المؤلفون: Fabio Coppedè

المصدر: The Application of Clinical Genetics

مصطلحات موضوعية: 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, DNA repair, Review, Bioinformatics, restrictive dermopathy, Progeroid syndromes, 03 medical and health sciences, 0302 clinical medicine, atypical progeroid syndromes, Genetics, medicine, Genetics (clinical), Werner syndrome, Progeria, Hutchinson–Gilford progeria syndrome, integumentary system, Genetic heterogeneity, business.industry, Néstor-Guillermo progeria syndrome, nutritional and metabolic diseases, Atypical progeroid syndromes, Hutchinson-gilford progeria syndrome, Mandibuloacral dysplasia, Néstor-guillermo progeria syndrome, Restrictive dermopathy, medicine.disease, Hypoplasia, 030104 developmental biology, business, 030217 neurology & neurosurgery, mandibuloacral dysplasia

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb2fe17d6122e15ef63995e77851912bTest
https://pubmed.ncbi.nlm.nih.gov/34103969Test

المؤلفون: Ian R. Kill, Wendy Ofosu, Joanna M. Bridger, Craig S. Clements, Evgeny M. Makarov, David Tree, Christopher H. Eskiw, Mehmet U. Bikkul

المصدر: Biogerontology

مصطلحات موضوعية: 0301 basic medicine, Aging, N-acetyl cysteine, Farnesyltransferase, Hutchinson-Gilford Progeria Syndrome, Progerin, LMNA, zoledronic acid, 0302 clinical medicine, Progeria, Enzyme Inhibitors, Pravastatin, farnesyl transferase inhibitors, pravastatin, biology, integumentary system, Chemistry, Lamin Type A, embryonic structures, Mevalonate pathway, medicine.drug, Research Article, congenital, hereditary, and neonatal diseases and abnormalities, Mevalonic Acid, Cell Line, 03 medical and health sciences, Internal lamin foci, medicine, Humans, Rapamycin, PI3K/AKT/mTOR pathway, Zoledronic acid, nuclear lamins, Hutchinson–Gilford progeria syndrome, rapamycin, Farnesyl transferase inhibitors, nutritional and metabolic diseases, medicine.disease, 030104 developmental biology, progerin, biology.protein, Cancer research, Nuclear lamins, Geriatrics and Gerontology, Gerontology, 030217 neurology & neurosurgery, Lamin

وصف الملف: Print-Electronic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f6b2fd09330521c2ec71ca71051a6afTest
http://europepmc.org/articles/PMC6535420Test

المؤلفون: Wing-Fu Lai, Wing Tak Wong

المصدر: Aging Cell

مصطلحات موضوعية: 0301 basic medicine, Premature aging, Aging, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, Laminopathy, Disease, Review, laminopathy, Biology, 03 medical and health sciences, 0302 clinical medicine, Progeria, Intervention (counseling), medicine, Humans, Intensive care medicine, Hutchinson–Gilford progeria syndrome, integumentary system, treatment, premature aging, Intervention design, nutritional and metabolic diseases, Cell Biology, Syndrome, medicine.disease, 030104 developmental biology, Physiological Aging, Disease Progression, Hutchinson Gilford Progeria Syndrome, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c822d7568f6bd2850914a2f77460542cTest
https://pubmed.ncbi.nlm.nih.gov/32596971Test

المؤلفون: Leili Yekefallah, Sareh Mohammadi, Siamak Yaghoubi, Ameneh Bagheri, Alireza Taromiha

المصدر: The Journal of Qazvin University of Medical Sciences, Vol 23, Iss 1, Pp 84-91 (2019)

مصطلحات موضوعية: 0301 basic medicine, Premature aging, Pediatrics, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, lcsh:Medicine, Disease, 03 medical and health sciences, 0302 clinical medicine, Progeria, medicine, Myocardial infarction, Survival rate, Stroke, integumentary system, business.industry, lcsh:R, nutritional and metabolic diseases, medicine.disease, Appendicitis, 030104 developmental biology, business, Hutchinson Gilford Progeria Syndrome, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b948db5b8ba39f19d80505394c2509b5Test
http://journal.qums.ac.ir/article-1-2567-en.htmlTest

المؤلفون: Samuel Corless, Felix Bormann, Julian Gutekunst, Frank Lyko, Manuel Rodríguez-Paredes, Günter Raddatz, Tanja Musch, Sylvia Erhardt, Anke S. Lonsdorf, Florian Köhler

المصدر: Genome Medicine
Genome Medicine, Vol 12, Iss 1, Pp 1-16 (2020)

