أعرض في EDS

Edoxaban versus warfarin in patients with atrial fibrillation

التفاصيل البيبلوغرافية
العنوان:	Edoxaban versus warfarin in patients with atrial fibrillation
المؤلفون:	Robert P. Giugliano, Christian T. Ruff, Eugene Braunwald, Sabina A. Murphy, Stephen D. Wiviott, Jonathan L. Halperin, Albert L. Waldo, Michael D. Ezekowitz, Jeffrey I. Weitz, Jind?ich ?pinar, Witold Ruzyllo, Mikhail Ruda, Yukihiro Koretsune, Joshua Betcher, Minggao Shi, Laura T. Grip, Shirali P. Patel, Indravadan Patel, James J. Hanyok, Michele Mercuri, Elliott M. Antman, Braunwald E, Antman EM, Giugliano RP, Ruff CT, Morin SE, Hoffman EB, Murphy SA, Deenadayalu N, Grip L, Mercuri M, Lanz H, Patel I, Curt V, Duggal A, Hanyok J, Davé J, Morgan D, Choi Y, Shi M, Jin J, Xie J, Crerand W, Kappelhof J, Maxwell W, Skinner M, Patel S, Betcher J, Selicato G, Otto C. Jr, Reissner C, Smith K, Ostroske J, Ron A, Giugliano R, Connolly S, Camm J, Ezekowitz M, Halperin J, Waldo A, Paolasso E, Aylward P, Heidbuchel H, Nicolau JC, Goudev A, Roy D, Weitz J, Corbalán R, Yang Y, Botero R, Bergovec M, Ŝpinar J, Grande P, Hassager C, Voitk J, Huikuri H, Nieminen M, Blanc JJ, LeHeuzey JY, Mitrovic V, Alexopoulos D, Sotomora G, Kiss R, SomaRaju B, Lewis B, Merlini P, Metra M, Koretsune Y, Yamashita T, García Castillo A, Ophuis T, White H, Atar D, Horna M, Babilonia N, Ruzyllo W, Morais J, Dorobantu M, Ruda M, Ostojic M, Duris T, Dalby A, Chung N, Zamorano JL, Juul Möller S, Moccetti T, Chen SA, Sritara P, Oto A, Parkhomenko A, Senior R, Verheugt F, Skene A, Anderson J, Bauer K, Easton JD, Goto S, Wiviott S, Lowe C, Awtry E, Berger CJ, Croce K, Desai A, Gelfand E, Goessling W, Greenberger NJ, Ho C, Leeman DE, Link MS, Norden AD, Pande A, Rost N, Ruberg F, Silverman S, Singhal A, Vita JA, Vogelmann O, Gonzalez C, Ahuad Guerrero R, Rodriguez M, Albisu J, Rosales E, Allall O, Reguero M, Alvarez C, Garcia M, Ameriso S, Ameriso P, Amuchastegui M, Caceres M, Beloscar J, Petrucci J, Berli M, Budassi N, Valle M, Bustamante Labarta G, Saravia M, Caccavo A, Fracaro V, Cartasegna L, Novas V, Caruso O, Zarandon RS, Colombo H, Morandini M, Cuello J, Rosell M, Cuneo C, Bocanera M, D'Amico A, Cendali G, Dran R, Moreno V, Estol C, Davolos M, Facello A, Facello M, Falu E, Iriarte M, Femenia F, Arrieta M, Fuselli J, Zanotti A, Gant Lopez J, Meiller F, Garcia Duran R, Perlo D, Garrido M, Ceirano C, Giacomi G, Eden M, Giannaula R, Huerta M, Goicoechea R, von Wulffen M, Hominal M, Bianchini M, Jure H, Jure D, Kevorkian R, Monaco F, Lanternier G, Belcuore M, Liniado G, Iglesias M, Litvak B, Nigro A, Llanos J, Vignau S, Lorente C, Shatsky K, Lotti J, Raimondi G, Mackinnon I, Carne M, Manuale O, Calderon M, Marino J, Funes I, Muntaner J, Gandur H, Nul D, Verdini E, Piskorz D, Tommasi A, Povedano G, Casares E, Pozzer D, Fernandez E, Prado A, Venturini C, Ramos H, 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J, Pella