نتائج البحث - "David J. Brooks"

1

Asymmetric Dopaminergic Dysfunction in Brain-First versus Body-First Parkinson’s Disease Subtypes

المؤلفون: Casper Skjærbæk, Eva Schaeffer, Per Borghammer, Nathalie Van Den Berge, Tatyana D. Fedorova, Katrine B. Andersen, Jacob Horsager, Nicola Pavese, David J. Brooks, Daniela Berg, Karoline Knudsen

المصدر: Knudsen, K, Fedorova, T D, Horsager, J, Andersen, K B, Skjærbæk, C, Berg, D, Schaeffer, E, Brooks, D J, Pavese, N, Van Den Berge, N & Borghammer, P 2021, ' Asymmetric Dopaminergic Dysfunction in Brain-First versus Body-First Parkinson's Disease Subtypes ', Journal of Parkinson's Disease, vol. 11, no. 4, pp. 1677-1687 . https://doi.org/10.3233/JPD-212761Test

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Parkinson's disease, Dopamine, PROGRESSION, REM Sleep Behavior Disorder, Binding ratio, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Internal medicine, medicine, Humans, dopaminergic dysfunction, In patient, SCREENING QUESTIONNAIRE, Nigrostriatal degeneration, Tomography, Emission-Computed, Single-Photon, Dopamine Plasma Membrane Transport Proteins, business.industry, Putamen, Dopaminergic, Brain, Parkinson Disease, medicine.disease, PATHOLOGY, 030104 developmental biology, Endocrinology, SLEEP BEHAVIOR DISORDER, alpha-Synuclein, Sleep behavior, Neurology (clinical), Brainstem, business, brain- and body-first, asymmetry, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04ab5bb40bc7fad9531656be8be43eb7Test
https://doi.org/10.3233/jpd-212761Test

2

Reduced Synaptic Density in Patients with Lewy Body Dementia: An [ 11 C ] UCB‐J PET Imaging Study

المؤلفون: Erik H. Danielsen, Per Borghammer, Malene Flensborg Damholdt, Casper Skjærbæk, Jacob Horsager, David J. Brooks, Anna C. Schacht, Hanne Gottrup, Allan K Hansen, Henriette Klit, Katrine B. Andersen

المصدر: Andersen, K B, Hansen, A K, Damholdt, M F, Horsager, J, Skjaerbaek, C, Gottrup, H, Klit, H, Schacht, A C, Danielsen, E H, Brooks, D J & Borghammer, P 2021, ' Reduced Synaptic Density in Patients with Lewy Body Dementia : An [ 11 C-]UCB-J PET Imaging Study ', Movement Disorders, vol. 36, no. 9, pp. 2057-2065 . https://doi.org/10.1002/mds.28617Test

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9750704b9dbf19797286345c50f195d4Test
https://doi.org/10.1002/mds.28617Test

3

Cortical cholinergic dysfunction correlates with microglial activation in the substantia innominata in REM sleep behavior disorder

المؤلفون: Kristina Bacher Svendsen, Alex Iranzo, Nicola Pavese, Dolores Vilas, David J. Brooks, Eduardo Tolosa, Alicia Garrido, Morten Gersel Stokholm, Marit Otto, Arne Møller, Kristian Stær, Mónica Serradell, Per Borghammer, Joan Santamaria, Karen Østergaard, Carles Gaig

المصدر: Stær, K, Iranzo, A, Stokholm, M G, Østergaard, K, Serradell, M, Otto, M, Svendsen, K B, Garrido, A, Vilas, D, Santamaria, J, Møller, A, Gaig, C, Brooks, D J, Borghammer, P, Tolosa, E & Pavese, N 2020, ' Cortical cholinergic dysfunction correlates with microglial activation in the substantia innominata in REM sleep behavior disorder ', Parkinsonism & Related Disorders, vol. 81, pp. 89-93 . https://doi.org/10.1016Test/j.parkreldis.2020.10.014

