نتائج البحث

1

Pembrolizumab Plus Ipilimumab Following Anti-PD-1/L1 Failure in Melanoma

المصدر: J Clin Oncol

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53f50387d5994f75ceeba750e8bc2f9Test
https://doi.org/10.1200/jco.21.00079Test

2

Blocking hsa_circ_0006168 suppresses cell proliferation and motility of human glioblastoma cells by regulating hsa_circ_0006168/miR-628-5p/IGF1R ceRNA axis

المؤلفون: Ke Gao, Chen Chen, Bin Zhang, Bo Cui, Mingjie Xu, Mao Ping, Yong Feng, Tuo Wang

المصدر: Cell Cycle

مصطلحات موضوعية: Male, 0301 basic medicine, MAPK/ERK pathway, MAP Kinase Signaling System, medicine.medical_treatment, Down-Regulation, Mice, Nude, Apoptosis, Biology, Transfection, Receptor, IGF Type 1, Mice, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Cell Movement, Cell Line, Tumor, microRNA, medicine, Animals, Humans, Gene Silencing, Molecular Biology, Cell Proliferation, Insulin-like growth factor 1 receptor, Mice, Inbred BALB C, Gene knockdown, Brain Neoplasms, Cell growth, Growth factor, RNA, Circular, Cell Biology, Middle Aged, Xenograft Model Antitumor Assays, Tumor Burden, Up-Regulation, Blot, MicroRNAs, 030104 developmental biology, Case-Control Studies, 030220 oncology & carcinogenesis, Cancer research, Female, Glioblastoma, Research Paper, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a78e9b859accdb459b8baf410778499cTest
https://doi.org/10.1080/15384101.2021.1930357Test

3

Lipase elevation and type 1 diabetes mellitus related to immune checkpoint inhibitor therapy – A multicentre study of 90 patients from the German Dermatooncology Group

المؤلفون: Michael Momma, Carmen Loquai, Cristel Ruini, Corinna Kochanek, Kai-Martin Thoms, Selma Ugurel, Carola Berking, Lisa Zimmer, Friedegund Meier, Katharina C. Kähler, Lucie Heinzerling, Dirk Debus, Jessica C. Hassel, Imke Grimmelmann, Claudia Pföhler, Jochen Utikal, Rudolf A. Herbst, Thomas Eigentler, Ralf Gutzmer

المصدر: European Journal of Cancer. 149:1-10

مصطلحات موضوعية: Adult, Blood Glucose, Male, 0301 basic medicine, Cancer Research, medicine.medical_specialty, Skin Neoplasms, Time Factors, Medizin, Gastroenterology, Thyroiditis, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Predictive Value of Tests, Germany, Internal medicine, Diabetes mellitus, medicine, Humans, Lipase, Adverse effect, Immune Checkpoint Inhibitors, Melanoma, Aged, Retrospective Studies, Aged, 80 and over, Type 1 diabetes, biology, business.industry, Diabetes, Immune checkpoint inhibitors, Immune-related adverse events, Ipilimumab, Nivolumab, Pancreatitis, PD-1 inhibitor, Pembrolizumab, Biomarkers, Diabetes Mellitus, Type 1, Exocrine Pancreatic Insufficiency, Female, Middle Aged, Treatment Outcome, Up-Regulation, medicine.disease, Ketoacidosis, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, biology.protein, Skin cancer, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46f4bea919fbf1345c4e5a2fd89e7ccTest
https://doi.org/10.1016/j.ejca.2021.02.017Test

4

RUNX2 promotes malignant progression in gastric cancer by regulating COL1A1

المؤلفون: Ran Sun, Xiulan Zhao, Baocun Sun, Yanlei Li

المصدر: Cancer Biomarkers. :1-12

مصطلحات موضوعية: Male, musculoskeletal diseases, 0301 basic medicine, Cancer Research, Extracellular matrix component, Core Binding Factor Alpha 1 Subunit, Biology, Transfection, Metastasis, 03 medical and health sciences, 0302 clinical medicine, stomatognathic system, Downregulation and upregulation, Stomach Neoplasms, Genetics, medicine, Humans, Neoplasm Metastasis, Gene knockdown, musculoskeletal, neural, and ocular physiology, Cancer, General Medicine, Middle Aged, musculoskeletal system, medicine.disease, Collagen Type I, alpha 1 Chain, RUNX2, Collagen, type I, alpha 1, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, embryonic structures, Disease Progression, Cancer research, Immunohistochemistry, Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f9dc6505e1fd531de65dba695073d6Test
https://doi.org/10.3233/cbm-200472Test

