نتائج البحث

1

NRP1 and MMP9 are dual targets of RNA‐binding protein QKI5 to alter VEGF‐R/ NRP1 signalling in trophoblasts in preeclampsia

المؤلفون: Xingyu Yang, Biwei He, Dan Chen, Weiwei Cheng

المصدر: Journal of Cellular and Molecular Medicine

مصطلحات موضوعية: 0301 basic medicine, Adult, medicine.medical_treatment, MMP9, preeclampsia, 03 medical and health sciences, Mice, 0302 clinical medicine, Pre-Eclampsia, In vivo, Cell Movement, Pregnancy, Neuropilin 1, medicine, NRP1, QKI5, Animals, Humans, Secretion, Cell Proliferation, Cell growth, Chemistry, Growth factor, Trophoblast, RNA-Binding Proteins, Cell Biology, Original Articles, trophoblast, Hedgehog signaling pathway, Neuropilin-1, Cell biology, Trophoblasts, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Receptors, Vascular Endothelial Growth Factor, Matrix Metalloproteinase 9, 030220 oncology & carcinogenesis, Case-Control Studies, Molecular Medicine, Original Article, Female, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4918015cab186bc5d21a6f1f0b02e93Test
http://europepmc.org/articles/PMC8184681Test

2

BMP9 attenuates occurrence of venous malformation by maintaining endothelial quiescence and strengthening vessel walls via SMAD1/5/ID1/α-SMA pathway

المؤلفون: Zhi Yang, Yefei Wang, Shengfang Ge, Jie Yang, Peng Li, Yongyun Li, Jiahao Shi, Xianqun Fan, Qingfeng Shang, Renbing Jia

المصدر: Journal of Molecular and Cellular Cardiology. 147:92-107

مصطلحات موضوعية: Adult, Inhibitor of Differentiation Protein 1, Male, Smad5 Protein, 0301 basic medicine, Small interfering RNA, Adolescent, Endothelium, Myocytes, Smooth Muscle, Down-Regulation, Neovascularization, Physiologic, Mice, Transgenic, 030204 cardiovascular system & hematology, Gene mutation, Muscle, Smooth, Vascular, Umbilical vein, Smad1 Protein, Veins, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Cell Movement, Transforming Growth Factor beta, Growth Differentiation Factor 2, Human Umbilical Vein Endothelial Cells, medicine, Animals, Humans, Child, Receptor, Molecular Biology, Aged, Cell Proliferation, Tube formation, Chemistry, Middle Aged, Actins, Cell biology, Mice, Inbred C57BL, Blot, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Child, Preschool, Female, Desmin, Cardiology and Cardiovascular Medicine, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b60c7d559d937bd7835c767a7014e8aaTest
https://doi.org/10.1016/j.yjmcc.2020.07.010Test

3

LncRNA EGOT decreases breast cancer cell viability and migration via inactivation of the Hedgehog pathway

المؤلفون: Juan Peng, Guobing Chen, Li Li, Shuang Qiu, Jumin Chen, Jia Liu, Jianjun Wang, Kunxian Yang

المصدر: FEBS Open Bio, Vol 10, Iss 5, Pp 817-826 (2020)
FEBS Open Bio

مصطلحات موضوعية: 0301 basic medicine, Purmorphamine, Adult, China, cell migration, Cell Survival, Gene Expression, Breast Neoplasms, Zinc Finger Protein GLI1, General Biochemistry, Genetics and Molecular Biology, Hedgehog pathway, 03 medical and health sciences, 0302 clinical medicine, breast cancer, GLI1, Cell Movement, Cell Line, Tumor, Humans, Hedgehog Proteins, Viability assay, lcsh:QH301-705.5, Research Articles, Protein Patched Homolog 1, Membrane Glycoproteins, biology, Cell growth, Chemistry, Cell migration, Middle Aged, Hedgehog signaling pathway, Cell biology, Gene Expression Regulation, Neoplastic, Patched-1 Receptor, Smoothened Receptor, 030104 developmental biology, cell proliferation, lcsh:Biology (General), 030220 oncology & carcinogenesis, lncRNA EGOT, biology.protein, Female, RNA, Long Noncoding, Carrier Proteins, Research Article, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8efdfe5bdf41ca0a0aa02aade0c72812Test
https://doaj.org/article/256a7c6b341c4317aa16ce6fdc0008b2Test

4

Inactivation of the AMPK–GATA3–ECHS1 Pathway Induces Fatty Acid Synthesis That Promotes Clear Cell Renal Cell Carcinoma Growth

المؤلفون: Wei Dong Zang, Rui Zhao, Bo Dai, Jian-Yuan Zhao, Shu Xian Zhou, Qian Zhou, Guo Hai Shi, Fu Jiang Xu, Xuan Zhang, Yi Jun Shen, Yuan-Yuan Qu, Wenhao Xu, Hai Liang Zhang, Yao Zhu, Wei Xu, Yan Lin, Yiping Zhu, Kun Chang, Ning Shao, Cheng Tao Han, Dingwei Ye, Shimin Zhao

