نتائج البحث

1

Mechanistic insights into immune checkpoint inhibitor-related hypophysitis: a form of paraneoplastic syndrome

المؤلفون: Ryusaku Matsumoto, Masaaki Yamamoto, Genzo Iguchi, Shin Urai, Hidenori Fukuoka, Wataru Ogawa, Kentaro Suda, Hiroki Shichi, Keitaro Kanie, Yutaka Takahashi, Hironori Bando, Yasunori Fujita

المصدر: Cancer Immunology, Immunotherapy

مصطلحات موضوعية: Male, Cancer Research, Pro-Opiomelanocortin, Paraneoplastic Syndromes, Programmed Cell Death 1 Receptor, Autoimmunity, Hypopituitarism, Immune checkpoint inhibitor, medicine.disease_cause, B7-H1 Antigen, Mice, 0302 clinical medicine, Neoplasms, Immunology and Allergy, CTLA-4 Antigen, Corticotrophs, Immune Checkpoint Inhibitors, Aged, 80 and over, biology, Middle Aged, Oncology, 030220 oncology & carcinogenesis, Paraneoplastic syndrome, Female, Original Article, Immunotherapy, Antibody, hormones, hormone substitutes, and hormone antagonists, Adult, endocrine system, Hypophysitis, Immunology, 030209 endocrinology & metabolism, Adrenocorticotropic hormone, 03 medical and health sciences, Antigen, medicine, Animals, Humans, Aged, Retrospective Studies, business.industry, medicine.disease, biology.protein, Ectopic expression, Corticotropic cell, business, Adrenal Insufficiency

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3acc181a81511e7fe6b828ea748faa32Test
https://hdl.handle.net/20.500.14094/90008773Test

2

SAMHD1 expression is associated with low immune activation but not correlated with HIV‑1 DNA levels in CD4+ T cells of patients with HIV‑1

المؤلفون: Jie Li, Longteng Jin, Shanshan Huang, Chuanhua Gao, Changzhong Jin

المصدر: Molecular Medicine Reports

مصطلحات موضوعية: Adult, CD4-Positive T-Lymphocytes, Male, 0301 basic medicine, Cancer Research, HIV Infections, HIV-1 DNA, Biology, Biochemistry, Peripheral blood mononuclear cell, Gene Expression Regulation, Enzymologic, elite controllers, immune activation, SAM Domain and HD Domain-Containing Protein 1, 03 medical and health sciences, 0302 clinical medicine, Genetics, Humans, sterile α motif and histidine/aspartic acid domain-containing protein 1, Molecular Biology, Gene, Regulation of gene expression, Oncogene, Interferon-alpha, Articles, Middle Aged, Viral Load, Cell cycle, Reverse transcriptase, 030104 developmental biology, Anti-Retroviral Agents, Oncology, Apoptosis, 030220 oncology & carcinogenesis, DNA, Viral, Immunology, HIV-1, Leukocytes, Mononuclear, RNA, Viral, Molecular Medicine, Female, SAMHD1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::779b8ae7dcad85cf36332ff19bee6b43Test
https://doi.org/10.3892/mmr.2020.11153Test

3

Association of cancer progression with elevated expression of programmed cell death protein 1 ligand 1 by upper tract urothelial carcinoma and increased tumor-infiltrating lymphocyte density

المؤلفون: Kyoko Arai, Takao Kamai, Akinori Nukui, Minoru Kobayashi, Hideo Yuki, Takahiro Narimatsu, Yoshitatsu Fukabori, Toshiki Kijima, Ken-Ichiro Yoshida, Hideyuki Abe, Tsunehito Kambara, Hironori Betsunoh, Masahiro Yashi

