نتائج البحث - "Muscarinic"

المساهمون: HUS Medical Imaging Center, Kliinisen neurofysiologian yksikkö, Department of Neurosciences, University of Helsinki, Clinicum, Neurologian yksikkö, HUS Neurocenter, Helsinki University Hospital Area

المصدر: Sleep Medicine. 77:82-87

مصطلحات موضوعية: Narcolepsy type 1, Cataplexy, Hypocretin, 3124 Neurology and psychiatry, Receptors, G-Protein-Coupled, M2 muscarinic receptor autoantibodies, AUTONOMIC CONTROL, 03 medical and health sciences, 0302 clinical medicine, SCHIZOPHRENIA, Muscarinic acetylcholine receptor, medicine, Humans, Receptor, MUSCARINIC RECEPTORS, Autoantibodies, Narcolepsy, Orexins, CARDIOMYOPATHY, HEART-RATE-VARIABILITY, STRIATUM, business.industry, Neuropeptides, Intracellular Signaling Peptides and Proteins, Autoantibody, Muscarinic acetylcholine receptor M2, General Medicine, medicine.disease, SLEEP, 3. Good health, Orexin, Nociception, 030228 respiratory system, Nociception receptor autoantibodies, Immunology, Female, medicine.symptom, CATAPLEXY, business, 030217 neurology & neurosurgery, beta 2 adrenergic receptor autoantibodies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2726a7dbdfbacf8ff3a0ab6e206b423bTest
https://doi.org/10.1016/j.sleep.2020.11.038Test

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Targeting autophagy using small-molecule compounds to improve potential therapy of Parkinson's disease

المؤلفون: Lu Feng, Kai Zhang, Bo Liu, Tingting Jiang, Liang Ouyang, Guan Wang, Jiamei Li, Shiou Zhu, Junping Pei

المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 3015-3034 (2021)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: Target, ONRs, orphan nuclear receptors, Parkinson's disease, Small-molecule compound, MPP+, 1-methyl-4-phenylpyridinium, Autolysosome, GAPDH, glyceraldehyde 3-phosphate dehydrogenase, GBA, glucocerebrosidase β acid, Review, MPTP, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine, Disease, mTORC1, mTOR, the mammalian target of rapamycin, PD, Parkinson's disease, 0302 clinical medicine, CL, clearance rate, DAT, dopamine transporter, HDAC6, histone deacetylase 6, PD therapy, A2A, adenosine 2A, MYCBP2, MYC-binding protein 2, TFEB, transcription factor EB, AUTAC, autophagy targeting chimera, General Pharmacology, Toxicology and Pharmaceutics, SAS, solvent accessible surface, 0303 health sciences, α-syn, α-synuclein, ALP, autophagy-lysosomal pathway, AADC, aromatic amino acid decarboxylase, DJ-1, Parkinson protein 7, PI3K, phosphatidylinositol 3-kinase, COMT, catechol-O-methyltransferase, LUHMES, lund human mesencephalic, LRRK2, CMA, chaperone-mediated autophagy, KI, knockin, 030220 oncology & carcinogenesis, LRS, leucyl-tRNA synthetase, BBB, blood−brain barrier, SN, substantia nigra, IMPase, inositol monophosphatase, IPPase, inositol polyphosphate 1-phosphatase, HSPA8, heat shock 70 kDa protein 8, MAO-B, monoamine oxidase B, PREP, prolyl oligopeptidase, Parkinson's disease (PD), DR, dopamine receptor, PDE4, phosphodiesterase 4, AMPK, 5ʹAMP-activated protein kinase, 5-HT2C, serotonin 2C, SNCA, α-synuclein gene, TSC2, tuberous sclerosis complex 2, RM1-950, LIMP-2, lysosomal integrated membrane protein-2, CNS, central nervous system, 5-HT2A, Serotonin 2A, ER, endoplasmic reticulum, ATG, autophagy related protein, 03 medical and health sciences, PLC, phospholipase C, ROS, reactive oxygen species, ERRα, estrogen-related receptor alpha, SAR, structure–activity relationship, ULK1, UNC-51-like kinase 1, medicine, Autophagy, NMDA, N-methyl-d-aspartic acid, mAChR, muscarinic acetylcholine receptor, GWAS, genome-wide association study, LAMP2A, lysosome-associated membrane protein 2 A, Lamp2a, type 2A lysosomal-associated membrane protein, 030304 developmental biology, Parkin, parkin RBR E3 ubiquitin−protein ligase, PINK1, PTEN-induced kinase 1, ATTEC, autophagosome-tethering compound, ATP13A2, ATPase cation transporting 13A2, business.industry, ULK1, medicine.disease, LC3, light chain 3, PI3P, phosphatidylinositol 3-phosphate, SYT11, synaptotagmin 11, AUC, the area under the curve, UPS, ubiquitin−proteasome system, TFEB, DA, dopamine, Therapeutics. Pharmacology, business, BAF, bafilomycinA1, HSC70, heat shock cognate 71 kDa protein, Neuroscience, 3-MA, 3-methyladenine, F, oral bioavailability, LRRK2, leucine-rich repeat sequence kinase 2

