المؤلفون: Hans-Peter Hammes, Elena Heidenreich, Peter P. Nawroth, Martina U. Muckenthaler, Sandro Altamura, Thomas Fleming, Andrea Schlotterer, Katja Müdder, Ruiyue Qiu

المصدر: Molecular Metabolism, Vol 51, Iss, Pp 101235-(2021)
Molecular Metabolism

مصطلحات موضوعية: 0301 basic medicine, Blood Glucose, Male, DR, diabetic retinopathy, Hepcidin, medicine.disease_cause, Mice, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, MetS, Metabolic Syndrome, Internal medicine, biology, Fpn, Ferroportin, Fatty liver, Liver, DIOS, dysmetabolic iron overload syndrome, CRP, C-reactive protein, Receptors, Leptin, HH, hereditary hemochromatosis, Original Article, IRP, Iron Regulatory Protein, medicine.medical_specialty, Iron Overload, Iron, 030209 endocrinology & metabolism, Mice, Transgenic, IR, Insulin Resistance, SEM, standard error of the mean, 03 medical and health sciences, Insulin resistance, ROS, reactive oxygen species, NASH, Non Alcoholic Steatohepatitis, NAFLD, medicine, Animals, Humans, Molecular Biology, business.industry, NTBI, Non Transferrin Bound Iron, Cell Biology, medicine.disease, RC31-1245, IRS1, Db/db Mouse, Disease Models, Animal, Oxidative Stress, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, biology.protein, NAFLD, Non Alcoholic Fatty Liver Disease, Lipid Peroxidation, Steatosis, Metabolic syndrome, business, Oxidative stress, IRE, Iron Responsive Element, T2DM, Type 2 Diabetes Mellitus

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::746ad7abfa625d87337f2502f8e59462Test
http://www.sciencedirect.com/science/article/pii/S2212877821000806Test

المؤلفون: Carrie E. McCurdy, Kenneth N. Maclean, Paul Kievit, Bryan C. Bergman, Rachel C. Janssen, Peter R. Baker, Christopher M. Mulligan, Tyler Dean, Diana L. Takahashi, Travis Nemkov, Kjersti Aagaard, Hua Jiang, Stephanie R. Wesolowski, Angelo D'Alessandro, Jacob E. Friedman

المصدر: Molecular Metabolism, Vol 18, Iss, Pp 25-41 (2018)
Molecular Metabolism

مصطلحات موضوعية: 0301 basic medicine, Steatosis, VIP, variable importance in projection, Hypoxemia, AUC, area under the curve, PC, phosphatidylcholine, 0302 clinical medicine, WSD, Western-style diet, Non-alcoholic Fatty Liver Disease, Pregnancy, Fetal programming, Hyperlipidemia, DAG, diacylglyceride, VLDL, very low-density lipoprotein, Hypoxia, 2. Zero hunger, TG, triglyceride, NEFA, non-esterified fatty acid, NHP, non-human primate, Fatty liver, 3. Good health, Liver, Lipotoxicity, CON, control, OB-WSD, Western-style diet induced obesity group, IV-GTT, intravenous glucose tolerance test, Prenatal Exposure Delayed Effects, Original Article, Female, Diet, Healthy, PLS-DA, partial least squares discriminant analysis, TCA, tricarboxylic acid cycle, NAFLD, non-alcoholic fatty liver disease, lcsh:Internal medicine, medicine.medical_specialty, Offspring, NASH, non-alcoholic steatohepatitis, Citric Acid Cycle, Metabolomic, 030209 endocrinology & metabolism, DNL, de novo lipogenesis, TBARs, thiobarbituric acid reactive substances, OB-DR, diet reversal group, 03 medical and health sciences, Fetus, Internal medicine, medicine, TBARS, Animals, Obesity, AA, amino acid, lcsh:RC31-1245, Molecular Biology, Triglycerides, business.industry, Gluconeogenesis, Maternal Nutritional Physiological Phenomena, Cell Biology, medicine.disease, Oxidative Stress, 030104 developmental biology, Endocrinology, Diet, Western, Macaca, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06dccd8288a52f01636dbe7fd72ba0fTest
https://doi.org/10.1016/j.molmet.2018.09.008Test

المؤلفون: Anika Nier, Ina Bergheim, Amélia Camarinha-Silva, Cheng Jun Jin, Annette Brandt, Anja Baumann, Angélica Hernández-Arriaga, Dragana Rajcic, Victor Sánchez, Finn Jung

