المؤلفون: Lucia Parlati, Catherine Postic, Marion Régnier, Hervé Guillou

المساهمون: LESUR, Hélène, Impact du métabolisme des acides gras des tissus adipeux et du foie sur l'insulinorésistance - - HepAdialogue2017 - ANR-17-CE14-0015 - AAPG2017 - VALID, Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Catholique de Louvain = Catholic University of Louvain (UCL), ToxAlim (ToxAlim), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Ecole d'Ingénieurs de Purpan (INPT - EI Purpan), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Toxicologie Intégrative & Métabolisme (ToxAlim-TIM), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3), Lucia Parlati and Catherine Postic received funding from the French association for the study of the liver (AFEF). Catherine Postic and Herve Guillou received funding from the Agence Nationale de la Recherche (ANR-17-CE14-0015Hepadialogue)., ANR-17-CE14-0015,HepAdialogue,Impact du métabolisme des acides gras des tissus adipeux et du foie sur l'insulinorésistance(2017), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP)

المصدر: JHEP Reports
JHEP Reports Innovation in Hepatology
JHEP Reports Innovation in Hepatology, 2021, 3 (6), pp.100346. ⟨10.1016/j.jhepr.2021.100346⟩
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (6), pp.100346. ⟨10.1016/j.jhepr.2021.100346⟩

مصطلحات موضوعية: HFD, high-fat diet, SREBP-1c, [SDV]Life Sciences [q-bio], Disease, Review, ACC, acetyl-CoA carboxylase, ASK1, apoptosis signal-regulating kinase 1, Chronic liver disease, Bioinformatics, ChREBP, carbohydrate responsive element–binding protein, PPARα, NEFA, TNF-α, tumour necrosis factor-α, 0302 clinical medicine, Fibrosis, Immunology and Allergy, Medicine, IL-, interleukin, VLDL, very low-density lipoprotein, 0303 health sciences, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, NEFA, non-esterified fatty acid, Fatty liver, Gastroenterology, NASH, lipotoxicity, FAS, fatty acid synthase, animal models, 3. Good health, [SDV] Life Sciences [q-bio], PY, persons/years, Lipotoxicity, FXR, Saturated fatty acid, JNK, c-Jun N-terminal kinase, 030211 gastroenterology & hepatology, LXR, CAP, controlled attenuation parameter, HSL, hormone-sensitive lipase, HSC, hepatic stellate cells, GGT, gamma glutamyltransferase, NAFLD, non-alcoholic fatty liver disease, ChREBP, NASH, non-alcoholic steatohepatitis, SFA, saturated fatty acid, TCA, tricarboxylic acid, Phf2, histone demethylase plant homeodomain finger 2, digestive system, 03 medical and health sciences, glucotoxicity, FXR, farnesoid X receptor, NAFLD, FFA, free fatty acid, Internal Medicine, RCT, randomised controlled trial, Liver X receptor, PPARa, 030304 developmental biology, FGF21, fibroblast growth factor-21, MCD, methionine- and choline-deficient, HVPG, hepatic venous pressure gradient, Hepatology, business.industry, PUFAs, polyunsaturated fatty acids, nutritional and metabolic diseases, TLR4, Toll-like receptor 4, SCD1, stearoyl-CoA desaturase-1, medicine.disease, digestive system diseases, PPARα, peroxisome proliferator-activated receptor-α, SREBP-1c, sterol regulatory element–binding protein-1c, Steatosis, LXR, liver X receptor, business, HCC, hepatocellular carcinoma, MUFA, monounsaturated fatty acids, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba31673956635c337dc60791ff712432Test
https://pubmed.ncbi.nlm.nih.gov/34667947Test

المؤلفون: Manuel Romero-Gómez, Patrizia Carrieri, Mattias Ekstedt, Shira Zelber-Sagi, Katja Novak, Vlad Ratziu, Quentin M. Anstee, Frank Tacke, Adam Palayew, Jeffrey V. Lazarus, Helena Cortez-Pinto, Giulio Marchesini

