المؤلفون: Diana Babaevskaya, Andrey Proshin, Igor Pomytkin, Margarita Oplatchikova, Tatyana Strekalova, Johannes P.J.M. de Munter, D. A. Pavlov, Allan V. Kalueff, Klaus-Peter Lesch, Ekaterina Lysikova, Anna Gorlova, Erik Ch. Wolters, Aleksei Umriukhin

المساهمون: Psychiatrie & Neuropsychologie, RS: MHeNs - R3 - Neuroscience

المصدر: Journal of Cellular and Molecular Medicine, 24(17), 10251-10257. Wiley-Blackwell
Journal of Cellular and Molecular Medicine
J. Cell. Mol. Med.

مصطلحات موضوعية: Male, Pathology, amyotrophic lateral sclerosis, PROTEIN EXPRESSION, EXPERIMENTAL NEUROINFLAMMATION, REAL TIME POLYMERASE CHAIN REACTION, MOUSE, ANIMAL EXPERIMENT, stem cell therapy, FUS[1‐359]‐tg mice, Mice, 0302 clinical medicine, SUCROSE PREFERENCE TEST, CELECOXIB, BRAIN, MUTATION, FUS[1-359]-tg mice, Neurons, RNA BINDING PROTEIN FUS, Behavior, Animal, celecoxib, LOCOMOTION, Neurodegeneration, TRANSGENIC MOUSE, Brain, DEPRESSION, Riluzole, Spinal Cord, 030220 oncology & carcinogenesis, RNA ISOLATION, CALCIUM BINDING PROTEIN, DRUG EFFECT, medicine.medical_specialty, Short Communication, Short Communications, FUS PROTEIN, MOUSE, IONIZED CALCIUM BINDING ADAPTOR MOLECULE 1, BEHAVIOR, ANIMAL, INTERLEUKIN-1BETA, NEUROINFLAMMATION, 03 medical and health sciences, TAIL SUSPENSION TEST, NONHUMAN, Social Behavior, ELEVATED PLUS MAZE TEST, INTERLEUKIN 1BETA, FRONTOTEMPORAL LOBAR DEGENERATION, Glycogen Synthase Kinase 3 beta, animal model, ANIMALS, ANIMAL, medicine.disease, FUS[1-359]-TG MICE, Molecular medicine, 030104 developmental biology, Mutation, HIPPOCAMPUS, emotionality and cognition, CYCLOOXYGENASE 1, HOME-CAGE ACTIVITY TEST, ABNORMAL BEHAVIOR, SPINAL CORD, GELATINASE B, CYCLOOXYGENASE 2, 0301 basic medicine, MATRIX METALLOPROTEINASES, NERVE CELL, Interleukin-1beta, Anti-Inflammatory Agents, Hippocampus, PREFRONTAL CORTEX, ANIMAL MODEL, UNCLASSIFIED DRUG, neuroinflammation, MARBLE BURYING TEST, ANXIETY, COGNITIVE DEFECT, TISSUE INHIBITOR OF METALLOPROTEINASE 1, PLASTICITY, Amyotrophic lateral sclerosis, NEURONS, MOLECULAR MARKER, Frontotemporal lobar degeneration, STEM CELL, riluzole, Muscle atrophy, GENOTYPE, ANTIINFLAMMATORY ACTIVITY, frontotemporal lobar degeneration, BIOLOGICAL MARKER, GLYCOGEN SYNTHASE KINASE 3BETA, Molecular Medicine, AMYOTROPHIC LATERAL SCLEROSIS, RNA-BINDING PROTEIN FUS, medicine.symptom, ANTIINFLAMMATORY AGENT, medicine.drug, STEM CELL THERAPY, GLYCOGEN SYNTHASE KINASE 3 BETA, CAGE TEST, METABOLISM, ADULT, INFLAMMATION, WESTERN BLOTTING, ANIMAL TISSUE, GENE MUTATION, OPEN FIELD TEST, EMOTION, medicine, Animals, RESIDENT-INTRUDER TEST, ARTICLE, NERVE DEGENERATION, Neuroinflammation, Inflammation, MALE, TUMOR NECROSIS FACTOR, INTRACEREBROVENTRICULAR DRUG ADMINISTRATION, business.industry, SOCIAL BEHAVIOR, ANTI-INFLAMMATORY AGENTS, Cell Biology, FRONTOTEMPORAL DEMENTIA, ANIMAL BEHAVIOR, EMOTIONALITY AND COGNITION, CONTROLLED STUDY, MICE, GLYCOGEN SYNTHASE KINASE 3ALPHA, Cyclooxygenase 2, RILUZOLE, COGNITION, RNA-Binding Protein FUS, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e06827f1ecd2f754817e6fe6568533e8Test
https://cris.maastrichtuniversity.nl/en/publications/0162d1c6-abc0-4610-83d0-566d46a45289Test

