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المؤلفون: Elena Kostromina, Christoffer Nord, Tomas Alanentalo, Federico Morini, Per Olof Berggren, Yan Xiong, Erwin Ilegems, Jürgen Mayer, Pim P van Krieken, James Sharpe, Ulf Ahlgren, Teresa Pereira, Maria Eriksson, Jorge L. Ruas, Max Hahn
المصدر: Communications Biology, Vol 3, Iss 1, Pp 1-14 (2020)
Communications Biologyمصطلحات موضوعية: Male, 0301 basic medicine, endocrine system diseases, Cell- och molekylärbiologi, Cell, Medicine (miscellaneous), Optical imaging, Mice, 0302 clinical medicine, 3-D reconstruction, Insulin-Secreting Cells, Insulin, lcsh:QH301-705.5, Glucose Transporter Type 2, Microscopy, Confocal, geography.geographical_feature_category, biology, Diabetes, Islet, Experimental models of disease, Mechanisms of disease, medicine.anatomical_structure, Endokrinologi och diabetes, General Agricultural and Biological Sciences, medicine.drug, endocrine system, medicine.medical_specialty, Down-Regulation, 030209 endocrinology & metabolism, Endocrinology and Diabetes, Article, General Biochemistry, Genetics and Molecular Biology, Diabetes Mellitus, Experimental, Islets of Langerhans, 03 medical and health sciences, Microscopy, Electron, Transmission, Downregulation and upregulation, Internal medicine, Diabetes mellitus, medicine, Animals, geography, Glucose transporter, nutritional and metabolic diseases, medicine.disease, Streptozotocin, Mice, Inbred C57BL, Transplantation, 030104 developmental biology, Endocrinology, Microscopy, Fluorescence, lcsh:Biology (General), biology.protein, GLUT2, Cell and Molecular Biology, Biomarkers
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba990408233453663d8fd8eb4c76959Test
http://link.springer.com/article/10.1038/s42003-020-01243-2Test -
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المؤلفون: Barbara Leibiger, Stefan Jacob, Tomas Alanentalo, Martin Köhler, Montse Visa, Tilo Moede, Per Olof Berggren, Philip Tröster, Ingo B. Leibiger, Concha F. García-Prieto
المصدر: The FASEB Journal
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Population, Context (language use), Biochemistry, 03 medical and health sciences, 0302 clinical medicine, In vivo, Internal medicine, Genetics, medicine, Glucose homeostasis, education, Molecular Biology, education.field_of_study, geography, geography.geographical_feature_category, Chemistry, Pancreatic islets, Islet, In vitro, 3. Good health, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, 030217 neurology & neurosurgery, Preclinical imaging, Biotechnology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f87522c9c8363f3c1c243d30b4dacc5fTest
https://doi.org/10.1096/fj.201901302rrTest -
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المؤلفون: Ulf Ahlgren, Stefanie M. A. Willekens, Max Hahn, Tomas Alanentalo
المصدر: Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 12 (2021)مصطلحات موضوعية: 0301 basic medicine, Computer science, Endocrinology, Diabetes and Metabolism, Mini Review, Endocrinology and Diabetes, lcsh:Diseases of the endocrine glands. Clinical endocrinology, Optical projection tomography, 03 medical and health sciences, 0302 clinical medicine, Optical imaging, Endocrinology, Imaging, Three-Dimensional, medicine, Humans, Tomography, Optical, Computational analysis, mesoscopic imaging, pancreas, optical projection tomography, light sheet fluorescence microscopy, Pancreas, Mesoscopic physics, lcsh:RC648-665, Cellular composition, diabetes, Low resolution, Optical Imaging, Anatomy, 030104 developmental biology, medicine.anatomical_structure, Microscopy, Fluorescence, Light sheet fluorescence microscopy, Endokrinologi och diabetes, 030217 neurology & neurosurgery
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::307a2bb6991c304d8f30cd5ea3eea8a8Test