المساهمون: Instituto de Salud Global - Institute For Global Health [Barcelona] (ISGlobal), University of Barcelona, McGill University = Université McGill [Montréal, Canada], Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale (SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Linköping University (LIU), Alma Mater Studiorum University of Bologna (UNIBO), Istituto di ricovero e cura a carattere scientifico Azienda Ospedaliera Universitaria 'San Martino' (IRCCS AOU San Martino), University Medical Centre Ljubljana [Ljubljana, Slovenia] (UMCL), Sorbonne Université - Faculté de Médecine (SU FM), Sorbonne Université (SU), CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centro de Investigación Biomédica en Red en el Área temática de Enfermedades Hepáticas y Digestivas (CIBERehd), Liver Unit, Clínica Universitaria, CIBER-EHD, Hospital Universitario Virgen del Rocío [Sevilla], Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], University of Haifa [Haifa], Universidade de Lisboa (ULISBOA), Newcastle University [Newcastle], Lazarus J.V., Palayew A., Carrieri P., Ekstedt M., Marchesini G., Novak K., Ratziu V., Romero-Gomez M., Tacke F., Zelber-Sagi S., Cortez-Pinto H., Anstee Q.M., EASL International Liver Foundation, Gilead Sciences, Allergan Foundation, Bristol-Myers Squibb, Pfizer, Resoundant, Intercept Pharmaceuticals, Genfit, Ministerio de Ciencia, Innovación y Universidades (España), Instituto de Salud Carlos III, European Commission, Generalitat de Catalunya, NIHR Biomedical Research Centre (UK), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Universidade de Lisboa = University of Lisbon (ULISBOA), Repositório da Universidade de Lisboa, Gestionnaire, Hal Sorbonne Université

المصدر: JHEP Reports Innovation in Hepatology
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (2), pp.100234. ⟨10.1016/j.jhepr.2021.100234⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
JHEP Reports
JHEP Reports, Vol 3, Iss 2, Pp 100234-(2021)

مصطلحات موضوعية: ESPEN, type 2 diabetes mellitus, EASL, European Association for the Study of the Liver, [SDV]Life Sciences [q-bio], Disease, Multiple joint correspondence analysi, WHO, 0302 clinical medicine, Non-alcoholic fatty liver disease, Liver health, Multiple joint correspondence analysis, Policy preparedness, Health policy, Metabolic-associated fatty liver disease, Non-alcoholic steatohepatitis, Europe, Multidisciplinary approach, EASD, European Association for the Study of Diabetes, European Association for the Study of Diabetes, Epidemiology, Immunology and Allergy, Medicine, European Association for the Study of Obesity, European Society of Clinical Nutrition and Metabolism, EEA, EASO, European Association for the Study of Obesity, media_common, Gastroenterology, NASH, food and beverages, ESPEN, European Society of Clinical Nutrition and Metabolism, 3. Good health, [SDV] Life Sciences [q-bio], 030220 oncology & carcinogenesis, Preparedness, 030211 gastroenterology & hepatology, Research Article, European Association for the Study of the Liver, EEA, European Economic Area, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, EASD, NASH, non-alcoholic steatohepatitis, multiple correspondence analysis, T2DM, Gastroenterology and Hepatology, EASL, World Health Organization, digestive system, WHO, World Health Organization, European Economic Area, 03 medical and health sciences, Environmental health, EU, European Union, NAFLD, Gastroenterologi, Internal Medicine, media_common.cataloged_instance, European Union, lcsh:RC799-869, European union, MCA, multiple correspondence analysis, Hepatology, business.industry, Public health, MCA, nutritional and metabolic diseases, non-alcoholic fatty liver disease, T2DM, type 2 diabetes mellitus, medicine.disease, Obesity, digestive system diseases, EASO, lcsh:Diseases of the digestive system. Gastroenterology, business, EU, Non-alcoholic steatohepatiti

