المؤلفون: N. Thao N. Galvan, Mercedes Barzi, John A. Goss, William R. Lagor, David D. Moore, Adam Dean, Neil J. McKenna, Pavel Sumazin, Barry Zorman, Diane Yang, Beatrice Bissig-Choisat, Karl-Dimiter Bissig, Xavier Legras, David E. Cohen, Robert Brian York, Malgorzata Borowiak, Michele Alves-Bezerra, Scott A. Ochsner

المصدر: JHEP reports : innovation in hepatology, vol 3, iss 3
JHEP Reports
JHEP Reports, Vol 3, Iss 3, Pp 100281-(2021)

مصطلحات موضوعية: phosphatidylinositol, Cirrhosis, Steatosis, ALT, hexosylceramide, Humanised mice, SREBP, sterol regulatory element-binding protein, PI, RC799-869, CMHs, chimeric mouse hepatocytes, 0302 clinical medicine, GGT, gamma-glutamyl transpeptidase, aspartate aminotransferase, HCC, gamma-glutamyl transpeptidase, chemistry.chemical_classification, 0303 health sciences, education.field_of_study, Western-type diet, Gastroenterology, NASH, CHHs, Diseases of the digestive system. Gastroenterology, 3. Good health, confidence transcript, HCT, cholesteryl ester, human albumin, DCER, dihydroceramide, 030211 gastroenterology & hepatology, PC, non-alcoholic steatohepatitis, PE, transgene-free Il2rg-/-/Rag2-/-/Fah, free fatty acid, LPE, lysophosphatidylethanolamine, DCER, NASH, non-alcoholic steatohepatitis, HCER, hexosylceramide, NC, normal chow, TIRF, PE, phosphatidylethanolamine, nitisinone, lysophosphatidylethanolamine, 03 medical and health sciences, dihydroceramide, Human disease modelling, NAFLD, FFA, free fatty acid, LCER, DEG, MUFA, education, phosphatidylcholine, chimeric mouse hepatocytes, FAH, SM, sphingomyelin, ALP, alkaline phosphatase, FA, fatty acid, NTBC, Fatty acid, medicine.disease, differentially expressed gene, lactosylceramide, PNPLA3, patatin-like-phospholipase domain-containing protein 3, Lipid metabolism, chemistry, fatty acid, PUFA, hALB, human albumin, TIRF, transgene-free Il2rg-/-/Rag2-/-/Fah, AST, aspartate aminotransferase, CT, confidence transcript, PC, phosphatidylcholine, monounsaturated fatty acid, DEG, differentially expressed gene, MUFA, monounsaturated fatty acid, Immunology and Allergy, MAG, monoacylglycerol, PUFA, polyunsaturated free FA, CE, cholesteryl ester, CER, diacylglycerol, FAH, fumarylacetoacetate hydrolase, Fatty liver, SM, chimeric human hepatocytes, hepatocellular carcinoma, CBPEGs, cholesterol biosynthesis pathway enzyme genes, CE, MAG, LPC, patatin-like-phospholipase domain-containing protein 3, triacylglycerol, LPE, alkaline phosphatase, sterol regulatory element-binding protein, Polyunsaturated fatty acid, Research Article, CT, NAFLD, non-alcoholic fatty liver disease, FA, HCER, TAG, triacylglycerol, fumarylacetoacetate hydrolase, monoacylglycerol, alanine aminotransferase, Population, cholesterol biosynthesis pathway enzyme genes, Biology, SREBP, PI, phosphatidylinositol, sphingomyelin, lysophosphatidylcholine, WD, ALT, alanine aminotransferase, high confidence transcriptional target, Internal Medicine, medicine, CBPEGs, ceramide, hALB, LCER, lactosylceramide, normal chow, AST, polyunsaturated free FA, WD, Western-type diet, PNPLA3, 030304 developmental biology, Hepatitis, LPC, lysophosphatidylcholine, Hepatology, DAG, non-alcoholic fatty liver disease, NTBC, nitisinone, CMHs, GGT, HCT, high confidence transcriptional target, phosphatidylethanolamine, TAG, Cancer research, CHHs, chimeric human hepatocytes, ALP, Liver function, NC, CER, ceramide, HCC, hepatocellular carcinoma, FFA, DAG, diacylglycerol, Non-alcoholic fatty liver disease

