نتائج البحث - "Lactate dehydrogenase"

المساهمون: Institut Català de la Salut, [Ariceta G] Servei de Nefrologia Pediàtrica, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. [Barrios K, Brown BD, Rosskamp R] Dicerna Pharmaceuticals, Inc., Lexington, Massachusetts, USA. [Hoppe B] Dicerna Pharmaceuticals, Inc., Lexington, Massachusetts, USA. German Hyperoxaluria Center Cologne/Bonn, Bonn, Germany. [Langman CB] Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA. Ann and Robert H. Lurie Children’s Hospital of Chicago, Chicago, Illinois, USA, Vall d'Hebron Barcelona Hospital Campus

المصدر: Kidney International Reports
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Kidney International Reports, Vol 6, Iss 4, Pp 1088-1098 (2021)
Scientia

مصطلحات موضوعية: Small interfering RNA, Other subheadings::Other subheadings::/antagonists & inhibitors [Other subheadings], Lactate dehydrogenase A, Urinary system, 030232 urology & nephrology, lactate dehydrogenase A, Nutritional and Metabolic Diseases::Metabolic Diseases::Metabolism, Inborn Errors::Carbohydrate Metabolism, Inborn Errors::Hyperoxaluria, Primary [DISEASES], 030204 cardiovascular system & hematology, Pharmacology, lcsh:RC870-923, nedosiran, Excretion, Primary hyperoxaluria, 03 medical and health sciences, 0302 clinical medicine, RNA interference, Clinical Research, Enzymes and Coenzymes::Enzymes::Oxidoreductases::Alcohol Oxidoreductases::Lactate Dehydrogenases [CHEMICALS AND DRUGS], medicine, Otros calificadores::Otros calificadores::/antagonistas & inhibidores [Otros calificadores], education, education.field_of_study, Metabolisme, Errors congènits de, biology, business.industry, enzimas y coenzimas::enzimas::oxidorreductasas::alcohol oxidorreductasas::lactato deshidrogenasas [COMPUESTOS QUÍMICOS Y DROGAS], Epigenètica, medicine.disease, lcsh:Diseases of the genitourinary system. Urology, small interfering RNA, fenómenos genéticos::regulación de la expresión génica::epigénesis genética::silenciamiento génico::interferencia por ARN [FENÓMENOS Y PROCESOS], Inhibidors enzimàtics, Nephrology, enfermedades nutricionales y metabólicas::enfermedades metabólicas::alteraciones congénitas del metabolismo::trastornos congénitos del metabolismo de los carbohidratos::hiperoxaluria primaria [ENFERMEDADES], Renal physiology, biology.protein, Genetic Phenomena::Gene Expression Regulation::Epigenesis, Genetic::Gene Silencing::RNA Interference [PHENOMENA AND PROCESSES], Creatine kinase, business, primary hyperoxaluria, Nedosiran

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b6de5a9935a8f3c3b0e0a068586382Test
http://europepmc.org/articles/PMC8071644Test

6

Refill liquids for electronic cigarettes display peculiar toxicity on human endothelial cells

المؤلفون: Sara De Martin, Daniela Gabbia, Franco Biasioli, Sara Bogialli, Daniela Rainer, Ronald Gstir, Luca Cappellin, Andrea Boschetti

المصدر: Toxicology Reports
Toxicology Reports, Vol 8, Iss, Pp 456-462 (2021)

مصطلحات موضوعية: Health, Toxicology and Mutagenesis, Cytotoxicity, 010501 environmental sciences, Pharmacology, Lung injury, Toxicology, 01 natural sciences, Nicotine, 03 medical and health sciences, 0302 clinical medicine, RA1190-1270, Refill liquids, medicine, EVALI, e-vaping acute lung injury, HUVEC, human umbilical vein endothelial cells, Settore VET/07 - FARMACOLOGIA E TOSSICOLOGIA VETERINARIA, 0105 earth and related environmental sciences, ComputingMethodologies_COMPUTERGRAPHICS, e-Cig, electronic cigarette, LDH - Lactate dehydrogenase, LDH, lactate dehydrogenase, Chemistry, EVALI, Regular Article, ENDS, electronic nicotine delivery systems, Ldh release, Electronic cigarettes, Toxicity, Toxicology. Poisons, 030217 neurology & neurosurgery, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbddc929f4c1ea0d46cf52ba9a1190eaTest
http://europepmc.org/articles/PMC7933715Test

7

Artemisinin and artemisinin derivatives as anti-fibrotic therapeutics

المؤلفون: Tanja Dominko, Pamela J. Weathers, David Dolivo

المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 322-339 (2021)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: BUN, blood urea nitrogen, Artesunate, Review, Pharmacology, Col I, type I collagen, LAP, latency-associated peptide, chemistry.chemical_compound, 0302 clinical medicine, Scar, HUVEC, human umbilical vein endothelial cell, Fibrosis, CCl4, carbon tetrachloride, NAG, N-acetyl-β-d-glucosaminidase, General Pharmacology, Toxicology and Pharmaceutics, Artemisinin, HA, hyaluronic acid, 0303 health sciences, LDH, lactate dehydrogenase, LDH - Lactate dehydrogenase, mTOR, mechanistic target of rapamycin, TGF, β-transforming growth factor-β, DLA, dried leaf Artemisia, i.p., intraperitoneal, HSC, hepatic stellate cell, ALP - Alkaline phosphatase, DHA, dihydroartemisinin, ECM, extracellular matrix, MMP, matrix metalloproteinase, Alt alanine aminotransferase, 030220 oncology & carcinogenesis, MI, myocardial infarction, Fibroblast, TIMP, tissue inhibitor of metalloproteinase, medicine.drug, TGF-β, Anti fibrotic, ASP, aspartate aminotransferase, PCNA, proliferating cell nuclear antigen, BDL, bile duct ligation, FLS, fibroblast-like synoviocyte, STZ, streptozotocin, PHN, passive heymann nephritis, CTGF, connective tissue growth factor, 03 medical and health sciences, ROS, reactive oxygen species, ALT, alanine aminotransferase, parasitic diseases, medicine, BAD, BCL-2-associated agonist of cell death, sCr, serum creatinine, NICD, Notch intracellular domain, UUO, unilateral ureteral obstruction, 030304 developmental biology, Myofibroblast, ALP, alkaline phosphatase, business.industry, lcsh:RM1-950, medicine.disease, AMPK, AMP-activated protein kinase, lcsh:Therapeutics. Pharmacology, Artemisia, chemistry, Tissue fibrosis, BSA, bovine serum albumin, α-SMA, smooth muscle α-actin, business, EMT, epithelial-to-mesenchymal transition, MAPK, mitogen-activated protein kinase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b31e277e49b3a3364e9726d531259ad4Test
https://doi.org/10.1016/j.apsb.2020.09.001Test

8

Neomenthol prevents the proliferation of skin cancer cells by restraining tubulin polymerization and hyaluronidase activity

المؤلفون: Kaneez Fatima, Abha Meena, Suaib Luqman, Nusrat Masood, Zahoor Ahmad Wani

المصدر: Journal of Advanced Research

مصطلحات موضوعية: TRIG, Triglyceraldehyde, Skin Neoplasms, Cell, DOXO, Doxorubicin, Hyaluronidase, Pharmacology, NaOH, Sodium hydroxide, Polymerization, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, Mice, 0302 clinical medicine, BIL, Bilirubin total & direct, Neomenthol, PEP A, pepstatin A, Cancer biomarker, MEF, Mean erythrocyte fragility, HYAL, Hyaluronidase, PBS, Phosphate buffer saline, CM-H2DCFDA, Chloromethyl derivative of dichloro fluorescin diacetate, HA, Hyaluronic acid, Epidermoid carcinoma, Human epidermoid carcinoma, 030220 oncology & carcinogenesis, RBC, Red blood cell, DMEM, Dulbecco’s minimal essential media, SRB, Sulphorhodamine B, BUN, Blood urea nitrogen, FACS, Fluorescence-Activated Cell Sorting, AKLP, Alkaline phosphatase, Hyaluronoglucosaminidase, NADPH, Nicotinamide adenine dinucleotide phosphate hydrogen, TMPD, N,N,N′,N′-tetramethyl-p-phenylenediamine, Article, 03 medical and health sciences, In vivo, Ehrlich Ascites Carcinoma, BE, Binding energy, Humans, CATD, Cathepsin D, LDH, Lactate dehydrogenase, COX-2, Cyclooxygenase 2, FOX, Ferrous oxidation-xylenol orange, DMSO, Dimethyl sulfoxide, mTOR, Mammalian target of rapamycin, In vitro, Ab/Am, Antibiotic/antimycotic, NRU, Neutral red uptake, EC50, Half maximal effective concentration, 030104 developmental biology, IC50, Half maximal inhibitory concentration, EAC, Ehlrich Ascites Carcinoma, RPMI, Roswell park memorial institute, ROS, Reactive oxygen species, 0301 basic medicine, HDL, High density lipoprotein, TNBS, Trinitrobenzenesulphonic acid, PI3K, Phosphotidyl inositol-3 kinase, URIC, Uric acid, DNA, Deoxyribonucleic acid, GAPDH, Glyceraldehyde 3-phosphate dehydrogenase, HEPES, N-2-hydroxyethylpiperazine-N′-2-ethanesulfonic acid, Tubulin, OECD, Organization for Economic Co-operation and Development, SGPT, Alanine aminotransferase, LOX-5, Lipoxygenase-5, DFMO, α-difluoro methyl ornithine, Multidisciplinary, WBC, White blood cell, Chemistry, ELISA, enzyme-linked immunosorbent assay, PKB/Akt, Protein kinase B, AA, Arachidonic acid, RNase A, Ribonuclease A, TPR, Total protein, Molecular Docking Simulation, medicine.anatomical_structure, TCA, Tricarboxylic acid, CHOL, Cholesterol, Ki, Inhibitory constant, medicine.drug, ODC, Ornithine decarboxylase, DHFR, Dihydrofolatereductase, BSA, Bovine serum albumin, PDB, Protein Data Bank, medicine, Animals, MMP, Mitochondrial membrane potential, DCFDA, 2′,7′ dichloro fluorescin diacetate, RNA, Ribonucleic acid, RIPA, Radio immune precipitation assay buffer, EDTA, Ethylene diamine tetra acetic acid, IC50, TPA, 12-O-Tetradecanoylphorbol-13-acetate, ComputingMethodologies_COMPUTERGRAPHICS, TRPM8, Transient receptor potential member 8, Cell Proliferation, HDAC, Histone deacetylase, MTX, Methotrexate, OF, Osmotic fragility, PI, Propidium iodide, FDA, Food and Drug Administration, HEK293 Cells, PDT, Podophyllotoxin, Cell culture, NAC, N-acetyl cysteine, SGOT, Aspartate aminotransferase, CRTN, Creatinine, FBS, Fetal bovine serum, PCR, Polymerase chain reaction, Rh123, Rhodamine 123, Ex vivo, IDT, Integrated DNA Technologies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7618e7dc6e2d535e1930d5f8c2bf7d7eTest
https://doi.org/10.1016/j.jare.2021.06.003Test

9

Effects of hydroxyurea on cytotoxicity, inflammation and oxidative stress markers in neutrophils of patients with sickle cell anemia: dose-effect relationship

المؤلفون: Romélia Pinheiro Gonçalves Lemes, Luzia Kalyne Almeida Moreira Leal, Alano Martins Pedrosa

المصدر: Hematology, Transfusion and Cell Therapy, Vol 43, Iss 4, Pp 468-475 (2021)
Hematology, Transfusion and Cell Therapy
Hematology, Transfusion and Cell Therapy, Volume: 43, Issue: 4, Pages: 468-475, Published: 29 NOV 2021

وصف الملف: text/html

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5eadebd89ea53b6a6a4167044df85e3Test
http://www.sciencedirect.com/science/article/pii/S2531137920302820Test

10

Cinnamomum zeylanicum Blume (Ceylon cinnamon) bark extract attenuates doxorubicin induced cardiotoxicity in Wistar rats

المؤلفون: Lakmini Mudduwa, Kamani Ayoma Perera Wijewardana Jayatilaka, Jayasinghe Arachchige Nirosha Sandamali, Ruwani Punyakanthi Hewawasam

المصدر: Saudi Pharmaceutical Journal, Vol 29, Iss 8, Pp 820-832 (2021)
Saudi Pharmaceutical Journal : SPJ

مصطلحات موضوعية: 0301 basic medicine, Glutathione reductase, Pharmaceutical Science, Pharmacology, medicine.disease_cause, SOD, Superoxide dismutase, Lipid peroxidation, DNA, Deoxyribonucleic acid, chemistry.chemical_compound, 0302 clinical medicine, ABTS, 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid), GR, Glutathione reductase, USA, United States of America, DPPH, 2,2-diphenyl-1-picrylhydrazyl, chemistry.chemical_classification, Cinnamomum zeylanicum Bark Extract, cTnI, Cardiac troponin I, Myeloperoxidase, biology, NT-pro BNP, N terminal- pro brain natriuretic peptide, Glutathione peroxidase, Antioxidant effect, Cinnamomum zeylanicum, FRAP, Ferric reducing antioxidant power, IP, Intraperitoneal, ELISA, Enzyme-linked immunosorbent assay, 030220 oncology & carcinogenesis, GPx, Glutathione peroxidase, Original Article, H & E, Haematoxylin and eosin, AST, Aspartate aminotransferase, MPO, Myeloperoxidase, PBS, Phosphate buffered saline, RM1-950, NADPH, Nicotinamide adenine dinucleotide phosphate hydrogen, NO, Nitric oxide, WHO, World Health Organization, Cinnamomum zeylanicum bark extract, GSH, Reduced glutathione, 03 medical and health sciences, medicine, MDA, Malondialdehyde, LDH, Lactate dehydrogenase, ABEC, Aqueous bark extract of Cinnamomum zeylanicum, Glutathione, biology.organism_classification, Cardiotoxicity, Oxidative-stress, 030104 developmental biology, chemistry, Doxorubicin, Therapeutics. Pharmacology, Oxidative stress, ROS, Reactive oxygen species, Cinnamomum

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ec834331604e75cffd6b67e9822c83Test
http://www.sciencedirect.com/science/article/pii/S1319016421001183Test

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