المصدر: Redox Biology
Redox Biology, Vol 41, Iss, Pp 101879-(2021)

مصطلحات موضوعية: 0301 basic medicine, Medicine (General), F, fructose, Arginine, Clinical Biochemistry, AST, aspartate aminotransferase, Biochemistry, Mice, AUC, area under the curve, NOHA, N(ω)-hydroxy-nor-l-arginine, Liver disease, chemistry.chemical_compound, PCR, polymerase chain reaction, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, ARG2, arginase 2, 3-NT, 3-nitrotyrosine, Citrulline, Biology (General), NAS, NAFLD activity score, Fatty liver, FFC, fat-, fructose- and cholesterol-rich diet, L-Cit, l-citrulline, Arginase, medicine.anatomical_structure, Liver, iNOS, inducible nitric oxide synthase, Female, Research Paper, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, QH301-705.5, C, control diet, NASH, non-alcoholic steatohepatitis, TNFα, tumor necrosis factor alpha, Intestinal permeability, Diet, High-Fat, SEM, standard error of the mean, NO, 03 medical and health sciences, R5-920, Tlr4, toll-like receptor 4, 4-HNE, 4-hydroxynonenal, ALT, alanine aminotransferase, Internal medicine, medicine, Animals, Hepatic inflammation, Gpr41, G-protein-coupled receptor 41, NO, nitric oxide, business.industry, Bacterial endotoxin, Organic Chemistry, E%, percentage of energy, medicine.disease, ZO-1, zonula occludens 1, Small intestine, GTT, glucose-tolerance-test, Mice, Inbred C57BL, Toll-Like Receptor 4, 030104 developmental biology, Endocrinology, chemistry, Dietary Supplements, Myd88, myeloid differentiation primary response 88, Gpr43, G-protein-coupled receptor 43, Steatohepatitis, business, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c29ebb68a39a4a69ad56089e73e70eTest
https://doi.org/10.1016/j.redox.2021.101879Test

المؤلفون: Elisabeth D. Galsgaard, Henrik D. Pedersen, Berit Østergaard Christoffersen, Merete Fredholm, Markus Latta, Dorte Holst, Susanna Cirera

المصدر: Journal of Clinical and Experimental Hepatology
Pedersen, H D, Galsgaard, E D, Christoffersen, B, Cirera, S, Holst, D, Fredholm, M & Latta, M 2020, ' NASH-inducing Diets in Göttingen Minipigs ', Journal of Clinical and Experimental Hepatology, vol. 10, no. 3, pp. 211-221 . https://doi.org/10.1016/j.jceh.2019.09.004Test

مصطلحات موضوعية: medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, Porcine, ALT, alanine transaminase, NASH, non-alcoholic steatohepatitis, GLDH, glutamate dehydrogenase, Choline, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Fibrosis, AST, aspartate transaminase, Internal medicine, Fatty liver, FFC, high-fat, fructose, cholesterol, Medicine, Animal model, amino acid defined high-fat diet (-S, with sucrose, Sirius Red, Hepatology, EDTA, ethylenediaminetetraacetic acid, ALP, alkaline phosphatase, business.industry, Cholesterol, GGT, gamma-glutamyltransferase, HE, hematoxylin and eosin, Fructose, medicine.disease, Endocrinology, chemistry, CD45, cluster of differentiation 45, 030220 oncology & carcinogenesis, Hepatic stellate cell, 030211 gastroenterology & hepatology, Original Article, F, with fructose), SMA, smooth muscle actin, CDAHFD, choline-deficient, Steatosis, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05e1f5726ee082ed2c5c2d742ea87d1Test
https://pubmed.ncbi.nlm.nih.gov/32405177Test

المؤلفون: Ina Bergheim, Finn Jung, Anika Nier, Cheng Jun Jin, Annette Brandt, Anja Baumann, José C. Fernández-Checa, Vicent Ribas, Carmen García-Ruiz

المساهمون: Federal Ministry of Education and Research (Germany), Agencia Estatal de Investigación (España), Ministerio de Economía y Competitividad (España), Ministerio de Ciencia, Innovación y Universidades (España), Centro de Investigación Biomédica en Red Enfermedades Hepáticas y Digestivas (España), Instituto de Salud Carlos III, Fundación BBVA, University of Vienna

