نتائج البحث

1

Elevated angiotensin II induces platelet apoptosis through promoting oxidative stress in an AT1R‐dependent manner during sepsis

المؤلفون: Dun-Feng Xu, Yu-Jian Liu, Chu-Fan Xu, Yan Wang, Yan-Fei Mao, Lai Jiang, Xiao-Yan Zhu

المصدر: Journal of Cellular and Molecular Medicine

مصطلحات موضوعية: Male, 0301 basic medicine, thrombocytopenia, Apoptosis, Pharmacology, medicine.disease_cause, Mice, 0302 clinical medicine, Platelet, Cells, Cultured, platelet, Aged, 80 and over, chemistry.chemical_classification, Angiotensin II, Middle Aged, Prognosis, Losartan, 030220 oncology & carcinogenesis, Molecular Medicine, Original Article, Female, Signal Transduction, medicine.drug, Adult, Blood Platelets, reactive oxygen species (ROS), Receptor, Angiotensin, Type 1, Sepsis, 03 medical and health sciences, medicine, Animals, Humans, angiotensin II (Ang II), Aged, Cell Proliferation, Reactive oxygen species, Intrinsic apoptosis, angiotensin II receptor blocker (ARB), Original Articles, Cell Biology, medicine.disease, Oxidative Stress, 030104 developmental biology, Gene Expression Regulation, chemistry, Case-Control Studies, Reactive Oxygen Species, Angiotensin II Type 1 Receptor Blockers, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6123010f834858f85232068229ee63deTest
https://doi.org/10.1111/jcmm.16382Test

2

NRP1 and MMP9 are dual targets of RNA‐binding protein QKI5 to alter VEGF‐R/ NRP1 signalling in trophoblasts in preeclampsia

المؤلفون: Xingyu Yang, Biwei He, Dan Chen, Weiwei Cheng

المصدر: Journal of Cellular and Molecular Medicine

مصطلحات موضوعية: 0301 basic medicine, Adult, medicine.medical_treatment, MMP9, preeclampsia, 03 medical and health sciences, Mice, 0302 clinical medicine, Pre-Eclampsia, In vivo, Cell Movement, Pregnancy, Neuropilin 1, medicine, NRP1, QKI5, Animals, Humans, Secretion, Cell Proliferation, Cell growth, Chemistry, Growth factor, Trophoblast, RNA-Binding Proteins, Cell Biology, Original Articles, trophoblast, Hedgehog signaling pathway, Neuropilin-1, Cell biology, Trophoblasts, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Receptors, Vascular Endothelial Growth Factor, Matrix Metalloproteinase 9, 030220 oncology & carcinogenesis, Case-Control Studies, Molecular Medicine, Original Article, Female, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4918015cab186bc5d21a6f1f0b02e93Test
http://europepmc.org/articles/PMC8184681Test

3

GLS1-mediated glutaminolysis unbridled by MALT1 protease promotes psoriasis pathogenesis

المؤلفون: Peng Li, Leqing Zhu, Liehua Deng, Zhizhong Li, Hua Zhang, Yueqi Song, Xichun Xia, Jianlei Hao, Xiao Wang, Chengbin Guo, Zhinan Yin, Guangchao Cao, Yixia Tian, Wei Zhou, Yunfei Gao, Jingxiang Zhong, Guodong Sun

المصدر: J Clin Invest

مصطلحات موضوعية: Adult, Keratinocytes, Male, 0301 basic medicine, Chemokine, Glutamine, Cellular differentiation, medicine.disease_cause, Autoimmunity, Mice, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Glutaminase, T-Lymphocyte Subsets, Psoriasis, medicine, Animals, Humans, RNA, Messenger, Histone H3 acetylation, Aged, Mice, Knockout, Glutaminolysis, biology, Chemistry, Interleukin-17, Cell Differentiation, General Medicine, Middle Aged, medicine.disease, Mice, Inbred C57BL, Disease Models, Animal, MALT1, 030104 developmental biology, Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein, Case-Control Studies, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Th17 Cells, Female, IL17A, Metabolic Networks and Pathways, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f6d904955d64d82e287033ac565778Test
https://doi.org/10.1172/jci129269Test