وصف الملف: ELETTRONICO; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::237265ca3a905978c88b2731dd069191Test
https://hal.sorbonne-universite.fr/hal-03174867Test

المؤلفون: F. Tuccillo, Joseph L. Evans, Antonella Borrelli, Franco M. Buonaguro, Ira D. Goldfine, P. Bonelli, Aldo Mancini

المصدر: Redox Biology, Vol 15, Iss C, Pp 467-479 (2018)
Redox Biology

مصطلحات موضوعية: Cirrhosis, HCC, Hepatocellular carcinoma, MnSOD, Manganese superoxide dismutase, Review Article, ecSOD, Extracellular Cu/ZnSOD, Biochemistry, Antioxidants, GIT, Gastrointestinal tract, 0302 clinical medicine, Fibrosis, MS, Metabolic syndrome, GLP-1, Glucagon-like peptide-1, LPS, Lipopolysaccharide, lcsh:QH301-705.5, Interventions, DASH, Drug-associated steatohepatitis, SSAO, Semicarbazide-sensitive amine oxidase, NKT, Natural killer T, Liver Neoplasms, NAFLD, Non-alcoholic fatty liver disease, PAMPs, Pathogen-associated molecular patterns (PAMPs), LPL, Lipoprotein lipase, PNPLA3, Patatin-like phospholipase 3, 030211 gastroenterology & hepatology, SCD1, Stearoyl-coenzyme A desaturase 1, AST, Aspartate aminotransferase, PGC-1α, Coactivator peroxisome proliferator-activated receptor-γ-1α, INT-747, Obeticholic acid (OCA), lcsh:Medicine (General), NADH, Nicotinamide adenine dinucleotide, LPB, Lipopolysaccharide-binding protein, Carcinoma, Hepatocellular, FIAF, Fasting-induced adipose factor, CS + WR, Cold storage and warm reperfusion, GF, Germ-free, FADH, Flavin adenine dinucleotide, NO, Nitric oxide, digestive system, CCR2/CCR5, C-C chemokine receptor types 2 and 5, 03 medical and health sciences, Manganese superoxide dismutase, Humans, CD14, Cluster of differentiation 14, NASH, Non-alcoholic steatohepatitis, Probiotics, nutritional and metabolic diseases, medicine.disease, VLX103, Venlafaxine-103, digestive system diseases, PIVENS, Pioglitazone versus Vitamin E versus Placebo, 030104 developmental biology, chemistry, PASH, PNPLA3-associated steatohepatitis, FXR, Farnesoid X receptor, CASH, Chemotherapy-associated steatohepatitis, LOXL, Lysyl oxidase and lysyl oxidase-like, Steatohepatitis, Reactive Oxygen Species, Mkt, Market, ROS, Reactive oxygen species, TZDs, Thiazolidinediones, 0301 basic medicine, ETC, Respiratory electron transport chain, Clinical Biochemistry, VAP-1, Vascular adhesion protein-1, PXS-4728A, SSAO/VAP-1 inhibitor BI 1467335, HVPG, Hepatic venous pressure gradient, •OH, Hydroxyl free radicals, HPC, Primary hepatic carcinoma, Chronic liver disease, SOD, Superoxide dismutase, FGF21, Fibroblast growth factor 21, aa, Amino acid, chemistry.chemical_compound, BASH, Both alcoholic and non-alcoholic liver disease, Non-alcoholic Fatty Liver Disease, H2, Molecular hydrogen, lcsh:R5-920, NAS, NAFLD activity score, medicine.diagnostic_test, NN2211, Liraglutide, O2, Molecular oxygen, Fatty liver, Elafibranor, Obeticholic acid, Drugs, ER, Estrogen receptor, IL-10, Interleukin-10, Liver, Liver biopsy, JNK, c-Jun N-terminal kinase, ASK1, Apoptosis signal- regulating kinase 1, Cu/ZnSOD, Copper/zinc superoxide dismutase, RG-125 AZD4076, N-acetylgalactosamine (GalNAc)-conjugated anti-miR-103/107 oligonucleotide, TLR, Toll-like receptor, H. pilory, Helicobacter pylori, HSCs, Hepatic stellate cells, PPAR, Peroxisome proliferator-activated receptor, medicine, ATP, Adenosine 5c-triphosphate, IL-6, Interleukin-6, MDA, Malondialdehyde, γgt, Gamma-glutamyl transferase, business.industry, Organic Chemistry, ALT, Alanine aminotransferase, TNF, Tumor necrosis factor, NF-κB, Nuclear factor kappa, O2·–, Superoxide anion, FGF19, Fibroblast growth factor 19, Gastrointestinal Microbiome, DPP-4 inhibitor, Dipeptidyl peptidase 4 inhibitor, FDA, Food and drug administration, Oxidative Stress, CVC, Cenicriviroc, lcsh:Biology (General), FFA, Free fatty acids, Cancer research, NAP, H. pylori-induced neutrophil-activating protein, Saroglitazar-ZYH1, [(S)-α-ethoxy-4-{2-[2-methyl-5-(4-methylthio) phenyl)]-1H-pyrrol-1-yl]-ethoxy})-benzenepropanoic acid magnesium salt], business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2419fc2467afc0fef89a4f91dd16f4cTest
http://www.sciencedirect.com/science/article/pii/S2213231717309291Test