مصطلحات موضوعية: Male, 0301 basic medicine, Parkinson's disease, Substantia nigra, REM Sleep Behavior Disorder, REM sleep behavior disorder, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Substantia Innominata, medicine, Humans, Cognitive Dysfunction, Donepezil, Carbon Radioisotopes, Neuroinflammation, Aged, Cerebral Cortex, Inflammation, business.industry, Substantia innominata, Middle Aged, Isoquinolines, Mental Status and Dementia Tests, medicine.disease, Acetylcholinesterase, Cortex (botany), 030104 developmental biology, Neurology, chemistry, Positron-Emission Tomography, Cholinergic, Female, Cholinesterase Inhibitors, Microglia, Neurology (clinical), Geriatrics and Gerontology, business, Neuroscience, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6a4ee8ab93f9a2856d261984fb1f930Test
https://doi.org/10.1016Test/j.parkreldis.2020.10.014

4

Progression of sleep disturbances in Parkinson’s disease: a 5-year longitudinal study

المؤلفون: Rachael A Lawson, Seyed Ehsan Saffari, David J. Brooks, Zheyu Xu, Kirstie N. Anderson, Nicola Pavese, K. Ray Chaudhuri

المصدر: Xu, Z, Anderson, K N, Saffari, S E, Lawson, R A, Chaudhuri, K R, Brooks, D & Pavese, N 2021, ' Progression of sleep disturbances in Parkinson's disease : a 5-year longitudinal study ', Journal of Neurology, vol. 268, no. 1, pp. 312-320 . https://doi.org/10.1007/s00415-020-10140-xTest
Journal of Neurology

مصطلحات موضوعية: Sleep Wake Disorders, Pediatrics, medicine.medical_specialty, Insomnia, Neurology, Parkinson's disease, Excessive daytime sleepiness, REM Sleep Behavior Disorder, REM sleep behavior disorder, RBD, EDS, 03 medical and health sciences, PPMI, 0302 clinical medicine, DISORDER SCREENING QUESTIONNAIRE, QUALITY-OF-LIFE, Humans, BEHAVIOR DISORDER, Medicine, Longitudinal Studies, 030212 general & internal medicine, Sleep disorder, Original Communication, business.industry, Epworth Sleepiness Scale, Parkinson Disease, medicine.disease, Sleep in non-human animals, DYSFUNCTION, EVOLUTION, PREVALENCE, EXCESSIVE DAYTIME SLEEPINESS, Parkinson’s disease, EARLY-STAGE, Neurology (clinical), medicine.symptom, Sleep, NONMOTOR SYMPTOMS, business, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f34b78919ca0a5379e48b273c65b102aTest
https://doi.org/10.1007/s00415-020-10140-xTest

5

Progressive loss of raphe nuclei serotonin transporter in early Parkinson's disease: A longitudinal 123I-FP-CIT SPECT study

المؤلفون: Ubaldo Bonuccelli, Nicola Pavese, Roberto Ceravolo, Jacopo Pasquini, David J. Brooks

المصدر: Pasquini, J, Ceravolo, R, Brooks, D J, Bonuccelli, U & Pavese, N 2020, ' Progressive loss of raphe nuclei serotonin transporter in early Parkinson's disease : A longitudinal 123 I-FP-CIT SPECT study ', Parkinsonism & Related Disorders, vol. 77, pp. 170-175 . https://doi.org/10.1016Test/j.parkreldis.2019.03.025

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a81e4ce802d76873a301037f59aa9f86Test
https://doi.org/10.1016Test/j.parkreldis.2019.03.025

6

In vivo imaging of synaptic SV2A protein density in healthy and striatal-lesioned rats with [11C]UCB-J PET

المؤلفون: David J. Brooks, Anne M. Landau, Majken B. Thomsen, Anna C. Schacht, Thea P. Lillethorup, Jan Jacobsen, Mette Kildevæld Simonsen, Marina Romero-Ramos