المصدر: Cancer Research. 80:319-333

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Carcinogenesis, mTORC1, AMP-Activated Protein Kinases, Kidney, Nephrectomy, chemistry.chemical_compound, 0302 clinical medicine, Cell Movement, ECHS1, Enoyl-CoA Hydratase, Aged, 80 and over, Mice, Knockout, Chemistry, Fatty Acids, Middle Aged, Prognosis, Kidney Neoplasms, Progression-Free Survival, Gene Expression Regulation, Neoplastic, Oncology, 030220 oncology & carcinogenesis, Female, Signal Transduction, Adult, Down-Regulation, GATA3 Transcription Factor, Mechanistic Target of Rapamycin Complex 1, Young Adult, 03 medical and health sciences, Downregulation and upregulation, Cell Line, Tumor, medicine, Animals, Humans, Protein kinase A, Carcinoma, Renal Cell, Fatty acid synthesis, Aged, Cell Proliferation, Cell growth, Lipogenesis, AMPK, medicine.disease, Clear cell renal cell carcinoma, HEK293 Cells, 030104 developmental biology, Cancer research, Amino Acids, Branched-Chain

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::483ab17f7013255ae83ede71f21dc08cTest
https://doi.org/10.1158/0008-5472.can-19-1023Test

5

MicroRNA-203 inhibits epithelial-mesenchymal transition, migration, and invasion of renal cell carcinoma cells via the inactivation of the PI3K/AKT signaling pathway by inhibiting CAV1

المؤلفون: Ning Han, Hui Wang, Hai Li

المصدر: Cell Adhesion & Migration, Vol 14, Iss 1, Pp 227-241 (2020)
Cell Adhesion & Migration
article-version (VoR) Version of Record

مصطلحات موضوعية: 0301 basic medicine, Caveolin 1, pi3k/akt signaling, migration, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, Cell Movement, Chemistry, lcsh:Cytology, Cell Cycle, apoptosis, Cell cycle, Middle Aged, invasion, Kidney Neoplasms, Up-Regulation, Gene Expression Regulation, Neoplastic, 030220 oncology & carcinogenesis, Disease Progression, Research Article, Research Paper, Signal Transduction, microrna-203, Adult, renal cell carcinoma, Epithelial-Mesenchymal Transition, proliferation, Down-Regulation, epithelial-mesenchymal transformation, 03 medical and health sciences, Cellular and Molecular Neuroscience, Young Adult, Cell Line, Tumor, microRNA, Gene silencing, Humans, Neoplasm Invasiveness, Epithelial–mesenchymal transition, Gene Silencing, lcsh:QH573-671, Carcinoma, Renal Cell, PI3K/AKT/mTOR pathway, Aged, Cell Proliferation, cav1, Cell growth, Akt/PKB signaling pathway, Cell Biology, MicroRNAs, 030104 developmental biology, Apoptosis, Cancer research, Proto-Oncogene Proteins c-akt

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ca00ebca866fb90b2e28c4990cf4151Test
https://doaj.org/article/965824f69d474fe8bcddc36c3ee54b94Test

6

Long non-coding RNA UBE2CP3 enhances HCC cell secretion of VEGFA and promotes angiogenesis by activating ERK1/2/HIF-1α/VEGFA signalling in hepatocellular carcinoma

المؤلفون: Pan Li, Hongwei Liu, Yu Wang, Yan-Wei Hu, Jing Chen, Jiehua Li, Shun-wang Cao, Lei Zheng, Jinduan Lin, Qian Wang, Jumei Liu

المصدر: Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-13 (2018)

مصطلحات موضوعية: 0301 basic medicine, CD31, Male, Vascular Endothelial Growth Factor A, Cancer Research, Angiogenesis, Cell, Chick Embryo, Metastasis, Mice, 0302 clinical medicine, Nude mouse, Cell Movement, Neoplasm Metastasis, Tube formation, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, biology, Neovascularization, Pathologic, Chemistry, Liver Neoplasms, Middle Aged, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Immunohistochemistry, Gene Expression Regulation, Neoplastic, Vascular endothelial growth factor A, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Female, RNA, Long Noncoding, Signal Transduction, Adult, Carcinoma, Hepatocellular, Models, Biological, lcsh:RC254-282, 03 medical and health sciences, Cell Line, Tumor, Long non-coding RNA, UBE2CP3, HCC, Angiogenesis, ERK, VEGFA, Co-culture, medicine, Animals, Humans, Aged, Cell Proliferation, Oncogene, medicine.disease, biology.organism_classification, Hypoxia-Inducible Factor 1, alpha Subunit, digestive system diseases, 030104 developmental biology, Cancer research, Neoplasm Grading

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423e5b9d8ed6ebd2a1fd4b596a467c77Test
http://link.springer.com/article/10.1186/s13046-018-0727Test-1

