المؤلفون: Markus Zweckstetter, King Faisal Yambire, Niels Denkert, Claudia Steinem, Nelli Teske, Daryna Tarasenko, Michael Meinecke, Ira Milosevic, Indrani Mukherjee, Garima Jaipuria, Benjamin Kroppen

المصدر: Cellular and Molecular Life Sciences
Cellular and molecular life sciences 78(5), 2355-2370 (2021). doi:10.1007/s00018-020-03647-z

مصطلحات موضوعية: Phosphatidylinositol 4,5-Diphosphate, ENTH domain, Epsin, Reconstitution of membrane dynamics, 0302 clinical medicine, epsin, metabolism [Phosphatidylinositol 4,5-Diphosphate], 0303 health sciences, Chemistry, ultrastructure [Cell Membrane], metabolism [Clathrin], metabolism [Membrane Lipids], Endocytosis, Clathrin-mediated endocytosis, genetics [Membrane Proteins], Protein Transport, Membrane, Membrane curvature, Molecular Medicine, Original Article, genetics [Adaptor Proteins, Vesicular Transport], metabolism [Adaptor Proteins, Vesicular Transport], Protein Binding, genetics [Binding Sites], chemistry [Cell Membrane], metabolism [Cell Membrane], Protein–protein interaction, Membrane Lipids, 03 medical and health sciences, Cellular and Molecular Neuroscience, Protein Domains, chemistry [Adaptor Proteins, Vesicular Transport], Humans, chemistry [Membrane Proteins], ddc:610, Membrane dynamics, Molecular Biology, 030304 developmental biology, Pharmacology, Binding Sites, Cell Membrane, Membrane Proteins, Cell Biology, Receptor-mediated endocytosis, chemistry [Membrane Lipids], Clathrin, Microscopy, Electron, Adaptor Proteins, Vesicular Transport, Membrane protein, Mutation, Biophysics, metabolism [Membrane Proteins], 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::299604b0231580d1487db82e8f61580bTest
https://doi.org/10.1007/s00018-020-03647-zTest

المؤلفون: Bernd Knöll, Renate Lüllmann-Rauch, Paul Saftig, Christian Haass, Yasuo Uchiyama, Wolfgang Wurst, Renate Wanner, Anja Capell, Rudi D'Hooge, Georg Werner, Stijn Stroobants, Patrick Lüningschrör, Benedikt Wefers, Daniela Sinske, Soichiro Kakuta, Michael Sendtner, Benjamin Dombert, Markus Damme

المصدر: Cell Reports, Vol 30, Iss 10, Pp 3506-3519.e6 (2020)
Cell reports 30(10), 3506-3519.e6 (2020). doi:10.1016/j.celrep.2020.02.060

مصطلحات موضوعية: 0301 basic medicine, MODIFIER, Vacuole, pathology [Facial Nerve], VARIANTS, Axonal Transport, metabolism [Lysosomes], 0302 clinical medicine, innervation [Muscles], Risk Factors, Axon, lcsh:QH301-705.5, genetics [Nerve Tissue Proteins], Mice, Knockout, Motor Neurons, DEMENTIA, Muscles, ultrastructure [Autophagosomes], ultrastructure [Axon Initial Segment], Frontotemporal lobar degeneration, metabolism [Autophagosomes], Cell biology, genetics [Membrane Proteins], Facial Nerve, medicine.anatomical_structure, genetics [Frontotemporal Lobar Degeneration], Life Sciences & Biomedicine, PROTEINS, Nerve Tissue Proteins, ultrastructure [Motor Neurons], Biology, General Biochemistry, Genetics and Molecular Biology, MECHANISMS, Lipofuscin, 03 medical and health sciences, pathology [Brain Stem], MOTILITY, Lysosome, Organelle, medicine, Animals, Genetic Predisposition to Disease, ddc:610, metabolism [Cell Nucleus], PROGRANULIN, deficiency [Membrane Proteins], Axon Initial Segment, Cell Nucleus, FRONTOTEMPORAL LOBAR DEGENERATION, Science & Technology, deficiency [Nerve Tissue Proteins], MUTATIONS, Autophagosomes, metabolism [Axon Initial Segment], Membrane Proteins, ultrastructure [Lysosomes], metabolism [Motor Neurons], Cell Biology, medicine.disease, Axon initial segment, Mice, Inbred C57BL, 030104 developmental biology, nervous system, lcsh:Biology (General), Axoplasmic transport, Frontotemporal Lobar Degeneration, Lysosomes, 030217 neurology & neurosurgery, Brain Stem