المؤلفون: Nikolaos Perakakis, Konstantinos Stefanakis, Christos S. Mantzoros

المصدر: Metabolism

مصطلحات موضوعية: Proteomics, HCC, Hepatocellular carcinoma, Cirrhosis, SWE, Shear wave elastography, Endocrinology, Diabetes and Metabolism, TM6SF2, Transmembrane 6 superfamily member 2, Disease, CK-18, Cytokeratin-18, GCKR, Glucokinase regulatory protein, HDACis, HDAC inhibitors, transcriptomics, HSI, Hepatic Steatosis index, 0302 clinical medicine, Endocrinology, DAG, Diacylglycerol, EPA, Eicosapentanoic acid, MRI-PDFF, Magnetic resonance imaging derived proton density fat fraction, PE, Phosphatidylethanolamine, lncRNA, Long noncoding RNA, CAP, Controlled attenuation parameter, IgG, Immunoglobulin G, NASH, NAFLD, Non-alcoholic fatty liver disease, Genomics, TGF, Transforming growth factor, DHA, Docosahexaenoic acid, GRS, Genetic risk score, CRP, C-reactive protein, DHEA, Dehydroepiandrosterone, DNMTis, DNA methylation inhibitors, medicine.medical_specialty, PDGF, Platelet-derived growth factor, NASH, non-alcoholic steatohepatitis, DZNep, 3-deazaneplanocin A, tRNA, Transport RNA, PLA2, Phospholipase A2, digestive system, Article, TG, Triglyceride, 03 medical and health sciences, IL-32, Interleukin 32, AUROC, Area under the receiver operator characteristics, Humans, Metabolomics, MS, Mass Spectrometry, SPM, Specialized pro-resolving mediator, nutritional and metabolic diseases, TOF, Time-of-flight, medicine.disease, Omics, AST, Aspartate transaminase, PNPLA3, Patatin-like phospholipase domain-containing-3, digestive system diseases, NAFL, Non-alcoholic fatty liver, 030104 developmental biology, FXR, Farnesoid X receptor, PTPRE, protein-tyrosine phosphatase epsilon, Steatohepatitis, IGF, Insulin growth factor, ROS, Reactive oxygen species, ACC, Acetyl-coA carboxylase, Liver Cirrhosis, 0301 basic medicine, F#, Fibrosis (score), LPE, Lysophosphatidylethanolamine, LSM, Liver stiffness measurement, IL-32, Interleukin-32, VCTE, Vibration-controlled transient elastography, Bioinformatics, glycomics, HAT, Histone acetyltransferase, Non-alcoholic Fatty Liver Disease, APRI, Aspartate aminotransferase to platelet ratio index, steatosis, FADS, Fatty acid desaturase, circRNA, Circular RNA, NFS, NAFLD fibrosis score, PUFA, Polyunsaturated fatty acid, SNP, Single nucleotide polymorphism, NAS, NAFLD activity score, medicine.diagnostic_test, Fatty liver, AA, Arachidonic acid, IL-10, Interleukin-10, SFA, Saturated fatty acids, Liver biopsy, LPC, Lysophosphatidylcholine, FIB-4, Fibrosis-4 score, IGFBP, Insulin growth factor binding protein, ApoE, Apolipoprotein E, GGT, Gamma-glutamyltransferase, ChREBP, Carbohydrate, responsive element-binding protein, MUFA, Monounsaturated fatty acid, PC, Phosphatidylcholine, 030209 endocrinology & metabolism, PPAR, Peroxisome proliferator-activated receptor, HFD, High fat diet, Internal medicine, medicine, Animals, MetS, Metabolic syndrome, IL-6, Interleukin-6, MRE, magnetic resonance elastography, SIRT, Sirtuin, SELDI, Surface-enhanced laser desorption/ionization, BMI, Body mas index, business.industry, HDAC, Histone deacetylase, WC, Waist circumference, ALT, Alanine aminotransferase, CHI3L1, Chitinase 3 Like 1, FFA, Free fatty acids, GWAS, Genome - wide association studies, epigenomics, HSD17B13, 17-b retinol dehydrogenase 13, miR, Micro RNA, lipidomics, 1H-MRS, Magnetic resonance imaging and proton spectroscopy, MBOAT7, Membrane bound O-acyltransferase domain-containing 7, Steatosis, business, OR, Odds ratio, T2DM, Type 2 Diabetes Mellitus