5

A novel osimertinib-resistant human lung adenocarcinoma cell line harbouring mutant EGFR and activated IGF1R

المؤلفون: Yoshinobu Maeda, Yuka Kato, Kammei Rai, Toshio Kubo, Masahiro Tabata, Eiki Ichihara, Kiichiro Ninomiya, Go Makimoto, Katsuyuki Kiura, Katsuyuki Hotta, Ryota Sunami, Kadoaki Ohashi

المصدر: Japanese Journal of Clinical Oncology. 51:956-965

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Lung Neoplasms, medicine.drug_class, Adenocarcinoma of Lung, Tyrosine-kinase inhibitor, Receptor, IGF Type 1, 03 medical and health sciences, T790M, 0302 clinical medicine, Gefitinib, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, medicine, Humans, Radiology, Nuclear Medicine and imaging, Osimertinib, Epidermal growth factor receptor, Protein Kinase Inhibitors, Insulin-like growth factor 1 receptor, Acrylamides, Aniline Compounds, biology, business.industry, General Medicine, Middle Aged, medicine.disease, respiratory tract diseases, ErbB Receptors, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Mutation, Cancer research, biology.protein, Adenocarcinoma, Female, business, Tyrosine kinase, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86de64c92057b81ca0840e088d83d5bdTest
https://doi.org/10.1093/jjco/hyab048Test

6

Efficacy of Decitabine plus Anti-PD-1 Camrelizumab in Patients with Hodgkin Lymphoma Who Progressed or Relapsed after PD-1 Blockade Monotherapy

المؤلفون: Miao Liu, Malcolm V. Brock, Qingming Yang, Fengxia Shi, Jing Nie, Liang Dong, Jiejie Liu, Weidong Han, Qian Mei, Chunmeng Wang, Yang Liu, Xiang Li, Meixia Chen

المصدر: Clinical Cancer Research. 27:2782-2791

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Cancer Research, medicine.medical_specialty, Adolescent, Programmed Cell Death 1 Receptor, Decitabine, Kaplan-Meier Estimate, Antibodies, Monoclonal, Humanized, Gastroenterology, B7-H1 Antigen, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Refractory, Recurrence, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, In patient, Child, Neoplasm Staging, business.industry, Anti pd 1, Middle Aged, Prognosis, Hodgkin Disease, Blockade, Treatment Outcome, 030104 developmental biology, Oncology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Retreatment, Cohort, Disease Progression, Pd 1 blockade, Hodgkin lymphoma, Female, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e09f7bc2baaa5514edccb162437f68Test
https://doi.org/10.1158/1078-0432.ccr-21-0133Test

7

Integration of comprehensive genomic profiling, tumor mutational burden, and PD‐L1 expression to identify novel biomarkers of immunotherapy in non‐small cell lung cancer

المؤلفون: Shiyue Zhang, Youming Lei, Juan Zhao, Songhui Zhao, Wen-Jing Wang, Ming Yao, Xiaowei Dong, Kai Wang, Li Liu, Qing Zhou, Yunfei Shi

المصدر: Cancer Medicine
Cancer Medicine, Vol 10, Iss 7, Pp 2216-2231 (2021)

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Lung Neoplasms, medicine.medical_treatment, medicine.disease_cause, Immunotherapy, Adoptive, B7-H1 Antigen, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Medicine, tumor protein p53, Anaplastic Lymphoma Kinase, Copy-number variation, programmed cell death 1 ligand 1, Immune Checkpoint Inhibitors, Original Research, Gene Rearrangement, education.field_of_study, High-Throughput Nucleotide Sequencing, Genetic Profile, Middle Aged, Protein-Tyrosine Kinases, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lysine methyltransferase 2C, Progression-Free Survival, Oncology, 030220 oncology & carcinogenesis, Biomarker (medicine), Female, KRAS, non‐small cell lung cancer, Genetic Markers, China, Population, tumor mutation burden, lcsh:RC254-282, 03 medical and health sciences, Proto-Oncogene Proteins, ROS1, Biomarkers, Tumor, Humans, Radiology, Nuclear Medicine and imaging, education, Lung cancer, Aged, Retrospective Studies, business.industry, Proto-Oncogene Proteins c-ret, Cancer, Clinical Cancer Research, Immunotherapy, Genes, erbB-1, Histone-Lysine N-Methyltransferase, medicine.disease, Genes, p53, 030104 developmental biology, Genes, ras, Mutation, Cancer research, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07246db02928c9d4cd88d3dfd21b1b9dTest
http://europepmc.org/articles/PMC7982619Test

8

Mechanistic insights into immune checkpoint inhibitor-related hypophysitis: a form of paraneoplastic syndrome