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b0393a5555874a5526c491b8421dfdTest
https://escholarship.org/uc/item/2hg8h2x9Test

المؤلفون: Julie Rodriguez, Nathalie M. Delzenne, Christelle Knudsen, Audrey M. Neyrinck, Martin Beaumont, Laure B. Bindels

المساهمون: UCL - SSS/LDRI - Louvain Drug Research Institute, Metabolism and Nutrition Research Group, Louvain Drug Research Institute, Université Catholique de Louvain = Catholic University of Louvain (UCL), Génétique Physiologie et Systèmes d'Elevage (GenPhySE ), École nationale supérieure agronomique de Toulouse [ENSAT]-Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Wallonia (FOOD4GUT project) 1318148 / EU 613979 MyNewGut FP7-609398

المصدر: The Proceedings of the Nutrition Society, Vol. 78, no. 3, p. 319-328 (2019)
Proceedings of the Nutrition Society
Proceedings of the Nutrition Society, Cambridge University Press (CUP), 2019, 78 (3), pp.319-328. ⟨10.1017/S0029665118002756⟩

مصطلحات موضوعية: GLP glucagon-like peptide, 0301 basic medicine, non-alcoholic fatty liver desease, Medicine (miscellaneous), Gut flora, Bioinformatics, Mice, GPR G protein-coupled receptors, 0302 clinical medicine, NASH non-alcoholic steatohepatitis, Non-alcoholic Fatty Liver Disease, Nutrition and Dietetics, Fatty liver, 3. Good health, Liver, NAFLD non-alcoholic fatty liver disease, prebiotic, ALT alanine aminotransferase, 030211 gastroenterology & hepatology, medicine.symptom, ITF inulin-type fructans, [SDV.OT]Life Sciences [q-bio]/Other [q-bio.OT], Inflammation, Gut microbiota, Biology, digestive system, 03 medical and health sciences, BA bile acid, medicine, Animals, Humans, gut microbiota, Host (biology), Probiotics, FXR farnesoid X receptor, AST aspartate aminotransferase, Metabolism, medicine.disease, biology.organism_classification, Obesity, Gastrointestinal Microbiome, Disease Models, Animal, Prebiotics, 030104 developmental biology, AhR aryl hydrocarbon receptor, inflammation, LPS lipopolysaccharides, Farnesoid X receptor, Energy Metabolism, Function (biology), Non-alcoholic fatty liver disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e56d9d5d0ddd04fa33e558922e0d67Test
https://doi.org/10.1017/s0029665118002756Test

المؤلفون: Montserrat Marí, José C. Fernández-Checa, Anna Colell, Albert Morales, Carmen García-Ruiz

المصدر: Redox Biology, Vol 3, Iss C, Pp 100-108 (2014)
Redox Biology
Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: Alcoholic liver disease, OXPHOS, oxidative phosphorylation, Clinical Biochemistry, Mitochondria, Liver, Mitochondrial GSH, Mitochondrion, medicine.disease_cause, Biochemistry, AH, alcoholic hepatitis, 0302 clinical medicine, GSH, glutathione, FFA, free fatty acids, Acid sphingomyelinase, TNF, tumor necrosis factor, lcsh:QH301-705.5, 0303 health sciences, lcsh:R5-920, CYP2E1, cytochrome P450 2E1, ASMase, acid sphingomyelinase, TG, triglycerides, Endoplasmic Reticulum Stress, Glutathione, 3. Good health, Cell biology, MRC, mitochondrial respiratory chain, Mitochondrial cholesterol, Cholesterol, Sphingomyelin Phosphodiesterase, Mitochondrial respiratory chain, ASH, alcoholic steatohepatitis, Lipotoxicity, 030211 gastroenterology & hepatology, ER stress, lcsh:Medicine (General), Research Paper, medicine.medical_specialty, ALD, alcoholic liver disease, mGSH, mitochondrial GSH, SH, steatohepatitis, NASH, non-alcoholic steatohepatitis, Oxidative phosphorylation, Biology, ER, endoplasmic reticulum, 03 medical and health sciences, ROS, reactive oxygen species, SOD, superoxide dismutase, Internal medicine, medicine, Animals, Humans, Liver Diseases, Alcoholic, 030304 developmental biology, Endoplasmic reticulum, Organic Chemistry, medicine.disease, Endocrinology, lcsh:Biology (General), Unfolded protein response, NAFLD, nonalcoholic fatty liver disease, Reactive Oxygen Species, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef38e86f50b5350b0acad0cb4e609e11Test
http://www.sciencedirect.com/science/article/pii/S2213231714001049Test

