نتائج البحث

1

Mechanistic insights into immune checkpoint inhibitor-related hypophysitis: a form of paraneoplastic syndrome

المؤلفون: Ryusaku Matsumoto, Masaaki Yamamoto, Genzo Iguchi, Shin Urai, Hidenori Fukuoka, Wataru Ogawa, Kentaro Suda, Hiroki Shichi, Keitaro Kanie, Yutaka Takahashi, Hironori Bando, Yasunori Fujita

المصدر: Cancer Immunology, Immunotherapy

مصطلحات موضوعية: Male, Cancer Research, Pro-Opiomelanocortin, Paraneoplastic Syndromes, Programmed Cell Death 1 Receptor, Autoimmunity, Hypopituitarism, Immune checkpoint inhibitor, medicine.disease_cause, B7-H1 Antigen, Mice, 0302 clinical medicine, Neoplasms, Immunology and Allergy, CTLA-4 Antigen, Corticotrophs, Immune Checkpoint Inhibitors, Aged, 80 and over, biology, Middle Aged, Oncology, 030220 oncology & carcinogenesis, Paraneoplastic syndrome, Female, Original Article, Immunotherapy, Antibody, hormones, hormone substitutes, and hormone antagonists, Adult, endocrine system, Hypophysitis, Immunology, 030209 endocrinology & metabolism, Adrenocorticotropic hormone, 03 medical and health sciences, Antigen, medicine, Animals, Humans, Aged, Retrospective Studies, business.industry, medicine.disease, biology.protein, Ectopic expression, Corticotropic cell, business, Adrenal Insufficiency

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3acc181a81511e7fe6b828ea748faa32Test
https://hdl.handle.net/20.500.14094/90008773Test

2

Cytokine-like protein 1–induced survival of monocytes suggests a combined strategy targeting MCL1 and MAPK in CMML

المساهمون: Institut d'Histoire et de Philosophie des Sciences et des Techniques (IHPST), Université Paris 1 Panthéon-Sorbonne (UP1)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Blood
Blood, American Society of Hematology, 2021, 137 (24), pp.3390-3402. ⟨10.1182/blood.2020008729⟩

مصطلحات موضوعية: Adult, Male, MAPK/ERK pathway, CCR2, Myeloid, Cell Survival, MAP Kinase Signaling System, [SDV]Life Sciences [q-bio], Immunology, Chronic myelomonocytic leukemia, Biochemistry, Monocytes, 03 medical and health sciences, Chemokine receptor, 0302 clinical medicine, hemic and lymphatic diseases, medicine, Humans, MCL1, Extracellular Signal-Regulated MAP Kinases, Autocrine signalling, Protein Kinase Inhibitors, Aged, 030304 developmental biology, Aged, 80 and over, 0303 health sciences, Kinase, Chemistry, [SHS.PHIL]Humanities and Social Sciences/Philosophy, Leukemia, Myelomonocytic, Chronic, Blood Proteins, Cell Biology, Hematology, Middle Aged, medicine.disease, Xenograft Model Antitumor Assays, 3. Good health, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cancer research, Cytokines, Myeloid Cell Leukemia Sequence 1 Protein, Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a876fc49ce5e247d9cb91a3a300a22Test
https://doi.org/10.1182/blood.2020008729Test

3

SAMHD1 expression is associated with low immune activation but not correlated with HIV‑1 DNA levels in CD4+ T cells of patients with HIV‑1

المؤلفون: Jie Li, Longteng Jin, Shanshan Huang, Chuanhua Gao, Changzhong Jin

المصدر: Molecular Medicine Reports

مصطلحات موضوعية: Adult, CD4-Positive T-Lymphocytes, Male, 0301 basic medicine, Cancer Research, HIV Infections, HIV-1 DNA, Biology, Biochemistry, Peripheral blood mononuclear cell, Gene Expression Regulation, Enzymologic, elite controllers, immune activation, SAM Domain and HD Domain-Containing Protein 1, 03 medical and health sciences, 0302 clinical medicine, Genetics, Humans, sterile α motif and histidine/aspartic acid domain-containing protein 1, Molecular Biology, Gene, Regulation of gene expression, Oncogene, Interferon-alpha, Articles, Middle Aged, Viral Load, Cell cycle, Reverse transcriptase, 030104 developmental biology, Anti-Retroviral Agents, Oncology, Apoptosis, 030220 oncology & carcinogenesis, DNA, Viral, Immunology, HIV-1, Leukocytes, Mononuclear, RNA, Viral, Molecular Medicine, Female, SAMHD1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::779b8ae7dcad85cf36332ff19bee6b43Test
https://doi.org/10.3892/mmr.2020.11153Test

4

Association of cancer progression with elevated expression of programmed cell death protein 1 ligand 1 by upper tract urothelial carcinoma and increased tumor-infiltrating lymphocyte density

المؤلفون: Kyoko Arai, Takao Kamai, Akinori Nukui, Minoru Kobayashi, Hideo Yuki, Takahiro Narimatsu, Yoshitatsu Fukabori, Toshiki Kijima, Ken-Ichiro Yoshida, Hideyuki Abe, Tsunehito Kambara, Hironori Betsunoh, Masahiro Yashi

