نتائج البحث - "ABIRATERONE"

1

Efficacy and safety of abiraterone acetate plus prednisolone in patients with early metastatic castration-resistant prostate cancer who failed first-line androgen-deprivation therapy: a single-arm, phase 4 study

المؤلفون: H Kobayashi, M Iinuma, Hiroomi Nakatsu, Kazuo Mikami, Takefumi Satoh, A Maniwa, H Kikukawa, Naoto Kamiya, Koichi Kobayashi, Kenneth K. Tanabe, T Nakashima, N Okuno, Yasutomo Nasu, Hirotsugu Uemura, Gaku Arai, Junya Furukawa

المصدر: Japanese Journal of Clinical Oncology

مصطلحات موضوعية: Male, Cancer Research, medicine.medical_specialty, Prednisolone, Urology, Abiraterone Acetate, abiraterone acetate, chemotherapy-naive metastatic castration-resistant prostate cancer, Kaplan-Meier Estimate, Androgen deprivation therapy, 03 medical and health sciences, Prostate cancer, chemistry.chemical_compound, 0302 clinical medicine, Castration Resistance, Antineoplastic Combined Chemotherapy Protocols, medicine, AcademicSubjects/MED00300, prostate-specific antigen, Humans, Radiology, Nuclear Medicine and imaging, 030212 general & internal medicine, Neoplasm Metastasis, Adverse effect, Aged, Aged, 80 and over, business.industry, Abiraterone acetate, General Medicine, Middle Aged, medicine.disease, Chemotherapy regimen, Progression-Free Survival, Prostate-specific antigen, Prostatic Neoplasms, Castration-Resistant, Treatment Outcome, Oncology, chemistry, 030220 oncology & carcinogenesis, Androgens, Original Article, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4f85ac0065f8e062ccb5fa949c1f5d2Test
http://europepmc.org/articles/PMC8012350Test

2

Role of androgen receptor splice variant-7 (AR-V7) in prostate cancer resistance to 2nd-generation androgen receptor signaling inhibitors

المؤلفون: Susan L. Dalrymple, Yezi Zhu, Peter S. Nelson, Jun Luo, Jianfeng Xu, Alan K. Meeker, Samuel R. Denmeade, Emmanuel S. Antonarakis, S. Lilly Zheng, William B. Isaacs, Angelo M. De Marzo, Jody E. Hooper, Ilsa Coleman, John T. Isaacs, W. Nathaniel Brennen

المصدر: Oncogene

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Biopsy, RNA Splicing, Abiraterone Acetate, medicine.disease_cause, Article, Gene Knockout Techniques, Mice, 03 medical and health sciences, Prostate cancer, chemistry.chemical_compound, 0302 clinical medicine, Cell Line, Tumor, Nitriles, Phenylthiohydantoin, Genetics, medicine, Animals, Humans, Protein Isoforms, PTEN, Enzalutamide, RNA-Seq, Receptor, Molecular Biology, Aged, Regulation of gene expression, Mutation, biology, Prostate, Abiraterone acetate, Androgen Antagonists, Middle Aged, medicine.disease, Xenograft Model Antitumor Assays, Gene Expression Regulation, Neoplastic, Androgen receptor, Prostatic Neoplasms, Castration-Resistant, 030104 developmental biology, chemistry, Drug Resistance, Neoplasm, Receptors, Androgen, 030220 oncology & carcinogenesis, Benzamides, biology.protein, Cancer research

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3571a984b57691572f6678e3f0d4d0d6Test
https://doi.org/10.1038/s41388-020-01479-6Test

3

CYP17A1 polymorphism c.-362T>C predicts clinical outcome in metastatic castration-resistance prostate cancer patients treated with abiraterone

المؤلفون: Lorenzo Fontanelli, Romano Danesi, Federico Cucchiara, Luca Galli, Marzia Del Re, Federico Paolieri, Francesco Bloise, Andrea Sbrana, Chiara Mercinelli, Stefania Crucitta, Enrico Sammarco

المصدر: Cancer Chemotherapy and Pharmacology. 86:527-533

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Cancer Research, Abiraterone Acetate, Abiraterone, CRPC, CYP17A1, Pharmacogenetics, Polymorphism, Kaplan-Meier Estimate, Toxicology, Prostate cancer, 0302 clinical medicine, Castration Resistance, Pharmacology (medical), Aged, 80 and over, Univariate analysis, Prostate, Steroid 17-alpha-Hydroxylase, Middle Aged, Prognosis, Progression-Free Survival, Prostatic Neoplasms, Castration-Resistant, 030220 oncology & carcinogenesis, Cohort, Disease Progression, Hormonal therapy, Kallikreins, medicine.medical_specialty, Single-nucleotide polymorphism, Adenocarcinoma, Polymorphism, Single Nucleotide, 03 medical and health sciences, Internal medicine, Biomarkers, Tumor, medicine, Humans, Aged, Retrospective Studies, Pharmacology, business.industry, Prostate-Specific Antigen, medicine.disease, 030104 developmental biology, Drug Resistance, Neoplasm, Neoplasm Grading, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f364467513bdbd1dfb69ed0829f6fa26Test
https://doi.org/10.1007/s00280-020-04133-wTest