المصدر: Thomsen, M, Jacobsen, J, Lillethorup, T P, Schacht, A C, Simonsen, M I T, Romero-Ramos, M, Brooks, D J & Landau, A 2021, ' In vivo imaging of synaptic SV2A protein density in healthy and striatal-lesioned rats with [11C]UCB-J PET ', Journal of Cerebral Blood Flow and Metabolism, vol. 41, no. 4, pp. 819-830 . https://doi.org/10.1177/0271678X20931140Test
J Cereb Blood Flow Metab

مصطلحات موضوعية: Levetiracetam, Nerve Tissue Proteins, Pharmacology, Synaptic vesicle, Neuroprotection, Rats, Sprague-Dawley, Synapse, Lesion, Hydroxydopamines, 03 medical and health sciences, chemistry.chemical_compound, fluids and secretions, 0302 clinical medicine, synapse, In vivo, medicine, Animals, rat, Parkinson Disease, Secondary, 030304 developmental biology, SV2A, 0303 health sciences, Membrane Glycoproteins, Chemistry, Neurodegeneration, neurodegeneration, Original Articles, Quinolinic Acid, medicine.disease, Corpus Striatum, Rats, SV2A protein, Kinetics, Huntington Disease, Neuroprotective Agents, [11C]UCB-J PET, Neurology, Positron-Emission Tomography, Synapses, embryonic structures, Autoradiography, Anticonvulsants, Female, Neurology (clinical), Radiopharmaceuticals, medicine.symptom, Cardiology and Cardiovascular Medicine, 030217 neurology & neurosurgery, Quinolinic acid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d936e22954b72b8ef486a681c907b897Test
https://doi.org/10.1177/0271678x20931140Test

7

Imaging dopamine function and microglia in asymptomatic LRRK2 mutation carriers

المؤلفون: Per Borghammer, Karen Østergaard, Peter Parbo, Arne Møller, Kristian Stær, David J. Brooks, Nicola Pavese, Alicia Garrido, Eduardo Tolosa, Morten Gersel Stokholm, Mónica Serradell, María José Martí, Alex Iranzo

المصدر: Stokholm, M G, Garrido, A, Tolosa, E, Serradell, M, Iranzo, A, Ostergaard, K, Borghammer, P, Moller, A, Parbo, P, Staer, K, Brooks, D J, Jose Marti, M & Pavese, N 2020, ' Imaging dopamine function and microglia in asymptomatic LRRK2 mutation carriers ', Journal of Neurology, vol. 267, no. 8, pp. 2296-2300 . https://doi.org/10.1007/s00415-020-09830-3Test
Journal of Neurology

مصطلحات موضوعية: 0301 basic medicine, PENETRANCE, medicine.medical_specialty, Parkinson's disease, Neurology, Dopamine, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Asymptomatic, DISEASE, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Genetics, medicine, Humans, Movement disorders, Neuroinflammation, Subclinical infection, Original Communication, Microglia, business.industry, Parkinsonism, SYNUCLEINOPATHIES, Parkinson Disease, medicine.disease, nervous system diseases, PATHOLOGY, PET, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Clinical neurology, Mutation, Parkinson’s disease, Neurology (clinical), medicine.symptom, business, 030217 neurology & neurosurgery, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d9ae05a56f269dd603e6775f67cce3Test
https://doi.org/10.1007/s00415-020-09830-3Test

8

Cholinergic denervation in patients with idiopathic rapid eye movement sleep behaviour disorder

المؤلفون: Joan Santamaria, Tatyana D. Fedorova, Kotaro Hiraoka, Alicia Garrido, Marit Otto, Nobuyuki Okamura, Anette Torvin Møller, Alex Iranzo, Carles Gaig, Dolores Vilas, M. Gersel Stokholm, Eduard Tolosa, Karen Østergaard, David J. Brooks, Nicola Pavese, Per Borghammer, Mónica Serradell, K. Bacher Svendsen