مصطلحات موضوعية: Premature aging, congenital, hereditary, and neonatal diseases and abnormalities, Aging, lcsh:QH426-470, Lamina-associated domains (LADs), lcsh:Medicine, Biology, Cell Line, Epigenesis, Genetic, 03 medical and health sciences, Progeria, 0302 clinical medicine, Protein Domains, Genetics, medicine, Humans, Epigenetics, Molecular Biology, Genetics (clinical), 030304 developmental biology, Werner syndrome, Chromatin accessibility, 0303 health sciences, DNA methylation, integumentary system, Research, lcsh:R, nutritional and metabolic diseases, Fibroblasts, Lamin Type A, medicine.disease, Progerin, Hutchinson-Gilford progeria syndrome, 3. Good health, Cell biology, Chromatin, lcsh:Genetics, Gene Expression Regulation, Molecular Medicine, 030217 neurology & neurosurgery, Lamin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b39b127c01bafb162e01fde300bc71eTest
https://doi.org/10.1186/s13073-020-00749-yTest

المؤلفون: Jesús Vázquez, Vicente Andrés, José Rivera-Torres, Beatriz Dorado, Cristina González-Gómez, Inmaculada Jorge, Ana Barettino, Alvaro Macias, Emilio Camafeita, María J. Andrés-Manzano, Carlos López-Otín, Víctor Fanjul

المساهمون: Ministerio de Ciencia e Innovación (España), Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF), Instituto de Salud Carlos III, Fundación La Marató TV3, Fundación La Caixa, Progeria Research Foundation, Fundación ProCNIC, European Regional Development Fund (ERDF/FEDER), Instituto de Salud Carlos III - ISCIII, Fundació La Marató

المصدر: RUO: Repositorio Institucional de la Universidad de Oviedo
Universidad de Oviedo (UNIOVI)
Repisalud
Instituto de Salud Carlos III (ISCIII)
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
ABACUS. Repositorio de Producción Científica
Universidad Europea (UEM)
Aging Cell

مصطلحات موضوعية: 0301 basic medicine, Proteomics, Aging, Swine, Enfermedad cardiovascular, Envejecimiento, Biology, Protein oxidation, Bioinformatics, 03 medical and health sciences, Mice, 0302 clinical medicine, Progeria, Glycation, medicine, Animals, Humans, mouse models, Risk factor, pathophysiology, pig models, cardiometabolic disease, Hutchinson–Gilford progeria syndrome, integumentary system, Cell Biology, Original Articles, medicine.disease, Pathophysiology, Disease Models, Animal, 030104 developmental biology, Proteostasis, Cardiovascular Diseases, Heart failure, HGPS, Original Article, 030217 neurology & neurosurgery, Célula

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50b4d1c300dd6743871c47c547e973eTest
http://hdl.handle.net/10651/56245Test

المؤلفون: Manuela Teresa Raimondi, Emanuela Jacchetti, Francesca Donnaloja, Federica Carnevali

المصدر: Cells
Cells, Vol 9, Iss 1306, p 1306 (2020)

مصطلحات موضوعية: Emery-Dreyfuss muscular dystrophy, Hutchinson Gilford progeria syndrome, gene regulation, lamin A/C, lamin partners, laminopathy, mechanotransduction, Laminopathy, Review, Biology, Mechanotransduction, Cellular, Chromatin remodeling, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Humans, Mechanotransduction, Mitosis, lcsh:QH301-705.5, 030304 developmental biology, Regulation of gene expression, 0303 health sciences, Laminopathies, General Medicine, medicine.disease, Lamin Type A, Chromatin, Cell biology, lcsh:Biology (General), Mutation, Nuclear lamina, 030217 neurology & neurosurgery, Lamin, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c330e87980ab0ef77345067136eed310Test
http://hdl.handle.net/11311/1137194Test

المؤلفون: Cristiano Petrini, Chiara Lanzuolo, Gennaro Oliva, Endre Sebestyén, Federica Lucini, Sara Valsoni, Francesco Ferrari, Louis Antonelli, Andrea Bianchi, Francesco Gregoretti, Fabrizia Marullo, Ilaria Olivieri

المصدر: Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature communications 11 (2020): 6274. doi:10.1038/s41467-020-20048-9
info:cnr-pdr/source/autori:Sebestyen E, Marullo F, Lucini F, Petrini C, Bianchi A, Valsoni S, Olivieri I, Antonelli L, Gregoretti F, Oliva G, Ferrari F, Lanzuolo C./titolo:SAMMY-seq reveals early alteration of heterochromatin and deregulation of bivalent genes in Hutchinson-Gilford Progeria Syndrome/doi:10.1038%2Fs41467-020-20048-9/rivista:Nature communications/anno:2020/pagina_da:6274/pagina_a:/intervallo_pagine:6274/volume:11

