Socioeconomic Inequalities and Ethnicity Are Associated with a Positive COVID-19 Test among Cancer Patients in the UK Biobank Cohort
| العنوان: | Socioeconomic Inequalities and Ethnicity Are Associated with a Positive COVID-19 Test among Cancer Patients in the UK Biobank Cohort |
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| المؤلفون: | Maja Niksic, María José Sánchez, Bernard Rachet, Shing Fung Lee, Miguel Angel Luque-Fernandez |
| المساهمون: | [Lee,SF] Department of Clinical Oncology, Tuen Mun Hospital, New Territories West Cluster, Hospital Authority, Hong Kong. [Nikšić,M, Rachet,B, Luque-Fernandez,MA] Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK. [Rachet,B, Luque-Fernandez,MA] Inequalities in Cancer Outcomes Network, London School of Hygiene and Tropical Medicine, London, UK. [Sanchez,MJ, Luque-Fernandez,MA] Department of Non-Communicable Disease and Cancer Epidemiology, Instituto de Investigacion Biosanitaria de Granada (ibs.GRANADA), University of Granada, Granada, Spain. [Sanchez,MJ, Luque-Fernandez,MA] Cancer Registry of Granada, Andalusian School of Public Health, Granada, Spain. [Sanchez,MJ, Luque-Fernandez,MA] Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBER of Epidemiology and Public Health, CIBERESP), Madrid, Spain., M.A.L.-F. was supported by a Spanish National Health Institute Carlos III Miguel Servet-I Investigator grant/award, grant number CP17/00206-EU-FEDER and project grant, grant number EU-FEDER-FIS PI-18/01593. The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. |
| المصدر: | Digibug. Repositorio Institucional de la Universidad de Granada instname Cancers Volume 13 Issue 7 Cancers, Vol 13, Iss 1514, p 1514 (2021) Digibug: Repositorio Institucional de la Universidad de Granada Universidad de Granada (UGR) |
| بيانات النشر: | MDPI, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Cancer Research, medicine.medical_specialty, Health Care::Health Care Facilities, Manpower, and Services::Health Facilities::Biological Specimen Banks [Medical Subject Headings], Diseases::Neoplasms::Neoplasms by Site::Hematologic Neoplasms [Medical Subject Headings], Epidemiology, Infecciones por coronavirus, Ethnic group, pandemics, lcsh:RC254-282, Article, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors [Medical Subject Headings], Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], 03 medical and health sciences, 0302 clinical medicine, Information Science::Information Science::Data Collection::Vital Statistics::Morbidity::Incidence [Medical Subject Headings], Pandemic, medicine, risk factors, Epidemiología, Anthropology, Education, Sociology and Social Phenomena::Social Sciences::Sociology::Socioeconomic Factors [Medical Subject Headings], cancer, 030212 general & internal medicine, Socioeconomic status, Pandemias, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Biological Therapy::Immunomodulation::Immunotherapy::Immunization::Immunotherapy, Active::Vaccination [Medical Subject Headings], business.industry, Incidence (epidemiology), Cancer, Health Care::Environment and Public Health::Public Health::Disease Outbreaks::Epidemics::Pandemics [Medical Subject Headings], COVID-19, Diseases::Neoplasms [Medical Subject Headings], Cáncer, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, Biobank, Neoplasias, Oncology, Risk factors, 030220 oncology & carcinogenesis, Cohort, coronavirus disease 2019 (COVID-19), epidemiology, business, Demography, Factores de riesgo |
| الوصف: | We explored the role of socioeconomic inequalities in COVID-19 incidence among cancer patients during the first wave of the pandemic. We conducted a case-control study within the UK Biobank cohort linked to the COVID-19 tests results available from 16 March 2020 until 23 August 2020. The main exposure variable was socioeconomic status, assessed using the Townsend Deprivation Index. Among 18,917 participants with an incident malignancy in the UK Biobank cohort, 89 tested positive for COVID-19. The overall COVID-19 incidence was 4.7 cases per 1000 incident cancer patients (95%CI 3.8–5.8). Compared with the least deprived cancer patients, those living in the most deprived areas had an almost three times higher risk of testing positive (RR 2.6, 95%CI 1.1–5.8). Other independent risk factors were ethnic minority background, obesity, unemployment, smoking, and being diagnosed with a haematological cancer for less than five years. A consistent pattern of socioeconomic inequalities in COVID-19 among incident cancer patients in the UK highlights the need to prioritise the cancer patients living in the most deprived areas in vaccination planning. This socio-demographic profiling of vulnerable cancer patients at increased risk of infection can inform prevention strategies and policy improvements for the coming pandemic waves. Spanish National Health Institute Carlos III Miguel Servet-I - CP17/00206-EU-FEDER EU-FEDER-FIS PI-18/01593 |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2072-6694 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84d5d075ae2904076b8be122f531de3bTest http://hdl.handle.net/10481/68649Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....84d5d075ae2904076b8be122f531de3b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20726694 |
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