المصدر: Gersel Stokholm, M, Iranzo, A, Østergaard, K, Serradell, M, Otto, M, Bacher Svendsen, K, Garrido, A, Vilas, D, Fedorova, T D, Santamaria, J, Møller, A, Gaig, C, Hiraoka, K, Brooks, D J, Okamura, N, Borghammer, P, Tolosa, E & Pavese, N 2020, ' Cholinergic denervation in patients with idiopathic rapid eye movement sleep behaviour disorder ', European Journal of Neurology, vol. 27, no. 4, pp. 644-652 . https://doi.org/10.1111/ene.14127Test

مصطلحات موضوعية: DOPAMINERGIC DEFICITS, Male, Cingulate cortex, positron emission tomography, Parkinson's disease, Polysomnography, REM Sleep Behavior Disorder, Lewy body disease, DIAGNOSIS, 03 medical and health sciences, 0302 clinical medicine, PARKINSONS-DISEASE, mental disorders, MANAGEMENT, medicine, Cholinesterases, Humans, Dementia, 030212 general & internal medicine, rapid eye movement sleep behaviour disorder, Aged, Temporal cortex, Dementia with Lewy bodies, business.industry, DEMENTIA, Parkinsonism, NEURODEGENERATION, Brain, Montreal Cognitive Assessment, ACETYLTRANSFERASE ACTIVITY, Middle Aged, COGNITIVE IMPAIRMENT, medicine.disease, LEWY BODIES, Denervation, acetylcholine, Dihydroxyphenylalanine, ALZHEIMERS-DISEASE, Dorsolateral prefrontal cortex, medicine.anatomical_structure, Neurology, Positron-Emission Tomography, Female, Neurology (clinical), business, Neuroscience, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d6bb785d695e7d8b6bc98668eed9bcbTest
http://hdl.handle.net/10097/00130915Test

9

A new perspective for advanced positron emission tomography-based molecular imaging in neurodegenerative proteinopathies

المساهمون: Radiology and nuclear medicine, Amsterdam Neuroscience - Brain Imaging, ACS - Heart failure & arrhythmias, Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE), Chalon, Sylvie, VU University Medical Center [Amsterdam], Univ Groningen, Univ Med Ctr Groningen, Lund University [Lund], Perani, D, Iaccarino, L, Lammertsma, Aa, Windhorst, Ad, Edison, P, Boellaard, R, Hansson, O, Nordberg, A, Jacobs, A, on behalf of all partners of the IMBI, Project, Lammertsma, A, Windhorst, A, Bottlaender, M, Brooks, D, Carroll, M, Chalon, S, Gee, A, Gerhard, A, Halldin, C, Herholz, K, Herth, M, Hinz, R, Knudsen, G, Kuhnast, B, Lopez-Picon, F, Moresco, R, Pappata, S, Rinne, J, Rodriguez-Vieitez, E, Santiago-Ribeiro, M, Turkheimer, F, Van Laere, K, Varrone, A, Vercouillie, J, Winkeler, A

المصدر: Perani, D, Iaccarino, L, Lammertsma, A A, Windhorst, A D, Edison, P, Boellaard, R, Hansson, O, Nordberg, A, Jacobs, A H & IMBI Project 2019, ' A new perspective for advanced positron emission tomography–based molecular imaging in neurodegenerative proteinopathies ', Alzheimer's and Dementia, vol. 15, no. 8, pp. 1081-1103 . https://doi.org/10.1016Test/j.jalz.2019.02.004
Alzheimer's and Dementia, 15(8), 1081-1103. Elsevier
Perani, D, Iaccarino, L, Lammertsma, A A, Windhorst, A D, Edison, P, Boellaard, R, Hansson, O, Nordberg, A, Jacobs, A H & Partners IMBI Project 2019, ' A new perspective for advanced positron emission tomography-based molecular imaging in neurodegenerative proteinopathies ', Alzheimer's & Dementia, vol. 15, no. 8, pp. 1081-1103 . https://doi.org/10.1016Test/j.jalz.2019.02.004
Alzheimers & dementia, 15(8), 1081-1103. ELSEVIER SCIENCE INC
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, Wiley, 2019, 15 (8), pp.1081-1103. ⟨10.1016/j.jalz.2019.02.004⟩