المؤلفون: Irene Locatelli, Francesco Vizzutti, N. Navari, Emanuele Albano, Alessandra Caligiuri, Erica Novo, Maurizio Parola, Massimo Pinzani, W. Delogu, E. Zamara, Fabio Marra, Salvatore Sutti, S. Galastri, E. Vivoli, A. Provenzano, Stefano Milani

المصدر: Clinical Science (London, England : 1979)
Clinical Science
Clinical Science; Vol 123

مصطلحات موضوعية: Liver Cirrhosis, HNE, 4-hydroxynonenal, IFN-γ, interferon-γ, Adipose tissue, AST, aspartate aminotransferase, iNOS, inducible NO synthase, chemistry.chemical_compound, Mice, 0302 clinical medicine, CC chemokine ligand 2, Fibrosis, Transforming Growth Factor beta, cytokine, Chemokine CCL2, liver fibrosis, Mice, Knockout, 0303 health sciences, TIMP-1, tissue inhibitor of metalloproteinases-1, Mice, Inbred BALB C, Fatty liver, CCL2, CC chemokine ligand 2, General Medicine, MGL1, macrophage galactose-type C-type lectin 1, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, TNFα, tumour necrosis factor α, 030211 gastroenterology & hepatology, non-alcoholic steatohepatitis, Research Article, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, ALT, alanine transaminase, NASH, non-alcoholic steatohepatitis, Biology, S2, Collagen Type I, 03 medical and health sciences, ROS, reactive oxygen species, Species Specificity, Internal medicine, TGF-β, transforming growth factor-β, medicine, Hepatic Stellate Cells, Animals, Sirius Red, 030304 developmental biology, KO, knockout, Tissue Inhibitor of Metalloproteinase-1, Macrophages, chemokine, medicine.disease, WT, wild-type, Dietary Fats, IL, interleukin, Fatty Liver, Mice, Inbred C57BL, Disease Models, Animal, Oxidative Stress, Endocrinology, chemistry, Alanine transaminase, Immunology, CCR2, CC chemokine receptor 2, Hepatic stellate cell, biology.protein, Steatosis, Steatohepatitis, RT, real-time, FAM, 6-carboxyfluorescein, MCD diet, methionine/choline-deficient diet

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6301da5ba54f78553e0c47b589df9625Test
http://europepmc.org/articles/PMC3369401Test

