نتائج البحث

المساهمون: Institut d'Histoire et de Philosophie des Sciences et des Techniques (IHPST), Université Paris 1 Panthéon-Sorbonne (UP1)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Blood
Blood, American Society of Hematology, 2021, 137 (24), pp.3390-3402. ⟨10.1182/blood.2020008729⟩

مصطلحات موضوعية: Adult, Male, MAPK/ERK pathway, CCR2, Myeloid, Cell Survival, MAP Kinase Signaling System, [SDV]Life Sciences [q-bio], Immunology, Chronic myelomonocytic leukemia, Biochemistry, Monocytes, 03 medical and health sciences, Chemokine receptor, 0302 clinical medicine, hemic and lymphatic diseases, medicine, Humans, MCL1, Extracellular Signal-Regulated MAP Kinases, Autocrine signalling, Protein Kinase Inhibitors, Aged, 030304 developmental biology, Aged, 80 and over, 0303 health sciences, Kinase, Chemistry, [SHS.PHIL]Humanities and Social Sciences/Philosophy, Leukemia, Myelomonocytic, Chronic, Blood Proteins, Cell Biology, Hematology, Middle Aged, medicine.disease, Xenograft Model Antitumor Assays, 3. Good health, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cancer research, Cytokines, Myeloid Cell Leukemia Sequence 1 Protein, Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a876fc49ce5e247d9cb91a3a300a22Test
https://doi.org/10.1182/blood.2020008729Test

5

TRIM21 drives intervertebral disc degeneration induced by oxidative stress via mediating HIF-1α degradation

المؤلفون: Changwei Li, Jiancheng Zheng, Leilei Chang, Xingkai Zhang, Lianfu Deng, Xiaogang Bao

المصدر: Biochemical and Biophysical Research Communications. 555:46-53

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Nucleus Pulposus, Adolescent, Biophysics, Intervertebral Disc Degeneration, Degeneration (medical), Oxidative phosphorylation, medicine.disease_cause, Biochemistry, Rats, Sprague-Dawley, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Ubiquitin, Downregulation and upregulation, medicine, Animals, Humans, Molecular Biology, Cells, Cultured, Aged, biology, Chemistry, Intervertebral disc, Hydrogen Peroxide, Cell Biology, Middle Aged, Hypoxia-Inducible Factor 1, alpha Subunit, Ubiquitin ligase, Cell biology, Oxidative Stress, 030104 developmental biology, medicine.anatomical_structure, Ribonucleoproteins, 030220 oncology & carcinogenesis, Disc degeneration, biology.protein, Female, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1f9723c47a8babbaba448cb61e293abTest
https://doi.org/10.1016/j.bbrc.2021.03.088Test

6

NRP1 and MMP9 are dual targets of RNA‐binding protein QKI5 to alter VEGF‐R/ NRP1 signalling in trophoblasts in preeclampsia

المؤلفون: Xingyu Yang, Biwei He, Dan Chen, Weiwei Cheng

المصدر: Journal of Cellular and Molecular Medicine

مصطلحات موضوعية: 0301 basic medicine, Adult, medicine.medical_treatment, MMP9, preeclampsia, 03 medical and health sciences, Mice, 0302 clinical medicine, Pre-Eclampsia, In vivo, Cell Movement, Pregnancy, Neuropilin 1, medicine, NRP1, QKI5, Animals, Humans, Secretion, Cell Proliferation, Cell growth, Chemistry, Growth factor, Trophoblast, RNA-Binding Proteins, Cell Biology, Original Articles, trophoblast, Hedgehog signaling pathway, Neuropilin-1, Cell biology, Trophoblasts, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Receptors, Vascular Endothelial Growth Factor, Matrix Metalloproteinase 9, 030220 oncology & carcinogenesis, Case-Control Studies, Molecular Medicine, Original Article, Female, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4918015cab186bc5d21a6f1f0b02e93Test
http://europepmc.org/articles/PMC8184681Test

7

Methionine Commits Cells to Differentiate Into Plasmablasts Through Epigenetic Regulation ofBTBandCNCHomolog 2 by the MethyltransferaseEZH2

المؤلفون: Shingo Nakayamada, Masanobu Ueno, Tong Zhang, Mingzeng Zhang, Maiko Hajime, Naoaki Ohkubo, Shigeru Iwata, Hiroko Miyata, Jie Fan, Kaoru Yamagata, Yasuyuki Todoroki, He Hao, Yoshiya Tanaka