وصف الملف: Print

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eaa4dcd1581611e9ae6d198c56b849fTest
http://www.sciencedirect.com/science/article/pii/S221112472030228XTest

المؤلفون: Galina Apostolova, Isabella Cera, Patrick Feurle, Andre Fischer, Georg Dechant, Derek W. Morris, Andreas Abentung, Aodán Laighneach, Nico Wahl, Simon Sprenger, Michael Bucher, Eduard Stefan, Laura Whitton, David Teis, Cornelia Ablinger

المصدر: The EMBO journal 40(3), e103701 (2021). doi:10.15252/embj.2019103701
The EMBO Journal

مصطلحات موضوعية: Scaffold protein, Male, Cell Plasticity, human cognitive ability, metabolism [Endosomal Sorting Complexes Required for Transport], metabolism [Hippocampus], chemistry [Nuclear Proteins], Hippocampus, Chromatin, Epigenetics, Genomics & Functional Genomics, neuronal activity, Mice, 0302 clinical medicine, Cognition, Gene expression, Premovement neuronal activity, Gene Regulatory Networks, genetics [Schizophrenia], metabolism [Transcription Factors], Membrane & Intracellular Transport, metabolism [Nuclear Envelope], Cells, Cultured, Neurons, 0303 health sciences, General Neuroscience, chemistry [Transcription Factors], genetics [Matrix Attachment Region Binding Proteins], Nuclear Proteins, genetics [Nuclear Proteins], Articles, nuclear envelope, genetics [Transcription Factors], metabolism [Intellectual Disability], Chromatin, genetics [Membrane Proteins], Schizophrenia, metabolism [Neurons], metabolism [Schizophrenia], metabolism [Nuclear Proteins], Vacuolar Proton-Translocating ATPases, Nuclear Envelope, Biology, Article, General Biochemistry, Genetics and Molecular Biology, metabolism [Vacuolar Proton-Translocating ATPases], chemistry [Matrix Attachment Region Binding Proteins], 03 medical and health sciences, SATB2, Intellectual Disability, ddc:570, medicine, Inner membrane, Animals, Humans, chemistry [Membrane Proteins], metabolism [Cell Nucleus], Molecular Biology, Gene, 030304 developmental biology, Cell Nucleus, Endosomal Sorting Complexes Required for Transport, General Immunology and Microbiology, Mechanism (biology), Membrane Proteins, Matrix Attachment Region Binding Proteins, medicine.disease, cytology [Hippocampus], metabolism [Matrix Attachment Region Binding Proteins], Mutation, cytology [Neurons], ATPases Associated with Diverse Cellular Activities, chromatin, genetics [Intellectual Disability], metabolism [ATPases Associated with Diverse Cellular Activities], Neuroscience, 030217 neurology & neurosurgery, metabolism [Membrane Proteins], Transcription Factors, HeLa Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd6c12f384e7aa85602f7c65d2d82289Test
https://pub.dzne.de/record/155832Test