D, Fedacko J, Ruffini L, Morsky J, Slanina M, Kmec J, Zachar A, Kokles M, Zareczky P, Bollova D, Badenhorst J, Erasmus L, Basson M, Poynton M, Allman J, Ellis G, Botha L, Engelbrecht J, Mostert M, Essop M, Nunkoo T, Gani M, Wilson L, Kelfkens Y, Mitha I, Taljaard J, Naidoo D, Duki Y, Snyders F, Munnik M, Soma P, Johnston H, van der Merwe N, Goosen Y, van Zyl L, le Roux M, Venter T, Wessels L, Bae HJ, Han MG, Cha JK, Kim DH, Cho BR, Ryu DR, Choi HH, Hong KS, Chung WS, Oh YS, Han SH, Lee KH, Hong TJ, Lee HW, Hyon MS, Jung JW, Jeon HK, Lee JM, Kang DH, Choi KJ, Kim CJ, Jin ES, Kim DS, Seo JS, Kim HS, Cha MJ, Kim JT, Park MS, Kim JH, Park JH, Kim JS, Park SJ, Kim SH, Seo JB, Kim YJ, Chun MY, Lee MH, Joung BY, Lee SH, Shin DG, Namgung J, Kwak JJ, Rha SW, Na JO, Rim SJ, Kim JY, Arcocha Torres M, Rey AM, Blanco Coronado J, Puertas I, Bruguera Cortada J, Cabero P, Calvo C, Calvo G, de Arce Borda A, Asensio A, Diez Tejedor E, Guevara MP, Gonzalez Juanatey J, Moure M, Hernandez Madrid A, Delgado A, Lopez Garcia Aranda V, Barquero R, Manzano L, Abril SB, Merino J, Diaz Pintado M, Arias J, Fernandez M, Alvarez RF, Terns M, Delgado MD, Villuendas R, Astier L, Appelros P, Åkerberg A, Blom KB, Andersson R, Blomström P, Persson L, Carlsson T, Bengtsson AS, Dettmann S, Östberg S, Engdahl J, Karlsson L, Herlitz J, Winberg L, Jernhed H, Koskinen P, Håkansson E, Kozak P, Edlund M, Malmqvist L, Eriksson G, Randers F, Moodh J, Rautio A, Johansson M, Rönn F, Sundholm C, Stenberg A, Gunnarsson A, Thulin J, Broberg M, Slater IP, Cheng CC, Wu WS, Chiang CE, Yu WC, Chiang FT, Wu YW, Chiou CW, Yeh TC, Hsia CH, Chen YP, Huang JL, Chen YF, Kuo CT, Wang CL, Lai WT, Lin TH, Lee JT, Pai PY, Lin KH, Shyu KG, Chiu CZ, Tseng WK, Pan YF, Ueng KC, Lee SC, Wang JH, Tsai WC, Yeh HI, Kuo JY, Jirasirirojanakorn K, Pornchaiyasit K, Kaewsuwanna P, Sinthusopa W, Kiatchoosakun S, Sriprasert S, Laothavorn P, Bamrungpong P, Piyayotai D, Sripracha A, Panpunuan P, Sukonthasarn A, Mekara W, Vorasettakarnkij Y, Puripun E, Acikel M, Akilli H, Demir H, Ata N, Bayata S, Cakmak N, Calik A, Cayli M, Ceyhan C, Erdogan D, Ermis C, Kabul K, Kanadasi M, Turgut O, Tandogan I, Yalcin R, Yigit F, Yigit Z, Zoghi M, Batushkin V, Azhdari M, Bazylevych A, Vlasyuk Z, Bereznyakov I, Lebedynskaya M, Dotsenko S, Kulynych R, Dzyak G, Vasilyeva L, Faynyk A, Sorokivskyy M, Gavrysyuk V, Dzublik Y, Horbach L, Husyev V, Godlevska O, Samburg Y, Karpenko O, Nevolina I, Karpenko Y, Blihar O, Kaydashev I, Gerasimenko N, Kolomyyits S, Vasylets V, Kopytsya M, Petyunina O, Kotseruba V, Dvoieglazova M, Koval V, Ohirko O, Koval' O, Kaplan P, Kraiz I, Usan N, Kraydashenko O, Stets R, Kupnovytska I, Kyyak Y, Lizogub V, Gorna O, Malynovsky Y, Fedotov S, Ostrovska L, Ushakova Sokolova L, Dovgan N, Potapenko P, Nekrasa A, Prokhorov O, Leonidova V, Rebrov B, Gamachek O, Rishko M, Chendey T, Rudyk I, Shatilo V, Ishchuk V, Shcherbak