4

Clinical outcomes, management, and treatment patterns in patients with metastatic castration‐resistant prostate cancer treated with radium‐223 in community compared to academic settings

المؤلفون: Sreevalsa Appukkuttan, Oliver Sartor, Che-Kai Tsao, Jeffrey Weiss

المصدر: The Prostate

مصطلحات موضوعية: Male, 0301 basic medicine, Subset Analysis, Radium-223, medicine.medical_specialty, radium‐223, Urology, medicine.medical_treatment, Bone Neoplasms, castration resistance, 03 medical and health sciences, chemistry.chemical_compound, Prostate cancer, 0302 clinical medicine, bone metastases, Internal medicine, Clinical endpoint, medicine, Humans, Enzalutamide, Community Health Services, Aged, Retrospective Studies, Aged, 80 and over, Academic Medical Centers, Chemotherapy, business.industry, Abiraterone acetate, Disease Management, Original Articles, Middle Aged, prostate cancer, real‐world data, medicine.disease, Discontinuation, Survival Rate, Prostatic Neoplasms, Castration-Resistant, Treatment Outcome, 030104 developmental biology, Oncology, chemistry, 030220 oncology & carcinogenesis, Original Article, business, Follow-Up Studies, Radium, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c839aa0768ff85d4e97366ab2db2095Test
https://doi.org/10.1002/pros.24143Test

5

Clinical outcomes of abiraterone acetate and predictors of its treatment duration in metastatic castration‐resistant prostate cancer: Real‐world experience in the Southeast Asian cohort

المؤلفون: Bannakij Lojanapiwat, Supon Sriplakich, Nisha Shariff, Shankaran Thevarajah, Marniza Saad, Jaraspong Vuthiwong, Adeline Mathew, Firdaus Ahmayuddin, Teng Aik Ong, Jasmine Lim, Akara Amantakul, Flora Li Tze Chong, Adlinda Alip

المصدر: Cancer Medicine, Vol 9, Iss 13, Pp 4613-4621 (2020)
Cancer Medicine

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Abiraterone Acetate, chemotherapy, Gastroenterology, Cohort Studies, Prostate cancer, chemistry.chemical_compound, 0302 clinical medicine, Original Research, Hazard ratio, Abiraterone acetate, Middle Aged, Thailand, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Progression-Free Survival, Prostatic Neoplasms, Castration-Resistant, Treatment Outcome, Oncology, 030220 oncology & carcinogenesis, Cohort, Kallikreins, medicine.medical_specialty, overall survival, Antineoplastic Agents, Southeast asian, Lower risk, lcsh:RC254-282, 03 medical and health sciences, Internal medicine, Statistical significance, medicine, Humans, Radiology, Nuclear Medicine and imaging, Progression-free survival, Aged, Proportional Hazards Models, Duration of Therapy, business.industry, Malaysia, Clinical Cancer Research, progression‐free survival, PSA response, Prostate-Specific Antigen, medicine.disease, 030104 developmental biology, chemistry, Multivariate Analysis, Neoplasm Grading, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba19a11f1ec645c379b8affeca6b3f52Test
https://doaj.org/article/79a4ccc9b606452cb59da5839852368fTest

6

Concomitant intake of abiraterone acetate and food to increase pharmacokinetic exposure: real life data from a therapeutic drug monitoring programme

المؤلفون: Merel van Nuland, Andries M. Bergman, Vincent O. Dezentjé, Alwin D. R. Huitema, Neeltje Steeghs, Stefanie L. Groenland, Jeantine M de Feijter, Jos H. Beijnen, Hilde Rosing

المصدر: European Journal of Cancer, 130, 32. Elsevier Ltd

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c548b45b4c1406b84161e72341410bTest
https://doi.org/10.1016/j.ejca.2020.02.012Test

7

Liver tests increase on abiraterone acetate in men with metastatic prostate cancer: Natural history, management and outcome

المؤلفون: Edith Carton, Yohann Loriot, Grégoire Marret, Karim Fizazi, Pernelle Lavaud, Giulia Baciarello, Stéphane Culine, Emeline Colomba, Christophe Massard, Olivier Huillard, Laurence Albiges, Jérôme Alexandre

المصدر: European Journal of Cancer. 129:117-122

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, medicine.medical_specialty, Remission, Spontaneous, Abiraterone Acetate, Administration, Oral, Bone Neoplasms, Gastroenterology, Drug Administration Schedule, Liver disorder, Transaminase, 03 medical and health sciences, chemistry.chemical_compound, Prostate cancer, 0302 clinical medicine, Liver Function Tests, Prednisone, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Aspartate Aminotransferases, Aged, Aged, 80 and over, Dose-Response Relationship, Drug, medicine.diagnostic_test, business.industry, Incidence, Liver Neoplasms, Abiraterone acetate, Alanine Transaminase, Common Terminology Criteria for Adverse Events, Middle Aged, medicine.disease, Discontinuation, Prostatic Neoplasms, Castration-Resistant, 030104 developmental biology, Oncology, chemistry, Lymphatic Metastasis, 030220 oncology & carcinogenesis, Chemical and Drug Induced Liver Injury, business, Liver function tests, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::776b72d2a13a80ac9e7e33dedcfe8d70Test
https://doi.org/10.1016/j.ejca.2020.01.017Test

