التفاصيل البيبلوغرافية
العنوان:
Epilepsy in tuberous sclerosis complex: Findings from the TOSCA Study
المؤلفون:
Nabbout, R , Belousova, E , Benedik, Mp , Carter, T , Cottin, V , Curatolo, P , Dahlin, M , Damato, L , D'Augeres, Gb , de Vries, Pj , Ferreira, Jc , Feucht, M , Fladrowski, C , Hertzberg, C , Jozwiak, S , Lawson, Ja , Macaya, A , Marques, R , O'Callaghan, F , Qin, J , Sander, V , Sauter, M , Shah, S , Takahashi, Y , Touraine, R , Youroukos, S , Zonnenberg, B , Jansen, A , Kingswood, Jc , Shinohara, N , Horie, S , Kubota, M , Tohyama, J , Imai, K , Kaneda, M , Kaneko, H , Uchida, Y , Endo, S , Inoue, Y , Uruno, K , Serdaroglu, A , Yapici, Z , Anlar, B , Altunbasak, S , Lvova, O , Valeryevich Belyaev, O , Agranovich, O , Vladislavovna Levitina, E , Vladimirovna Maksimova, Y , Karas, A , Jiang, Y , Zou, L , Xu, K , Zhang, Y , Luan, G , Wang, Y , Jin, M , Ye, D , Liao, W , Zhou, L , Liu, J , Liao, J , Yan, B , Deng, Y , Jiang, L , Liu, Z , Huang, S , Li, H , Kim, K , Chen, P , Lee, H , Tsai, J , Chi, C , Huang, C , Riney, K , Yates, D , Kwan, P , Likasitwattanakul, S , Nabangchang, C , Thampratankul Krisnachai Chomtho, L , Katanyuwong, K , Sriudomkajorn, S , Wilmshurst, J , Segel, R , Gilboa, T , Tzadok, M , Fattal-Valevski, A , Papathanasopoulos, P , Syrigou Papavasiliou, A , Giannakodimos, S , Gatzonis, S , Pavlou, E , Tzoufi, M , Dhooghe, M , Verhelst, H , Roelens, F , Cecile Nassogne, M , Defresne, P , De Waele, L , Leroy, P , Demonceau, N , Van Bogaert, P , Ceulemans, B , Dom, L , Castelnau, P , De Saint Martin, A , Riquet, A , Milh, M , Cances, C , Pedespan, J , Ville, D , Roubertie, A , Auvin, S , Berquin, P , Richelme, C , Allaire, C , Gueden, S , Nguyen The Tich, S , Godet, B , Rojas, Mlrf , Planas, Jc , Bermejo, Am , Dura, Ps , Aparicio, Sr , Gonzalez, Mjm , Pison, Jl , Blanco Barca, Mo , Laso, El , Luengo, Oa , Rodriguez, Fja , Dieguez, Im , Salas, Ac , Carrera, Im , Salcedo, Em , Petri, Mey , Candela, Rc , Carrilho, Idc , Vieira, Jp , Monteiro, Jpdso , Leao, Mjsdof , Luis, Csmr , Pires Mendonca, C , Endziniene, M , Strautmanis, J , Talvik, I , Canevini, Mp , Gambardella, A , Pruna, D , Buono, S , Fontana, E , Bernardina, Bd , Burloiu, C , Cosma, Isb , Vintan, Ma , Popescu, L , Zitterbart, K , Payerova, J , Bratsky, L , Zilinska, Z , Gruber-Sedlmayr, U , Haberlandt, E , Rostasy, K , Pataraia, E , Elmslie, F , Ann Johnston, C , Crawford, P , Uldall, P , Uvebrant, P , Rask, O , Bjoernvold, M , Sloerdahl, A , Solhoff, R , Jaatun, Msg , Mandera, M , Radzikowska, Ej , Wysocki, M , Fischereder, M , Kurlemann, G , Wilken, B , Wiemer-Kruel, A , Budde, K , Marquard, K , Knuf, M , Hahn, A , Hartmann, H , Merkenschlager, A , Trollmann, R
المصدر:
Epilepsia Open
سنة النشر:
2019
مصطلحات موضوعية:
0301 basic medicine , medicine.medical_specialty , Pediatrics , Neurology , Disease , tuberous sclerosis complex , 030105 genetics & heredity , registry , 03 medical and health sciences , Tuberous sclerosis , Epilepsy , 0302 clinical medicine , Intellectual disability , medicine , Seizure control , TOSCA , business.industry , epilepsy , medicine.disease , Settore MED/39 - Neuropsichiatria Infantile , 3. Good health , medicine.anatomical_structure , Cohort , Full‐length Original Research , Neurology (clinical) , TSC1 , business , 030217 neurology & neurosurgery
الوصف:
Summary Objective To present the baseline data of the international TuberOus SClerosis registry to increase disease Awareness (TOSCA) with emphasis on the characteristics of epilepsies associated with tuberous sclerosis complex (TSC). Methods Retrospective and prospective patients’ data on all aspects of TSC were collected from multiple countries worldwide. Epilepsy variables included seizure type, age at onset, type of treatment, and treatment outcomes and association with genotype, seizures control, and intellectual disability. As for noninterventional registries, the study protocol did not specify any particular clinical instruments, laboratory investigations, or intervention. Evaluations included those required for diagnosis and management following local best practice. Results Epilepsy was reported in 83.6% of patients (1852/2216) at baseline; 38.9% presented with infantile spasms and 67.5% with focal seizures. The mean age at diagnosis of infantile spasms was 0.4 year (median
اللغة:
English
الوصول الحر:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0230368dd4d2223442bb9ce86b019b2fTest http://hdl.handle.net/2108/212732Test
حقوق:
OPEN
رقم الانضمام:
edsair.doi.dedup.....0230368dd4d2223442bb9ce86b019b2f
قاعدة البيانات:
OpenAIRE