المؤلفون: Taleen A. MacArthur, Aodhnait S. Fahy, James W. Jakub

المصدر: Am Surg

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Skin Neoplasms, Minnesota, Herpesvirus 1, Human, Injections, Intralesional, Article, 030207 dermatology & venereal diseases, 03 medical and health sciences, Antineoplastic Agents, Immunological, 0302 clinical medicine, Fluorodeoxyglucose F18, Surgical oncology, medicine, Humans, Melanoma, Pathological, Aged, Retrospective Studies, Ultrasonography, Fluorodeoxyglucose, Biological Products, medicine.diagnostic_test, business.industry, General Medicine, Middle Aged, medicine.disease, Institutional review board, Combined Modality Therapy, Oncolytic virus, Positron emission tomography, Positron-Emission Tomography, 030220 oncology & carcinogenesis, Radiology, Radiopharmaceuticals, business, Talimogene laherparepvec, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebd00bea70abd7699ee5efae05f43832Test
https://doi.org/10.1177/00031348211023434Test

المؤلفون: J. S. Haw, Michael Mauer, Janet B. McGill, Jill P. Crandall, Bruce A. Perkins, Ruth S. Weinstock, Katherine R. Tuttle, Afshin Parsa, Tom Elliott, Peter Rossing, Amy B. Karger, Amisha Wallia, Cathie Spino, Mark E. Molitch, I. H. de Boer, Maryam Afkarian, David Z.I. Cherney, Sylvia E. Rosas, Irl B. Hirsch, Sarit Polsky, Allison B. Goldfine, Andrzej T. Galecki, Guillermo E. Umpierrez, Ronald J. Sigal, Marlon Pragnell, Ildiko Lingvay, M. L. Caramori, Rodica Pop-Busui, Ronnie Aronson, William N. Robiner, Chun Yi Wu, David M. Maahs, Peter A. Senior, Alessandro Doria

المصدر: N Engl J Med

مصطلحات موضوعية: Adult, Male, Xanthine Oxidase, medicine.medical_specialty, Allopurinol, Urology, Renal function, 030204 cardiovascular system & hematology, Placebo, Article, Renin-Angiotensin System, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Double-Blind Method, Diabetes mellitus, medicine, Humans, Diabetic Nephropathies, Treatment Failure, 030212 general & internal medicine, Enzyme Inhibitors, Aged, Type 1 diabetes, business.industry, General Medicine, Middle Aged, medicine.disease, Uric Acid, Diabetes Mellitus, Type 1, chemistry, Uric acid, Female, Glycated hemoglobin, Iohexol, business, Glomerular Filtration Rate, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab6ef2b59ae2513d4a7415a3b5af846cTest
https://doi.org/10.1056/nejmoa1916624Test