4

Sirt1 activation negatively regulates overt apoptosis in Mtb-infected macrophage through Bax

المؤلفون: Hong Yang, Baoxue Ge, Yanghaoyu Chen, Jianxia Chen, Yan Jiang, Ling Hong

المصدر: International immunopharmacology. 91

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Tuberculosis, Mice, 129 Strain, endocrine system diseases, Immunology, Regulator, Apoptosis, Resveratrol, Biology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Sirtuin 1, medicine, Immunology and Allergy, Animals, Humans, Cells, Cultured, bcl-2-Associated X Protein, Pharmacology, Mice, Knockout, Messenger RNA, Activator (genetics), Macrophages, food and beverages, Mycobacterium tuberculosis, medicine.disease, biology.organism_classification, Enzyme Activation, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Case-Control Studies, Host-Pathogen Interactions, Cancer research, Female, Mouse Macrophage, hormones, hormone substitutes, and hormone antagonists, Mycobacterium, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15abd98dd4d1d7e43d3cf7c96bf788acTest
https://pubmed.ncbi.nlm.nih.gov/33373810Test

5

Myeloid-Derived Growth Factor Promotes Intestinal Glucagon-Like Peptide-1 Production in Male Mice With Type 2 Diabetes

المؤلفون: Lin Xiang, Guangda Xiang, Junxia Zhang, Min Liu, Bei Guo, Li Wang, Biao Zhu, Huan Li, Lingwei Xiang, Yan Ding, Biying Meng, Hui Zhao, Jing Dong, Yixiang Li, Jiajia Zhang

المصدر: Endocrinology. 161

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84d29536c48c610cf8c4b77f12a0559dTest
https://doi.org/10.1210/endocr/bqaa003Test

6

Fibroblast Growth Factor (FGF) Signaling Protects Against Acute Pancreatitis-Induced Damage by Modulating Inflammatory Responses

المؤلفون: Cheng-Fei Zhao, Yu-Cai Jiang, Hai-Jian Tu, Wei Lin, Zhi-Wei Chen

المصدر: Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Inflammation, 030204 cardiovascular system & hematology, Fibroblast growth factor, Dinoprostone, Pathogenesis, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, NF-KappaB Inhibitor alpha, Lab/In Vitro Research, Internal medicine, Nitriles, medicine, Animals, Humans, Amylase, Sulfones, Lipase, biology, Chemistry, Pancreatitis, Acute Necrotizing, Tumor Necrosis Factor-alpha, General Medicine, FGF1, Middle Aged, medicine.disease, Rats, Endocrinology, C-Reactive Protein, Pancreatitis, 030220 oncology & carcinogenesis, Case-Control Studies, Acute Disease, Amylases, biology.protein, Acute pancreatitis, Fibroblast Growth Factor 1, Fibroblast Growth Factor 2, Female, medicine.symptom, Signal transduction, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08457b0eb72c749efd8287c4e48b60baTest
http://europepmc.org/articles/PMC7171432Test

7

Promotion of Calcium/Calmodulin-Dependent Protein Kinase 4 by GLUT1-Dependent Glycolysis in Systemic Lupus Erythematosus

المؤلفون: Mami Tamai, Shimpei Morimoto, Kunihiro Ichinose, Remi Sumiyoshi, Shin-ya Kawashiri, Shoichi Fukui, Naoki Iwamoto, Masataka Umeda, Tomohiro Koga, Tomohito Sato, Yushiro Endo, Tomoki Origuchi, Atsushi Kawakami, Hideki Nakamura, Kaori Furukawa

المصدر: Arthritisrheumatology (Hoboken, N.J.). 71(5)

