المؤلفون: Kelly Fulk, David E. Goldgar, Steven N. Hart, Tina Pesaran, Marcy E. Richardson, Chunling Hu, Kun Y. Lee, Fergus J. Couch, Elizabeth C. Chao, Ashley Deckman, Alvaro N.A. Monteiro, Kate Durda, Rohan Gnanaolivu, Eric C. Polley, Holly LaDuca

المصدر: American Journal of Human Genetics

مصطلحات موضوعية: 0301 basic medicine, Functional assay, DNA repair, Mutation, Missense, Breast Neoplasms, Computational biology, Biology, Article, Germline, Structure-Activity Relationship, 03 medical and health sciences, breast cancer, 0302 clinical medicine, predisposition gene, Genetics, Humans, Missense mutation, ACMG/AMP, Genetic Predisposition to Disease, Clinical significance, Uncertain significance, Gene, Genetics (clinical), BRCA2 Protein, variant of uncertain significance, Genetic Variation, Recombinational DNA Repair, DNA-binding domain, BRCA2, 030104 developmental biology, 030220 oncology & carcinogenesis, Female, functional assay

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3741ce40310a372ba413ed0e1a66b4dTest
https://doi.org/10.1016/j.ajhg.2021.02.005Test

المؤلفون: Thanh P. Ho, Eric C. Polley, Robert R. McWilliams, William R. Bamlet, Steven N. Hart, Kari G. Rabe, Nicholas J. Boddicker, Pashtoon Murtaza Kasi, Fergus J. Couch, Chunling Hu, Siddhartha Yadav, Kun Y. Lee, Gloria M. Petersen, Tricia Lindstrom, Rohan Gnanaolivu

المصدر: Clin Cancer Res

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, PALB2, Adenocarcinoma, medicine.disease_cause, Article, Germline, 03 medical and health sciences, 0302 clinical medicine, Germline mutation, BARD1, Internal medicine, Biomarkers, Tumor, Humans, Medicine, Genetic Testing, Prospective Studies, Germ-Line Mutation, Aged, Mutation, business.industry, BRIP1, Recombinational DNA Repair, Middle Aged, Prognosis, medicine.disease, Pancreatic Neoplasms, Survival Rate, DNA Repair Enzymes, 030104 developmental biology, 030220 oncology & carcinogenesis, RAD51C, Female, business, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2410bab69ad8c9c00347e305a29bc95Test
https://doi.org/10.1158/1078-0432.ccr-20-1788Test

المؤلفون: Jill S. Dolinsky, Brigette Tippin Davis, David E. Goldgar, Tina Pesaran, Jenna Lilyquist, Jie Na, Holly LaDuca, Amal Yussuf, Nancy Niguidula, Elizabeth C. Chao, Chunling Hu, Hermela Shimelis, Steven N. Hart, Siddhartha Yadav, Fergus J. Couch, Kun Y. Lee, Stephanie Gutierrez, Eric C. Polley

المصدر: JNCI Journal of the National Cancer Institute

مصطلحات موضوعية: Cancer Research, 2019-20 coronavirus outbreak, Ethnic group, Breast Neoplasms, Brief Communication, 03 medical and health sciences, Race (biology), 0302 clinical medicine, Breast cancer, Ethnicity, Humans, Medicine, Genetic Predisposition to Disease, CHEK2, 030304 developmental biology, 0303 health sciences, business.industry, Hispanic or Latino, medicine.disease, Ashkenazi jews, Increased risk, Oncology, Case-Control Studies, 030220 oncology & carcinogenesis, cardiovascular system, Female, Hereditary Cancer, AcademicSubjects/MED00010, business, Demography

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f878a957b7b1952845553924295cf4Test
https://doi.org/10.1093/jnci/djaa167Test

المؤلفون: Loic LeMarchand, Esther M. John, Song Yao, Mia M. Gaudet, Chi Gao, Tuya Pal, Julie R. Palmer, Kimberly A. Bertrand, Payal D. Shah, Rohan Gnanaolivu, Katherine L. Nathanson, Chunling Hu, Susan M. Domchek, Peter Kraft, Jie Na, Leslie Bernstein, Fergus J. Couch, David E Goldgar, Eric C. Polley, Elisa V. Bandera, Dale P. Sandler, Christine B. Ambrosone, Jeffrey N. Weitzel, Amy Trentham-Dietz, Siddhartha Yadav, Steven N. Hart, William Yang, Kun Y. Lee, Christopher A. Haiman, Traci N. Bethea, Hongyan Huang, Hoda Anton-Culver