V, Goncharova I, Shvetz N, Zamlynskyy M, Sirenko Y, Stanislavchuk M, Perebetiuk L, Sychov O, Lyzohub S, Tseluyko V, Kuznetsov I, Tykhonova S, Vakaliuk I, Drapchak I, Vatutin M, Sklyanna O, Vizir V, Goncharov O, Volkov V, Serik S, Yagensky A, Nahrebetskyy V, Yena L, Mudruk I, Zharinov O, Logvinov Y, Zhurba S, Shandra T, Aggarwal R, Smith S, Beeton I, Dunn S, Blagden M, Price R, Dougal K, Chapman O, Davies D, Choy A, Duff J, Cohen A, Wilmott R, D'Costa D, Douglas H, Dickinson D, Lie F, Ramasamy V, Lindsay S, Atkinson C, Linker N, Finlayson M, Lip G, Brown R, MacCallum P, Ebano P, MacLeod M, McGhee C, Marazzi P, Jones D, Maxwell T, Isted C, More R, Helliwell L, Moriarty A, Mackin A, Murdoch D, Andrews A, Newby D, Flint L, Pye M, Wright L, Avery D, Young G, Sopher M, Kennard S, Storey R, Bridge C, Turner W, Walker M, Venkataraman A, Gilchrist M, Watkin R, Chung A, Wright A, Wright J, Abi Mansour P, Panella M, Adams K, Lohman J, Adler J, Barash B, Adler P, Reiling S, Beck P, Ahmad A, Hussain A, Ahmadpour H, Lim G, Akhter F, Brubaker S, Alexander J, Genova Peeva E, Aliyar P, Godsey W, Allison J, Biscardi R, Almquist A, MacDonald H, Alsheikh T, Lane B, Amin K, Khetarpal S, Amin M, Persechino F, York T, Arnold T, Shoaf R, Arouni A, Rasmussen L, Attanti S, Strickland S, Aude Y, Cobos D, Awasty V, Baldwin E, Ayesu K, Thompson B, Baine S, Batista M, Baman R, Campbell G, Barber M, Altonen D, Barker T, Faircloth C, Barrington P, Gordon L, Bartkowiak A, Benton J, Beasley R, Hoffman T, Bedoya R, Luis Valdes M, Bedwell N, Craig M, Beinart S, Swaim D, Bensimhon D, Garman V, Berk M, Ibarra M, Bernard J, Eldred R, Bilal B, Preston S, Bilazarian S, Langone L, Bingham S, Antonino M, Block T, Talbot Lawson C, Blonder R, Ensminger E, Bloomberg R, Bloomberg K, Blue B, Vernon M, Borsheim M, Hickenbotham D, Bouchard A, Wade W, Bowden W, Ziegler K, Bradley A, Terry P, Brilakis E, Frey W, Brown H, Triano A, Bybee K, Al Maliky T, Cader C, Morton S, Canaday D, Canosa R, Hartranft E, Caplan J, Jameson L, Carr K, Phan D, Chang M, Hatfield G, Charlat M, Tamayo M, Chaturvedi S, Sawaya K, Ciaramita J, Bagby J, Clapp T, Clay A, McClelland M, Dutka C, Cohen R, Bossaers J, Colan D, Salpas S, Cole J, Fisher M, Concha M, Martinez E, Corbett B, Svadbik L, Cossu S, Mullinax K, Cottiero R, Masson E, Cowan L, Nelson L, Curtis B, Sarpola N, Dang N, Morgan T, Daniels S, Leka G, Datta S, Wulf A, Dave K, Dave B, Davuluri A, Ebreo N, De Lemos J, Debes C, Dean J, Warmack D, DeGarmo R, Carey J, Steward A, Desire A, Waters L, Devenport S, Briscoe C, Dhar S, Ucik S, DiGiovanna M, Tisdale L, Donovan D, Rodriguez L, Dotani I, Olson A, Drozdiak R, Habibi S, D'Souza A, Cullen T, Eade J, Dunn K, Eldadah Z, Quick R, Ellis J, Cristaldi J, Erenrich N, Johnson C, O'Brien J, Ettinger N, Shipp A, Everhart B, DeSalle D, Fahmy R, Watkins D, Feld L, Tameron A, Feldman J, Tang N, Felten W, Prior J, Fialkow