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1
المؤلفون: Melanie Hullings, Ryon P. Graf, Howard I. Scher, Ryan Dittamore, Emily Carbone, Ethan Barnett
المصدر: Eur Urol
مصطلحات موضوعية: Male, Oncology, medicine.medical_specialty, Urology, medicine.medical_treatment, Clinical Decision-Making, 030232 urology & nephrology, Lower risk, Article, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Circulating tumor cell, Internal medicine, Phenylthiohydantoin, medicine, Humans, Liquid biopsy, Chemotherapy, Taxane, business.industry, Neoplastic Cells, Circulating, medicine.disease, Prostatic Neoplasms, Castration-Resistant, Receptors, Androgen, 030220 oncology & carcinogenesis, Cohort, Biomarker (medicine), business, Biomarkers
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d38c7b42df0eb29e3fb1207006f9376fTest
https://doi.org/10.1016/j.eururo.2019.08.020Test -
2
المؤلفون: Arthur E. Frankel, Melanie Hullings, Nisha Unni, Melissa Rodriguez, Thomas W. Froehlich, Dawn Klemow, Kiran Batra, Sunati Sahoo, Barbara Haley, Chul Ahn
المصدر: Clinical breast cancer. 21(5)
مصطلحات موضوعية: 0301 basic medicine, Oncology, Adult, Bridged-Ring Compounds, Cancer Research, medicine.medical_specialty, Maximum Tolerated Dose, Pyridines, Antineoplastic Agents, Breast Neoplasms, Palbociclib, Ado-Trastuzumab Emtansine, Piperazines, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Trastuzumab, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Taxane, business.industry, Cancer, Middle Aged, medicine.disease, 030104 developmental biology, 030220 oncology & carcinogenesis, Neratinib, Toxicity, Female, Taxoids, Pertuzumab, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::666730afbfe1b3f83663ea32957a94b3Test
https://pubmed.ncbi.nlm.nih.gov/33836974Test -
3
المؤلفون: Joseph D. Schonhoft, Angel E. Dago, Ryan Dittamore, Jimmy L. Zhao, Melanie Hullings, Mithat Gonen, Jerry Lee, Ethan Barnett, Adam Jendrisak, Yipeng Wang, Audrey Gill, Emily Carbone, Samuel F. Bakhoum, Mark Landers, Howard I. Scher, Ramsay Sutton
المصدر: Cancer Res
مصطلحات موضوعية: 0301 basic medicine, Genetic Markers, Male, Cancer Research, DNA Copy Number Variations, Cell, Sensitivity and Specificity, Article, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Circulating tumor cell, Chromosome instability, Chromosomal Instability, Biopsy, medicine, Humans, Aged, Aged, 80 and over, medicine.diagnostic_test, business.industry, Reproducibility of Results, Chromosome Breakage, Middle Aged, medicine.disease, Neoplastic Cells, Circulating, Prognosis, High-Throughput Screening Assays, Androgen receptor, Prostatic Neoplasms, Castration-Resistant, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Genomic Structural Variation, Cancer research, Disease Progression, Biomarker (medicine), Chromosome breakage, business, Algorithms
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752bdfef1da6f8dcab84a6c08482f6dfTest
https://pubmed.ncbi.nlm.nih.gov/32816908Test -
4
المؤلفون: Philip W. Kantoff, Wassim Abida, Ethan Barnett, Konrad H. Stopsack, Chloe J. Kim, Melanie Hullings, David B. Solit, Emily Weg, Samuel Haywood, Samantha E. Vasselman, Howard I. Scher, Subhiksha Nandakumar, Bastien Nguyen, Emily Carbone, Nikolaus Schultz, Michael J. Morris, Andreas Wibmer
المصدر: Clin Cancer Res
مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Cancer Research, medicine.medical_specialty, Disease, Kaplan-Meier Estimate, SPOP, Article, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Castration Resistance, Internal medicine, medicine, Biomarkers, Tumor, Humans, Orchiectomy, Aged, Neoplasm Staging, business.industry, Hazard ratio, Wnt signaling pathway, Genetic Variation, Prostatic Neoplasms, Genomics, Oncogenes, Cell cycle, Middle Aged, medicine.disease, Prognosis, 030104 developmental biology, Phenotype, Treatment Outcome, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Neoplasm Grading, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac311e6ba3427642a54d6c52cc588aacTest
https://pubmed.ncbi.nlm.nih.gov/32220891Test -
5
المؤلفون: Susan F. Slovin, Michael J. Morris, Michael L. Cheng, Charles L. Sawyers, Ethan Barnett, Daniel C. Danila, Hebert Alberto Vargas, Jinru Shia, Melanie Hullings, Nikolaus Schultz, Anuradha Gopalan, Vincent P. Laudone, David B. Solit, Jedd D. Wolchok, Karen A. Autio, Philip Jonsson, Michael F. Berger, Wassim Abida, Ahmet Zehir, Howard I. Scher, Barry S. Taylor, Sumit Middha, Preethi Srinivasan, Nicholas D. Socci, Emily Carbone, Joshua Armenia, Zsofia K. Stadler, Victor E. Reuter, Dana E. Rathkopf, Jaclyn F. Hechtman, Philip W. Kantoff
المصدر: JAMA Oncology. 5:471
مصطلحات موضوعية: Adult, Male, Oncology, Cancer Research, medicine.medical_specialty, Programmed Cell Death 1 Receptor, Population, Pembrolizumab, Disease, DNA Mismatch Repair, B7-H1 Antigen, 03 medical and health sciences, Prostate cancer, Antineoplastic Agents, Immunological, 0302 clinical medicine, Germline mutation, Internal medicine, Prevalence, Humans, Medicine, 030212 general & internal medicine, education, Aged, Original Investigation, Aged, 80 and over, education.field_of_study, biology, business.industry, Prostatic Neoplasms, Microsatellite instability, Middle Aged, medicine.disease, Immune checkpoint, Phenotype, Treatment Outcome, 030220 oncology & carcinogenesis, Mutation, biology.protein, Microsatellite Instability, Antibody, business, Biomarkers
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0631220677b3caf11686fdbbb7bb4df1Test
https://doi.org/10.1001/jamaoncol.2018.5801Test -
6
المؤلفون: Dana E. Rathkopf, Gabrielle Arauz, Melanie Hullings, Felix Y. Feng, Karen E. Knudsen, Emmanuel S. Antonarakis, Annelise Slack, Heather H. Cheng, Howard I. Scher, Karen A. Autio
المصدر: Journal of Clinical Oncology. 36:5045-5045
مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, business.industry, Castration resistant, medicine.disease, Clinical trial, 03 medical and health sciences, Prostate cancer, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, chemistry, 030220 oncology & carcinogenesis, Internal medicine, medicine, Enzalutamide, business, PI3K/AKT/mTOR pathway
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::0f174b19285d0b3cc55b1bff0d41ab2aTest
https://doi.org/10.1200/jco.2018.36.15_suppl.5045Test -
7
المؤلفون: Karen A. Autio, Daniel C. Danila, Susan F. Slovin, Howard I. Scher, Michael J. Morris, Nikolaus Schultz, Michael F. Berger, Sumit Middha, Charles L. Sawyers, Anuradha Gopalan, Wassim Abida, Melanie Hullings, Emily Carbone, David B. Solit, Victor E. Reuter, Joshua Armenia, Dana E. Rathkopf, Michael L. Cheng, Philip W. Kantoff, Jaclyn F. Hechtman
المصدر: Journal of Clinical Oncology. 36:5020-5020
