Interleaved water and fat MR thermometry for monitoring high intensity focused ultrasound ablation of bone lesions
| العنوان: | Interleaved water and fat MR thermometry for monitoring high intensity focused ultrasound ablation of bone lesions |
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| المؤلفون: | Beatrice Lena, Max A. Viergever, Cyril J. Ferrer, Chrit T. W. Moonen, Clemens Bos, Lambertus W. Bartels |
| المصدر: | Magnetic Resonance in Medicine |
| بيانات النشر: | John Wiley and Sons Inc., 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Materials science, Swine, medicine.medical_treatment, Adipose tissue, Thermometry, VFA, Temperature measurement, bone, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Flip angle, In vivo, medicine, Technical Note, Animals, Humans, Radiology, Nuclear Medicine and imaging, MR thermometry, Technical Notes—Imaging Methodology, Temperature, Water, Ablation, Magnetic Resonance Imaging, High-intensity focused ultrasound, PRFS, medicine.anatomical_structure, high‐intensity focused ultrasound, Temporal resolution, High-Intensity Focused Ultrasound Ablation, Bone marrow, interleaved MRI, 030217 neurology & neurosurgery, Biomedical engineering |
| الوصف: | PURPOSE To demonstrate that interleaved MR thermometry can monitor temperature in water and fat with adequate temporal resolution. This is relevant for high intensity focused uUltrasounds (HIFU) treatment of bone lesions, which are often found near aqueous tissues, as muscle, or embedded in adipose tissues, as subcutaneous fat and bone marrow. METHODS Proton resonance frequency shift (PRFS)-based thermometry scans and T1 -based 2D variable flip angle (2D-VFA) thermometry scans were acquired alternatingly over time. Temperature in water was monitored using PRFS thermometry, and in fat by 2D-VFA thermometry with slice profile effect correction. The feasibility of interleaved water/fat temperature monitoring was studied ex vivo in porcine bone during MR-HIFU sonication. Precision and stability of measurements in vivo were evaluated in a healthy volunteer under non-heating conditions. RESULTS The method allowed observing temperature change over time in muscle and fat, including bone marrow, during MR-HIFU sonication, with a temporal resolution of 6.1 s. In vivo, the apparent temperature change was stable on the time scale of the experiment: In 7 min the systematic drift was |
| اللغة: | English |
| تدمد: | 1522-2594 0740-3194 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e29386ff147b62585de0e2f00c6a7931Test http://europepmc.org/articles/PMC8596687Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....e29386ff147b62585de0e2f00c6a7931 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15222594 07403194 |
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