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d12dab43aca56bfd6a912c2aa71297ffTest
http://www.sciencedirect.com/science/article/pii/S2211383521000642Test

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Healthcare Resource Utilization, Exacerbations, and Readmissions Among Medicare Patients with Chronic Obstructive Pulmonary Disease After Long-Acting Muscarinic Antagonist Therapy Initiation with Soft Mist versus Dry Powder Inhalers

المؤلفون: Jessica Franchino-Elder, Ami R Buikema, David Singer, Caitlin A Elliott, Lindsay G S Bengtson

المصدر: International Journal of Chronic Obstructive Pulmonary Disease

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Muscarinic Antagonists, International Journal of Chronic Obstructive Pulmonary Disease, Medicare, Patient Readmission, chronic obstructive pulmonary disease, soft mist inhaler, readmissions, 03 medical and health sciences, Pulmonary Disease, Chronic Obstructive, 0302 clinical medicine, dry powder inhaler, exacerbations, Internal medicine, Administration, Inhalation, medicine, COPD, long-acting muscarinic antagonist, Humans, 030212 general & internal medicine, Adrenergic beta-2 Receptor Agonists, Asthma, Original Research, healthcare resource utilization, Aged, SMI, business.industry, Inhaler, LAMA, Dry Powder Inhalers, General Medicine, Odds ratio, medicine.disease, Confidence interval, Dry-powder inhaler, United States, Discontinuation, Bronchodilator Agents, DPI, 030228 respiratory system, Cohort, Disease Progression, Female, business, Delivery of Health Care

وصف الملف: text/html

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5802e00c24becf505175d25f83402e14Test
http://europepmc.org/articles/PMC7732756Test

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When to Use Initial Triple Therapy in COPD: Adding a LAMA to ICS/LABA by Clinically Important Deterioration Assessment

المؤلفون: Wen-Chien Cheng, Wu-Huei Hsu, Chih-Yu Chen, Biing-Ru Wu, Wei Chun Chen, Chia-Hung Chen, Chih Yen Tu, Te Chun Hsia, Wei-Chih Liao

المصدر: International Journal of Chronic Obstructive Pulmonary Disease

مصطلحات موضوعية: long-acting β2 agonist, medicine.medical_specialty, Multivariate analysis, medicine.drug_class, LABA, Muscarinic Antagonists, Disease, International Journal of Chronic Obstructive Pulmonary Disease, inhaled corticosteroid, CID, Pulmonary Disease, Chronic Obstructive, 03 medical and health sciences, 0302 clinical medicine, Adrenal Cortex Hormones, Internal medicine, Administration, Inhalation, long-acting muscarinic antagonist, COPD, Humans, Medicine, 030212 general & internal medicine, chronic pulmonary obstructive disease, Adrenergic beta-2 Receptor Agonists, Original Research, clinically important deterioration, Retrospective Studies, biology, Receiver operating characteristic, business.industry, LAMA, Muscarinic antagonist, General Medicine, Lama, biology.organism_classification, medicine.disease, Bronchodilator Agents, 030228 respiratory system, ICS, triple therapy, Ics laba, Disease Progression, Corticosteroid, Drug Therapy, Combination, business, medicine.drug

وصف الملف: text/html

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40d1c3a1c43ae6a1bb67ff4d5df786a6Test
https://doi.org/10.2147/copd.s279482Test

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