J, Calvo M, Finkel M, Shriver D, Finkelstein S, Fischell T, Drew B, Fishbein G, Donahue S, Flores E, Slayton C, Forman S, Solis A, Frais M, Thrope C, Franco M, Gentry P, French W, Morales C, Friedlander I, Gaffney M, Jones J, Garb J, Miranda J, George F, Valentine H, Gerber J, Hinchion N, Gillespie E, Keane Richmond P, Gogia H, Ewing B, Goldscher D, Latteri J, Goldstein M, Gowda S, Rafala E, Graham S, Bonora M, Griffin S, Aull L, Griffin J, Goodman V, Grossman C, Davis A, Grove D, Mabe K, Guarino J, Gabela W, Guarnieri T, Guerrero, Foster B, Guthrie R, Felsman D, Gvora T, McLean R, Hack T, Morelli L, Hamroff G, Bentivenga L, Han M, Cavanna L, Harris J, Bobade M, Hearne S, Krater C, Heiman M, Dandekar U, Shah D, Henderson D, Millard D, Henry S, Harkins V, Hermany P, Batchell K, Herrod J, Miranda D, Herson S, Carey G, Hinchman D, Vieira P, Hippert R, Dutter S, Hoekstra J, Homan J, Homayouni A, Horton K, Sloss D, Hotchkiss D, Turner N, Houchin V, Howard V, Hays D, Howard L, Craft D, Huang P, Truva C, Hunter J, Battistelli E, Hurst P, Garza M, Hussain M, Tambawala M, Ison R, Butcher S, Jardula M, Andresen T, Johnson F, Phillips T, Jones R, Hughett G, Jovin I, Nichols M, Judson P, Royes A, Kahn B, Coombs V, Kai W, Dugal J, Kandath D, Kostedt G, Kaplan K, Cook S, Kapoor A, Ruggiero M, Karunaratne H, Behm K, Kastelic R, Davis C, Keller R, Keller J, Kerkering M, Bartholomaus D, Kersh R, Buhler A, Kesselbrenner M, DiCorcia L, Khan B, Binns M, Khan M, Khan G, Kindman L, Averett P, Korpas D, Godfrey C, Kotha P, Sanchez E, Kozlowski J, Watts S, Krichmar P, Marquez D, Laliotis A, Jauregui V, Lambert C, Coyle GS, Landau C, Ferguson D, Lang J, Simmons T, Langevin E, Faucett S, Ledbetter L, Royse H, Lentz M, Smith D, Lesser M, Hartley L, Lewis D, Bonds C, Lillestol M, Miller D, Ling L, Murphy R, Littlefield R, Wofford E, Lomnitz D, Lone B, Davids M, Looby R, Ault S, Lui H, Wright H, Lurie M, Edelstein J, Macomber J, Bush D, Magee A, Doctor A, Mainigi S, Lisiecki B, Makam S, Casas R, Mandviwala M, Marar I, Rabadi Marar D, Marenberg M, Bedenko E, Massin E, Hicks T, McCartney M, Stubbs L, McGarvey J, Schwarz L, McGuire K, McKenzie M, Rodkey K, McKnight T, Paul J, McLaurin B, Lack A, Mega J, Marti J, Meholick A, Skinner J, Mehrle A, Wall J, Mendelson R, Cervellione K, Mercado A, Cajulis C, Michlin B, Romero Colon J, Milas J, Sanders D, Miller R, Sanchez S, Miller S, Gryczan J, Mody F, Strugatsky S, Moran J, Garner S, Morledge J, Bowman B, Mouhaffel A, Parrott N, Mounsey P, Schuler C, Mowdy M, Todd S, Mullen P, Raziano S, Murphy A, Oehmann V, Nadar V, Parker A, Naidu J, West M, Nallasivan M, Goza J, Nguyen T, Nomanee S, Nielsen R, Wilmot M, Oberoi M, Thakkar N, Oppenheimer K, McCormick J, Orchard R, Garcia L, Osborne J, Gonzalez M, Oza S, Joseph L, Patnam S, Dennison K, Pavon H, Gorry N, Pearlstein R, Montayne S, Pentz W, Duncan D, Peters P, Chacon L, Petruzziello