المصدر: Arthritis & Rheumatology. 72:1143-1153

مصطلحات موضوعية: Adult, Male, X-Box Binding Protein 1, 0301 basic medicine, Methyltransferase, Plasma Cells, Immunology, B-cell receptor, mTORC1, Mechanistic Target of Rapamycin Complex 1, CD19, Epigenesis, Genetic, 03 medical and health sciences, chemistry.chemical_compound, Methionine, 0302 clinical medicine, Rheumatology, Interferon, medicine, Humans, Lupus Erythematosus, Systemic, Syk Kinase, Immunology and Allergy, Enhancer of Zeste Homolog 2 Protein, Amino Acids, Cells, Cultured, B cell, Autoantibodies, chemistry.chemical_classification, biology, Precursor Cells, B-Lymphoid, Cell Differentiation, Middle Aged, Amino acid, Cell biology, Basic-Leucine Zipper Transcription Factors, 030104 developmental biology, medicine.anatomical_structure, Gene Expression Regulation, chemistry, Case-Control Studies, biology.protein, Female, Positive Regulatory Domain I-Binding Factor 1, 030215 immunology, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f83c76a30bddc46586697dcc78ae03Test
https://doi.org/10.1002/art.41208Test

8

The influence of fibroblast growth factor 2 on the senescence of human adipose-derived mesenchymal stem cells during long-term culture

المؤلفون: Nai-Chen Cheng, Kai-Hsuan Lin, Tai-Horng Young, Yin Cheng

المصدر: Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 9, Iss 4, Pp 518-530 (2020)

مصطلحات موضوعية: 0301 basic medicine, Carcinogenesis, animal diseases, Fibroblast growth factor, Cell morphology, Regenerative medicine, 0302 clinical medicine, Risk Factors, Tissue‐specific Progenitor and Stem Cells, cellular senescence, Phosphorylation, Extracellular Signal-Regulated MAP Kinases, STAT3, Cells, Cultured, mesenchymal stem cell, lcsh:R5-920, biology, lcsh:Cytology, Chemistry, Cell Differentiation, hemic and immune systems, General Medicine, Middle Aged, Up-Regulation, Cell biology, Female, Fibroblast Growth Factor 2, lcsh:Medicine (General), Adult, STAT3 Transcription Factor, endocrine system, animal structures, long‐term culture, Immunophenotyping, 03 medical and health sciences, Downregulation and upregulation, Humans, Receptor, Fibroblast Growth Factor, Type 1, lcsh:QH573-671, Cell Shape, Cell growth, Fibroblast growth factor receptor 1, Mesenchymal stem cell, Mesenchymal Stem Cells, Cell Biology, eye diseases, cell proliferation, 030104 developmental biology, biology.protein, 030217 neurology & neurosurgery, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd196a0ef75c256348809f3670b58643Test
https://doi.org/10.1002/sctm.19-0234Test

9

ABCA1- and ABCG1-mediated cholesterol efflux capacity of cerebrospinal fluid is impaired in Alzheimer's disease

المؤلفون: Franco Bernini, Maria Pia Adorni, Francesca Zimetti, Daniela Galimberti, Paolo Caffarra, Cinzia Marchi, Marco Spallazzi, Nicoletta Ronda, Federica Barocco

المصدر: Journal of Lipid Research, Vol 60, Iss 8, Pp 1449-1456 (2019)
J Lipid Res

مصطلحات موضوعية: 0301 basic medicine, Apolipoprotein E, Adult, Male, medicine.medical_specialty, apolipoprotein A-I, QD415-436, 030204 cardiovascular system & hematology, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Cerebrospinal fluid, Alzheimer Disease, Internal medicine, medicine, Dementia, Humans, ATP Binding Cassette Transporter, Subfamily G, Member 1, Aged, apolipoprotein E, ATP-binding cassette A1, Amyloid beta-Peptides, biology, Cholesterol, business.industry, Neurodegeneration, ATP-binding cassette G1, Cell Biology, Middle Aged, apolipoprotein E4, medicine.disease, Pathophysiology, Peptide Fragments, 030104 developmental biology, chemistry, ABCA1, biology.protein, cardiovascular system, Female, lipids (amino acids, peptides, and proteins), Efflux, business, Patient-Oriented and Epidemiological Research, apolipoproteins, ATP Binding Cassette Transporter 1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c32af647e6d95ae13ea957fc028bbe95Test
http://www.sciencedirect.com/science/article/pii/S0022227520322392Test

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Secreted modular calcium-binding protein 1 binds and activates thrombin to account for platelet hyperreactivity in diabetes

المؤلفون: Dagmar Meyer zu Heringdorf, Corina Ratiu, Amro Elgheznawy, Voahanginirina Randriamboavonjy, Anastasia Kyselova, Ingrid Fleming, Mauro Siragusa, Alexander W. Mann, Beate Fisslthaler, Fredy Delgado Lagos

المصدر: Blood. 137:1641-1651

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bcf0b32aeb935a44038d5325894fca8Test
https://doi.org/10.1182/blood.2020009405Test

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