المؤلفون: Kayla J. Wolf, Jonathan Rick, Alan T. Nguyen, Sumedh S. Shah, Harsh Wadhwa, Joseph H Garcia, Sören Müller, Luke A. Gilbert, Garima Yagnik, Sanjay Kumar, Manish K. Aghi, Matheus P. Pereira, Rushikesh S. Joshi, Jung-Ming G. Lin, Jacob Weiss, Aaron Diaz, Saket Jain, William S. Chen, Arman Jahangiri, Ankush Chandra

المصدر: Cancer research, vol 80, iss 7
Cancer Res

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Drug Resistance, Angiogenesis Inhibitors, 0302 clinical medicine, Stem Cell Research - Nonembryonic - Human, Phytogenic, Antineoplastic Combined Chemotherapy Protocols, Tumor Microenvironment, 2.1 Biological and endogenous factors, Medicine, Aetiology, Cancer, Tumor, Neovascularization, Pathologic, Brain Neoplasms, Brain, Middle Aged, Phenotype, Cell Hypoxia, Up-Regulation, Gene Expression Regulation, Neoplastic, Bevacizumab, Oncology, 5.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Neoplastic Stem Cells, Female, Development of treatments and therapeutic interventions, Stem cell, medicine.symptom, Biotechnology, medicine.drug, Adult, Programmed cell death, Epithelial-Mesenchymal Transition, Oncology and Carcinogenesis, Antineoplastic Agents, Article, Lignans, Cell Line, Young Adult, 03 medical and health sciences, Rare Diseases, Downregulation and upregulation, Cell Line, Tumor, Human Umbilical Vein Endothelial Cells, Animals, Humans, Neoplasm Invasiveness, Chitinase-3-Like Protein 1, Oncology & Carcinogenesis, Neovascularization, Aged, Pathologic, Neoplastic, business.industry, Microarray analysis techniques, Biphenyl Compounds, Mesenchymal stem cell, Zinc Finger E-box-Binding Homeobox 1, Hypoxia (medical), Stem Cell Research, Antineoplastic Agents, Phytogenic, Xenograft Model Antitumor Assays, Brain Disorders, Brain Cancer, 030104 developmental biology, Gene Expression Regulation, Drug Resistance, Neoplasm, Cancer research, Neoplasm, sense organs, Glioblastoma, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31078c3c37cef95ce34f6641ccd4652aTest
https://doi.org/10.1158/0008-5472.can-19-1305Test

المؤلفون: Kevan C, Herold, Brian N, Bundy, S Alice, Long, Jeffrey A, Bluestone, Linda A, DiMeglio, Matthew J, Dufort, Stephen E, Gitelman, Peter A, Gottlieb, Jeffrey P, Krischer, Peter S, Linsley, Jennifer B, Marks, Wayne, Moore, Antoinette, Moran, Henry, Rodriguez, William E, Russell, Desmond, Schatz, Jay S, Skyler, Eva, Tsalikian, Diane K, Wherrett, Anette-Gabriele, Ziegler, Carla J, Greenbaum, Stuart, Weinzimer

المصدر: The New England journal of medicine, vol 381, iss 7

مصطلحات موضوعية: Male, CD3 Complex, T-Lymphocytes, 030204 cardiovascular system & hematology, Medical and Health Sciences, HLA-DR3 Antigen, 0302 clinical medicine, Monoclonal, Medicine, 030212 general & internal medicine, Child, Humanized, Glucose tolerance test, biology, Teplizumab, medicine.diagnostic_test, Anti-CD3 Antibody, Diabetes, General Medicine, Middle Aged, 6.1 Pharmaceuticals, Disease Progression, Female, Antibody, Type 1, medicine.drug, Adult, Adolescent, Clinical Trials and Supportive Activities, Metabolic and Endocrine, Antibodies, Monoclonal, Humanized, Autoimmune Disease, Antibodies, Article, Young Adult, 03 medical and health sciences, Double-Blind Method, Clinical Research, General & Internal Medicine, Lymphopenia, Diabetes mellitus, Diabetes Mellitus, HLA-DR4 Antigen, Humans, Lymphocyte Count, Proportional Hazards Models, Autoimmune disease, Type 1 diabetes, business.industry, Prevention, Type 1 Diabetes TrialNet Study Group, Exanthema, Glucose Tolerance Test, medicine.disease, Diabetes Mellitus, Type 1, Immunology, biology.protein, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e74cac9934865ec3bde41d3e5f7293Test
https://doi.org/10.1056/nejmoa1902226Test

