نتائج البحث

1

MiR-27a-3p/miR-27b-3p Promotes Neurofibromatosis Type 1 via Targeting of NF1

المؤلفون: Quantang Pang, Ping Liu, Lu Hongyu

المصدر: Journal of Molecular Neuroscience. 71:2353-2363

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ebafec1d63aca1c7ef5f4082c4944eTest
https://doi.org/10.1007/s12031-020-01779-2Test

2

Expression of immunoreactive inducible nitric oxide synthase in pancreatic islet cells from newly diagnosed and long-term type 1 diabetic donors is heterogeneous and not disease-associated

المؤلفون: Knut Dahl-Jørgensen, Shiva Reddy, Lars Krogvold, Owen Martin, Charlton Martin, Kevin Xueying Sun, Aamenah Al-Ani

المصدر: Cell and Tissue Research. 384:655-674

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, endocrine system, medicine.medical_specialty, Histology, Adolescent, endocrine system diseases, Nitric Oxide Synthase Type II, Nitric Oxide, Glucagon, Pathology and Forensic Medicine, Proinflammatory cytokine, Nitric oxide, Islets of Langerhans, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, medicine, Humans, Beta (finance), Cells, Cultured, Type 1 diabetes, geography, geography.geographical_feature_category, biology, Chemistry, Cell Biology, medicine.disease, Islet, Nitric oxide synthase, Diabetes Mellitus, Type 1, 030104 developmental biology, Endocrinology, biology.protein, Female, Beta cell, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6728a9832de8ac370bf9e4176fa86c25Test
https://doi.org/10.1007/s00441-020-03340-4Test

3

TRIM21 drives intervertebral disc degeneration induced by oxidative stress via mediating HIF-1α degradation

المؤلفون: Changwei Li, Jiancheng Zheng, Leilei Chang, Xingkai Zhang, Lianfu Deng, Xiaogang Bao

المصدر: Biochemical and Biophysical Research Communications. 555:46-53

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Nucleus Pulposus, Adolescent, Biophysics, Intervertebral Disc Degeneration, Degeneration (medical), Oxidative phosphorylation, medicine.disease_cause, Biochemistry, Rats, Sprague-Dawley, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Ubiquitin, Downregulation and upregulation, medicine, Animals, Humans, Molecular Biology, Cells, Cultured, Aged, biology, Chemistry, Intervertebral disc, Hydrogen Peroxide, Cell Biology, Middle Aged, Hypoxia-Inducible Factor 1, alpha Subunit, Ubiquitin ligase, Cell biology, Oxidative Stress, 030104 developmental biology, medicine.anatomical_structure, Ribonucleoproteins, 030220 oncology & carcinogenesis, Disc degeneration, biology.protein, Female, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1f9723c47a8babbaba448cb61e293abTest
https://doi.org/10.1016/j.bbrc.2021.03.088Test

4

Methionine Commits Cells to Differentiate Into Plasmablasts Through Epigenetic Regulation ofBTBandCNCHomolog 2 by the MethyltransferaseEZH2

المؤلفون: Shingo Nakayamada, Masanobu Ueno, Tong Zhang, Mingzeng Zhang, Maiko Hajime, Naoaki Ohkubo, Shigeru Iwata, Hiroko Miyata, Jie Fan, Kaoru Yamagata, Yasuyuki Todoroki, He Hao, Yoshiya Tanaka

المصدر: Arthritis & Rheumatology. 72:1143-1153

مصطلحات موضوعية: Adult, Male, X-Box Binding Protein 1, 0301 basic medicine, Methyltransferase, Plasma Cells, Immunology, B-cell receptor, mTORC1, Mechanistic Target of Rapamycin Complex 1, CD19, Epigenesis, Genetic, 03 medical and health sciences, chemistry.chemical_compound, Methionine, 0302 clinical medicine, Rheumatology, Interferon, medicine, Humans, Lupus Erythematosus, Systemic, Syk Kinase, Immunology and Allergy, Enhancer of Zeste Homolog 2 Protein, Amino Acids, Cells, Cultured, B cell, Autoantibodies, chemistry.chemical_classification, biology, Precursor Cells, B-Lymphoid, Cell Differentiation, Middle Aged, Amino acid, Cell biology, Basic-Leucine Zipper Transcription Factors, 030104 developmental biology, medicine.anatomical_structure, Gene Expression Regulation, chemistry, Case-Control Studies, biology.protein, Female, Positive Regulatory Domain I-Binding Factor 1, 030215 immunology, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f83c76a30bddc46586697dcc78ae03Test
https://doi.org/10.1002/art.41208Test

5

The influence of fibroblast growth factor 2 on the senescence of human adipose-derived mesenchymal stem cells during long-term culture

المؤلفون: Nai-Chen Cheng, Kai-Hsuan Lin, Tai-Horng Young, Yin Cheng

المصدر: Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 9, Iss 4, Pp 518-530 (2020)

مصطلحات موضوعية: 0301 basic medicine, Carcinogenesis, animal diseases, Fibroblast growth factor, Cell morphology, Regenerative medicine, 0302 clinical medicine, Risk Factors, Tissue‐specific Progenitor and Stem Cells, cellular senescence, Phosphorylation, Extracellular Signal-Regulated MAP Kinases, STAT3, Cells, Cultured, mesenchymal stem cell, lcsh:R5-920, biology, lcsh:Cytology, Chemistry, Cell Differentiation, hemic and immune systems, General Medicine, Middle Aged, Up-Regulation, Cell biology, Female, Fibroblast Growth Factor 2, lcsh:Medicine (General), Adult, STAT3 Transcription Factor, endocrine system, animal structures, long‐term culture, Immunophenotyping, 03 medical and health sciences, Downregulation and upregulation, Humans, Receptor, Fibroblast Growth Factor, Type 1, lcsh:QH573-671, Cell Shape, Cell growth, Fibroblast growth factor receptor 1, Mesenchymal stem cell, Mesenchymal Stem Cells, Cell Biology, eye diseases, cell proliferation, 030104 developmental biology, biology.protein, 030217 neurology & neurosurgery, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd196a0ef75c256348809f3670b58643Test
https://doi.org/10.1002/sctm.19-0234Test

