effect, Bystander Effect, BRCA1, Molecular biology, RBL2, retinoblastoma-like protein 2, chemistry, Gamma Rays, DNA double-strand break, Radiation-induced bystander effect, Tyrosine, HRR, homologous recombination repair, Homologous recombination, Protein Processing, Post-Translational, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f22d39f57664390fa46ffa89e1be29f0Test

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An inherited immunoglobulin class-switch recombination deficiency associated with a defect in the INO80 chromatin remodeling complex

المؤلفون: Jacek Majewski, Nada Jabado, Marina Cavazzana, Alain Fischer, Jeremy Schwartzentruber, Anne Durandy, Monique Forveille, Michel C. Nussenzweig, Sven Kracker, Necil Kutukculer, Cyrille Cuenin, Anna Gazumyan, Kevin M. McBride, Suranjith L. Seneviratne, Michela Di Virgilio, Zdenko Herceg, Bodo Grimbacher, Marie Céline Deau

المساهمون: Ege Üniversitesi

المصدر: Journal of Allergy and Clinical Immunology
The Journal of Allergy and Clinical Immunology

مصطلحات موضوعية: Cancer Research, DNA Repair, Chromosomal Proteins, Non-Histone, cohesin, Cell Cycle Proteins, DAPI, 4′,6-Diamidino-2-phenylindole, Immunoglobulin Switch Region, 0302 clinical medicine, ChIP, Chromatin immunoprecipitation, Activation-induced (cytidine) deaminase, AID, Activation-induced cytidine deaminase, Immunology and Allergy, CSR, Class-switch recombination, Gene Rearrangement, 0303 health sciences, 3. Good health, Raji cell, DNA-Binding Proteins, Immunoglobulin Isotypes, Protein Transport, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Protein Binding, Cell Survival, Immunology, CSR-Ds, CSR defects, chemical and pharmacologic phenomena, Biology, Models, Biological, Immunoglobulin Class Switch Recombination, Cell Line, Chromatin remodeling, class-switch recombination defect, 03 medical and health sciences, Immune Deficiencies, Infection, and Systemic Immune Disorders, medicine, GLT, Germ-line transcript, Humans, B cell, 030304 developmental biology, Cohesin, DNA Helicases, Immunologic Deficiency Syndromes, wt, Wild type, Genetic Variation, Gene rearrangement, NHEJ, Non-homologous end joining, Chromatin Assembly and Disassembly, Molecular biology, Immunoglobulin Class Switching, Immunoglobulin class switching, Gene Expression Regulation, TCR, T-cell receptor, CSR synapse, biology.protein, MMR, Mismatch repair, ATPases Associated with Diverse Cellular Activities, Carrier Proteins

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PARP inhibition potentiates the cytotoxic activity of C-1305, a selective inhibitor of topoisomerase II, in human BRCA1-positive breast cancer cells

المؤلفون: Margarita Maurer, Józefa Węsierska-Gądek, Andrzej Skladanowski, Nora Zulehner, Oxana Komina, Franziska Ferk

المصدر: Biochemical Pharmacology

مصطلحات موضوعية: MMP, mitochondrial membrane potential, Poly (ADP-Ribose) Polymerase-1, Apoptosis, BRCA1, breast cancer type 1 susceptibility protein, Biochemistry, PVDF, polyvinylidene difluoride, 0302 clinical medicine, DNA strand breaks, Cytotoxic T cell, Topoisomerase II Inhibitors, skin and connective tissue diseases, BER, base excision repair, 0303 health sciences, G2 arrest, BRCA1 Protein, Caspase 3, Drug Synergism, Cell cycle, 3. Good health, PARP-1, poly(ADP-ribose)polymerase-1, HMC, Hoffman modulation contrast, 030220 oncology & carcinogenesis, Female, Poly(ADP-ribose) Polymerases, TOPO, topoisomerase, Caspase-3 activation, DNA repair, Poly ADP ribose polymerase, Antineoplastic Agents, Breast Neoplasms, Biology, Poly(ADP-ribose) Polymerase Inhibitors, Article, 03 medical and health sciences, Cell Line, Tumor, NER, nucleotide excision repair, Humans, WCL, whole cell lysate, PD, Petri dish, 030304 developmental biology, ComputingMethodologies_COMPUTERGRAPHICS, Cell Proliferation, Pharmacology, Cell growth, Topoisomerase, DNA Breaks, Triazoles, Molecular biology, WT, wild-type, Drug Resistance, Neoplasm, NHEJ, non-homologous end joining, Cancer cell, Cancer research, biology.protein, Potential of mitochondrial membrane, Acridines, Topoisomerase-II Inhibitor, Tumor Suppressor Protein p53, HR, homologous recombination

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a962aa50acdf9a2d56583ca55fbb3435Test
https://pubmed.ncbi.nlm.nih.gov/22906755Test

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