المصدر: Cancer Immunology, Immunotherapy

مصطلحات موضوعية: Male, Cancer Research, Lymphocyte, Kidney, Nephroureterectomy, B7-H1 Antigen, Immune tolerance, 0302 clinical medicine, Tumor Microenvironment, Neutrophil-to-lymphocyte ratio (NLR), Immunology and Allergy, Stage (cooking), Aged, 80 and over, 0303 health sciences, Univariate analysis, Middle Aged, Prognosis, Kidney Neoplasms, Progression-Free Survival, Programmed cell death 1 ligand 1 (PD-L1), medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Upper tract urothelial carcinoma (UTUC), Disease Progression, Immunohistochemistry, Female, Original Article, Tumor-infiltrating lymphocyte (TIL), Adult, Immunology, 03 medical and health sciences, Lymphocytes, Tumor-Infiltrating, medicine, Humans, Aged, Retrospective Studies, 030304 developmental biology, Carcinoma, Transitional Cell, Tumor microenvironment, Ureteral Neoplasms, Tumor-infiltrating lymphocytes, business.industry, Cancer, medicine.disease, Cancer research, Neoplasm Grading, Ureter, business, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a089064114954a8996f5b69f009caefTest
https://doi.org/10.1007/s00262-020-02499-7Test

5

Organ-specific autoantibodies in Chinese patients newly diagnosed with type 1 diabetes mellitus

المؤلفون: Zhiguang Zhou, Zhiguo Xie, Xiajie Shi, Shan Pan, Ting Wu, Gan Huang

المصدر: Endocrine Journal. 67:793-802

مصطلحات موضوعية: Male, endocrine system diseases, Tetraspanins, Endocrinology, Diabetes and Metabolism, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Child, geography.geographical_feature_category, biology, Glutamate Decarboxylase, Middle Aged, Islet, Organ Specificity, Child, Preschool, 030220 oncology & carcinogenesis, Female, Antibody, Adult, China, endocrine system, Adolescent, Nerve Tissue Proteins, 030209 endocrinology & metabolism, Zinc Transporter 8, Islets of Langerhans, Young Adult, 03 medical and health sciences, Antigen, GTP-Binding Proteins, Thyroid peroxidase, medicine, Humans, Protein Glutamine gamma Glutamyltransferase 2, Insulinoma, Aged, Autoantibodies, Type 1 diabetes, geography, Transglutaminases, business.industry, Autoantibody, Infant, medicine.disease, Diabetes Mellitus, Type 1, chemistry, Case-Control Studies, Immunology, biology.protein, Steroid 21-Hydroxylase, Glycated hemoglobin, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b253f1fd9d241545ff2a1d6359587f6Test
https://doi.org/10.1507/endocrj.ej20-0002Test

6

Association of cell free mitochondrial DNA and caspase-1 expression with disease severity and ARTs efficacy in HIV infection

المؤلفون: Ibrar Ahmed, Iram Shahzadi, Shahid Waseem, Sidra Bukhari, Mariam Anees, Riffat Aysha Anis, Zain Ali

المصدر: Molecular Biology Reports. 48:3327-3336

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4defc058207e2d298d8f8a054d0fe89Test
https://doi.org/10.1007/s11033-021-06313-0Test

7

Human leukocyte antigen I is significantly downregulated in patients with myxoid liposarcomas

المؤلفون: Masanori Hayashi, Tetsuro Yamagishi, Chihaya Imai, Hajime Umezu, Takashi Ariizumi, Yudai Murayama, Akira Ogose, Naoki Oike, Hiroyuki Kawashima, Hiroshi Hatano, Naoto Endo

المصدر: Cancer Immunology, Immunotherapy

مصطلحات موضوعية: Male, Cancer Research, Pathology, medicine.medical_treatment, Liposarcomas, B7-H1 Antigen, 0302 clinical medicine, HLA Antigens, Tumor Microenvironment, Immunology and Allergy, Programmed death ligand 1, Aged, 80 and over, 0303 health sciences, Middle Aged, Prognosis, Immunohistochemistry, Liposarcoma, Myxoid, Progression-Free Survival, Oncology, 030220 oncology & carcinogenesis, Original Article, Female, Human leukocyte antigen I, Adult, medicine.medical_specialty, Adolescent, Tumor immune microenvironment, Immunology, Down-Regulation, Human leukocyte antigen, Liposarcoma, Pleomorphic Liposarcoma, 03 medical and health sciences, Young Adult, Lymphocytes, Tumor-Infiltrating, medicine, Humans, neoplasms, 030304 developmental biology, Aged, Myxoid liposarcoma, Tumor-infiltrating lymphocytes, business.industry, Macrophages, Histocompatibility Antigens Class I, Immunotherapy, medicine.disease, body regions, CD163+ macrophages, business, CD163