المؤلفون: Sapna Pradyuman Patel, David S. Hong, Vivek Subbiah, Amanda Johnston, Siqing Fu, John S. Bomalaski, Sarina Anne Piha-Paul, Shuyang Yao, Ahmed Kaseb, Aung Naing, Nai Shi, Filip Janku, Apostolia Maria Tsimberidou, Shannon N. Westin, John Stewart

المصدر: Br J Cancer

مصطلحات موضوعية: Adult, Male, Cancer Research, Arginine, Hydrolases, Pharmacology, Article, Polyethylene Glycols, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, In vivo, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, Citrulline, Humans, Medicine, Melanoma, Arginine deiminase, Aged, Aged, 80 and over, Salvage Therapy, Cisplatin, business.industry, Middle Aged, Prognosis, Survival Rate, Argininosuccinate Synthetase 1, Oncology, chemistry, Tolerability, 030220 oncology & carcinogenesis, Toxicity, Female, business, Follow-Up Studies, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d35421e6155a20aeb943eeead2c5143Test
https://doi.org/10.1038/s41416-020-01230-8Test

المؤلفون: Margarita Gerou, Benjamin A. Hall, Scott P. Allen, Kathrin Meyer, Pamela J. Shaw, Ryan Woof, Jessica Allsop, Stephen J. Kolb

المصدر: Neurobiology of Aging

مصطلحات موضوعية: 0301 basic medicine, Male, Aging, AGEs, advanced glycation end products, SOD1, superoxide dismutase 1, DHAP, dihydroxyacetone phosphate, chemistry.chemical_compound, 0302 clinical medicine, FALS, familial amyotrophic lateral sclerosis, PGM, phosphoglucomutase, Glycolysis, Amyotrophic lateral sclerosis, SALS, sporadic amyotrophic lateral sclerosis, Glycogen, General Neuroscience, Middle Aged, ALS, amyotrophic lateral sclerosis, Aging, ALS, iNPC, induced neuronal progenitor cell, Disease Progression, Ketoglutaric Acids, Female, medicine.drug, Adult, medicine.medical_specialty, C9ORF72, chromosome 9 open reading frame 72, ETC, electron transport chain, Citric Acid Cycle, TCA, tricarboxylic acid, Context (language use), Biology, Article, 03 medical and health sciences, iPSC, induced pluripotent stem cells, ROS, reactive oxygen species, Internal medicine, medicine, Humans, LDHA, lactate dehydrogenase A, Progenitor cell, Inosine, Aged, G3P, glyceraldehyde 3-phosphate, GP, glycogen phosphorylase, NADH, nicotinamide adenine dinucleotide, reduced form, Amyotrophic Lateral Sclerosis, ChREBP, carbohydrate response element binding protein, Metabolism, Fibroblasts, iAstrocytes, induced astrocytes, medicine.disease, NAD, mtDNA, mitochondrial DNA, AMPK, AMP-activated protein kinase, 030104 developmental biology, Endocrinology, chemistry, Neurology (clinical), Geriatrics and Gerontology, Age of onset, TDP-43, TAR DNA-binding protein 43, Energy Metabolism, 030217 neurology & neurosurgery, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa322bad33369b41380c3947538e1343Test
http://europepmc.org/articles/PMC8346650Test

المؤلفون: Yan Gao, Jun Cai, Yi Xia, Qingqing Cai, Shuyun Ma, Yuchen Zhang, Lirong Li, Xiaopeng Tian, Hang Yang, Panpan Liu, Yajun Li, Xuanye Zhang, Hui Zhou, Huiqiang Huang