المصدر: JNCI: Journal of the National Cancer Institute. 112:1213-1221

مصطلحات موضوعية: Oncology, 0303 health sciences, Cancer Research, medicine.medical_specialty, education.field_of_study, medicine.diagnostic_test, business.industry, PALB2, Population, Estrogen receptor, Cancer, Gene mutation, medicine.disease, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, 030220 oncology & carcinogenesis, Internal medicine, medicine, business, education, CHEK2, 030304 developmental biology, Genetic testing

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::2cea0616e2b160899bd3beaa48d6def5Test
https://doi.org/10.1093/jnci/djaa040Test

المؤلفون: Prema P. Peethambaram, Patrick D. Fitz-Gibbon, Siddhartha Yadav, Daniela L. Stan, Sandhya Pruthi, Nicole P. Sandhu, Nicholas J. Boddicker, Sebastian M. Armasu, Judy C. Boughey, Karthik Ghosh, Janet E. Olson, Eric C. Polley, Christine L. Klassen, Kathryn J. Ruddy, Tufia C. Haddad, Deborah J. Rhodes, Rohan Gnanaolivu, Lonzetta Neal, Kun Y. Lee, Steven N. Hart, Matthew P. Goetz, Susan M. Domchek, Chunling Hu, Tanya L. Hoskin, Jie Na, Fergus J. Couch, Tricia Lindstrom

المصدر: Journal of Clinical Oncology

مصطلحات موضوعية: 0301 basic medicine, Oncology, Adult, Cancer Research, medicine.medical_specialty, Genetic Testing for Cancer, MEDLINE, Breast Neoplasms, Sensitivity and Specificity, Germline, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Breast cancer, Internal medicine, Medicine, Humans, Genetic Predisposition to Disease, Genetic Testing, skin and connective tissue diseases, Germ-Line Mutation, Genetic testing, Aged, Aged, 80 and over, BRCA2 Protein, medicine.diagnostic_test, business.industry, BRCA1 Protein, Reproducibility of Results, Hospital based, ORIGINAL REPORTS, Middle Aged, medicine.disease, Hospitals, 030104 developmental biology, 030220 oncology & carcinogenesis, Female, business, Fanconi Anemia Complementation Group N Protein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b8faec2b0a6c83e8ce226384a50661bTest
http://europepmc.org/articles/PMC7193748Test

المؤلفون: Arif B. Ekici, Michael Untch, Matthias Rübner, Steven N. Hart, Matthias W. Beckmann, Kun Y. Lee, Volkmar Müller, Bernhard Volz, Erik Belleville, Markus Wallwiener, Tanja Fehm, Pauline Wimberger, Friedrich Overkamp, Chunling Hu, Diana Lüftner, Peter A. Fasching, Peyman Hadji, Sabrina Uhrig, Arndt Hartmann, Hans Christian Kolberg, Marius Wunderle, Diethelm Wallwiener, Andreas Schneeweiss, Wolfgang Janni, Hans Tesch, Florin Andrei Taran, André Reis, Fergus J. Couch, Sara Y. Brucker, Rohan Gnanaolivu, Siddhartha Yadav, Michael P. Lux, Johannes Ettl, Lothar Häberle, Andreas D. Hartkopf, H Hübner, Eric C. Polley

المصدر: J Clin Oncol

مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Genes, BRCA2, MEDLINE, Genes, BRCA1, Breast Neoplasms, 03 medical and health sciences, 0302 clinical medicine, Germline mutation, Text mining, Internal medicine, medicine, Humans, Clinical significance, In patient, Neoplasm Metastasis, skin and connective tissue diseases, Gene, 030219 obstetrics & reproductive medicine, business.industry, ORIGINAL REPORTS, Middle Aged, medicine.disease, Prognosis, Metastatic breast cancer, 030220 oncology & carcinogenesis, Mutation, Disease characteristics, Female, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69e6ca1ffd7d679c2e5ac4bc49025175Test
https://europepmc.org/articles/PMC8274805Test/

