نتائج البحث

1

Peripheral immune circadian variation, synchronisation and possible dysrhythmia in established type 1 diabetes

المؤلفون: Carmella Evans-Molina, Clive Wasserfall, Megan T Legge, Eleni Beli, Craig A. Beam, Ryan Silk, Kieran M. Mcgrail, Linda A. DiMeglio, Mark A. Atkinson, Stephanie Woerner, Maria B. Grant

المصدر: Diabetologia
Beam, C A, Beli, E, Wasserfall, C H, Woerner, S E, Legge, M T, Evans-Molina, C, McGrail, K M, Silk, R, Grant, M B, Atkinson, M A & DiMeglio, L A 2021, ' Peripheral immune circadian variation, synchronisation and possible dysrhythmia in established type 1 diabetes ', Diabetologia . https://doi.org/10.1007/s00125-021-05468-6Test

مصطلحات موضوعية: 0301 basic medicine, CD4-Positive T-Lymphocytes, Male, type 1 diabetes, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Circadian clock, CD8-Positive T-Lymphocytes, T-Lymphocytes, Regulatory, Mice, 0302 clinical medicine, Cytotoxic T cell, education.field_of_study, B-Lymphocytes, Immune cells, Flow Cytometry, Circadian Rhythm, Cytokine, Type 1 diabetes, Female, Adult, Adolescent, Period (gene), Population, Biology, Chronobiology Disorders, circadian ryhtms, Article, 03 medical and health sciences, Clinical, Young Adult, Immune system, SDG 3 - Good Health and Well-being, Circadian Clocks, Internal Medicine, medicine, Animals, Humans, Circadian rhythms, Circadian rhythm, Lymphocyte Count, education, Interleukin-6, Dendritic Cells, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, Diabetes Mellitus, Type 1, Immune System, Immunology, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5304384a2a7eb86434e13bd1acc63ddbTest
http://europepmc.org/articles/PMC8245361Test

2

Beta cell-specific CD8+ T cells maintain stem-cell memory-associated epigenetic programs during type 1 diabetes

المصدر: Nature immunology
Nature immunology, vol 21, iss 5
Nature Immunology

مصطلحات موضوعية: 0301 basic medicine, Male, Cell Plasticity, CD8-Positive T-Lymphocytes, Regenerative Medicine, Autoantigens, Epigenesis, Genetic, Mice, 0302 clinical medicine, Stem Cell Research - Nonembryonic - Human, Insulin-Secreting Cells, 2.1 Biological and endogenous factors, Immunology and Allergy, Cytotoxic T cell, Aetiology, Cells, Cultured, Cultured, Diabetes, Acquired immune system, Flow Cytometry, Cell biology, medicine.anatomical_structure, Female, Stem cell, Beta cell, Single-Cell Analysis, Type 1, Adult, Pluripotent Stem Cells, Adolescent, Cells, T cell, Immunology, Biology, Autoimmune Disease, Article, 03 medical and health sciences, Young Adult, Genetic, Diabetes Mellitus, Genetics, medicine, Animals, Humans, Epigenetics, Metabolic and endocrine, DNA Methylation, Stem Cell Research, 030104 developmental biology, Diabetes Mellitus, Type 1, T cell differentiation, Immunologic Memory, CD8, Epigenesis, 030215 immunology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c766e2ff25c8b1dacf4caad1134276Test
http://europepmc.org/articles/PMC7183435Test

3

Targeting In Vivo Metabolic Vulnerabilities of Th2 and Th17 Cells Reduces Airway Inflammation

المصدر: J Immunol

مصطلحات موضوعية: Blood Glucose, Male, Glutamine, medicine.medical_treatment, Dexamethasone, Mice, 0302 clinical medicine, Immunology and Allergy, Lung, Cells, Cultured, Glucose Transporter Type 1, biology, Glutaminase, Pyroglyphidae, Alternaria, Drug Synergism, Middle Aged, Healthy Volunteers, Cytokine, Female, medicine.symptom, Bronchoalveolar Lavage Fluid, Immunosuppressive Agents, Adult, Primary Cell Culture, Immunology, Inflammation, Carbohydrate metabolism, Article, Young Adult, 03 medical and health sciences, Th2 Cells, In vivo, medicine, Animals, Humans, House dust mite, business.industry, Glucose transporter, biology.organism_classification, Asthma, T cell cytokine production, respiratory tract diseases, Disease Models, Animal, Case-Control Studies, Th17 Cells, business, Biomarkers, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e9867c920583985c42b42f399d45c2eTest
https://doi.org/10.4049/jimmunol.2001029Test

4

Intracellular immune sensing promotes inflammation via gasdermin D–driven release of a lectin alarmin

