نتائج البحث

1

Pembrolizumab Plus Ipilimumab Following Anti-PD-1/L1 Failure in Melanoma

المصدر: J Clin Oncol

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53f50387d5994f75ceeba750e8bc2f9Test
https://doi.org/10.1200/jco.21.00079Test

2

Lipase elevation and type 1 diabetes mellitus related to immune checkpoint inhibitor therapy – A multicentre study of 90 patients from the German Dermatooncology Group

المؤلفون: Michael Momma, Carmen Loquai, Cristel Ruini, Corinna Kochanek, Kai-Martin Thoms, Selma Ugurel, Carola Berking, Lisa Zimmer, Friedegund Meier, Katharina C. Kähler, Lucie Heinzerling, Dirk Debus, Jessica C. Hassel, Imke Grimmelmann, Claudia Pföhler, Jochen Utikal, Rudolf A. Herbst, Thomas Eigentler, Ralf Gutzmer

المصدر: European Journal of Cancer. 149:1-10

مصطلحات موضوعية: Adult, Blood Glucose, Male, 0301 basic medicine, Cancer Research, medicine.medical_specialty, Skin Neoplasms, Time Factors, Medizin, Gastroenterology, Thyroiditis, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Predictive Value of Tests, Germany, Internal medicine, Diabetes mellitus, medicine, Humans, Lipase, Adverse effect, Immune Checkpoint Inhibitors, Melanoma, Aged, Retrospective Studies, Aged, 80 and over, Type 1 diabetes, biology, business.industry, Diabetes, Immune checkpoint inhibitors, Immune-related adverse events, Ipilimumab, Nivolumab, Pancreatitis, PD-1 inhibitor, Pembrolizumab, Biomarkers, Diabetes Mellitus, Type 1, Exocrine Pancreatic Insufficiency, Female, Middle Aged, Treatment Outcome, Up-Regulation, medicine.disease, Ketoacidosis, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, biology.protein, Skin cancer, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46f4bea919fbf1345c4e5a2fd89e7ccTest
https://doi.org/10.1016/j.ejca.2021.02.017Test

3

Pancreatic Differentiation of Stem Cells Reveals Pathogenesis of a Syndrome of Ketosis-Prone Diabetes

المؤلفون: Nagireddy Putluri, Sanjeet Patel, James W. Suliburk, Jolanta Chmielowiec, Diane Yang, Arun Sreekumar, Malgorzata Borowiak, Wojciech J. Szlachcic, Michael L. Metzker, Diane I. Scaduto, Ashok Balasubramanyam

المصدر: Diabetes

مصطلحات موضوعية: Adult, Male, Endocrinology, Diabetes and Metabolism, DNA Mutational Analysis, Induced Pluripotent Stem Cells, 030209 endocrinology & metabolism, Enteroendocrine cell, Biology, 03 medical and health sciences, 0302 clinical medicine, Insulin-Secreting Cells, Internal Medicine, medicine, Transcriptional regulation, Humans, Induced pluripotent stem cell, Pancreas, Cells, Cultured, PI3K/AKT/mTOR pathway, 030304 developmental biology, Homeodomain Proteins, 0303 health sciences, Genetics/Genomes/Proteomics/Metabolomics, Cell Differentiation, Syndrome, medicine.disease, Diabetes Mellitus, Type 1, Gene Expression Regulation, Trans-Activators, Cancer research, PDX1, Stem cell, Ketosis-prone diabetes, Definitive endoderm

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524a243b490a4f59f169cb619acba9c4Test
https://doi.org/10.2337/figshare.15070170.v2Test

4

Efficacy of Decitabine plus Anti-PD-1 Camrelizumab in Patients with Hodgkin Lymphoma Who Progressed or Relapsed after PD-1 Blockade Monotherapy

المؤلفون: Miao Liu, Malcolm V. Brock, Qingming Yang, Fengxia Shi, Jing Nie, Liang Dong, Jiejie Liu, Weidong Han, Qian Mei, Chunmeng Wang, Yang Liu, Xiang Li, Meixia Chen