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, business.industry, Fda approval, Microsatellite instability, Pembrolizumab, medicine.disease, Immune checkpoint, Blockade, 03 medical and health sciences, Prostate cancer, 030104 developmental biology, 0302 clinical medicine, Oncology, 030220 oncology & carcinogenesis, Cancer research, Medicine, DNA mismatch repair, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::da97a380e689add4a66783d1d7b23744Test
https://doi.org/10.1200/jco.2018.36.15_suppl.5020Test -
8
المؤلفون: Karen A. Autio, Gregory Shelkey, Melanie Hullings, Mia DeNunzio, Dana E. Rathkopf, Anthony Delacruz, Howard I. Scher, Katherine Pisano, Susan F. Slovin, Michael J. Morris
المصدر: Journal of Clinical Oncology. 34:e16529-e16529
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, business.industry, Phases of clinical research, Castration resistant, Discovery and development of mTOR inhibitors, medicine.disease, 03 medical and health sciences, Prostate cancer, 030104 developmental biology, 0302 clinical medicine, Oncology, 030220 oncology & carcinogenesis, medicine, Cancer research, In patient, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::82589ea82538374c15ba347888bc2839Test
https://doi.org/10.1200/jco.2016.34.15_suppl.e16529Test -
9
المؤلفون: Michael B. Petersen, Geert Mortier, Ian D. Krantz, Patrick M. Lombardi, Frank J. Kaiser, Claude Prigent, Elfride De Baere, Kathryn E. Cole, Tohru Kiyono, Sarah Ernst, Dinah Clark, Katsuhiko Shirahige, Laura Magnaghi-Jaulin, Nataliya Di Donato, Melanie Hullings, Erwan Watrin, Yutaka Suzuki, Naohito Nozaki, Jonathan J. Wilde, Lauren J. Francey, Patrick Willems, David W. Christianson, Takehiko Itoh, Ryuichiro Nakato, Yuki Katou, Christian Jaulin, Laird G. Jackson, Makiko Komata, Gabriele Gillessen-Kaesbach, Matthew A. Deardorff, Maninder Kaur, Masashi Minamino, Hiroyuki Seimiya, Yolanda Gyftodimou, Christophe Decroos, Victoria Mok Siu, Yuuichi Ishikawa, Kyotaro Hirashima, Katsuya Saitoh, Masashige Bando, Kentaro Takagaki, Toru Hirota
المساهمون: Division of Human Genetics and Molecular Biology, Children’s Hospital of Philadelphia (CHOP ), Department of Pediatrics, University of Pennsylvania-Perelman School of Medicine, University of Pennsylvania, Research Center for Epigenetic Disease, The University of Tokyo (UTokyo), Institut de Génétique et Développement de Rennes (IGDR), Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), School of Bioscience and Biotechnology, Tokyo Institute of Technology [Tokyo] (TITECH), Department of Chemistry, Center for Medical Genetics [Ghent], Ghent University Hospital, Institut für Klinische Genetik, Technische Universität Dresden = Dresden University of Technology (TU Dresden), Department of Genetics, Institute of Child Health, Division of Molecular Biotherapy, Japanese Foundation for Cancer Research, Department of Pathology, Division of Virology, National Cancer Center Research Institute, Department of Medical Genetics, Antwerp University Hospital [Edegem] (UZA), Bio-Frontier Research Center, Department of Clinical Genetics, Aarhus University Hospital, University of Western Ontario (UWO), Graduate School of Frontier Sciences, Department of Experimental Pathology, GENetic DIAgnostic Network (GENDIA), GENDIA Central Lab, Leicester Royal Infirmary, University Hospitals Leicester-University Hospitals Leicester, Institut für Humangenetik Lübeck, Universität zu Lübeck = University of Lübeck [Lübeck], Department of Obstetrics and Gynecology, Drexel University College of Medicine, Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), De Villemeur, Hervé, University of Pennsylvania [Philadelphia]-Perelman School of Medicine, University of Pennsylvania [Philadelphia], Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )-Centre National de la Recherche Scientifique (CNRS)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), Universität zu Lübeck [Lübeck]
