Respiratory and Urinary Tract Infections, Arthritis, and Asthma Associated with HTLV-I and HTLV-II Infection
| العنوان: | Respiratory and Urinary Tract Infections, Arthritis, and Asthma Associated with HTLV-I and HTLV-II Infection |
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| المؤلفون: | S Hutching, Bruce Newman, Ronald A. Sacher, Catharie C. Nass, Joy Fridey, Edward L. Murphy, James W. Smith, Baoguang Wang, H.E. Ownby, George B. Schreiber, George Garratty |
| المصدر: | Emerging Infectious Diseases Emerging infectious diseases, vol 10, iss 1 Murphy, EL; Wang, BG; Sacher, RA; Fridey, J; Smith, JW; Nass, CC; et al.(2004). Respiratory and urinary tract infections, arthritis, and asthma associated with HTLV-I and HTLV-II infection. EMERGING INFECTIOUS DISEASES, 10(1), 109-116. doi: 10.3201/eid1001.020714. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/2r43g4xdTest Emerging Infectious Diseases, Vol 10, Iss 1, Pp 109-116 (2004) |
| بيانات النشر: | Centers for Disease Control and Prevention, 2004. |
| سنة النشر: | 2004 |
| مصطلحات موضوعية: | Male, Epidemiology, viruses, lcsh:Medicine, Arthritis, Blood Donors, 0302 clinical medicine, immune system diseases, hemic and lymphatic diseases, Medicine, 030212 general & internal medicine, Prospective Studies, Prospective cohort study, Respiratory Tract Infections, 0303 health sciences, Respiratory tract infections, Incidence, virus diseases, Middle Aged, 3. Good health, Infectious Diseases, Medical Microbiology, Urinary Tract Infections, Public Health and Health Services, HTLV-II Infections, Bronchitis, Female, Microbiology (medical), Adult, Urinary system, Clinical Sciences, Microbiology, lcsh:Infectious and parasitic diseases, 03 medical and health sciences, HIV Seronegativity, Humans, lcsh:RC109-216, Kidney infection, 030306 microbiology, business.industry, Research, lcsh:R, medicine.disease, HTLV-I Infections, Survival Analysis, Asthma, United States, Pneumonia, Immunology, business |
| الوصف: | Human T-lymphotropic virus types I and II (HTLV-I and -II) cause myelopathy; HTLV-I, but not HTLV-II, causes adult T-cell leukemia. Whether HTLV-II is associated with other diseases is unknown. Using survival analysis, we studied medical history data from a prospective cohort of HTLV-I– and HTLV-II–infected and –uninfected blood donors, all HIV seronegative. A total of 152 HTLV-I, 387 HTLV-II, and 799 uninfected donors were enrolled and followed for a median of 4.4, 4.3, and 4.4 years, respectively. HTLV-II participants had significantly increased incidences of acute bronchitis (incidence ratio [IR] = 1.68), bladder or kidney infection (IR = 1.55), arthritis (IR = 2.66), and asthma (IR = 3.28), and a borderline increase in pneumonia (IR = 1.82, 95% confidence interval [CI] 0.98 to 3.38). HTLV-I participants had significantly increased incidences of bladder or kidney infection (IR = 1.82), and arthritis (IR = 2.84). We conclude that HTLV-II infection may inhibit immunologic responses to respiratory infections and that both HTLV-I and -II may induce inflammatory or autoimmune reactions. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1080-6059 1080-6040 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ce7f42489cf5b8d700c343bc794f92Test http://europepmc.org/articles/PMC3322766Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....63ce7f42489cf5b8d700c343bc794f92 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10806059 10806040 |
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