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80679c1ba2c44a0ce4ca344ffcd402aeTest
http://europepmc.org/articles/PMC8571150Test

8

Reduced frequency of T helper 17 and T helper 1 cells and their association with critical coronavirus disease 2019

المؤلفون: Mohammad Mirzakhani, Zahra Moulana, Mousa Mohammadnia-Afrouzi, Hamed Mehdinezhad, Mohammad Jafari, Mehdi Shahbazi, Reza Ghadimi, Mostafa Ghasemzadeh, Mahmoud Sadeghi-Haddad-Zavareh, Mojgan Bagherzadeh, Mahdi Sepidarkish, Ali Shokuhi Rad, Mostafa Javanian, Masomeh Bayani, Maryam Rezanejad

المصدر: Apmis

مصطلحات موضوعية: Male, 0301 basic medicine, Cellular immunity, T helper 1, Cell, Severity of Illness Index, T-Lymphocytes, Regulatory, 0302 clinical medicine, Immunology and Allergy, Interferon gamma, Young adult, Aged, 80 and over, Coronavirus disease 2019, medicine.diagnostic_test, Interleukin-17, hemic and immune systems, General Medicine, Middle Aged, Flow Cytometry, Treg, medicine.anatomical_structure, T helper 17, 030220 oncology & carcinogenesis, Original Article, Female, medicine.drug, Adult, Microbiology (medical), Adolescent, Coronavirus disease 2019 (COVID-19), Critical Illness, chemical and pharmacologic phenomena, Pathology and Forensic Medicine, Flow cytometry, Interferon-gamma, Young Adult, 03 medical and health sciences, Immune system, Severity of illness, medicine, Humans, Aged, SARS-CoV-2, business.industry, COVID-19, Original Articles, Th1 Cells, CD4 Lymphocyte Count, 030104 developmental biology, Immunology, Th17 Cells, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a8abdc7016e07f95134b2a67047d858Test
https://doi.org/10.1111/apm.13129Test

9

First-line treatment of advanced/metastatic melanoma with anti-PD-1 antibodies: multicenter experience in Poland

المصدر: Immunotherapy. 13:297-307

مصطلحات موضوعية: Adult, Male, Oncology, medicine.medical_specialty, Multivariate analysis, Drug-Related Side Effects and Adverse Reactions, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Immunology, Pembrolizumab, Antibodies, Monoclonal, Humanized, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Humans, Immunology and Allergy, Medicine, 030212 general & internal medicine, Stage (cooking), Adverse effect, Immune Checkpoint Inhibitors, Melanoma, Aged, Retrospective Studies, Aged, 80 and over, business.industry, Immunotherapy, Middle Aged, Prognosis, medicine.disease, Progression-Free Survival, Survival Rate, Clinical trial, Nivolumab, Treatment Outcome, 030220 oncology & carcinogenesis, Female, Poland, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75481f1f9c5cc0cca549a49f8bad084dTest
https://doi.org/10.2217/imt-2020-0217Test

10

Patients with autoimmune polyendocrine syndrome type 1 have an increased susceptibility to severe herpesvirus infections

المؤلفون: Iivari Kleino, Saila Laakso, Hannamari Välimaa, Outi Mäkitie, T. Petteri Arstila, Iivo Hetemäki, Eliisa Kekäläinen

المساهمون: Department of Bacteriology and Immunology, TRIMM - Translational Immunology Research Program, Research Programs Unit, Clinicum, HUS Children and Adolescents, Medicum, Children's Hospital, Department of Virology, HUSLAB, Oral and Maxillofacial Surgery, Helsinki University Hospital Area, Lastentautien yksikkö, Petteri Arstila / Principal Investigator

المصدر: Clinical Immunology (Orlando, Fla.)

مصطلحات موضوعية: Male, Herpesvirus 3, Human, Herpes zoster, CHRONIC MUCOCUTANEOUS CANDIDIASIS, medicine.disease_cause, Cohort Studies, APS-1, autoimmune polyendocrine syndrome type 1, Varicella zoster, 0302 clinical medicine, Autoantibody, Interferon, Risk Factors, Immunology and Allergy, Medicine, Chronic mucocutaneous candidiasis, Child, Polyendocrinopathies, Autoimmune, Immunodeficiency, 0303 health sciences, Immunity, Cellular, biology, Middle Aged, 3. Good health, 030220 oncology & carcinogenesis, Female, Antibody, medicine.drug, Adult, Herpes simplex, Adolescent, Immunology, VZV, varicella zoster virus, 03 medical and health sciences, Young Adult, Immune system, AIRE, Full Length Article, Humans, IFN, interferon, Type I interferon, 030304 developmental biology, Aged, business.industry, Varicella zoster virus, Interferon-alpha, VARICELLA, medicine.disease, PREVENTION, Autoimmune polyendocrine syndrome type 1, Varicella Zoster Virus Infection, biology.protein, HSV, herpes simplex virus, AUTOANTIBODIES, 3111 Biomedicine, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff03828487759ffed1d4a83e19796b0fTest
http://hdl.handle.net/10138/336743Test

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