F, Morlando F, Pettis K, Brown F, Pezzella S, Kirk D, Poulathas A, Cush S, Pratt R, Neeper L, Pribble A, Lowe K, Pudi K, Sham L, Pugeda J, Ebert J, Quadrel M, Rafla E, Quinlan E, Reed C, Quinn J, Hemmen C, Rama P, Domingo D, Redondo V, Wroblewski J, Renzi M, Stanley E, Richwine R, Pazier P, Riofrio K, Braun D, Robinson J, Cherrico M, Roehll W, Hollihan P, Rosado, Barnhorst M, Rosado J, Bamhorst M, Rosen R, Martin C, Ross S, Freeman R, Ruoff G, Nelson T, Sacco J, Ball E, Samal A, Schomburg J, Sandberg J, Lafave J, Savin V, Clifton R, Schaefer S, Fekete A, Schneider R, Schneider W, Schulman D, Mercer S, Seals A, Ullig T, Holt A, Seide H, Mather N, Shah G, Witt P, Shalaby A, Seese M, Shanes J, Fleets J, Shaoulian E, Hren A, Sheikh K, Hengerer T, Shih H, Browning J, Shoukfeh M, Stephenson L, Siler T, Champagne M, Simpson P, Meyer R, Singh N, Turner K, Singh V, Nelson M, Skierka R, Hughes B, Keene R, Smith R, Hodnett P, Spangenthal S, Thomason L, Sperling M, Vasquez E, Spivack E, McCartney P, Staniloae C, Liu M, Steljes A, Cox C, Struble R, Vittitow T, Suresh D, Frost J, Swerchowsky V, Freemyer D, Szulawski I, Herwehe S, Tahirkheli N, Springer K, Takata T, Bruton T, Talano J, Leo L, Tami L, Corchado D, Tatarko M, Swauger M, Tawney K, Dastoli K, Teague S, Young K, Tee H, Mitchell T, Teixeira J, Southam D, Torres M, Tucker P, Salas L, Updegrove J, Hanna K, Val Mejias J, Harrelson KG, Vemireddy D, Cardoza T, Verma S, Parsons T, Vicari R, Warren K, Vijay N, Washam M, Vossler M, Kilcup S, Walsh R, Renaud K, Ward S, Locklear T, Waxman F, Sanchez G, Weiss R, St Laurent B, Westcott J, Williams D, Gibson C, Williams R, Dowling C, Willis J, VonGerichten S, Wood K, Capasso Gulve E, Worley S, Pointer S, Yarows S, Sheehan T, Yasin M, Yi J, Dongas B, Yousuf K, Zakhary B, Curtis S, Zeig S, Mason T, Zellner C, Harden M, Roper E, Waseem M, Grammer M., PERRONE FILARDI, PASQUALE
المساهمون:	Cardiovascular Division (SZG), Brigham and Women's Hospital [Boston], Mount Sinai Medical Center, Icahn School of Medicine at Mount Sinai [New York] (MSSM), University Hospitals Case Medical Center (CLEVELAND - UHCMC), University Hospitals Case Medical Center, Jefferson Medical College (JMC), Thomas Jefferson University Hospitals, Thrombosis and Atherosclerosis Research Institute (TARI), McMaster University [Hamilton, Ontario], University Hospital Brno, Institute of Cardiology (WARSAW - Cardiology), Institute of Cardiology, Cardiology Research Center (MOSCOU - CRC), Cardiology Research Center, National Hopital Organization (OSAKA - NHO), Osaka National Hospital, Université de Brest (UBO), Centre d'Investigation Clinique (CIC - Brest), Université de Brest (UBO)-Institut National de la Santé et de la Recherche Médicale (INSERM), Graduate School, Endocrinology, ACS - Amsterdam Cardiovascular Sciences, Cardiology, Nursing, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, General Internal