https://pubmed.ncbi.nlm.nih.gov/33746904Test -
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المؤلفون: Tomas Alanentalo, Nils Langeland Johansen, Jens Buchardt, Knud Vad, Peter Thygesen, Prafull S. Gandhi, Johannes Josef Fels, Maj Petersen, Peter Helding-Kvist
المصدر: International Journal of Molecular Sciences, Vol 21, Iss 4, p 1181 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 4مصطلحات موضوعية: Male, Models, Molecular, 0301 basic medicine, Fluorescence-lifetime imaging microscopy, Growth hormone receptor, Rats, Sprague-Dawley, lcsh:Chemistry, Mice, Pharmaceutical Sciences, 0302 clinical medicine, Tissue Distribution, lcsh:QH301-705.5, Cells, Cultured, Spectroscopy, Chemistry, General Medicine, Human serum albumin, Computer Science Applications, proximal epiphysis, human growth hormone, Female, medicine.drug, medicine.medical_specialty, Biodistribution, receptor signaling, Mice, Nude, 030209 endocrinology & metabolism, Article, Catalysis, Inorganic Chemistry, 03 medical and health sciences, In vivo, Internal medicine, P-STAT5 activation, medicine, Animals, Humans, Distribution (pharmacology), fluorescence molecular tomography, Physical and Theoretical Chemistry, Molecular Biology, biodistribution, Organic Chemistry, Isothermal titration calorimetry, Receptors, Somatotropin, Farmaceutiska vetenskaper, light-sheet fluorescence microscopy, 030104 developmental biology, Endocrinology, lcsh:Biology (General), lcsh:QD1-999, somapacitan, p-stat5 activation, Hepatocytes, Ex vivo
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7858fd82c1582eb0b5f986f6b7db2a5fTest
https://www.mdpi.com/1422-0067/21/4/1181Test -
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المؤلفون: Sanaz, Gabery, Casper G, Salinas, Sarah J, Paulsen, Jonas, Ahnfelt-Rønne, Tomas, Alanentalo, Arian F, Baquero, Stephen T, Buckley, Erzsébet, Farkas, Csaba, Fekete, Klaus S, Frederiksen, Hans Christian C, Helms, Jacob F, Jeppesen, Linu M, John, Charles, Pyke, Jane, Nøhr, Tess T, Lu, Joseph, Polex-Wolf, Vincent, Prevot, Kirsten, Raun, Lotte, Simonsen, Gao, Sun, Anett, Szilvásy-Szabó, Hanni, Willenbrock, Anna, Secher, Lotte Bjerre, Knudsen, Wouter Frederik Johan, Hogendorf
المصدر: JCI Insight
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Glucagon-Like Peptides, Hindbrain, Biology, Glucagon-Like Peptide-1 Receptor, 03 medical and health sciences, Eating, Mice, 0302 clinical medicine, Internal medicine, Neural Pathways, medicine, Animals, Lateral parabrachial nucleus, Circumventricular organs, Tyrosine hydroxylase, Semaglutide, Area postrema, digestive, oral, and skin physiology, Body Weight, Brain, General Medicine, Rats, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Hypothalamus, 030220 oncology & carcinogenesis, Brainstem, Energy Metabolism, Research Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5006d9b7db3d895b39c5ce61e76405Test
https://pubmed.ncbi.nlm.nih.gov/32213703Test -
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المؤلفون: Kim G. Madsen, Flemming L. Søndergaard, Jonas Ahnfelt-Rønne, Andrew J. Benie, Simon Bjerregaard, Jeanett Borregaard, Tine A. Bækdal, Betty Lomstein Pedersen, Susanne Schéele, Charles Pyke, Marie-Louise Hartoft-Nielsen, Stephen T. Buckley, Tomas Alanentalo, Rikke Bjerring Skyggebjerg, Rikke Kaae Kirk, Lotte Bjerre Knudsen, Stine J. Maarbjerg, Holger M. Strauss, Andreas Vegge, Csaba Fekete, Erzsébet Farkas, Per-Olof Wahlund
المصدر: Science Translational Medicine. 10
