المؤلفون: Derek H. Oakley, Caitlin Commins, Matthew P. Frosch, Simon Dujardin, Mirra Chung, Bradley T. Hyman, Rachel E. Bennett, Naomi Klickstein

المصدر: The Journal of Neuroscience

مصطلحات موضوعية: Male, 0301 basic medicine, Programmed cell death, Cell Survival, Induced Pluripotent Stem Cells, PSEN1 L435F, tau Proteins, medicine.disease_cause, Mice, 03 medical and health sciences, 0302 clinical medicine, Alzheimer Disease, Neurobiology of Disease, neurotoxicity, mental disorders, MAPT, Presenilin-1, medicine, PSEN1, Animals, Humans, Induced pluripotent stem cell, Research Articles, Cells, Cultured, Aged, 80 and over, Mutation, iPSC, tau aggregation, Chemistry, General Neuroscience, Neurotoxicity, Alzheimer's disease, tau seeding, Middle Aged, medicine.disease, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Tauopathies, nervous system, Cell culture, Female, Neurotoxicity Syndromes, Neuron, FTLD, 030217 neurology & neurosurgery, Intracellular

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb21addd0ffb109091b3e2bb911d6459Test
https://doi.org/10.1523/jneurosci.2590-20.2021Test

المؤلفون: Caitlin Commins, Bradley T. Hyman, Naomi Klickstein, Matthew P. Frosch, Simon Dujardin, Tarun V. Kamath, Analiese R. Fernandes, Derek H. Oakley

المصدر: Brain Communications

مصطلحات موضوعية: 0301 basic medicine, Future studies, Growth phase, Tau protein, Kinetics, 03 medical and health sciences, 0302 clinical medicine, propagation, medicine, Bioassay, tau, biology, Chemistry, AcademicSubjects/SCI01870, General Engineering, Human brain, Patient specific, medicine.disease, Editor's Choice, 030104 developmental biology, medicine.anatomical_structure, kinetics, biology.protein, Biophysics, Original Article, AcademicSubjects/MED00310, Alzheimer's disease, heterogeneity, 030217 neurology & neurosurgery, seeding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4578b1f2f301413149cb507766d9d9cTest
https://pubmed.ncbi.nlm.nih.gov/34222869Test

المؤلفون: Bradley T. Hyman, Naomi Klickstein, Marc Aurel Busche, George A. Carlson, Tarun V. Kamath, Julia Schiantarelli, Israel Nelken, Susanne Wegmann, Simon Dujardin, Caitlin Commins

المصدر: Nature reviews / Neuroscience 22(1), 57-64 (2018). doi:10.1038/s41593-018-0289-8

مصطلحات موضوعية: 0301 basic medicine, Genetically modified mouse, genetics [Plaque, Amyloid], pathology [Nerve Net], genetics [Alzheimer Disease], Plaque, Amyloid, tau Proteins, Article, 03 medical and health sciences, pathology [Alzheimer Disease], Mice, 0302 clinical medicine, In vivo, pathology [Brain], Alzheimer Disease, ddc:570, Gene expression, mental disorders, Biological neural network, medicine, Gene silencing, pathology [Neurons], Animals, Cognitive decline, metabolism [Nerve Net], Neurons, Neocortex, Chemistry, General Neuroscience, Brain, Neurofibrillary Tangles, Entorhinal cortex, metabolism [Plaque, Amyloid], metabolism [tau Proteins], genetics [tau Proteins], Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, metabolism [Neurofibrillary Tangles], metabolism [Brain], metabolism [Neurons], pathology [Neurofibrillary Tangles], Nerve Net, Neuroscience, 030217 neurology & neurosurgery, metabolism [Alzheimer Disease]

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29983d3e8c01d73ef951fcb7d2301504Test
https://pubmed.ncbi.nlm.nih.gov/30559471Test