Medicine, Giugliano, Rp, Ruff, Ct, Braunwald, E, Murphy, Sa, Wiviott, Sd, Halperin, Jl, Waldo, Al, Ezekowitz, Md, Weitz, Ji, Špinar, J, Ruzyllo, W, Ruda, M, Koretsune, Y, Betcher, J, Shi, M, Grip, Lt, Patel, Sp, Patel, I, Hanyok, Jj, Mercuri, M, Antman, Em, Comi, Giancarlo, ENGAGE AF TIMI 48, Investigators, Robert P., Giugliano, Christian T., Ruff, Eugene, Braunwald, Sabina A., Murphy, Stephen D., Wiviott, Jonathan L., Halperin, Albert L., Waldo, Michael D., Ezekowitz, Jeffrey I., Weitz, Jind?ich, ?pinar, Witold, Ruzyllo, Mikhail, Ruda, Yukihiro, Koretsune, Joshua, Betcher, Minggao, Shi, Laura T., Grip, Shirali P., Patel, Indravadan, Patel, James J., Hanyok, Michele, Mercuri, Elliott M., Antman, Morin, Se, Hoffman, Eb, Deenadayalu, N, Grip, L, Lanz, H, Curt, V, Duggal, A, Hanyok, J, Davé, J, Morgan, D, Choi, Y, Jin, J, Xie, J, Crerand, W, Kappelhof, J, Maxwell, W, Skinner, M, Patel, S, Selicato, G, Otto C., Jr, Reissner, C, Smith, K, Ostroske, J, Ron, A, Giugliano, R, Connolly, S, Camm, J, Ezekowitz, M, Halperin, J, Waldo, A, Paolasso, E, Aylward, P, Heidbuchel, H, Nicolau, Jc, Goudev, A, Roy, D, Weitz, J, Corbalán, R, Yang, Y, Botero, R, Bergovec, M, Ŝpinar, J, Grande, P, Hassager, C, Voitk, J, Huikuri, H, Nieminen, M, Blanc, Jj, Leheuzey, Jy, Mitrovic, V, Alexopoulos, D, Sotomora, G, Kiss, R, Somaraju, B, Lewis, B, Merlini, P, Metra, M, Yamashita, T, García Castillo, A, Ophuis, T, White, H, Atar, D, Horna, M, Babilonia, N, Morais, J, Dorobantu, M, Ostojic, M, Duris, T, Dalby, A, Chung, N, Zamorano, Jl, Juul Möller, S, Moccetti, T, Chen, Sa, Sritara, P, Oto, A, Parkhomenko, A, Senior, R, Verheugt, F, Skene, A, Anderson, J, Bauer, K, Easton, Jd, Goto, S, Wiviott, S, Lowe, C, Awtry, E, Berger, Cj, Croce, K, Desai, A, Gelfand, E, Goessling, W, Greenberger, Nj, Ho, C, Leeman, De, Link, M, Norden, Ad, Pande, A, Rost, N, Ruberg, F, Silverman, S, Singhal, A, Vita, Ja, Vogelmann, O, Gonzalez, C, Ahuad Guerrero, R, Rodriguez, M, Albisu, J, Rosales, E, Allall, O, Reguero, M, Alvarez, C, Garcia, M, Ameriso, S, Ameriso, P, Amuchastegui, M, Caceres, M, Beloscar, J, Petrucci, J, Berli, M, Budassi, N, Valle, M, Bustamante Labarta, G, Saravia, M, Caccavo, A, Fracaro, V, Cartasegna, L, Novas, V, Caruso, O, Zarandon, R, Colombo, H, Morandini, M, Cuello, J, Rosell, M, Cuneo, C, Bocanera, M, D'Amico, A, Cendali, G, Dran, R, Moreno, V, Estol, C, Davolos, M, Facello, A, Facello, M, Falu, E, Iriarte, M, Femenia, F, Arrieta, M, Fuselli, J, Zanotti, A, Gant Lopez, J, Meiller, F, Garcia Duran, R, Perlo, D, Garrido, M, Ceirano, C, Giacomi, G, Eden, M, Giannaula, R, Huerta, M, Goicoechea, R, von Wulffen, M, Hominal, M, Bianchini, M, Jure, H, Jure, D, Kevorkian, R, Monaco, F, Lanternier, G, Belcuore, M, Liniado, G, Iglesias, M, Litvak, B, Nigro, A, Llanos, J, Vignau, S, Lorente, C, Shatsky, K, Lotti, J, Raimondi, G, Mackinnon, I, Carne, M, Manuale, O, Calderon, M, Marino, J, Funes, I, Muntaner, J, Gandur, H, Nul, D, Verdini, E, Piskorz, D, 