المصدر: Nat Immunol

مصطلحات موضوعية: Lipopolysaccharides, Male, 0301 basic medicine, Galectin 1, Lipopolysaccharide, Mice, chemistry.chemical_compound, 0302 clinical medicine, Alarmins, Immunology and Allergy, Caspase, Aged, 80 and over, Mice, Knockout, biology, Intracellular Signaling Peptides and Proteins, Pyroptosis, Middle Aged, Up-Regulation, Cell biology, Necroptosis, Female, Inflammation Mediators, medicine.symptom, Signal transduction, Intracellular, Signal Transduction, Adult, animal structures, Immunology, Inflammation, PTPRC, Article, 03 medical and health sciences, Sepsis, otorhinolaryngologic diseases, medicine, Animals, Humans, Aged, Macrophages, Phosphate-Binding Proteins, Endotoxemia, Mice, Inbred C57BL, Disease Models, Animal, stomatognathic diseases, RAW 264.7 Cells, 030104 developmental biology, chemistry, Case-Control Studies, biology.protein, Leukocyte Common Antigens, HeLa Cells, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcd368de112bdf46f79b07a7aa7e0a0dTest
https://doi.org/10.1038/s41590-020-00844-7Test

5

Activation of mTORC1 at late endosomes misdirects T cell fate decision in older individuals

المؤلفون: Qiong Xia, Huimin Zhang, Jörg J. Goronzy, Timothy M. Gould, Jun Jin, Wenqiang Cao, Cornelia M. Weyand, Daniela Weiskopf, Alba Grifoni, Alessandro Sette, Chulwoo Kim, Xuanying Li

المصدر: Sci Immunol

مصطلحات موضوعية: Adult, CD4-Positive T-Lymphocytes, Male, 0301 basic medicine, Adoptive cell transfer, Endosome, T cell, Immunology, Vesicular Transport Proteins, Autophagy-Related Proteins, Mice, Transgenic, Endosomes, mTORC1, CD8-Positive T-Lymphocytes, Mechanistic Target of Rapamycin Complex 1, Transfection, Article, Large Neutral Amino Acid-Transporter 1, Mice, Young Adult, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Humans, Cells, Cultured, Late endosome, Aged, Aged, 80 and over, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Forkhead Box Protein O1, SARS-CoV-2, Chemistry, COVID-19, Germinal center, General Medicine, Adoptive Transfer, Healthy Volunteers, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, Female, biological phenomena, cell phenomena, and immunity, Lysosomes, Memory T cell, CD8, Signal Transduction, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e04953a5d97e002d06400ddf6cb4899Test
https://doi.org/10.1126/sciimmunol.abg0791Test

6

Host engulfment pathway controls inflammation in inflammatory bowel disease

المؤلفون: Stella-Rita Ibeawuchi, Matheus Pereira, Ranajoy Chattopadhyay, Gajanan D. Katkar, Pradipta Ghosh, Eileen Lim, Sujay Singh, Brigid S. Boland, Soumita Das, William J. Sandborn, Monica Guma, Ying Dunkel, Yash Mittal, Parambir S. Dulai, Ibrahim M Sayed, Katherine Suarez

المصدر: FEBS J
The FEBS journal, vol 287, iss 18

مصطلحات موضوعية: Male, 0301 basic medicine, THP-1 Cells, medicine.medical_treatment, Crohn's Disease, Medical Biochemistry and Metabolomics, Inbred C57BL, Biochemistry, Inflammatory bowel disease, Oral and gastrointestinal, Mice, 0302 clinical medicine, enteroid, 2.1 Biological and endogenous factors, Aetiology, Intestinal Mucosa, Mice, Knockout, Adaptor Proteins, epithelial-immune cell crosstalk, Middle Aged, Colitis, Organoids, medicine.anatomical_structure, ELMO1, Cytokine, 030220 oncology & carcinogenesis, Host-Pathogen Interactions, Cytokines, Female, Tumor necrosis factor alpha, medicine.symptom, Adult, Biochemistry & Molecular Biology, Knockout, Inflammation, Autoimmune Disease, Article, Medicinal and Biomolecular Chemistry, Young Adult, 03 medical and health sciences, inflammatory bowel disease, medicine, Animals, Humans, Molecular Biology, Adaptor Proteins, Signal Transducing, Aged, Lamina propria, business.industry, Inflammatory and immune system, Monocyte, Signal Transducing, monocyte chemoattractant protein 1, Cell Biology, Inflammatory Bowel Diseases, medicine.disease, Epithelium, Mice, Inbred C57BL, microbial sensing and bacterial engulfment, 030104 developmental biology, Gene Expression Regulation, Immunology, Citrobacter rodentium, Biochemistry and Cell Biology, Digestive Diseases, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85bf2fb0feaf80489a05fa877731f4cbTest
https://doi.org/10.1111/febs.15236Test