المؤلفون: Jenna Lilyquist, Sean C. Dowdy, Beverly Long, Chunling Hu, Fergus J. Couch, Eric C. Polley, Jamie N. Bakkum-Gamez, Steven N. Hart, Kun Y. Lee, Amy L. Weaver, Rohan Gnanaolivu

المصدر: Gynecologic Oncology. 152:20-25

مصطلحات موضوعية: 0301 basic medicine, Genes, BRCA2, Genes, BRCA1, Gene mutation, Article, Germline, 03 medical and health sciences, 0302 clinical medicine, Germline mutation, medicine, Humans, Genetic Predisposition to Disease, Gene, Allele frequency, Germ-Line Mutation, Aged, business.industry, Endometrial cancer, Obstetrics and Gynecology, Middle Aged, medicine.disease, Lynch syndrome, Endometrial Neoplasms, Serous fluid, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Cancer research, Female, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e224be216cba5a40fa6b105612fb89cTest
https://doi.org/10.1016/j.ygyno.2018.10.019Test

المؤلفون: Kun Y. Lee, Chunling Hu, Kuteesa Job, Jenna Lilyquist, Steven N. Hart, Nicholas J. Boddicker, Sue A. Ingles, Eric C. Polley, Christopher A. Haiman, Lucy Xia, Raed Samara, Xin Sheng, Henry M. Dabanja, Lynne R. Wilkens, George Mutema, Benon Masaba, Loic Le Marchand, Rohan Gnanaolivu, Alexander Lubmawa, Dan Namuguzi, Marco Matejcic, David V. Conti, Stephen Watya, Yesha Patel, Siddhartha Yadav, Vicky Kiddu, Fergus J. Couch

المصدر: JCO Precis Oncol

مصطلحات موضوعية: 0301 basic medicine, Prostate cancer risk, Oncology, Cancer Research, medicine.medical_specialty, Cancer predisposition, business.industry, DNA Repair Pathway, medicine.disease, Article, 03 medical and health sciences, Prostate cancer, 030104 developmental biology, 0302 clinical medicine, 030220 oncology & carcinogenesis, Internal medicine, medicine, business, Gene

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd33bc98019289e06bc7ea939251e2a9Test
https://pubmed.ncbi.nlm.nih.gov/32832836Test

المؤلفون: Seung-Ho Shin, Abhijit Chakraborty, Qiushi Wang, Souren Paul, Eunmiri Roh, Tianshun Zhang, Hisae Yoshitomi, Zigang Dong, H. S. Chen, Joohyun Ryu, Faisal Aziz, Ke Yao, Kun Y. Lee, Ann M. Bode

المصدر: Cancer research. 81(4)

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Codon, Initiator, Wilms Tumor, law.invention, 03 medical and health sciences, Mice, 0302 clinical medicine, Ubiquitin, GSK-3, law, Animals, Humans, Protein Isoforms, FBXW8, Phosphorylation, WT1 Proteins, Cells, Cultured, Glycogen Synthase Kinase 3 beta, biology, Oncogene, HEK 293 cells, Ubiquitination, Oncogenes, Kidney Neoplasms, Gene Expression Regulation, Neoplastic, Mice, Inbred C57BL, 030104 developmental biology, HEK293 Cells, Oncology, Tumor progression, A549 Cells, 030220 oncology & carcinogenesis, Proteolysis, biology.protein, Cancer research, Disease Progression, Suppressor, Female, Protein Processing, Post-Translational, HeLa Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8009033a5e9085e66135e3b81c3a04e2Test
https://pubmed.ncbi.nlm.nih.gov/33184107Test

المؤلفون: David W. Hillman, Siddhartha Yadav, Kun Y. Lee, Steven N. Hart, Manish Kohli, Jie Na, Eric C. Polley, Fergus J. Couch, Rohan Gnanaolivu, Chunling Hu

المصدر: JCO Precis Oncol

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, DNA repair, business.industry, medicine.disease, Hormone-sensitive, 03 medical and health sciences, Prostate cancer, 030104 developmental biology, 0302 clinical medicine, Castrate resistant, Germline mutation, Oncology, 030220 oncology & carcinogenesis, medicine, Cancer research, Original Report, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50fe8b791364b63208d26f6c86dabfcfTest
https://europepmc.org/articles/PMC7446380Test/