المصدر: Clinical Cancer Research. 27:2782-2791

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Cancer Research, medicine.medical_specialty, Adolescent, Programmed Cell Death 1 Receptor, Decitabine, Kaplan-Meier Estimate, Antibodies, Monoclonal, Humanized, Gastroenterology, B7-H1 Antigen, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Refractory, Recurrence, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, In patient, Child, Neoplasm Staging, business.industry, Anti pd 1, Middle Aged, Prognosis, Hodgkin Disease, Blockade, Treatment Outcome, 030104 developmental biology, Oncology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Retreatment, Cohort, Disease Progression, Pd 1 blockade, Hodgkin lymphoma, Female, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e09f7bc2baaa5514edccb162437f68Test
https://doi.org/10.1158/1078-0432.ccr-21-0133Test

5

Mechanistic insights into immune checkpoint inhibitor-related hypophysitis: a form of paraneoplastic syndrome

المؤلفون: Ryusaku Matsumoto, Masaaki Yamamoto, Genzo Iguchi, Shin Urai, Hidenori Fukuoka, Wataru Ogawa, Kentaro Suda, Hiroki Shichi, Keitaro Kanie, Yutaka Takahashi, Hironori Bando, Yasunori Fujita

المصدر: Cancer Immunology, Immunotherapy

مصطلحات موضوعية: Male, Cancer Research, Pro-Opiomelanocortin, Paraneoplastic Syndromes, Programmed Cell Death 1 Receptor, Autoimmunity, Hypopituitarism, Immune checkpoint inhibitor, medicine.disease_cause, B7-H1 Antigen, Mice, 0302 clinical medicine, Neoplasms, Immunology and Allergy, CTLA-4 Antigen, Corticotrophs, Immune Checkpoint Inhibitors, Aged, 80 and over, biology, Middle Aged, Oncology, 030220 oncology & carcinogenesis, Paraneoplastic syndrome, Female, Original Article, Immunotherapy, Antibody, hormones, hormone substitutes, and hormone antagonists, Adult, endocrine system, Hypophysitis, Immunology, 030209 endocrinology & metabolism, Adrenocorticotropic hormone, 03 medical and health sciences, Antigen, medicine, Animals, Humans, Aged, Retrospective Studies, business.industry, medicine.disease, biology.protein, Ectopic expression, Corticotropic cell, business, Adrenal Insufficiency

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3acc181a81511e7fe6b828ea748faa32Test
https://hdl.handle.net/20.500.14094/90008773Test

6

First‐line pembrolizumab vs chemotherapy in metastatic non‐small‐cell lung cancer: KEYNOTE‐024 Japan subset*

المصدر: Cancer Science
Cancer Sci

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Lung Neoplasms, medicine.medical_treatment, Programmed Cell Death 1 Receptor, non‐small‐cell lung carcinoma, Pembrolizumab, Kaplan-Meier Estimate, Gastroenterology, Deoxycytidine, B7-H1 Antigen, Carboplatin, 0302 clinical medicine, Antineoplastic Agents, Immunological, Japan, Carcinoma, Non-Small-Cell Lung, Antineoplastic Combined Chemotherapy Protocols, Anaplastic Lymphoma Kinase, Neoplasm Metastasis, Aged, 80 and over, Cross-Over Studies, Hazard ratio, General Medicine, Middle Aged, PD-L1 protein, Progression-Free Survival, Oncology, 030220 oncology & carcinogenesis, non-small-cell lung carcinoma, Carcinoma, Squamous Cell, Female, Original Article, Non small cell, pembrolizumab, Adult, medicine.medical_specialty, Paclitaxel, First line, Pemetrexed, Antibodies, Monoclonal, Humanized, Drug Administration Schedule, 03 medical and health sciences, Drug Therapy, Clinical Research, Internal medicine, medicine, Confidence Intervals, Humans, Lung cancer, Adverse effect, PD‐L1 protein, Aged, Chemotherapy, business.industry, Genes, erbB-1, Original Articles, medicine.disease, Survival Analysis, Gemcitabine, Confidence interval, Retraction, 030104 developmental biology, treatment outcome, Cisplatin, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4692f872031566a6ba7ec9528f7d1191Test
https://doi.org/10.1111/cas.15144Test

7

In vivo inducible reverse genetics in patients’ tumors to identify individual therapeutic targets