المؤلفون: Pietro Tiraboschi, Katrina M. Moore, Nick C. Fox, David L. Thomas, Jonathan D. Rohrer, Begoña Indakoetxea, Serge Gauthier, Thomas E. Cope, Mikel TaintaMD, Enrico Premi, Philip Vandamme, Giorgio Giaccone, Mircea Balasa, Sandra E. Black, John C. van Swieten, Catharina Prix, Sergi Borrego-Écija, Sandro Sorbi, Håkan Thonberg, Roser Sala-Llonch, Rick van Minkelen, Maria de Arriba, Elizabeth Finger, Michele Veldsman, Raquel Sánchez-Valle, Vesna Jelic, Veronica Redaelli, Zigor Diaz, James B. Rowe, Daniela Galimberti, Rhian S Convery, Anna Antonell, Miren Zulaica, Jennifer M. Nicholas, Alessandro Padovani, Diana Duro, Giuseppe Di Fede, Albert Lladó, Núria Bargalló, Pedro Rosa-Neto, Sara Prioni, Alazne Gabilondo, C. Ferreira, Andrea Arighi, Sara Mitchell, Mario Masellis, Chiara Fenoglio, Rachelle Shafei, Benjamin Bender, Rik Vandenberghe, Isabel Santana, Carlo Wilke, Christen Shoesmith, Janne M. Papma, Mathieu Vandenbulcke, Robart Bartha, Sandra V. Loosli, Giorgio Fumagalli, Ana Verdelho, Robert Laforce, Paola Caroppo, Adrian Danek, Jessica L. Panman, Maria Rosário Almeida, Carolin Heller, Jorge Villanua, Johannes Levin, Rita Guerreiro, Stefano Gazzina, Jose Bras, Miguel Castelo-Branco, Ekaterina Rogaeva, Fabrizio Tagliavini, Giacomina Rossi, Markus Otto, Timothy Rittman, Beatriz Santiago, Simon Mead, Rosa Rademakers, Maria João Leitão, Simon Ducharme, Sarah Anderl-Straub, Ron Keren, Ione O.C. Woollacott, Morris Freedman, Gabriel Miltenberger, Fermin Moreno, Martin N. Rossor, Tobias Hoegen, Jaume Olives, Carolyn Timberlake, Barbara Borroni, Ricardo Taipa, Elio Scarpini, David M. Cash, Miguel Tábuas-Pereira, Roberto Gasparotti, Sonja Schönecker, Martina Bocchetta, Lieke H.H. Meeter, Alexander Gerhard, Rose Bruffaerts, Carmela Tartaglia, Caroline V. Greaves, Christopher C Butler, Toby Flanagan, Sónia Afonso, Matthis Synofzik, Linn Öijerstedt, David F. Tang-Wai, Yolande A.L. Pijnenburg, Maura Cosseddu, Carolina Maruta, Alexandre de Mendonça, Christin Andersson, Caroline Graff, Ana Gorostidi, Silvana Archetti, Giovanni B. Frisoni, Elisabeth Wlasich, Mollie Neason, Elisa Semler

المساهمون: Neurology, Amsterdam Neuroscience - Neurodegeneration, Clinical Psychology, Clinical Genetics, Repositório da Universidade de Lisboa, Rowe, James [0000-0001-7216-8679], Apollo - University of Cambridge Repository

المصدر: NeuroImage: Clinical, 29:102540. Elsevier BV
NeuroImage: Clinical, 29:102540. Elsevier
NeuroImage: Clinical 29, 102540-(2021). doi:10.1016/j.nicl.2020.102540
Medical Biophysics Publications
NeuroImage : Clinical
Borrego-Écija, S, Sala-Llonch, R, van Swieten, J, Borroni, B, Moreno, F, Masellis, M, Tartaglia, C, Graff, C, Galimberti, D, Laforce, R, Rowe, J B, Finger, E, Vandenberghe, R, Tagliavini, F, de Mendonça, A, Santana, I, Synofzik, M, Ducharme, S, Levin, J, Danek, A, Gerhard, A, Otto, M, Butler, C, Frisoni, G, Sorbi, S, Heller, C, Bocchetta, M, Cash, D M, Convery, R S, Moore, K M, Rohrer, J D, Sanchez-Valle, R, Rossor, M N, Fox, N C, Woollacott, I O C, Shafei, R, Greaves, C, Neason, M, Guerreiro, R, Bras, J, Thomas, D L, Nicholas, J, Mead, S, Meeter, L, Panman, J, Papma, J, van Minkelen, R, Pijnenburg, Y, Indakoetxea, B, Gabilondo, A, TaintaMD, M, de Arriba, M, Gorostidi, A, Zulaica, M, Villanua, J, Diaz, Z, Olives, J, Lladó, A, Balasa, M, Antonell, A, Bargallo, N, Premi, E, Cosseddu, M, Gazzina, S, Padovani, A, Gasparotti, R, Archetti, S, Black, S, Mitchell, S, Rogaeva, E, Freedman, M, Keren, R, Tang-Wai, D, Öijerstedt, L, Andersson, C, Jelic, V, Thonberg, H, Arighi, A, Fenoglio, C, Scarpini MD, E, Fumagalli, G, Cope, T, Timberlake, C, Rittman, T, Shoesmith, C, Bartha, R, Rademakers, R, Wilke, C, Bender, B, Bruffaerts, R, Vandamme, P, Vandenbulcke, M, Maruta, C, Ferreira, C B, Miltenberger, G, Verdelho, A, Afonso, S N, Taipa, R, Caroppo, P, di Fede, G, Giaccone, G, Prioni, S, Redaelli, V, Rossi, G, Tiraboschi, P, Duro, D, Rosario Almeida, M, Castelo-Branco, M, João Leitão, M, Tabuas-Pereira, M, Santiago, B, Gauthier, S, Rosa-Neto, P, Veldsman, M, Flanagan, T, Prix, C, Hoegen, T, Wlasich, E, Loosli, S, Schonecker, S, Semler, E & Anderl-Straub, S 2021, ' Disease-related cortical thinning in presymptomatic granulin mutation carriers ', NeuroImage: Clinical, vol. 29, 102540 . https://doi.org/10.1016/j.nicl.2020.102540Test
NeuroImage: Clinical, Vol 29, Iss, Pp 102540-(2021)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