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29bb96bcd7fb056ebf01eec2214ad114Test
https://doi.org/10.1016/j.metabol.2020.154320Test

المؤلفون: Yemi Oluboyede, Gulnar Fattakhova, Lorraine McSweeney, Luke Vale, Lynda C. Doward, Fiona Beyer, Clifford A. Brass, Quentin M. Anstee, Matthew Breckons, Laura Ternent, Maria-Magdalena Balp, Arun J. Sanyal

المصدر: JHEP Reports
JHEP Reports, Vol 2, Iss 3, Pp-(2020)

مصطلحات موضوعية: medicine.medical_treatment, Disease, Liver disease, 0302 clinical medicine, Immunology and Allergy, 030212 general & internal medicine, Non-alcoholic steatohepatitis, education.field_of_study, Gastroenterology, PRO, patient-reported outcome, LDSI, liver disease symptom index, 3. Good health, health-related quality of life, Cirrhosis, 030211 gastroenterology & hepatology, Patient-reported outcome, SF-36, short form health profile 36, Research Article, FDA, United States Food and Drug Administration, RI, researcher interpretation, HRQoL, health-related quality of life, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, SF-36, NASH, non-alcoholic steatohepatitis, Population, liver, digestive system, Support group, MS, multiple sclerosis, 03 medical and health sciences, Quality of life (healthcare), NAFLD, PHAQ, patient-reported outcome measurement information system health assessment questionnaire, Internal Medicine, medicine, NAFL, non-alcoholic fatty liver, CLDQ, chronic liver disease questionnaire, lcsh:RC799-869, Intensive care medicine, education, patient-reported outcome measures, Hepatology, business.industry, nutritional and metabolic diseases, medicine.disease, QoL, quality of life, Mental health, digestive system diseases, FIS, fatigue impact scale, PROM, patient-reported outcome measure, EMA, European Medicines Agency, COSMIN, The COnsensus-based Standards for the selection of health Measurement INstruments, lcsh:Diseases of the digestive system. Gastroenterology, business, LDQoL, liver disease quality of life questionnaire

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee751f2b6ffd99b10142118b951f0fcdTest
https://doi.org/10.1016/j.jhepr.2020.100099Test