Infrared thermography is an effective, noninvasive measure of HPA activation
| العنوان: | Infrared thermography is an effective, noninvasive measure of HPA activation |
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| المؤلفون: | Jacob S. Francis, Paul Macaballug, Hao Chen, Shelly Tang, Jenny Q. Ouyang, Kristiana Hodach |
| المصدر: | Stress |
| بيانات النشر: | Informa UK Limited, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Hypothalamo-Hypophyseal System, endocrine system, medicine.medical_specialty, Physiology, Pituitary-Adrenal System, Natural variation, Article, Dexamethasone, 03 medical and health sciences, Behavioral Neuroscience, 0302 clinical medicine, Internal medicine, medicine, Glucocorticoids, Physiological stress, Endocrine and Autonomic Systems, Chemistry, 030227 psychiatry, Psychiatry and Mental health, Neuropsychology and Physiological Psychology, Endocrinology, Glucocorticoid secretion, Thermography, Body Temperature Changes, Adrenal tissue, Stress, Psychological, hormones, hormone substitutes, and hormone antagonists, 030217 neurology & neurosurgery, Glucocorticoid, medicine.drug |
| الوصف: | Infrared thermography (IRT) is increasingly applied as a noninvasive technique for measuring surface body temperature changes related to physiological stress. As a basis for validation of IRT as a tool for diagnostic use, we need to assess its potential to measure hypothalamic-pituitary-adrenal (HPA) axis reactivity. We used experimental manipulations of the HPA axis in house sparrows (Passer domesticus), i.e. adrenal tissue responsiveness to exogenous adrenocorticotropin (ACTH) and the efficacy of negative feedback using the synthetic glucocorticoid dexamethasone (DEX), to test whether IRT is an effective tool for measuring HPA reactivity. Experimental birds showed a pronounced decrease in skin temperatures after ACTH injection and an increase in temperature after DEX injection. However, individual variation in glucocorticoid levels were not related to skin temperatures except after ACTH injection in experimental birds. We show that IRT can be used to measure HPA reactivity but that skin-temperature is not a good index for glucocorticoid secretion at baseline levels. These results suggest that while IRT of skin temperatures is a useful, noninvasive measure of HPA axis reactivity under acute activation, this technique might not be suitable for measuring natural variation of circulating glucocorticoid levels. |
| تدمد: | 1607-8888 1025-3890 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce5b0d18679cd6be04770d32cc976480Test https://doi.org/10.1080/10253890.2020.1868431Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....ce5b0d18679cd6be04770d32cc976480 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16078888 10253890 |
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