مصطلحات موضوعية: 0301 basic medicine, 18-KDA TRANSLOCATOR PROTEIN, MILD COGNITIVE IMPAIRMENT, Epidemiology, PET TRACER F-18-AV-1451, [SDV]Life Sciences [q-bio], Diagnostic tools, Abnormal protein, AMYOTROPHIC-LATERAL-SCLEROSIS, chemistry.chemical_compound, 0302 clinical medicine, Neuroinflammation, Medicine, TAU-PET, ComputingMilieux_MISCELLANEOUS, IN-VIVO, medicine.diagnostic_test, Health Policy, Amyloid, Neuroinflammation, PET molecular imaging, Protheinopathies, Radiotracers, Tau, Neurodegenerative Diseases, Frontotemporal lobar degeneration, ALZHEIMERS ASSOCIATION WORKGROUPS, 3. Good health, [SDV] Life Sciences [q-bio], Psychiatry and Mental health, Radiotracers, Positron emission tomography, Protheinopathie, Specific protein, Amyloid, PET molecular imaging, Neuroimaging, Neuropathology, CEREBRAL AMYLOID ANGIOPATHY, 03 medical and health sciences, Cellular and Molecular Neuroscience, Developmental Neuroscience, Humans, Proteostasis Deficiencies, FRONTOTEMPORAL LOBAR DEGENERATION, Radiotracer, business.industry, PITTSBURGH COMPOUND-B, medicine.disease, 030104 developmental biology, chemistry, Positron-Emission Tomography, Protheinopathies, Neurology (clinical), Geriatrics and Gerontology, Molecular imaging, Tau, business, Pittsburgh compound B, Neuroscience, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5303c97f26d0a4c4daf3ecbe61eb94fTest
https://research.rug.nl/en/publications/31d7324a-6cc7-43e1-8d81-b70469a0330aTest

10

Exercise protects synaptic density in a rat model of Parkinson's disease

المؤلفون: David J. Brooks, Simone L. Baerentzen, M.N. Nielsen, Marucia Chacur, Karina Henrique Binda, Anne M. Landau, Thea P. Lillethorup, Caroline Cristiano Real, Dariusz Orlowski

المصدر: Binda, K H, Lillethorup, T P, Real, C C, Bærentzen, S L, Nielsen, M N, Orlowski, D, Brooks, D J, Chacur, M & Landau, A M 2021, ' Exercise protects synaptic density in a rat model of Parkinson's disease ', Experimental Neurology, vol. 342, pp. 113741 . https://doi.org/10.1016Test/j.expneurol.2021.113741
Binda, K H, Lillethorup, T P, Real, C C, Bærentzen, S L, Nielsen, M N, Orlowski, D, Brooks, D J, Chacur, M & Landau, A M 2021, ' Exercise protects synaptic density in a rat model of Parkinson's disease ', Experimental Neurology, pp. 113741 . https://doi.org/10.1016Test/j.expneurol.2021.113741
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Parkinson's disease, Synaptic density, Receptor expression, Dopamine, Substantia nigra, 6-OHDA, Opioid, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Parkinsonian Disorders, Developmental Neuroscience, Neuroinflammation, Physical Conditioning, Animal, Dopamine receptor D2, Internal medicine, Animals, Medicine, Parkinson, Rats, Wistar, Oxidopamine, Exercise, SV2A, Raclopride, SINAPSE, business.industry, Brain, medicine.disease, Rats, DAMGO, 030104 developmental biology, Endocrinology, Neurology, chemistry, nervous system, UCB-J, Synapses, Exercise Test, Autoradiography, business, 030217 neurology & neurosurgery, medicine.drug, Synaptic vesicle glycoprotein 2A

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4728cd22929c16ce1b3bcfe9e64038f5Test
https://pure.au.dk/portal/da/publications/exercise-protects-synaptic-density-in-a-rat-model-of-parkinsons-diseaseTest(e7d7d7ba-f7b3-4034-9fbb-fe548ee23002).html

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