المصدر: Cancer Immunology, Immunotherapy

مصطلحات موضوعية: Male, Cancer Research, Lymphocyte, Kidney, Nephroureterectomy, B7-H1 Antigen, Immune tolerance, 0302 clinical medicine, Tumor Microenvironment, Neutrophil-to-lymphocyte ratio (NLR), Immunology and Allergy, Stage (cooking), Aged, 80 and over, 0303 health sciences, Univariate analysis, Middle Aged, Prognosis, Kidney Neoplasms, Progression-Free Survival, Programmed cell death 1 ligand 1 (PD-L1), medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Upper tract urothelial carcinoma (UTUC), Disease Progression, Immunohistochemistry, Female, Original Article, Tumor-infiltrating lymphocyte (TIL), Adult, Immunology, 03 medical and health sciences, Lymphocytes, Tumor-Infiltrating, medicine, Humans, Aged, Retrospective Studies, 030304 developmental biology, Carcinoma, Transitional Cell, Tumor microenvironment, Ureteral Neoplasms, Tumor-infiltrating lymphocytes, business.industry, Cancer, medicine.disease, Cancer research, Neoplasm Grading, Ureter, business, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a089064114954a8996f5b69f009caefTest
https://doi.org/10.1007/s00262-020-02499-7Test

4

Exhaustion in tumor-infiltrating Mucosal-Associated Invariant T (MAIT) cells from colon cancer patients

المؤلفون: William Rodin, Filip Ahlmanner, Elinor Bexe Lindskog, Yvonne Wettergren, Louis Szeponik, Kamil Kajetan Zajt, Marianne Quiding Järbrink, Patrik Sundström

المصدر: Cancer Immunology, Immunotherapy

مصطلحات موضوعية: Adult, Male, Cancer Research, Exhaustion, Immunology, Programmed Cell Death 1 Receptor, Tim-3, Lymphocyte Activation, Mucosal-Associated Invariant T Cells, Flow cytometry, 03 medical and health sciences, 0302 clinical medicine, Immunity, Antigens, CD, Blocking antibody, PD-1, medicine, Tumor Microenvironment, Immunology and Allergy, Cytotoxic T cell, Humans, Secretion, Hepatitis A Virus Cellular Receptor 2, MAIT cell, 030304 developmental biology, Aged, Cell Proliferation, Aged, 80 and over, 0303 health sciences, Tumor microenvironment, CD39, medicine.diagnostic_test, Effector, Chemistry, Apyrase, Middle Aged, Colorectal cancer, In vitro, Phenotype, Oncology, Colonic Neoplasms, Cancer research, Cytokines, Original Article, Female, Biomarkers, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8846e11fd7e69e73f9cd68dd02080acTest
http://europepmc.org/articles/PMC8571139Test

5

Human leukocyte antigen I is significantly downregulated in patients with myxoid liposarcomas

المؤلفون: Masanori Hayashi, Tetsuro Yamagishi, Chihaya Imai, Hajime Umezu, Takashi Ariizumi, Yudai Murayama, Akira Ogose, Naoki Oike, Hiroyuki Kawashima, Hiroshi Hatano, Naoto Endo

المصدر: Cancer Immunology, Immunotherapy

مصطلحات موضوعية: Male, Cancer Research, Pathology, medicine.medical_treatment, Liposarcomas, B7-H1 Antigen, 0302 clinical medicine, HLA Antigens, Tumor Microenvironment, Immunology and Allergy, Programmed death ligand 1, Aged, 80 and over, 0303 health sciences, Middle Aged, Prognosis, Immunohistochemistry, Liposarcoma, Myxoid, Progression-Free Survival, Oncology, 030220 oncology & carcinogenesis, Original Article, Female, Human leukocyte antigen I, Adult, medicine.medical_specialty, Adolescent, Tumor immune microenvironment, Immunology, Down-Regulation, Human leukocyte antigen, Liposarcoma, Pleomorphic Liposarcoma, 03 medical and health sciences, Young Adult, Lymphocytes, Tumor-Infiltrating, medicine, Humans, neoplasms, 030304 developmental biology, Aged, Myxoid liposarcoma, Tumor-infiltrating lymphocytes, business.industry, Macrophages, Histocompatibility Antigens Class I, Immunotherapy, medicine.disease, body regions, CD163+ macrophages, business, CD163