7

Downregulation of MiR-203a Disinhibits Bmi1 and Promotes Growth and Proliferation of Keratinocytes in Cholesteatoma

المؤلفون: Xuejun Jiang, Lian Hui, Jian Zang, Bo Yang, Ning Yang

المصدر: International Journal of Medical Sciences

مصطلحات موضوعية: Adult, Keratinocytes, Male, 0301 basic medicine, Adolescent, p-Akt, Apoptosis, macromolecular substances, Cell Line, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Cell Movement, microRNA-203a, microRNA, otorhinolaryngologic diseases, Humans, Gene silencing, Child, Cholesteatoma, Protein kinase B, Aged, Cell Proliferation, Polycomb Repressive Complex 1, Reporter gene, Chemistry, Cell growth, General Medicine, Middle Aged, B-cell specific moloney murine leukemia virus insertion site 1 (Bmi1), Gene Expression Regulation, Neoplastic, MicroRNAs, HaCaT, 030104 developmental biology, Cell culture, 030220 oncology & carcinogenesis, Cancer research, Female, Proto-Oncogene Proteins c-akt, Research Paper, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f76b4eaa55ba65de6c957d064675d21dTest
https://doi.org/10.7150/ijms.22410Test

8

SREBP1 promotes the invasion of colorectal cancer accompanied upregulation of MMP7 expression and NF-κB pathway activation

المؤلفون: Tianyue Yang, Xinyi Liu, Huifen Zhu, Shu-Lin Liu, Binbin Liu, Xinjue Shi, Xianxiu Nan, Xiaoqin Mu, Bing-Qing Yao, Yuyan Gao, Yiting Hu

المصدر: BMC Cancer, Vol 19, Iss 1, Pp 1-8 (2019)
BMC Cancer

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Cancer Research, Angiogenesis, lcsh:RC254-282, NF-κB, Metastasis, Small hairpin RNA, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Tumor budding, Invasion, Cell Movement, Cell Line, Tumor, Genetics, medicine, Humans, Phosphorylation, Aged, Neoplasm Staging, Neovascularization, Pathologic, Chemistry, MMP7, NF-kappa B, Cell migration, Middle Aged, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, CRC, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Oncology, Cell culture, 030220 oncology & carcinogenesis, Matrix Metalloproteinase 7, Cancer research, Human umbilical vein endothelial cell, Female, Neoplasm Grading, SREBP1, Colorectal Neoplasms, Reactive Oxygen Species, Sterol Regulatory Element Binding Protein 1, Signal Transduction, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ea3ca3ec14d1232d6965ff307d47143Test
http://link.springer.com/article/10.1186/s12885-019-5904-xTest

9

Curcumin induces apoptosis in JAK2‐mutated cells by the inhibition of JAK2/STAT and mTORC1 pathways

المؤلفون: Carmen Fava, Jessica Petiti, Valentina Rosso, Barbara Pergolizzi, Chiara Calabrese, Antonio Cartellà, Enrico Bracco, Daniela Cilloni, Lucrezia Pironi, Cristina Panuzzo, Tiziana Beltramo, Marco Lo Iacono, Elisabetta Signorino

المصدر: Journal of Cellular and Molecular Medicine

مصطلحات موضوعية: Male, 0301 basic medicine, Myeloid, JAK/STAT, JAK2 V617F, Myeloproliferative neoplasms, curcumin, mTORC1, Apoptosis, chemistry.chemical_compound, 0302 clinical medicine, Cell Movement, hemic and lymphatic diseases, Tumor Cells, Cultured, Phosphorylation, Aged, 80 and over, Chemistry, JAK-STAT signaling pathway, Middle Aged, Gene Expression Regulation, Neoplastic, STAT Transcription Factors, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Molecular Medicine, Female, Original Article, Signal Transduction, Adult, Curcumin, Antineoplastic Agents, Mechanistic Target of Rapamycin Complex 1, stat, Young Adult, 03 medical and health sciences, Biomarkers, Tumor, medicine, Humans, Protein kinase B, PI3K/AKT/mTOR pathway, Aged, Cell Proliferation, Myeloproliferative Disorders, Original Articles, Cell Biology, Janus Kinase 2, 030104 developmental biology, Case-Control Studies, Mutation, Leukocytes, Mononuclear, Cancer research, Leukemia, Erythroblastic, Acute, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1264998e45c4406bd769069e121e7a2Test
https://doi.org/10.1111/jcmm.14326Test

10

Long Intergenic Non-Protein-Coding RNA 01138 Accelerates Tumor Growth and Invasion in Gastric Cancer by Regulating miR-1273e

المؤلفون: Jin-Na Zhang, Jue-Lei Wang, Guang-Xian Dou, Ping Wang, Guang-Bin Sun

المصدر: Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e2fc834bdfba67c8cdafd93f3004e9Test
https://doi.org/10.12659/msm.914248Test

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