مصطلحات موضوعية: 0301 basic medicine, General Physics and Astronomy, Datasets as Topic, Polycomb-Group Proteins, Hutchinson-Gilford Progeria Syndrome, Histones, 0302 clinical medicine, Progeria, Heterochromatin, Histone post-translational modifications, RNA-Seq, Child, Cells, Cultured, Skin, Multidisciplinary, integumentary system, SAMMY-seq, Lamin Type A, Chromatin, Cell biology, Histone Code, Child, Preschool, embryonic structures, Chromatin Immunoprecipitation Sequencing, Transcriptional Activation, congenital, hereditary, and neonatal diseases and abnormalities, Science, Primary Cell Culture, Biology, General Biochemistry, Genetics and Molecular Biology, Chromatin remodeling, Bivalent (genetics), Article, 03 medical and health sciences, Chromatin analysis, medicine, Humans, Psychological repression, Gene, Nuclear organization, fungi, nutritional and metabolic diseases, General Chemistry, Fibroblasts, medicine.disease, Gene regulation, 030104 developmental biology, 030217 neurology & neurosurgery, Lamin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca8574e26d8af1183ec0f4c4f1005097Test
https://pubmed.ncbi.nlm.nih.gov/33293552Test

المؤلفون: Giovanna Lattanzi, Fabrizio d'Adda di Fagagna, Peh Fern Ong, Corey Winston Jones-Weinert, Oliver Dreesen, Claudio Tripodo, Agustin Sola-Carvajal, Maria Eriksson, Francesca Rossiello, Emelie Wallén Arzt, Gwladys Revêchon, Valeria Cancila, Julio Aguado

المساهمون: Aguado J., Sola-Carvajal A., Cancila V., Revechon G., Ong P.F., Jones-Weinert C.W., Wallen Arzt E., Lattanzi G., Dreesen O., Tripodo C., Rossiello F., Eriksson M., d'Adda di Fagagna F.

المصدر: Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)

مصطلحات موضوعية: 0301 basic medicine, Genome instability, RNA, Untranslated, DNA Repair, General Physics and Astronomy, Cellular homeostasis, Antisense oligonucleotide therapy, Mice, 0302 clinical medicine, Progeria, Homeostasis, lcsh:Science, Cellular Senescence, Skin, Multidisciplinary, integumentary system, Telomere, Progerin, Lamin Type A, 3. Good health, Cell biology, Telomeres, Phenotype, Premature aging, congenital, hereditary, and neonatal diseases and abnormalities, DNA repair, Science, Double-strand DNA breaks, Biology, Settore MED/08 - Anatomia Patologica, General Biochemistry, Genetics and Molecular Biology, Article, Cell Line, 03 medical and health sciences, medicine, DNA damage, Hutchinson-Gilford Progeria Syndrome, Animals, Cell Proliferation, nutritional and metabolic diseases, General Chemistry, Oligonucleotides, Antisense, medicine.disease, Disease Models, Animal, 030104 developmental biology, Mutation, lcsh:Q, 030217 neurology & neurosurgery, Lamin, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::116065ba15576e79b089c76198c4ab13Test
http://europepmc.org/articles/PMC6861280Test

المؤلفون: Sophie Sleiman, François Dragon

المصدر: Cells, Vol 8, Iss 9, p 1035 (2019)
Cells

مصطلحات موضوعية: Saccharomyces cerevisiae Proteins, Nucleolus, Nuclear Localization Signals, Active Transport, Cell Nucleus, Ribosome biogenesis, ribosome biogenesis, nucleolar localization signal, Review, Biology, Ribosome, post-transcriptional modifications, N-Terminal Acetyltransferases, 03 medical and health sciences, Progeria, 0302 clinical medicine, Acetyltransferases, Ribosomal protein, nuclear pore complex, Animals, Humans, Eukaryotic Small Ribosomal Subunit, RNA Processing, Post-Transcriptional, lcsh:QH301-705.5, 030304 developmental biology, 0303 health sciences, Hutchinson–Gilford progeria syndrome, RNA, General Medicine, Ribosomal RNA, nuclear localization signal, Cell biology, NAT10, Kre33, lcsh:Biology (General), Acetyltransferase, Cell Nucleolus, 030217 neurology & neurosurgery, SSU processome

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14fea75c5c665e157d11662e7e37096aTest
https://www.mdpi.com/2073-4409/8/9/1035Test