المؤلفون: Ryusaku Matsumoto, Masaaki Yamamoto, Genzo Iguchi, Shin Urai, Hidenori Fukuoka, Wataru Ogawa, Kentaro Suda, Hiroki Shichi, Keitaro Kanie, Yutaka Takahashi, Hironori Bando, Yasunori Fujita

المصدر: Cancer Immunology, Immunotherapy

مصطلحات موضوعية: Male, Cancer Research, Pro-Opiomelanocortin, Paraneoplastic Syndromes, Programmed Cell Death 1 Receptor, Autoimmunity, Hypopituitarism, Immune checkpoint inhibitor, medicine.disease_cause, B7-H1 Antigen, Mice, 0302 clinical medicine, Neoplasms, Immunology and Allergy, CTLA-4 Antigen, Corticotrophs, Immune Checkpoint Inhibitors, Aged, 80 and over, biology, Middle Aged, Oncology, 030220 oncology & carcinogenesis, Paraneoplastic syndrome, Female, Original Article, Immunotherapy, Antibody, hormones, hormone substitutes, and hormone antagonists, Adult, endocrine system, Hypophysitis, Immunology, 030209 endocrinology & metabolism, Adrenocorticotropic hormone, 03 medical and health sciences, Antigen, medicine, Animals, Humans, Aged, Retrospective Studies, business.industry, medicine.disease, biology.protein, Ectopic expression, Corticotropic cell, business, Adrenal Insufficiency

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3acc181a81511e7fe6b828ea748faa32Test
https://hdl.handle.net/20.500.14094/90008773Test

9

First‐line pembrolizumab vs chemotherapy in metastatic non‐small‐cell lung cancer: KEYNOTE‐024 Japan subset*

المصدر: Cancer Science
Cancer Sci

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Lung Neoplasms, medicine.medical_treatment, Programmed Cell Death 1 Receptor, non‐small‐cell lung carcinoma, Pembrolizumab, Kaplan-Meier Estimate, Gastroenterology, Deoxycytidine, B7-H1 Antigen, Carboplatin, 0302 clinical medicine, Antineoplastic Agents, Immunological, Japan, Carcinoma, Non-Small-Cell Lung, Antineoplastic Combined Chemotherapy Protocols, Anaplastic Lymphoma Kinase, Neoplasm Metastasis, Aged, 80 and over, Cross-Over Studies, Hazard ratio, General Medicine, Middle Aged, PD-L1 protein, Progression-Free Survival, Oncology, 030220 oncology & carcinogenesis, non-small-cell lung carcinoma, Carcinoma, Squamous Cell, Female, Original Article, Non small cell, pembrolizumab, Adult, medicine.medical_specialty, Paclitaxel, First line, Pemetrexed, Antibodies, Monoclonal, Humanized, Drug Administration Schedule, 03 medical and health sciences, Drug Therapy, Clinical Research, Internal medicine, medicine, Confidence Intervals, Humans, Lung cancer, Adverse effect, PD‐L1 protein, Aged, Chemotherapy, business.industry, Genes, erbB-1, Original Articles, medicine.disease, Survival Analysis, Gemcitabine, Confidence interval, Retraction, 030104 developmental biology, treatment outcome, Cisplatin, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4692f872031566a6ba7ec9528f7d1191Test
https://doi.org/10.1111/cas.15144Test

10

The expression and clinical prognostic value of protein phosphatase 1 catalytic subunit beta in pancreatic cancer

المؤلفون: Zhengxiang Zhong, Lingyu Hu, Bin Wu, Fei Chen, Wei Chen, Yong Gao, Haokai Xu, Xiaoguang Wang

المصدر: Bioengineered
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 1, Pp 2763-2778 (2021)

مصطلحات موضوعية: Male, 0301 basic medicine, Bioinformatics analysis, Protein subunit, Bioengineering, Malignancy, Applied Microbiology and Biotechnology, 03 medical and health sciences, 0302 clinical medicine, Protein Phosphatase 1, Pancreatic cancer, Biomarkers, Tumor, pancreatic adenocarcinoma, medicine, Humans, Beta (finance), Survival rate, business.industry, Computational Biology, Protein phosphatase 1, General Medicine, Middle Aged, Prognosis, medicine.disease, Pancreatic Neoplasms, 030104 developmental biology, protein phosphatase 1 catalytic subunit beta, 030220 oncology & carcinogenesis, Cancer research, Female, Transcriptome, business, TP248.13-248.65, Research Article, Research Paper, Biotechnology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2b16adddb71abed7daa2920defcc4f5Test
https://doi.org/10.1080/21655979.2021.1934243Test

تنقيح النتائج