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80679c1ba2c44a0ce4ca344ffcd402aeTest
http://europepmc.org/articles/PMC8571150Test

6

First-line treatment of advanced/metastatic melanoma with anti-PD-1 antibodies: multicenter experience in Poland

المصدر: Immunotherapy. 13:297-307

مصطلحات موضوعية: Adult, Male, Oncology, medicine.medical_specialty, Multivariate analysis, Drug-Related Side Effects and Adverse Reactions, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Immunology, Pembrolizumab, Antibodies, Monoclonal, Humanized, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Humans, Immunology and Allergy, Medicine, 030212 general & internal medicine, Stage (cooking), Adverse effect, Immune Checkpoint Inhibitors, Melanoma, Aged, Retrospective Studies, Aged, 80 and over, business.industry, Immunotherapy, Middle Aged, Prognosis, medicine.disease, Progression-Free Survival, Survival Rate, Clinical trial, Nivolumab, Treatment Outcome, 030220 oncology & carcinogenesis, Female, Poland, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75481f1f9c5cc0cca549a49f8bad084dTest
https://doi.org/10.2217/imt-2020-0217Test

7

Genetic profile of adult T‐cell leukemia/lymphoma in Okinawa: Association with prognosis, ethnicity, and HTLV‐1 strains

المؤلفون: Kazuho Morichika, Shugo Sakihama, Hiroaki Masuzaki, Sawako Nakachi, Jun-Nosuke Uchihara, Kennosuke Karube, Shingo Nakayama, Kazuko Sakai, Satoko Morishima, Kazuto Nishio, Masaki Hayashi, Rumiko Saito, Takeaki Tomoyose, Takuya Fukushima, Megumi Miyara, Takashi Miyagi, Kazuiku Ohshiro

المصدر: Cancer Science

مصطلحات موضوعية: 0301 basic medicine, Genetics, Genomics and Proteomics, Male, Cancer Research, RHOA, Genotyping Techniques, Kaplan-Meier Estimate, Gene mutation, medicine.disease_cause, Genetic analysis, 0302 clinical medicine, Japan, immune system diseases, hemic and lymphatic diseases, Ethnicity, Leukemia-Lymphoma, Adult T-Cell, geographical mutation heterogeneity, Aged, 80 and over, Mutation, Human T-lymphotropic virus 1, biology, High-Throughput Nucleotide Sequencing, General Medicine, Gene Products, tax, Genetic Profile, Middle Aged, Prognosis, Leukemia, Oncology, 030220 oncology & carcinogenesis, Original Article, Female, Adult, integrated clinico‐genetic analysis, DNA Copy Number Variations, Polymorphism, Single Nucleotide, Adult T-cell leukemia/lymphoma, 03 medical and health sciences, PRDM1, medicine, Biomarkers, Tumor, adult T‐cell leukemia/lymphoma, Humans, Aged, human T‐cell leukemia virus type I, Original Articles, medicine.disease, tax subgroup, HTLV-I Infections, Lymphoma, 030104 developmental biology, Immunology, biology.protein, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d517e8449311ef95a6ecc2bd5d2502d6Test
http://europepmc.org/articles/PMC7935801Test

8

High tumor mutational burden and T-cell activation are associated with long-term response to anti-PD1 therapy in Lynch syndrome recurrent glioblastoma patient

المؤلفون: Elena Anghileri, Junfei Zhao, Valeria Cuccarini, Gaetano Finocchiaro, Monica Patanè, Natalia Di Ianni, Marica Eoli, Tiziana Langella, Antonio Iavarone, Serena Pellegatta, Raul Rabadan, Bianca Pollo, Rosina Paterra