مصطلحات موضوعية: Oncology, Granulin, Disease, Gene mutation, lcsh:RC346-429, 0302 clinical medicine, Progranulins, Supramarginal gyrus, genetics [Frontotemporal Dementia], genetics [Nerve Tissue Proteins], Granulins, Temporal cortex, 05 social sciences, Regular Article, Cerebral Cortical Thinning, Genetic mutations, genetics [Membrane Proteins], Neurology, Frontotemporal Dementia, lcsh:R858-859.7, Life Sciences & Biomedicine, Frontotemporal dementia, GRN, medicine.medical_specialty, Heterozygote, Cognitive Neuroscience, Presymptomatic, Neuroimaging, Nerve Tissue Proteins, genetics [Mutation], Genetic FTD Initiative GENFI, lcsh:Computer applications to medicine. Medical informatics, diagnostic imaging [Frontotemporal Dementia], 050105 experimental psychology, Cortical thickness, 03 medical and health sciences, Internal medicine, medicine, Humans, 0501 psychology and cognitive sciences, Radiology, Nuclear Medicine and imaging, ddc:610, lcsh:Neurology. Diseases of the nervous system, Science & Technology, business.industry, Membrane Proteins, medicine.disease, Mutation, Neurosciences & Neurology, Neurology (clinical), 1109 Neurosciences, business, Asymptomatic carrier, 030217 neurology & neurosurgery

وصف الملف: application/pdf; Print-Electronic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206c236cf6771818dba529a883b4673fTest
https://research.vumc.nl/en/publications/f32bfcad-31e0-49f2-b957-578f21195ea2Test

المؤلفون: Stefan F. Lichtenthaler, Paul Saftig, Tobias B. Huber, Lukas Heintz, Lisa Seipold, Lisa Schebsdat, Maja T. Lindenmeyer, Renate Lüllmann-Rauch, Sebastian Wetzel, Stephanie Zielinski, Oliver Kretz, Catherine Meyer-Schwesinger, Marlies Sachs, Wiebke Sachs, Julia Reichelt, Thorsten Wiech, Stephan A. Müller

المصدر: Journal of the American Society of Nephrology 32(6), 1389-1408 (2021). doi:10.1681/ASN.2020081213
J Am Soc Nephrol

