The impact of frailty in aortic valve surgery
| العنوان: | The impact of frailty in aortic valve surgery |
|---|---|
| المؤلفون: | Antoni Bayes Genis, Enrique Moret Ruiz, Luis Delgado Ramis, Irma Casas Garcia, Maria Luisa Camara Rosell, Anna Llorens Ferrer, Ignasi Julia Almill, Claudio Fernandez Gallego, Elisabet Berastegui García, Sara Badia Gamarra, Christian Muñoz Guijosa, Bernat Romero Ferrer |
| المصدر: | BMC Geriatrics BMC Geriatrics, Vol 20, Iss 1, Pp 1-10 (2020) |
| بيانات النشر: | Research Square Platform LLC, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Multivariate analysis, Anemia, medicine.medical_treatment, Frail Elderly, Risk scales, lcsh:Geriatrics, 030204 cardiovascular system & hematology, Prosthesis, Risk Assessment, Transcatheter Aortic Valve Replacement, 03 medical and health sciences, 0302 clinical medicine, Aortic valve replacement, Quality of life, Risk Factors, Internal medicine, medicine, Humans, 030212 general & internal medicine, Prospective Studies, Prospective cohort study, Geriatric Assessment, Aged, Rehabilitation, Frailty, business.industry, Aortic Valve Stenosis, medicine.disease, Cardiac surgery, lcsh:RC952-954.6, Treatment Outcome, Aortic Valve, Cardiology, Quality of Life, Geriatrics and Gerontology, business, Research Article |
| الوصف: | Background Frailty is a geriatric syndrome that diminishes potential functional recovery after any surgical procedure. Preoperative surgical risk assessment is crucial to calibrate the risk and benefit of cardiac surgery. The aim of this study was to test usefulness of FRAIL Scale and other surgical-risk-scales and individual features of frailty in cardiac aortic valve surgery. Methods Prospective study. From May-2014 to February-2016, we collected 200 patients who underwent aortic valve replacement, either surgically or transcatheter. At 1-year follow-up, quality of life measurements were recorded using the EQ-5D (EuroQol). Univariate and multivariate analyses correlated preoperative condition, features of frailty and predicted risk scores with mortality, morbidity and quality of life at 1 year of follow-up. Results Mean age 78.2y, 56%male. Mean-preoperative-scores: FRAIL scale 1.5(SD 1.02), STS 2.9(SD 1.13), BI 93.8(SD 7.3), ESlog I 12.8(SD 8.5) and GS 7.3 s (SD 1.9). Morbidity at discharge, 6 m and 1 year was 51, 14 and 28%. Mortality 4%. Survival at 6 m/ 1-y was 97% / 88%. Complication-rate was higher in TAVI group due to-vascular complications. Renal dysfunction, anemia, social dependence and GS slower than 7 s were associated with morbidity. On multivariate analysis adjusted STS, BI and GS speed were statistically significant. Quality of life at 1-year follow-up adjusted for age and prosthesis type showed a significant association with STS and FRAIL scale scores. Conclusions Frailty increases surgical risk and is associated with higher morbidity. Preoperative GS slower 7 s, and STS and FRAIL scale scores seem to be reliable predictors of quality of life at 1-year follow-up. |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02688f2c103a20ef6bc36604c16d7b37Test https://doi.org/10.21203/rs.3.rs-19049/v3Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....02688f2c103a20ef6bc36604c16d7b37 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |