نتائج البحث

1

Sleep dysregulation in binge eating disorder and 'food addiction': the orexin (hypocretin) system as a potential neurobiological link

المؤلفون: Deborah Mitchison, Jacqueline B. Mehr, Hannah E. Bowrey, Morgan H. James

المصدر: Neuropsychopharmacology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b85510d72a11b3721467aec00f30615Test
https://doi.org/10.1038/s41386-021-01052-zTest

2

Preclinical and clinical efficacy of orexin receptor antagonist Lemborexant (Dayvigo®) on insomnia patients

المؤلفون: Kenzo Muramoto, Noriyuki Koyama, Michinori Koebisu, Maika Nishida

المصدر: Folia Pharmacologica Japonica. 156:114-119

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, business.industry, Lemborexant, Antagonist, Orexin receptor, Orexin, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, mental disorders, medicine, Insomnia, medicine.symptom, Receptor, business, Adverse effect, 030217 neurology & neurosurgery, Somnolence

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::f08b5f41d71b13caee8533023c580547Test
https://doi.org/10.1254/fpj.20093Test

3

Wakefulness-Promoting Effects of Lateral Hypothalamic Area–Deep Brain Stimulation in Traumatic Brain Injury-Induced Comatose Rats: Upregulation of α1-Adrenoceptor Subtypes and Downregulation of Gamma-Aminobutyric Acid β Receptor Expression Via the Orexins Pathway

المؤلفون: Yunliang Tang, Linyang Zhong, Jun Wang, Haiping Liu, Guohui Lu, Jing Xiong, Zhen Feng, Wen Ye, Xiaoyang Dong

المصدر: World Neurosurgery. 152:e321-e331

مصطلحات موضوعية: Male, medicine.medical_specialty, Deep brain stimulation, Consciousness, Lateral hypothalamus, Traumatic brain injury, Deep Brain Stimulation, medicine.medical_treatment, Stimulation, Functional Laterality, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Receptors, GABA, Orexin Receptors, Receptors, Adrenergic, alpha-1, Internal medicine, Brain Injuries, Traumatic, Animals, Urea, Medicine, Anesthesia, Coma, Naphthyridines, Wakefulness, Prefrontal cortex, Injections, Intraventricular, Benzoxazoles, Orexins, business.industry, Antagonist, Electroencephalography, medicine.disease, Rats, nervous system diseases, Endocrinology, Delta Rhythm, nervous system, Hypothalamic Area, Lateral, 030220 oncology & carcinogenesis, Female, Surgery, Neurology (clinical), medicine.symptom, business, 030217 neurology & neurosurgery, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83432079bf2bec81c804a5eab5ba0266Test
https://doi.org/10.1016/j.wneu.2021.05.089Test

4

Pharmacological Interactions between the Dual Orexin Receptor Antagonist Daridorexant and Ethanol in a Double-Blind, Randomized, Placebo-Controlled, Double-Dummy, Four-Way Crossover Phase I Study in Healthy Subjects

المؤلفون: Rob Zuiker, Benjamin Berger, Sander Brooks, Muriel Richard, Clemens Muehlan, Jasper Dingemanse

المصدر: CNS Drugs. 34:1253-1266

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe98b4ca3557e59bdac0932aecd3a3e0Test
https://doi.org/10.1007/s40263-020-00768-8Test

5

CD200–CD200R immune checkpoint engagement regulates ILC2 effector function and ameliorates lung inflammation in asthma

المؤلفون: Benjamin P. Hurrell, Meng Li, Jacob D. Painter, Pedram Shafiei-Jahani, Yong-Hwee Eddie Loh, Doumet Georges Helou, Omid Akbari, Emily Howard, Lauriane Galle-Treger, Christine Quach

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, Science, General Physics and Astronomy, Inflammation, Innate lymphoid cells, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Antigens, CD, Orexin Receptors, Eosinophilia, medicine, Animals, Humans, Lymphocytes, Receptor, Lung, Cell Proliferation, Mice, Inbred BALB C, Multidisciplinary, Membrane Glycoproteins, Effector, business.industry, Interleukins, Innate lymphoid cell, General Chemistry, Pneumonia, respiratory system, Interleukin-33, Immune checkpoint, Asthma, Immunity, Innate, respiratory tract diseases, DNA-Binding Proteins, Disease Models, Animal, 030104 developmental biology, Cytokine, 030220 oncology & carcinogenesis, Humanized mouse, Immunology, Cytokines, Female, Signal transduction, medicine.symptom, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::312552aaf8bb384498450cb85b718470Test
https://doaj.org/article/fea260e6f82a47a287a0d596f7eecfe6Test

6

CD200 Limits Monopoiesis and Monocyte Recruitment in Atherosclerosis

المؤلفون: Christina Kassiteridi, Aditi Upadhye, Patricia Green, Esther Lutgens, Anusha N. Seneviratne, Annelie Shami, Tanyaporn Pattarabanjird, Inhye Park, Angela M. Taylor, Keith M. Channon, Ashok Handa, Coleen A. McNamara, Jennifer Cole, Richard O. Williams, Mika Falck-Hansen, Thibault Griseri, Claudia Monaco, Michael E. Goddard

المساهمون: Medical Biochemistry, ACS - Atherosclerosis & ischemic syndromes, AII - Inflammatory diseases

المصدر: Circulation Research
Circulation research, 129(2), 280-295. Lippincott Williams and Wilkins

مصطلحات موضوعية: 0301 basic medicine, Male, CCR2, Physiology, Mice, Knockout, ApoE, Coronary Artery Disease, 030204 cardiovascular system & hematology, Monocytes, 0302 clinical medicine, Orexin Receptors, Macrophage, Phosphorylation, Aorta, Cells, Cultured, Original Research, Aged, 80 and over, Membrane Glycoproteins, Middle Aged, Plaque, Atherosclerotic, Chemotaxis, Leukocyte, medicine.anatomical_structure, STAT1 Transcription Factor, monocyte, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, Female, medicine.symptom, Cardiology and Cardiovascular Medicine, Signal Transduction, Neointima, Adult, bone marrow, Aortic Diseases, Inflammation, macrophage, 03 medical and health sciences, Monocytosis, Antigens, CD, medicine, Animals, Humans, Aged, business.industry, Monocyte, Macrophages, medicine.disease, Immune checkpoint, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, inflammation, Cancer research, Leukopoiesis, Bone marrow, atherosclerosis, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a1903367f800ce9881cdffb218d4569Test
http://europepmc.org/articles/PMC8260471Test

7

Population Pharmacokinetics and Exposure‐Response Analyses for the Most Frequent Adverse Events Following Treatment With Lemborexant, an Orexin Receptor Antagonist, in Subjects With Insomnia Disorder

المؤلفون: Jagadeesh Aluri, Margaret Moline, Ziad Hussein, Oneeb Majid, Bojan Lalovic, Ishani Landry

المصدر: Journal of Clinical Pharmacology

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Adolescent, exposure‐response analysis, Pyridines, insomnia, Lemborexant, Administration, Oral, Drug Elimination Routes, Placebo, 030226 pharmacology & pharmacy, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Pharmacometrics, Pharmacokinetics, population pharmacokinetics, Sleep Initiation and Maintenance Disorders, Internal medicine, medicine, Humans, Pharmacology (medical), Adverse effect, Aged, Aged, 80 and over, Pharmacology, Clinical Trials as Topic, business.industry, Middle Aged, medicine.disease, Orexin receptor, Pyrimidines, Upper respiratory tract infection, orexin antagonist, Area Under Curve, 030220 oncology & carcinogenesis, Female, Orexin Receptor Antagonists, medicine.symptom, business, Body mass index, Somnolence

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b19a5d8098fca84dc00ffa96a77f0381Test
https://doi.org/10.1002/jcph.1683Test

8

The association of circulating endocannabinoids with appetite regulatory substances in obese women

المؤلفون: Fereshteh Aliasgari, Mohammad Alizadeh, Reza Mahdavi, Soghra Aliasgharzadeh, Neda Lotfi Yagin

المصدر: Obesity Research & Clinical Practice. 14:321-325

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::531ce89b166d60635223c795f514f4c6Test
https://doi.org/10.1016/j.orcp.2020.05.007Test

9

Involvement of Orexinergic System Within the Nucleus Accumbens in Pain Modulatory Role of the Lateral Hypothalamus in Orofacial Pain Model

المؤلفون: Amir Haghparast, Laleh Rezaee, Abbas Haghparast, Azita Tehranchi, Tina Matini, Mohammad Rahban

المصدر: Neurochemical Research. 45:851-859

مصطلحات موضوعية: Male, Nociception, 0301 basic medicine, medicine.medical_specialty, Orofacial pain, Carbachol, Lateral hypothalamus, Pyridines, Stimulation, Nucleus accumbens, Biochemistry, Nucleus Accumbens, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Facial Pain, Orexin Receptors, Formaldehyde, Internal medicine, medicine, Animals, Urea, Naphthyridines, Rats, Wistar, Benzoxazoles, business.industry, General Medicine, Analgesics, Non-Narcotic, Isoquinolines, TCS-OX2-29, Orexin, 030104 developmental biology, Endocrinology, Hypothalamic Area, Lateral, Orexin Receptor Antagonists, medicine.symptom, business, 030217 neurology & neurosurgery, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e54948666d7b3114d5ad44f4acfd00ecTest
https://doi.org/10.1007/s11064-020-02957-9Test

10

Orexin A in adolescents with anxiety disorders

المؤلفون: Ömer Faruk Akça, Necati Uzun, İbrahim Kılınç

المصدر: International Journal of Psychiatry in Clinical Practice. 24:127-134

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f33041eec0abc0d3408683314769f58Test
https://doi.org/10.1080/13651501.2019.1711425Test

تنقيح النتائج