8

Efficacy and safety of abiraterone acetate plus prednisone in Japanese patients with newly diagnosed, metastatic hormone-naive prostate cancer: final subgroup analysis of LATITUDE, a randomized, double-blind, placebo-controlled, phase 3 study

المؤلفون: Suneel Mundle, Namphuong Tran, Toshitaka Shin, Kazuhiro Shibayama, Satoshi Fukasawa, Nobuaki Matsubara, Hiroyoshi Suzuki, Noriyuki Ohtake, Sumiko Kitani, Katsuyoshi Hashine, Karim Fizazi

المصدر: Japanese Journal of Clinical Oncology

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, medicine.medical_specialty, Population, Abiraterone Acetate, Antineoplastic Agents, Subgroup analysis, Placebo, Gastroenterology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Double-Blind Method, Japan, Prednisone, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, AcademicSubjects/MED00300, metastatic hormone-naïve prostate cancer, Radiology, Nuclear Medicine and imaging, Progression-free survival, Neoplasm Metastasis, education, Aged, education.field_of_study, business.industry, Hazard ratio, Abiraterone acetate, Prostatic Neoplasms, General Medicine, Middle Aged, Interim analysis, Survival Analysis, 030104 developmental biology, Oncology, chemistry, 030220 oncology & carcinogenesis, Original Article, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::300a832303c29c8960d2484389970412Test
https://doi.org/10.1093/jjco/hyaa030Test

9

Plasma cell-free DNA–based predictors of response to abiraterone acetate/prednisone and prognostic factors in metastatic castration-resistant prostate cancer

المؤلفون: Yijun Tian, Liewei Wang, Meijun Du, Manish Kohli, Winston Tan, Deepak Kilari, Liang Wang, Chiang Ching Huang, Liguo Wang

المصدر: Prostate cancer and prostatic diseases

مصطلحات موضوعية: Oncology, Male, Cancer Research, 030232 urology & nephrology, abiraterone acetate and prednisone, Abiraterone Acetate, Anti-Inflammatory Agents, Steroid Synthesis Inhibitors, Plasma cell, chemistry.chemical_compound, Prostate cancer, 0302 clinical medicine, Prostate, Prednisone, Neoplasm Metastasis, Fisher's exact test, copy number alterations, Abiraterone acetate, Middle Aged, Survival Rate, Prostatic Neoplasms, Castration-Resistant, medicine.anatomical_structure, Treatment Outcome, 030220 oncology & carcinogenesis, symbols, Kallikreins, Cell-Free Nucleic Acids, medicine.drug, Adult, medicine.medical_specialty, low-pass whole genome sequencing, DNA Copy Number Variations, Urology, overall survival, Article, cell-free DNA, 03 medical and health sciences, symbols.namesake, Internal medicine, medicine, Biomarkers, Tumor, Humans, primary resistance, Survival analysis, Aged, business.industry, Proportional hazards model, acquired resistance, Prostate-Specific Antigen, medicine.disease, Metastatic castration-resistant prostate cancer, chemistry, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b769a7e4ff11e764231e5b05cc17ff5fTest
http://europepmc.org/articles/PMC7501185Test

10

A candidate androgen signalling signature predictive of response to abiraterone acetate in men with metastatic castration-resistant prostate cancer

المؤلفون: John C. Araujo, Christopher J. Logothetis, Jeri Kim, Eleni Efstathiou, Justin A. Weldon, Ana Aparicio, Lance C. Pagliaro, Jennifer L. Wang, Nicholas Spetsieris, Alexandros Tsikkinis, Paul G. Corn, Sijin Wen, Anh G Hoang, Shi Ming Tu, Nizar M. Tannir, Sumit K. Subudhi, Myrto Boukovala, Amado J. Zurita, Patricia Troncoso

المصدر: Eur J Cancer

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, medicine.drug_class, Abiraterone Acetate, Article, 03 medical and health sciences, chemistry.chemical_compound, Prostate cancer, 0302 clinical medicine, Internal medicine, Biomarkers, Tumor, medicine, Humans, Prospective Studies, Neoplasm Metastasis, Aged, Aged, 80 and over, business.industry, Sunitinib, Abiraterone acetate, Bone metastasis, Androgen Antagonists, Middle Aged, Prognosis, medicine.disease, Androgen, Androgen receptor, Dasatinib, Prostatic Neoplasms, Castration-Resistant, 030104 developmental biology, medicine.anatomical_structure, ROC Curve, chemistry, Receptors, Androgen, 030220 oncology & carcinogenesis, Bone marrow, business, Follow-Up Studies, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::017fe1842dd3c6412e933a86e6c6d94bTest
https://doi.org/10.1016/j.ejca.2019.12.027Test

تنقيح النتائج