مصطلحات موضوعية: 0301 basic medicine, Male, Proteomics, Nephrotic Syndrome, podocyte, physiology [Podocytes], ADAM10, glomerular disease, genetics [Amyloid Precursor Protein Secretases], Cell Communication, Podocyte, Blood Urea Nitrogen, ADAM10 Protein, genetics [ADAM10 Protein], Mice, 0302 clinical medicine, Glomerular Filtration Barrier, metabolism [Nephritis], Wnt Signaling Pathway, Cells, Cultured, pathology [Nephrotic Syndrome], Mice, Knockout, Nephritis, Chemistry, Cell adhesion molecule, Podocytes, metabolism [Podocytes], Wnt signaling pathway, pathology [Glomerular Filtration Barrier], General Medicine, Cadherins, adverse effects [Autoantibodies], metabolism [Nephrotic Syndrome], Cell biology, genetics [Membrane Proteins], medicine.anatomical_structure, Ectodomain, Nephrology, Creatinine, metabolism [ADAM10 Protein], Female, Proteases, metabolism [Cell Membrane], Adherens junction, 03 medical and health sciences, metabolism [Renal Insufficiency, Chronic], medicine, Cell Adhesion, Animals, Humans, ddc:610, Renal Insufficiency, Chronic, pathology [Podocytes], Autoantibodies, Cadherin, Cell Membrane, metabolism [Cadherins], Membrane Proteins, membranous nephropathy, metabolism [Amyloid Precursor Protein Secretases], Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Basic Research, Tissue Array Analysis, urine [Creatinine], pathology [Nephritis], Amyloid Precursor Protein Secretases, proteinuria, Transcriptome, physiopathology [Glomerular Filtration Barrier], 030217 neurology & neurosurgery, metabolism [Membrane Proteins]

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cd38702448fa14059c39567c6bc8975Test

المؤلفون: Atsushi Nambu, Makoto Sanbo, Xiumin Chen, Yuko Fukata, Harald Prüss, Hans-Christian Kornau, Hiroki Inahashi, Masumi Hirabayashi, Teppei Goto, Roger A. Nicoll, Yoko Hirano, Atsushi Yamagata, Satomi Chiken, Masaki Fukata, Shuya Fukai, Hiromi Sano

المصدر: Proceedings of the National Academy of Sciences of the United States of America 118(3), e2022580118-(2021). doi:10.1073/pnas.2022580118
Proceedings of the National Academy of Sciences of the United States of America

مصطلحات موضوعية: 0301 basic medicine, Hippocampus, metabolism [Hippocampus], genetics [ADAM Proteins], Synaptic Transmission, pathology [Epilepsy], Epilepsy, Mice, 0302 clinical medicine, Postsynaptic potential, pathology [Brain], Adam22 protein, mouse, Gene Knock-In Techniques, AMPA receptor, Neural Cell Adhesion Molecules, genetics [Nerve Tissue Proteins], Multidisciplinary, Intracellular Signaling Peptides and Proteins, Brain, Biological Sciences, genetics [Membrane Proteins], NMDA receptor, ddc:500, genetics [Receptors, AMPA], genetics [Calcium-Binding Proteins], genetics [Synaptic Transmission], Lgi1 protein, mouse, Guanylate kinase, genetics [Epilepsy], transsynaptic nanocolumn, Nerve Tissue Proteins, prevention & control [Epilepsy], Neurotransmission, Biology, LGI1–ADAM22, Receptors, N-Methyl-D-Aspartate, 03 medical and health sciences, genetics [Shaker Superfamily of Potassium Channels], genetics [Receptors, N-Methyl-D-Aspartate], medicine, Animals, Humans, genetics [Neural Cell Adhesion Molecules], Receptors, AMPA, LRRTM4 protein, mouse, ADAM22, Calcium-Binding Proteins, Membrane Proteins, MAGUK, medicine.disease, Disease Models, Animal, ADAM Proteins, 030104 developmental biology, pathology [Hippocampus], nervous system, metabolism [Brain], Shaker Superfamily of Potassium Channels, epilepsy, genetics [Intracellular Signaling Peptides and Proteins], Nrxn1 protein, mouse, Neuroscience, genetics [Guanylate Kinases], Guanylate Kinases, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68628950b12bc111c5ad4ecbb0ec6b28Test