المصدر: Redox Biology
Redox Biology, Vol 21, Iss, Pp-(2019)
Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: 0301 basic medicine, Ir, insulin receptor, Tlr, toll-like receptor, Clinical Biochemistry, Ppia, peptidylprolyl isomerase A, DCE, decaffeinated coffee effect, DExDCE, interaction between diet and decaffeinated coffee, Biochemistry, Coffee, chemistry.chemical_compound, ZO-1, zonula occludens-1, Mice, 0302 clinical medicine, PCR, polymerase chain reaction, Coffees, Non-alcoholic Fatty Liver Disease, 3-NT, 3-nitrotyrosine, Intestinal Mucosa, DeCaf, decaffeinated coffee, lcsh:QH301-705.5, Barrier function, ANOVA, analysis of variance, lcsh:R5-920, NAS, NAFLD activity score, Atf, activating transcription factor 6, Fatty liver, Lbp, lipopolysaccharide binding protein, FFC, fat-, fructose- and cholesterol-rich diet, Endoplasmic Reticulum Stress, Immunohistochemistry, iNOS, medicine.anatomical_structure, Pdi, protein disulfide isomerase, Liver, GTT, glucose tolerance test, Female, medicine.symptom, lcsh:Medicine (General), Grp78, 78 kDa glucose-regulated protein, Research Paper, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, ALT, alanine transaminase, NASH, non-alcoholic steatohepatitis, Inflammation, Il, interleukin, Intestinal permeability, Nitric Oxide, Permeability, Nitric oxide, 03 medical and health sciences, Insulin resistance, Internal medicine, medicine, Animals, DE, diet effect, Irs, insulin receptor substrate, C, control, Edem1, ER degradation-enhancing alpha-mannosidase-like 1, iNOS, inducible NO-synthase, NO, nitric oxide, business.industry, Organic Chemistry, Chop, C/EBP homologous protein, Feeding Behavior, medicine.disease, Small intestine, Toll-Like Receptor 4, 030104 developmental biology, Endocrinology, Glucose, chemistry, lcsh:Biology (General), Dnajc3, DnaJ homolog subfamily C member 3, ER, endoplasmatic reticulum, Lipid Peroxidation, Steatohepatitis, business, Herpud1, homocysteine-responsive endoplasmatic reticulum-resident ubiquitin-like domain member 1 protein, 030217 neurology & neurosurgery, Biomarkers, Xbp1, X-box binding protein 1

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b173ea7738b5f0fbb2100e259fb20393Test
https://hdl.handle.net/11353/10.1172206Test