مصطلحات موضوعية: 0301 basic medicine, CD4-Positive T-Lymphocytes, Male, Benzylamines, Mice, Inbred MRL lpr, Cellular differentiation, Pentose Phosphate Pathway, Mice, 0302 clinical medicine, Pyruvic Acid, Fructosediphosphates, Immunology and Allergy, Lupus Erythematosus, Systemic, Glycolysis, Glucose Transporter Type 1, Sulfonamides, medicine.diagnostic_test, Chemistry, Interleukin-17, Fructosephosphates, CD28, Cell Differentiation, Middle Aged, Real-time polymerase chain reaction, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Metabolome, Female, Adult, medicine.medical_specialty, T cell, Immunology, Glucose-6-Phosphate, Flow cytometry, 03 medical and health sciences, Rheumatology, Internal medicine, medicine, Animals, Humans, Metabolomics, Lactic Acid, Protein kinase A, Protein Kinase Inhibitors, Lupus erythematosus, medicine.disease, 030104 developmental biology, Endocrinology, Case-Control Studies, Th17 Cells, Immunologic Memory, Calcium-Calmodulin-Dependent Protein Kinase Type 4

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::055ee1c40996b130806c31720de035a9Test
https://pubmed.ncbi.nlm.nih.gov/30462889Test

8

p66Shc deficiency enhances CXCR4 and CCR7 recycling in CLL B cells by facilitating their dephosphorylation-dependent release from β-arrestin at early endosomes

المؤلفون: Nagaja Capitani, Veronica Martini, Andrea Visentin, Gianpietro Semenzato, Pier Giuseppe Pelicci, Mario Milco D'Elios, Livio Trentin, Francesca Cattaneo, Noemi Manganaro, Federica Frezzato, Alessandra Gamberucci, Cosima T. Baldari, Laura Patrussi

المصدر: Oncogene. 37(11)

مصطلحات موضوعية: 0301 basic medicine, Adult, Cancer Research, Chemokine, Receptors, CCR7, Receptors, CXCR4, Src Homology 2 Domain-Containing, Transforming Protein 1, Endosome, Chronic lymphocytic leukemia, C-C chemokine receptor type 7, Endosomes, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Piperidines, immune system diseases, hemic and lymphatic diseases, Genetics, medicine, Bruton's tyrosine kinase, Animals, Humans, Phosphorylation, Molecular Biology, Cells, Cultured, Germ-Line Mutation, beta-Arrestins, Mice, Knockout, biology, Adenine, Chemotaxis, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, 030104 developmental biology, Pyrimidines, chemistry, 030220 oncology & carcinogenesis, Ibrutinib, Case-Control Studies, Proteolysis, biology.protein, Cancer research, Neoplastic cell, Pyrazoles

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b206305091439b65468bd01cd0a4bf6bTest
https://pubmed.ncbi.nlm.nih.gov/29326436Test

9

Pivotal role of matrix metalloproteinase 13 in extracellular matrix turnover in idiopathic pulmonary fibrosis

المؤلفون: Takayuki Shiomi, Yasunori Okada, Clemens Ruppert, Werner Seeger, Andreas Günther, György Lang, Jeanine D'Armiento, Takwi Nkyimbeng, Bhola K. Dahal

المصدر: PLoS ONE, Vol 8, Iss 9, p e73279 (2013)
PLoS ONE

مصطلحات موضوعية: Pathology, lcsh:Medicine, Matrix metalloproteinase, Extracellular matrix, Mice, chemistry.chemical_compound, Idiopathic pulmonary fibrosis, 0302 clinical medicine, Fibrosis, Pulmonary fibrosis, lcsh:Science, Lung, 0303 health sciences, Multidisciplinary, Tissue Inhibitor of Metalloproteinases, Middle Aged, respiratory system, Tissue Donors, Extracellular Matrix, Up-Regulation, 3. Good health, Hydroxyproline, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Collagen, Matrix Metalloproteinase 1, medicine.symptom, Research Article, Adult, medicine.medical_specialty, Inflammation, Bleomycin, 03 medical and health sciences, Matrix Metalloproteinase 13, medicine, Animals, Humans, 030304 developmental biology, business.industry, lcsh:R, medicine.disease, Idiopathic Pulmonary Fibrosis, respiratory tract diseases, chemistry, Case-Control Studies, Proteolysis, lcsh:Q, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa39d7bd70c09ca52ff89d14f940de25Test
http://europepmc.org/articles/PMC3759404?pdf=renderTest

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