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المصدر:	New England Journal of Medicine New England Journal of Medicine, Massachusetts Medical Society, 2013, 369 (22), pp.2093-104. ⟨10.1056/NEJMoa1310907⟩ New England journal of medicine, 369(22), 2093-2104. Massachussetts Medical Society The New England Journal of Medicine, 369, 2093-104 The New England Journal of Medicine, 369, 22, pp. 2093-104
سنة النشر:	2013
مصطلحات موضوعية:	Male, Pyridines, [SDV]Life Sciences [q-bio], Embolism, Kaplan-Meier Estimate, 030204 cardiovascular system & hematology, chemistry.chemical_compound, 0302 clinical medicine, Edoxaban, Atrial Fibrillation, MESH: Double-Blind Method, 030212 general & internal medicine, MESH: Warfarin, Stroke, MESH: Aged, MESH: Middle Aged, Cardiovascular diseases [NCEBP 14], Hazard ratio, General Medicine, MESH: Follow-Up Studies, Middle Aged, 3. Good health, MESH: Atrial Fibrillation, Cardiovascular Diseases, Anesthesia, Cardiology, Female, Adult, Aged, Anticoagulants, Double-Blind Method, Follow-Up Studies, Hemorrhage, Humans, Thiazoles, Warfarin, MESH: Hemorrhage, Andexanet alfa, medicine.drug, medicine.medical_specialty, MESH: Enoxaparin, MESH: Anticoagulants, MESH: Stroke, Dabigatran, 03 medical and health sciences, Internal medicine, medicine, MESH: Kaplan-Meier Estimate, Rivaroxaban, MESH: Humans, business.industry, MESH: Cardiovascular Diseases, MESH: Adult, medicine.disease, Confidence interval, MESH: Male, chemistry, business, MESH: Female, MESH: Embolism
الوصف:	Contains fulltext : 125374.pdf (Publisher’s version ) (Open Access) BACKGROUND: Edoxaban is a direct oral factor Xa inhibitor with proven antithrombotic effects. The long-term efficacy and safety of edoxaban as compared with warfarin in patients with atrial fibrillation is not known. METHODS: We conducted a randomized, double-blind, double-dummy trial comparing two once-daily regimens of edoxaban with warfarin in 21,105 patients with moderate-to-high-risk atrial fibrillation (median follow-up, 2.8 years). The primary efficacy end point was stroke or systemic embolism. Each edoxaban regimen was tested for noninferiority to warfarin during the treatment period. The principal safety end point was major bleeding. RESULTS: The annualized rate of the primary end point during treatment was 1.50% with warfarin (median time in the therapeutic range, 68.4%), as compared with 1.18% with high-dose edoxaban (hazard ratio, 0.79; 97.5% confidence interval [CI], 0.63 to 0.99; P
وصف الملف:	STAMPA; application/pdf
تدمد:	0028-4793 1533-4406
الوصول الحر:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f49737d1cd205d6a7d43aceda31f2472Test https://doi.org/10.1056/nejmoa1310907Test
حقوق:	OPEN
رقم الانضمام:	edsair.doi.dedup.....f49737d1cd205d6a7d43aceda31f2472
قاعدة البيانات:	OpenAIRE

الوصف
تدمد:	00284793 15334406