المؤلفون: Emina Halilbasic, Thierry Claudel, Michael Trauner

المصدر: Journal of Hepatology
Journal of Hepatology; Vol 58

مصطلحات موضوعية: ABCG5/8, cholesterol efflux pump, ATP-binding cassette, subfamily G, member 5/8, NTCP (SLC10A1), sodium/taurocholate cotransporting polypeptide, solute carrier family 10, member 1, TGR5, G protein-coupled bile acid receptor, Receptors, Cytoplasmic and Nuclear, Review, Mdr2/MDR3 (ABCB4), multidrug resistance protein 2 (rodents)/3 (human), MRP4 (ABCC4), multidrug resistance-associated protein 4, ATP-binding cassette, subfamily C, member 4, Intestinal absorption, 0302 clinical medicine, RXRα (NR2B1), retinoid X receptor alpha, PFIC, progressive familial intrahepatic cholestasis, FXR (NR1H4), farnesoid X receptor/bile acid receptor, AE2, anion exchanger 2, LCA, lithocholic acid, VDR (NR1I1), vitamin D receptor. Please note that for the convenience of better readability and clarity, abbreviations for transporters and nuclear receptors were capitalized throughout this article when symbols were identical for human and rodents, 0303 health sciences, OATP1B3 (SLCO1B3, OATP8, SLC21A8), solute carrier organic anion transporter family, member 1B3, Cholestasis, Membrane Glycoproteins, BCRP (ABCG2), breast cancer resistance protein, ATP-binding cassette, subfamily G, member 2, BRIC, benign recurrent intrahepatic cholestasis, Bile acid, Liver Diseases, Progressive familial intrahepatic cholestasis, NR, nuclear receptor, FGF15/19, fibroblast growth factor 15/19, G protein-coupled bile acid receptor, GLP-1, glucagon like peptide 1, MRP3 (ABCC3), multidrug resistance-associated protein 3, ATP-binding cassette, subfamily C, member 3, Ursodeoxycholic acid, 3. Good health, RARα (NR1B1), retinoic acid receptor alpha, TNFα, tumor necrosis factor α, Biochemistry, Liver, FGF15/19, BA, bile acid, CAR (NR1I3), constitutive androstane receptor, 030211 gastroenterology & hepatology, medicine.drug, NAFLD, non-alcoholic fatty liver disease, PXR (NR1I2), pregnane X receptor, medicine.drug_class, PH, partial hepatectomy, IL6, interleukin 6, NASH, non-alcoholic steatohepatitis, 6-ECDCA, 6-ethylchenodeoxycholic acid, LXRα (NR1H3), liver X receptor alpha, Biology, MRP2 (ABCC2), multidrug resistance-associated protein 2, ATP-binding cassette, subfamily C, member 2, UDCA, ursodeoxycholic acid, Bile Acids and Salts, 03 medical and health sciences, medicine, Animals, Humans, ICP, intrahepatic cholestasis of pregnancy, MDR1 (ABCB1), p-glycoprotein, ATP-binding cassette, subfamily B, member 1, 030304 developmental biology, GR (NR3C1), glucocorticoid receptor, TPN, total parenteral nutrition, Hepatology, Liver receptor homolog-1, BSEP (ABCB11), bile salt export pump, HNF1α, hepatocyte nuclear factor 1 alpha, medicine.disease, LRH-1 (NR5A2), liver receptor homolog-1, Bile acids, OSTαβ, organic solute transporter alpha/beta, Liver Regeneration, EGFR, epidermal growth factor receptor, Bile acids, Cholestasis, Fatty liver disease, Gallstones, Liver regeneration, Liver cancer, norUDCA, norursodeoxycholic acid, PSC, primary sclerosing cholangitis, OATP1B1 (SLCO1B1, OATP2, OATP-C, SLC21A6), solute carrier organic anion transporter family, member 1B1, SRC2, p160 steroid receptor coactivator, PPARα (NR1C1), peroxisome proliferator-activated receptor alpha, AMPK, AMP activated protein kinase, SHP (NR0B2), short heterodimer partner, OATP1A2 (SLCO1A2, OATP1, OATP-A, SLC21A3), solute carrier organic anion transporter family, member 1A2, PBC, primary biliary cirrhosis, IBABP (FABP6, ILBP), intestinal bile acid-binding protein, fatty acid-binding protein 6, Carrier Proteins, HCC, hepatocellular carcinoma, HNF4α (NR2A1), hepatocyte nuclear factor 4 alpha, PPARγ (NR1C3), peroxisome proliferator-activated receptor gamma

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5e9e0dc14c7aa1eedb7912aef1d18f5Test
https://pubmed.ncbi.nlm.nih.gov/22885388Test