مصطلحات موضوعية: Adult, Male, Absorption (pharmacology), Time Factors, Adolescent, Glucagon-Like Peptides, Administration, Oral, 02 engineering and technology, Pharmacology, 030226 pharmacology & pharmacy, Glucagon-Like Peptide-1 Receptor, Intestinal absorption, Young Adult, 03 medical and health sciences, Dogs, 0302 clinical medicine, Glucagon-Like Peptide 1, Oral administration, Animals, Humans, Transcellular, Glucagon-like peptide 1 receptor, Aged, Tight junction, Chemistry, Semaglutide, Cell Membrane, Stomach, Proteolytic enzymes, Epithelial Cells, General Medicine, Hydrogen-Ion Concentration, Middle Aged, 021001 nanoscience & nanotechnology, Rats, Intestinal Absorption, Gastric Mucosa, 0210 nano-technology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da23aec5d09c52d95e43b0ca9e999cdbTest
https://doi.org/10.1126/scitranslmed.aar7047Test -
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المؤلفون: Rasmus Wernersson, Fredrik Wolfhagen Sand, Charlotte Helgstrand, Kevin Dalgaard, Jacob Hald, Anne Grapin-Botton, Sven Hastrup, Thomas Frogne, Jonas Ahnfelt-Rønne, Ole D. Madsen, Lena Hansson, Erik Vernet, Mark Kalisz, Dennis Madsen, Tomas Alanentalo, Mads Grønborg, Maja Borup Kjær Petersen, Fredrik Kryh Öberg, Michael Paolo Bastner Sandrini, Annette Plesner, Claude Rescan, Christian Honoré, Philippe Ravassard, Carsten Jessen, Louise Winkel, Camilla Ingvorsen, Xenia Asbæk Wolf, Hanni Willenbrock, Jan N. Jensen, Anna Kirstine Ringgaard, Christine Bruun, Violeta Georgieva Tsonkova, Jacob Hecksher-Sørensen, Johannes Josef Fels, Lars Groth Grunnet, Allan Christian Shaw
المساهمون: University of Copenhagen = Københavns Universitet (KU), Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute (ICM), Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Molecular metabolism
Molecular metabolism, Elsevier, 2018, 8, pp.144-157. ⟨10.1016/j.molmet.2017.12.007⟩
Molecular Metabolism
Molecular Metabolism, Vol 8, Iss, Pp 144-157 (2018)
Tsonkova, V G, Sand, F W, Wolf, X A, Grunnet, L G, Ringgaard, A K, Ingvorsen, C, Winkel, L, Kalisz, M, Dalgaard, K, Bruun, C, Fels, J J, Helgstrand, C, Hastrup, S, Öberg, F K, Vernet, E, Sandrini, M P B, Shaw, A C, Jessen, C, Grønborg, M, Hald, J, Willenbrock, H, Madsen, D, Wernersson, R, Hansson, L, Jensen, J N, Plesner, A, Alanentalo, T, Petersen, M B K, Grapin-Botton, A, Honoré, C, Ahnfelt-Rønne, J, Hecksher-Sørensen, J, Ravassard, P, Madsen, O D, Rescan, C & Frogne, T 2018, ' The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates ', Molecular Metabolism, vol. 8, pp. 144-157 . https://doi.org/10.1016/j.molmet.2017.12.007Testمصطلحات موضوعية: 0301 basic medicine, [SDV.BIO]Life Sciences [q-bio]/Biotechnology, SI, Stimulation index, medicine.medical_treatment, EndoC-βH1, Proliferation, Cell Culture Techniques, Drug Evaluation, Preclinical, Mice, SCID, CytMix, Cytokine mixture, Mice, 0302 clinical medicine, Insulin-Secreting Cells, Insulin Secretion, Cells, Cultured, Chemistry, Bxv1, B10 xenotropic virus 1, EdU, 5-ethynyl-2′-deoxyuridine, 3. Good health, Cell biology, Cytokine, Original Article, Beta cell, Glucose stimulated insulin secretion, medicine.drug, lcsh:Internal medicine, Somatostatin signaling, Incretin, GSIS, Glucose stimulated insulin secretion, 030209 endocrinology & metabolism, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Cell Line, Diabetes Mellitus, Experimental, 03 medical and health sciences, GLP1R, GLP1 receptor, PACAP, Pituitary Adenylate Cyclase-Activating Polypeptides, medicine, Animals, Humans, Hypoglycemic Agents, Pseudoislets, lcsh:RC31-1245, sXBP1, spliced XBP1, Molecular Biology, IPGTT, Intraperitoneal glucose tolerance test, Insulin, SST, Somatostatin, BB, Bombesin, STZ, Streptozotocin, Cell Biology, Streptozotocin, SSTR, Somatostatin receptor, SEM, Standard error of the mean, 030104 developmental biology, Cell culture, Apoptosis, Unfolded protein response, Ex4, Exendin-4
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb3e641ee305f9db5f81e09f4ed88e7Test
https://hal.sorbonne-universite.fr/hal-02018209/documentTest