المؤلفون: Florian Schubert, Till Huelnhagen, Susanne A. Schneider, Gudrun Schottmann, Jens Wuerfel, Antje Els, Bernd Ittermann, Petr Dusek, Thomas Klopstock, Julio Acosta-Cabronero, Ralf Mekle, Marcus Deschauer, Marta Skowrońska, Simon Robinson, Friedemann Paul, Vince I. Madai, Tomasz Kmieć, Thoralf Niendorf

المصدر: Movement disorders 35(1), 142-150 (2019). doi:10.1002/mds.27827

مصطلحات موضوعية: 0301 basic medicine, Pathology, medicine.medical_specialty, Iron, Caudate nucleus, genetics [Mutation], Gene mutation, Mitochondrial Proteins, White matter, 03 medical and health sciences, methods [Magnetic Resonance Imaging], 0302 clinical medicine, pathology [Brain], metabolism [Mitochondrial Membranes], Basal ganglia, medicine, Humans, ddc:610, metabolism [Iron], Chemistry, Putamen, Neurodegeneration, Brain, Membrane Proteins, Quantitative susceptibility mapping, metabolism [Mitochondria], medicine.disease, Magnetic Resonance Imaging, Mitochondria, genetics [Membrane Proteins], 030104 developmental biology, Globus pallidus, medicine.anatomical_structure, Neurology, metabolism [Brain], Cardiovascular and Metabolic Diseases, Mitochondrial Membranes, Mutation, genetics [Mitochondrial Proteins], Neurology (clinical), Technology Platforms, Function and Dysfunction of the Nervous System, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c71091ce9d5bc525f9c5191b49b19eTest
http://edoc.mdc-berlin.de/18430/1/18430oa.pdfTest

المؤلفون: Martin H. Schludi, Markus Damme, Wolfgang Wurst, Matthias Brendel, Dieter Edbauer, Katrin Fellerer, Anja Capell, Benedikt Wefers, Johannes Gnörich, Georg Werner, Christian Haass, Karin Wind

المصدر: EMBO reports 21(10), 19 (2020). doi:10.15252/embr.202050241
EMBO Reports
EMBO Rep. 21:e50241 (2020)

مصطلحات موضوعية: Pathology, medicine.medical_specialty, TDP-43, Nerve Tissue Proteins, Biology, Biochemistry, Article, 03 medical and health sciences, Mice, genetics [Progranulins], 0302 clinical medicine, Progranulins, Downregulation and upregulation, Ftd, Neurodegeneration, Progranulin, Tdp-43, Tmem106b, ddc:570, Gene expression, mental disorders, Genetics, medicine, progranulin, Animals, Humans, Molecular Biology of Disease, Molecular Biology, Gene knockout, Loss function, 030304 developmental biology, Mice, Knockout, 0303 health sciences, genetics [Intercellular Signaling Peptides and Proteins], neurodegeneration, Membrane Proteins, FTD, Frontotemporal lobar degeneration, Articles, medicine.disease, TDP‐43, genetics [Membrane Proteins], Proteostasis, TMEM106B, Intercellular Signaling Peptides and Proteins, genetics [Frontotemporal Lobar Degeneration], Frontotemporal Lobar Degeneration, Haploinsufficiency, Lysosomes, 030217 neurology & neurosurgery, Neuroscience

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df22da9d1bf1034c18000cc5bb17bb30Test
https://pub.dzne.de/record/154374Test

المؤلفون: Franz Hagn, Kai Schlepckow, Bettina Brunner, Harald Steiner, Andrea Steiner, Christian Haass

المصدر: The EMBO journal 39(20), e104247 (2020). doi:10.15252/embj.2019104247
The EMBO Journal