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications

مصطلحات موضوعية: Male, Oncogene Proteins, Fusion, medicine.medical_treatment, General Physics and Astronomy, Targeted therapy, Mice, 0302 clinical medicine, RNA interference, Leukaemia, MCL1, Precision Medicine, Child, 0303 health sciences, Acute leukemia, Multidisciplinary, Precursor Cell Lymphoblastic Leukemia-Lymphoma, ddc, 3. Good health, Leukemia, Myeloid, Acute, 030220 oncology & carcinogenesis, Female, Functional genomics, Myeloid-Lymphoid Leukemia Protein, Adult, Article, Cancer models, Genetic engineering, Science, Antineoplastic Agents, Biology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, In vivo, medicine, Biomarkers, Tumor, Gene silencing, Animals, Humans, ddc:610, Gene Silencing, 030304 developmental biology, Adaptor Proteins, Signal Transducing, Homeodomain Proteins, General Chemistry, Xenograft Model Antitumor Assays, Reverse genetics, Reverse Genetics, Cancer research, Myeloid Cell Leukemia Sequence 1 Protein

وصف الملف: application/octet-stream; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c108a41db88aecd0352ded6d797fe0aTest
https://doaj.org/article/6e797a213a574904a9cff02ded829844Test

8

HIF-1α inhibits mitochondria-mediated apoptosis and improves the survival of human adipose-derived stem cells in ischemic microenvironments

المؤلفون: Hao Wu, Tianqi Lv, Jiayi Xu, Giorgi Oganezov, Hao Pang, Jie Wang, Xiaoqun Dong, Ying Liu, Jiaxu Li, Yongting Zhou, Zhibo Xiao

المصدر: Journal of Plastic, Reconstructive & Aesthetic Surgery. 74:1908-1918

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e573a53bb25a6eabb01b7e66f94501Test
https://doi.org/10.1016/j.bjps.2020.11.041Test

9

FAM13A as potential therapeutic target in modulating TGF-β-induced airway tissue remodeling in COPD

المؤلفون: Ling Vicky Li, Dominik Witzigmann, Gurpreet K. Singhera, Chen X. Yang, Tillie-Louise Hackett, James C. Hogg, Pascal Leclair, Jayesh A. Kulkarni, Pieter R. Cullis, Xuan Li, Delbert R. Dorscheid, Don D. Sin, Chinten James Lim, Anthony Tam

المصدر: American Journal of Physiology-Lung Cellular and Molecular Physiology. 321:L377-L391

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Pulmonary and Respiratory Medicine, MMP2, Physiology, Respiratory Mucosa, Matrix metalloproteinase, Collagen Type I, Cell Line, Transforming Growth Factor beta1, Pulmonary Disease, Chronic Obstructive, 03 medical and health sciences, 0302 clinical medicine, Physiology (medical), medicine, Humans, Respiratory system, Gene, beta Catenin, Aged, COPD, business.industry, GTPase-Activating Proteins, Smoking, Cell Biology, Middle Aged, medicine.disease, respiratory tract diseases, Collagen Type I, alpha 1 Chain, 030104 developmental biology, Gene Expression Regulation, 030228 respiratory system, Cancer research, Airway Remodeling, Matrix Metalloproteinase 2, Respiratory epithelium, Female, Airway, business, Transforming growth factor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2260812509351341d8be551a444a1234Test
https://doi.org/10.1152/ajplung.00477.2020Test

10

The Dynamic Alternation of Local and Systemic Tumor Immune Microenvironment During Concurrent Chemoradiotherapy of Cervical Cancer: A Prospective Clinical Trial

المؤلفون: Rui Li, Limei Yin, Sun Chuntang, Kemin Li, Jianxin Xue, Ruizhan Tong, Rutie Yin, Zhipeng Zhou, Y. Liu, You Lu, Pansong Li

المصدر: International Journal of Radiation Oncology*Biology*Physics. 110:1432-1441

مصطلحات موضوعية: Adult, CD4-Positive T-Lymphocytes, Oncology, Radiation-Sensitizing Agents, Cancer Research, medicine.medical_specialty, Time Factors, Brachytherapy, Programmed Cell Death 1 Receptor, Uterine Cervical Neoplasms, CD8-Positive T-Lymphocytes, Peripheral blood mononuclear cell, B7-H1 Antigen, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Confidence Intervals, Tumor Microenvironment, medicine, Humans, Radiology, Nuclear Medicine and imaging, Prospective Studies, Progression-free survival, Prospective cohort study, Aged, Cisplatin, Cervical cancer, Radiation, business.industry, T-cell receptor, Radiotherapy Dosage, Chemoradiotherapy, Middle Aged, medicine.disease, Progression-Free Survival, 030220 oncology & carcinogenesis, Leukocytes, Mononuclear, Female, business, CD8, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898ac1fc1e825c6325cc7ee598e51e60Test
https://doi.org/10.1016/j.ijrobp.2021.03.003Test

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