المصدر: Cancer Immunology, Immunotherapy. 70:831-842

مصطلحات موضوعية: Adult, Cancer Research, Biopsy, T-Lymphocytes, T cell, Programmed Cell Death 1 Receptor, Immunology, Neuroimaging, Germline, 03 medical and health sciences, 0302 clinical medicine, Immunophenotyping, Immune system, Exome Sequencing, Biomarkers, Tumor, Humans, Immunology and Allergy, Medicine, Molecular Targeted Therapy, Immune Checkpoint Inhibitors, Temozolomide, business.industry, medicine.disease, Colorectal Neoplasms, Hereditary Nonpolyposis, Combined Modality Therapy, Immunohistochemistry, Magnetic Resonance Imaging, Lynch syndrome, Treatment Outcome, medicine.anatomical_structure, Oncology, MSH2, Mutation, Retreatment, Cancer research, Female, Neoplasm Recurrence, Local, Nivolumab, Glioblastoma, business, 030215 immunology, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e9d6d866c397beb05c63097c4dbcb1Test
https://doi.org/10.1007/s00262-020-02769-4Test

9

An observational study of drug utilization and associated outcomes among adult patients diagnosed with BRAF‐mutant advanced melanoma treated with first‐line anti‐PD‐1 monotherapies or BRAF/MEK inhibitors in a community‐based oncology setting

المؤلفون: Charles Lance Cowey, Emilie Scherrer, April Beeks, Clemens Krepler, Marley Boyd, Kathleen M. Aguilar

المصدر: Cancer Medicine, Vol 9, Iss 21, Pp 7863-7878 (2020)
Cancer Medicine

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Cancer Research, Skin Neoplasms, Time Factors, Programmed Cell Death 1 Receptor, Medical Oncology, immunology, 0302 clinical medicine, Risk Factors, Medicine, Community Health Services, Molecular Targeted Therapy, Immune Checkpoint Inhibitors, Melanoma, Original Research, Community based, Aged, 80 and over, Middle Aged, MAP Kinase Kinase Kinases, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Progression-Free Survival, 030220 oncology & carcinogenesis, Female, Drug Utilization, Adult, Proto-Oncogene Proteins B-raf, medicine.medical_specialty, First line, Risk Assessment, survival, lcsh:RC254-282, 03 medical and health sciences, Internal medicine, Humans, Radiology, Nuclear Medicine and imaging, Protein Kinase Inhibitors, Advanced melanoma, Aged, Retrospective Studies, Adult patients, business.industry, target therapy, Clinical Cancer Research, biomarkers, Retrospective cohort study, 030104 developmental biology, Propensity score matching, Mutation, Observational study, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96fc6bc46c16e1f918585ef9a89a846dTest
https://doaj.org/article/ee976dd75d584d12914c8df2bc5510e8Test

10

TILs and Anti-PD1 Therapy: An Alternative Combination Therapy for PDL1 Negative Metastatic Cervical Cancer

المؤلفون: Huanhuan Yin, Cuihua Feng, Yujie Tan, Xiangling Sun, Wei Guo, Ruili Li

المصدر: Journal of Immunology Research, Vol 2020 (2020)
Journal of Immunology Research

مصطلحات موضوعية: Adult, Cytotoxicity, Immunologic, Oncology, medicine.medical_specialty, Multivariate analysis, Article Subject, Combination therapy, Programmed Cell Death 1 Receptor, Immunology, Uterine Cervical Neoplasms, Kaplan-Meier Estimate, B7-H1 Antigen, Immunophenotyping, 03 medical and health sciences, Lymphocytes, Tumor-Infiltrating, 0302 clinical medicine, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Biomarkers, Tumor, medicine, Overall survival, Humans, Immunology and Allergy, In patient, Molecular Targeted Therapy, Anti pd1, Immune Checkpoint Inhibitors, Objective response, Metastatic cervical cancer, Aged, business.industry, General Medicine, Middle Aged, RC581-607, Prognosis, Magnetic Resonance Imaging, Treatment Outcome, 030220 oncology & carcinogenesis, Cytokines, Female, Immunologic diseases. Allergy, Tomography, X-Ray Computed, business, Research Article, 030215 immunology

وصف الملف: text/xhtml

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::721b2d90497b5fff7641c5df3560f9cdTest
https://doi.org/10.1155/2020/8345235Test

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