مصطلحات موضوعية: Protein Conformation, alpha-Helical, chemistry [Membrane Glycoproteins], Magnetic Resonance Spectroscopy, genetics [Amyloid Precursor Protein Secretases], genetics [Alzheimer Disease], metabolism [Microglia], 0302 clinical medicine, genetics [Membrane Glycoproteins], Membrane region, Structural Biology, Risk Factors, genetics [Adaptor Proteins, Signal Transducing], TREM2, genetics [Receptors, Immunologic], Receptors, Immunologic, Receptor, chemistry.chemical_classification, 0303 health sciences, Membrane Glycoproteins, General Neuroscience, Circular Dichroism, metabolism [Receptors, Immunologic], Articles, dynamics, Amino acid, ddc, Molecular Docking Simulation, Transmembrane domain, genetics [Membrane Proteins], Ectodomain, chemistry [Receptors, Immunologic], Microglia, metabolism [Alzheimer Disease], Signal Transduction, Intramembrane protease, Biology, Molecular Dynamics Simulation, Cleavage (embryo), genetics [Signal Transduction], General Biochemistry, Genetics and Molecular Biology, Article, metabolism [Cell Membrane], 03 medical and health sciences, metabolism [Adaptor Proteins, Signal Transducing], Protein Domains, Alzheimer Disease, ddc:570, Humans, chemistry [Membrane Proteins], structure, Molecular Biology, 030304 developmental biology, Adaptor Proteins, Signal Transducing, General Immunology and Microbiology, Cell Membrane, enzymology [Alzheimer Disease], Membrane Proteins, Post-translational Modifications, Proteolysis & Proteomics, chemistry [Adaptor Proteins, Signal Transducing], NMR, metabolism [Amyloid Precursor Protein Secretases], HEK293 Cells, chemistry, Mutation, biology.protein, Biophysics, Amyloid Precursor Protein Secretases, metabolism [Membrane Glycoproteins], 030217 neurology & neurosurgery, metabolism [Membrane Proteins], intramembrane protease, Neuroscience

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::336001d0982d8a4fa0349c4e2f1ac011Test

المؤلفون: Rachelle Shafei, Albert Lladó, Benjamin Bender, Luisa Benussi, Elisabeth Wlasich, Martha S. Foiani, Isabel Santana, Christen Shoesmith, Ione O.C. Woollacott, Nick C. Fox, David L. Thomas, Jonathan D. Rohrer, Pietro Tiraboschi, Mario Masellis, Sergi Borrego-Écija, Giorgio G. Fumagalli, Ron Keren, Sandro Sorbi, Rick van Minkelen, Vesna Jelic, Ekaterina Rogaeva, Mollie Neason, Enrico Premi, Timothy Rittman, Lieke H.H. Meeter, Giacomina Rossi, Veronica Redaelli, Roberta Ghidoni, Begoña Indakoetxea, Johannes Levin, Håkan Thonberg, Rhian S Convery, Henrik Zetterberg, Gemma Lombardi, Giuseppe Di Fede, Chiara Fenoglio, Jose Bras, Daniela Galimberti, Simon Mead, Miren Zulaica, David M. Cash, Gabriel Miltenberger, Markus Otto, Simon Ducharme, Myriam Barandiaran, Katrina M. Moore, Alessandro Padovani, Thomas E. Cope, Elizabeth Finger, Maria Carmela Tartaglia, Martin N. Rossor, M. Jorge Cardoso, Sara Mitchell, Rik Vandenberghe, Pedro Rosa-Neto, John C. van Swieten, Sarah Anderl-Straub, Maria Rosário Almeida, Zigor Diaz, Robart Bartha, Maria de Arriba, Caroline V. Greaves, Philip Vandamme, Giorgio Giaccone, Adrian Danek, Miguel Tábuas-Pereira, Carolina Maruta, Roberto Gasparotti, Jennifer M. Nicholas, Martina Bocchetta, Elisa Semler, Valentina Bessi, C. Ferreira, Robert Laforce, Sandra V. Loosli, Ana Verdelho, Paola Caroppo, Jaume Olives, Giuliano Binetti, Carolin Heller, Jorge Villanua, Stefano Gazzina, Amanda Heslegrave, Alazne Gabilondo, Sandra E. Black, Y.A.L. Pijnenburg, Mikel Tainta, Carolyn Timberlake, Sónia Afonso, Matthis Synofzik, Janne M. Papma, Sebastien Ourselin, Núria Bargalló, Barbara Borroni, Ricardo Taipa, Hans-Otto Karnarth, Camilla Ferrari, David F. Tang-Wai, Diana Duro, Catharina Prix, Serge Gauthier, Sara Prioni, Carlo Wilke, Michele Veldsman, Alexandre de Mendonça, Andrea Arighi, Christopher C Butler, Raquel Sánchez-Valle, Toby Flanagan, Carole H. Sudre, Jason D. Warren, Rita Guerreiro, Linn Öijerstedt, Beatriz Santiago, Rosa Rademakers, Miguel Castelo-Branco, Fabrizio Tagliavini, Maria João Leitão, Anna Antonell, Mathieu Vandenbulcke, Rose Bruffaerts, Jessica L. Panman, Alexander Gerhard, Tobias Hoegen, Ana Gorostidi, Silvana Archetti, James B. Rowe, Michela Pievani, Elio Scarpini, Giovanni B. Frisoni, Benedetta Nacmias, Sonja Schönecker, Maura Cosseddu, Christin Andersson, Caroline Graff, Morris Freedman, Fermin Moreno, Mircea Balasa, Lize C. Jiskoot