المؤلفون: Nikolaos Perakakis, Konstantinos Stefanakis, Christos S. Mantzoros

المصدر: Metabolism

مصطلحات موضوعية: Proteomics, HCC, Hepatocellular carcinoma, Cirrhosis, SWE, Shear wave elastography, Endocrinology, Diabetes and Metabolism, TM6SF2, Transmembrane 6 superfamily member 2, Disease, CK-18, Cytokeratin-18, GCKR, Glucokinase regulatory protein, HDACis, HDAC inhibitors, transcriptomics, HSI, Hepatic Steatosis index, 0302 clinical medicine, Endocrinology, DAG, Diacylglycerol, EPA, Eicosapentanoic acid, MRI-PDFF, Magnetic resonance imaging derived proton density fat fraction, PE, Phosphatidylethanolamine, lncRNA, Long noncoding RNA, CAP, Controlled attenuation parameter, IgG, Immunoglobulin G, NASH, NAFLD, Non-alcoholic fatty liver disease, Genomics, TGF, Transforming growth factor, DHA, Docosahexaenoic acid, GRS, Genetic risk score, CRP, C-reactive protein, DHEA, Dehydroepiandrosterone, DNMTis, DNA methylation inhibitors, medicine.medical_specialty, PDGF, Platelet-derived growth factor, NASH, non-alcoholic steatohepatitis, DZNep, 3-deazaneplanocin A, tRNA, Transport RNA, PLA2, Phospholipase A2, digestive system, Article, TG, Triglyceride, 03 medical and health sciences, IL-32, Interleukin 32, AUROC, Area under the receiver operator characteristics, Humans, Metabolomics, MS, Mass Spectrometry, SPM, Specialized pro-resolving mediator, nutritional and metabolic diseases, TOF, Time-of-flight, medicine.disease, Omics, AST, Aspartate transaminase, PNPLA3, Patatin-like phospholipase domain-containing-3, digestive system diseases, NAFL, Non-alcoholic fatty liver, 030104 developmental biology, FXR, Farnesoid X receptor, PTPRE, protein-tyrosine phosphatase epsilon, Steatohepatitis, IGF, Insulin growth factor, ROS, Reactive oxygen species, ACC, Acetyl-coA carboxylase, Liver Cirrhosis, 0301 basic medicine, F#, Fibrosis (score), LPE, Lysophosphatidylethanolamine, LSM, Liver stiffness measurement, IL-32, Interleukin-32, VCTE, Vibration-controlled transient elastography, Bioinformatics, glycomics, HAT, Histone acetyltransferase, Non-alcoholic Fatty Liver Disease, APRI, Aspartate aminotransferase to platelet ratio index, steatosis, FADS, Fatty acid desaturase, circRNA, Circular RNA, NFS, NAFLD fibrosis score, PUFA, Polyunsaturated fatty acid, SNP, Single nucleotide polymorphism, NAS, NAFLD activity score, medicine.diagnostic_test, Fatty liver, AA, Arachidonic acid, IL-10, Interleukin-10, SFA, Saturated fatty acids, Liver biopsy, LPC, Lysophosphatidylcholine, FIB-4, Fibrosis-4 score, IGFBP, Insulin growth factor binding protein, ApoE, Apolipoprotein E, GGT, Gamma-glutamyltransferase, ChREBP, Carbohydrate, responsive element-binding protein, MUFA, Monounsaturated fatty acid, PC, Phosphatidylcholine, 030209 endocrinology & metabolism, PPAR, Peroxisome proliferator-activated receptor, HFD, High fat diet, Internal medicine, medicine, Animals, MetS, Metabolic syndrome, IL-6, Interleukin-6, MRE, magnetic resonance elastography, SIRT, Sirtuin, SELDI, Surface-enhanced laser desorption/ionization, BMI, Body mas index, business.industry, HDAC, Histone deacetylase, WC, Waist circumference, ALT, Alanine aminotransferase, CHI3L1, Chitinase 3 Like 1, FFA, Free fatty acids, GWAS, Genome - wide association studies, epigenomics, HSD17B13, 17-b retinol dehydrogenase 13, miR, Micro RNA, lipidomics, 1H-MRS, Magnetic resonance imaging and proton spectroscopy, MBOAT7, Membrane bound O-acyltransferase domain-containing 7, Steatosis, business, OR, Odds ratio, T2DM, Type 2 Diabetes Mellitus

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29bb96bcd7fb056ebf01eec2214ad114Test
https://doi.org/10.1016/j.metabol.2020.154320Test

المؤلفون: Felix Stickel, Maria L. Balmer, Jeannine Joneli, Wolfgang Thormann, Alain M. Schoepfer, Jean-François Dufour

المصدر: Clinical Science (London, England : 1979)
Clinical science (London England : 1979)

مصطلحات موضوعية: Liver Cirrhosis, Male, Cirrhosis, BMI, body mass index, AST, aspartate aminotransferase, Serum Hyaluronic Acid, Chronic liver disease, Body Mass Index, Liver disease, 0302 clinical medicine, Blood serum, hepatic fibrosis, AdipoR, adiponectin receptor, Prospective Studies, Hyaluronic Acid, 2. Zero hunger, 0303 health sciences, Anthropometry, Liver Diseases, Fatty liver, General Medicine, Middle Aged, 3. Good health, TG, triacylglycerol, HOMA, homoeostasis model assessment, Elasticity Imaging Techniques, 030211 gastroenterology & hepatology, Female, non-alcoholic fatty liver disease (NAFLD), Research Article, Adult, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, ANCOVA, analysis of covariance, NASH, non-alcoholic steatohepatitis, S7, S3, metabolic syndrome, Bile Acids and Salts, Diagnosis, Differential, 03 medical and health sciences, Sex Factors, Internal medicine, ALT, alanine aminotransferase, medicine, Humans, 030304 developmental biology, Adiponectin, adiponectin, business.industry, cirrhosis, nutritional and metabolic diseases, chronic liver disease, medicine.disease, Fatty Liver, Endocrinology, Chronic Disease, Steatohepatitis, business, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57760eaf2f7c8755862836a259985d38Test
https://pubmed.ncbi.nlm.nih.gov/20524936Test