المصدر: Signal Transduction and Targeted Therapy, Vol 5, Iss 1, Pp 1-9 (2020)
Signal Transduction and Targeted Therapy

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Antibodies, Neoplasm, Programmed Cell Death 1 Receptor, lcsh:Medicine, Gastroenterology, Deoxycytidine, Polyethylene Glycols, 0302 clinical medicine, Antineoplastic Combined Chemotherapy Protocols, T-cell lymphoma, lcsh:QH301-705.5, Middle Aged, Neoplasm Proteins, Lymphoma, Extranodal NK-T-Cell, Oxaliplatin, Survival Rate, 030220 oncology & carcinogenesis, Female, medicine.drug, Adult, medicine.medical_specialty, Drug development, GemOx, Neutropenia, Predictive markers, Article, Disease-Free Survival, 03 medical and health sciences, Fluorodeoxyglucose F18, Internal medicine, Genetics, medicine, Asparaginase, Humans, Survival rate, Aged, Pegaspargase, Haematological cancer, business.industry, lcsh:R, medicine.disease, Gemcitabine, Regimen, 030104 developmental biology, lcsh:Biology (General), Positron-Emission Tomography, business, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6aa20c22427d24bef448ec18145aa9bTest
https://doaj.orgTest/article/99ff2da0b38046018a5c7ce878c81a7f

المؤلفون: Sun H. Kim, Bhanu Kalra, Gopal Savjani, Clara Nachmanoff, Fahim Abbasi, Christos S. Mantzoros, Konstantinos Stefanakis, Ajay Kumar

المصدر: Diabetes Obes Metab

مصطلحات موضوعية: Adult, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, 030209 endocrinology & metabolism, 030204 cardiovascular system & hematology, Proglucagon, Glucagon, Glucagon-Like Peptide-1 Receptor, Article, Alpha cell, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Insulin resistance, Glucagon-Like Peptide 1, Weight loss, Internal medicine, Insulin Secretion, Internal Medicine, medicine, Humans, Insulin, business.industry, Liraglutide, Body Weight, medicine.disease, Glucagon-like peptide-1, medicine.symptom, Peptides, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cbc0fe7aa521383986adcc483cf14c1Test
https://doi.org/10.1111/dom.14242Test

المؤلفون: Niya Liu, Lei Zhao, Stephanie Roessler, Fubo Ji, Xin Zheng, Zhao Ma, Junfang Ji, Xiyang Wei, Shuting Xue, Jianjuan Zhang, Ruizhe Ren, Jiong Shi, Xing Guo, Zhaogang Liu, Xin Wei Wang, Linda Wong

المصدر: Hepatology

مصطلحات موضوعية: Male, 0301 basic medicine, Cohort Studies, Gene Knockout Techniques, Mice, 0302 clinical medicine, Aged, 80 and over, education.field_of_study, CD24, Liver Neoplasms, Middle Aged, Hepatocellular carcinoma, Neoplastic Stem Cells, Female, 030211 gastroenterology & hepatology, Liver cancer, Signal Transduction, medicine.drug, Adult, Carcinoma, Hepatocellular, Adolescent, Population, Transfection, Article, Young Adult, 03 medical and health sciences, Cancer stem cell, microRNA, Biomarkers, Tumor, medicine, Animals, Humans, Chemoembolization, Therapeutic, education, Aged, Hepatology, business.industry, Hypoxia-Inducible Factor 1, alpha Subunit, medicine.disease, digestive system diseases, MicroRNAs, HEK293 Cells, 030104 developmental biology, HIF1A, A549 Cells, Drug Resistance, Neoplasm, Erythropoietin, Cancer research, Transcriptome, business, Proto-Oncogene Proteins c-akt

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce8941f479b6e08e1b61631b60f15ceTest
https://doi.org/10.1002/hep.31448Test