المساهمون: Sudre, Carole H [0000-0001-5753-428X], Apollo - University of Cambridge Repository, Rowe, James [0000-0001-7216-8679], Neurology

المصدر: NeuroImage : Clinical
NeuroImage: Clinical, Vol. 24 (2019) P. 102077
NeuroImage: Clinical, 24:102077. Elsevier
NeuroImage: Clinical 24, 102077-(2019). doi:10.1016/j.nicl.2019.102077
NeuroImage: Clinical, Vol 24, Iss, Pp-(2019)

مصطلحات موضوعية: Oncology, Male, SEGMENTATION, PROTEIN, physiopathology [Frontotemporal Dementia], DISEASE, 0302 clinical medicine, White matter hyperintensities, blood [Glial Fibrillary Acidic Protein], Longitudinal Studies, education.field_of_study, Regular Article, Neurology, Frontotemporal Dementia, Disease Progression, GRN, medicine.medical_specialty, lcsh:Computer applications to medicine. Medical informatics, MRI, Magnetic Resonance Imaging, White matter, 03 medical and health sciences, AGE, Humans, neurofilament protein L, education, Aged, CSF, Cerebrospinal fluid, Science & Technology, Trail Making Test, Frontotemporal dementia, Dementia, Progranulin, medicine.disease, POLYMORPHISM, Case-Control Studies, Asymptomatic Diseases, Mutation, Neurosciences & Neurology, Neurology (clinical), GENFI, 030217 neurology & neurosurgery, Executive dysfunction, blood [Frontotemporal Dementia], GFAP, Glial Fibrillary Acidic Protein, blood [Neurofilament Proteins], lcsh:RC346-429, genetics [Progranulins], Executive Function, Progranulins, pathology [Gray Matter], Neurofilament Proteins, BRAIN ATROPHY, GM, Grey Matter, Gray Matter, genetics [Frontotemporal Dementia], genetics [Nerve Tissue Proteins], 05 social sciences, Organ Size, Middle Aged, Magnetic Resonance Imaging, White Matter, genetics [Membrane Proteins], medicine.anatomical_structure, FTD, Frontotemporal dementia, GENFI, GENetic Frontotemporal dementia Initiative, lcsh:R858-859.7, Female, Life Sciences & Biomedicine, Adult, Heterozygote, Cognitive Neuroscience, Population, Prodromal Symptoms, Neuroimaging, PHENOTYPES, Nerve Tissue Proteins, MUTATION CARRIERS, WM, White Matter, Grey matter, diagnostic imaging [Frontotemporal Dementia], 050105 experimental psychology, diagnostic imaging [White Matter], Atrophy, TMEM106B protein, human, Internal medicine, mental disorders, Glial Fibrillary Acidic Protein, medicine, 0501 psychology and cognitive sciences, Radiology, Nuclear Medicine and imaging, ddc:610, lcsh:Neurology. Diseases of the nervous system, business.industry, GFAP protein, human, WMH, White Matter Hyperintensity, diagnostic imaging [Gray Matter], Membrane Proteins, Hyperintensity, GRN, Progranulin, TMEM106B, ddc:618.97, GRN protein, human, business

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الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afca27b8baf2e0e1c1a1dd3020431e43Test
http://europepmc.org/articles/PMC6911860Test