6

ABCA1- and ABCG1-mediated cholesterol efflux capacity of cerebrospinal fluid is impaired in Alzheimer's disease

المؤلفون: Franco Bernini, Maria Pia Adorni, Francesca Zimetti, Daniela Galimberti, Paolo Caffarra, Cinzia Marchi, Marco Spallazzi, Nicoletta Ronda, Federica Barocco

المصدر: Journal of Lipid Research, Vol 60, Iss 8, Pp 1449-1456 (2019)
J Lipid Res

مصطلحات موضوعية: 0301 basic medicine, Apolipoprotein E, Adult, Male, medicine.medical_specialty, apolipoprotein A-I, QD415-436, 030204 cardiovascular system & hematology, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Cerebrospinal fluid, Alzheimer Disease, Internal medicine, medicine, Dementia, Humans, ATP Binding Cassette Transporter, Subfamily G, Member 1, Aged, apolipoprotein E, ATP-binding cassette A1, Amyloid beta-Peptides, biology, Cholesterol, business.industry, Neurodegeneration, ATP-binding cassette G1, Cell Biology, Middle Aged, apolipoprotein E4, medicine.disease, Pathophysiology, Peptide Fragments, 030104 developmental biology, chemistry, ABCA1, biology.protein, cardiovascular system, Female, lipids (amino acids, peptides, and proteins), Efflux, business, Patient-Oriented and Epidemiological Research, apolipoproteins, ATP Binding Cassette Transporter 1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c32af647e6d95ae13ea957fc028bbe95Test
http://www.sciencedirect.com/science/article/pii/S0022227520322392Test

7

Secreted modular calcium-binding protein 1 binds and activates thrombin to account for platelet hyperreactivity in diabetes

المؤلفون: Dagmar Meyer zu Heringdorf, Corina Ratiu, Amro Elgheznawy, Voahanginirina Randriamboavonjy, Anastasia Kyselova, Ingrid Fleming, Mauro Siragusa, Alexander W. Mann, Beate Fisslthaler, Fredy Delgado Lagos

المصدر: Blood. 137:1641-1651

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bcf0b32aeb935a44038d5325894fca8Test
https://doi.org/10.1182/blood.2020009405Test

8

Activation of angiotensin type 2 receptor attenuates testosterone-induced hypertension and uterine vascular resistance in pregnant rats

المؤلفون: Sathish Kumar, Jay S. Mishra

المصدر: Biol Reprod

مصطلحات موضوعية: Adult, 0301 basic medicine, Gestational hypertension, medicine.medical_specialty, Nitric Oxide Synthase Type III, Endothelium, Bradykinin, Vasodilation, 030204 cardiovascular system & hematology, Biology, Receptor, Angiotensin, Type 2, Receptor, Angiotensin, Type 1, Preeclampsia, Rats, Sprague-Dawley, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Enos, Internal medicine, medicine, Animals, Humans, Testosterone, Uterus, Cell Biology, General Medicine, medicine.disease, biology.organism_classification, Angiotensin II, Rats, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Reproductive Medicine, chemistry, Hypertension, Vascular resistance, Female, Vascular Resistance, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8311c4622599810c922ef90122b202d3Test
https://doi.org/10.1093/biolre/ioab051Test

9

Intracellular immune sensing promotes inflammation via gasdermin D–driven release of a lectin alarmin

المصدر: Nat Immunol

مصطلحات موضوعية: Lipopolysaccharides, Male, 0301 basic medicine, Galectin 1, Lipopolysaccharide, Mice, chemistry.chemical_compound, 0302 clinical medicine, Alarmins, Immunology and Allergy, Caspase, Aged, 80 and over, Mice, Knockout, biology, Intracellular Signaling Peptides and Proteins, Pyroptosis, Middle Aged, Up-Regulation, Cell biology, Necroptosis, Female, Inflammation Mediators, medicine.symptom, Signal transduction, Intracellular, Signal Transduction, Adult, animal structures, Immunology, Inflammation, PTPRC, Article, 03 medical and health sciences, Sepsis, otorhinolaryngologic diseases, medicine, Animals, Humans, Aged, Macrophages, Phosphate-Binding Proteins, Endotoxemia, Mice, Inbred C57BL, Disease Models, Animal, stomatognathic diseases, RAW 264.7 Cells, 030104 developmental biology, chemistry, Case-Control Studies, biology.protein, Leukocyte Common Antigens, HeLa Cells, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcd368de112bdf46f79b07a7aa7e0a0dTest
https://doi.org/10.1038/s41590-020-00844-7Test

10

snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis

المؤلفون: Aviv Regev, Eugene Drokhlyansky, Jozef Ukropec, Christian Wolfrum, Lucia Balazova, Gottfried Rudofsky, Wenfei Sun, Antonio Giordano, Lianggong Ding, Miroslav Balaz, Anna Sofie Husted, Patrik Stefanicka, Georgia Colleluori, Michal Slyper, Saverio Cinti, Zuzana Kovanicova, Thue W. Schwartz, Hua Dong

المصدر: Cell Metab

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d0e829fb1d588b5e9be24e980e95e0Test
https://doi.org/10.1038/s41586-020-2856-xTest

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