المصدر: Deardorff, M A, Bando, M, Nakato, R, Watrin, E, Itoh, T, Minamino, M, Saitoh, K, Komata, M, Katou, Y, Clark, D, Cole, K E, De Baere, E, Decroos, C, Di Donato, N, Ernst, S, Francey, L J, Gyftodimou, Y, Hirashima, K, Hullings, M, Ishikawa, Y, Jaulin, C, Kaur, M, Kiyono, T, Lombardi, P M, Magnaghi-Jaulin, L, Mortier, G R, Nozaki, N, Petersen, M B, Seimiya, H, Siu, V M, Suzuki, Y, Takagaki, K, Wilde, J J, Willems, P J, Prigent, C, Gillessen-Kaesbach, G, Christianson, D W, Kaiser, F J, Jackson, L G, Hirota, T, Krantz, I D & Shirahige, K 2012, ' HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle ', English Nature, vol. 489, no. 7415, pp. 313-7 . https://doi.org/10.1038/nature11316Test
Nature
Nature, 2012, 489 (7415), pp.313-7. ⟨10.1038/nature11316⟩
Nature, Nature Publishing Group, 2012, 489 (7415), pp.313-7. ⟨10.1038/nature11316⟩مصطلحات موضوعية: Male, Models, Molecular, Transcription, Genetic, Chromosomal Proteins, Non-Histone, Protein Conformation, Cell Cycle Proteins, [SDV.GEN] Life Sciences [q-bio]/Genetics, Crystallography, X-Ray, Prophase, MESH: Mutant Proteins, 0302 clinical medicine, MESH: Protein Conformation, De Lange Syndrome, MESH: Proteins, [SDV.BDD]Life Sciences [q-bio]/Development Biology, Anaphase, Genetics, MESH: Chromatin Immunoprecipitation, 0303 health sciences, Multidisciplinary, MESH: Chondroitin Sulfate Proteoglycans, Nuclear Proteins, Acetylation, Chromatin, Establishment of sister chromatid cohesion, DNA-Binding Proteins, MESH: Prophase, MESH: Repressor Proteins, Female, biological phenomena, cell phenomena, and immunity, Engineering sciences. Technology, MESH: Acetylation, MESH: De Lange Syndrome, MESH: Models, Molecular, Chromatin Immunoprecipitation, Cornelia de Lange Syndrome, MESH: Mutation, Cohesin complex, Biology, MESH: Anaphase, MESH: Phosphoproteins, Article, Histone Deacetylases, MESH: Chromatin, 03 medical and health sciences, MESH: Cell Cycle Proteins, MESH: Chromosomal Proteins, Non-Histone, [SDV.BDD] Life Sciences [q-bio]/Development Biology, medicine, Humans, 030304 developmental biology, MESH: Adaptor Proteins, Signal Transducing, Adaptor Proteins, Signal Transducing, [SDV.GEN]Life Sciences [q-bio]/Genetics, MESH: Humans, Binding Sites, Cohesin, MESH: Transcription, Genetic, Proteins, NIPBL, Fibroblasts, medicine.disease, MESH: Crystallography, X-Ray, Phosphoproteins, MESH: Male, MESH: Histone Deacetylases, Repressor Proteins, MESH: Binding Sites, Chondroitin Sulfate Proteoglycans, MESH: Fibroblasts, MESH: HeLa Cells, Mutation, Mutant Proteins, MESH: Female, MESH: Nuclear Proteins, 030217 neurology & neurosurgery, HeLa Cells
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c946a259948fc2cc3a2a351405b3f06Test
https://pure.au.dk/portal/da/publications/hdac8-mutations-in-cornelia-de-lange-syndrome-affect-the-cohesin-acetylation-cycleTest(056fd46a-efdc-457d-b308-a51a56fd56b2).html