7

Glutaminase 1 Inhibition Reduces Glycolysis and Ameliorates Lupus‐like Disease in MRL / lpr Mice and Experimental Autoimmune Encephalomyelitis

المؤلفون: Kayaho Maeda, Abel Suárez-Fueyo, Michihito Kono, Nobuya Yoshida, Vasileios C. Kyttaris, George C. Tsokos

المصدر: Arthritis Rheumatol

مصطلحات موضوعية: Adult, CD4-Positive T-Lymphocytes, 0301 basic medicine, Mice, Inbred MRL lpr, Encephalomyelitis, Autoimmune, Experimental, Glutamine, Immunology, In Vitro Techniques, Sulfides, Article, Mice, 03 medical and health sciences, 0302 clinical medicine, Glutaminase, Rheumatology, immune system diseases, Thiadiazoles, medicine, Extracellular, Animals, Humans, Lupus Erythematosus, Systemic, Immunology and Allergy, Glycolysis, Mice, Knockout, 030203 arthritis & rheumatology, Glutaminolysis, Systemic lupus erythematosus, Chemistry, Experimental autoimmune encephalomyelitis, Cell Differentiation, Middle Aged, Hypoxia-Inducible Factor 1, alpha Subunit, medicine.disease, In vitro, Blot, 030104 developmental biology, Cancer research, Th17 Cells, Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71284a6fe547f4787d57536e1ac85eb2Test
https://doi.org/10.1002/art.41019Test

8

Analysis of Results of Specific IgE in 100 Atopic Dermatitis Patients with the Use of Multiplex Examination ALEX2—Allergy Explorer

المؤلفون: Jarmila Čelakovská, R. Vaňková, Josef Bukac, Jan Krejsek, Ctirad Andrýs, Eva Cermakova, Hana Skalská

المصدر: International Journal of Molecular Sciences
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5286, p 5286 (2021)

مصطلحات موضوعية: 0301 basic medicine, Male, Allergy, Lipocalin, ALEX2 Allergy Explorer, medicine.disease_cause, Immunoglobulin E, 0302 clinical medicine, Allergen, Fel d 1, Biology (General), Spectroscopy, Sensitization, Czech Republic, severity of atopic dermatitis, biology, atopic dermatitis, Pyroglyphidae, General Medicine, Atopic dermatitis, Allergen extract, Middle Aged, molecular components, Computer Science Applications, Chemistry, medicine.anatomical_structure, Pollen, Female, Adult, Adolescent, QH301-705.5, Catalysis, Article, Dermatitis, Atopic, Inorganic Chemistry, 03 medical and health sciences, disturbed epidermal barrier, medicine, Animals, Humans, Physical and Theoretical Chemistry, Molecular Biology, QD1-999, Aged, Skin Tests, allergic rhinitis, Organic Chemistry, asthma bronchiale, Allergens, medicine.disease, Rhinitis, Allergic, Asthma, 030104 developmental biology, 030228 respiratory system, Immunology, biology.protein

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::476ac6d939dad0a117cd309189810e00Test

9

Differential expression of CD49a and CD49b determines localization and function of tumor-infiltrating CD8(+) T cells

المؤلفون: Ukpong B. Eyo, Robin S. Lindsay, Anthony B. Rodriguez, Amanda M. Briegel, Sjoerd H. van der Burg, Craig L. Slingluff, Mark R. Conaway, Salwador Cyranowski, Cornelis J. M. Melief, Victor H. Engelhard, Melanie R. Rutkowski, Marit M. Melssen, Katarzyna Stasiak

المصدر: Cancer Immunology Research, 9(5), 583-597. AMER ASSOC CANCER RESEARCH
Cancer Immunol Res

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d86db6690928ddb94b7e903781f15b70Test
http://hdl.handle.net/1887/3209072Test

10

Antigen-specific immunotherapy combined with a regenerative drug in the treatment of experimental type 1 diabetes

المؤلفون: Federico Vázquez, Rosa-Maria Ampudia, Silvia Rodriguez-Fernandez, Laia Gomez-Muñoz, David Perna-Barrull, Marta Vives-Pi, Ruth M. Risueño, Daniel Maspoch, Irma Pujol-Autonell, Mary Cano-Sarabia, Eva Aguilera, Adrian Villalba

المساهمون: Fundació La Marató de TV3, Agencia Estatal de Investigación (España), Ministerio de Ciencia, Innovación y Universidades (España)

المصدر: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Scientific Reports
Digital.CSIC. Repositorio Institucional del CSIC
instname
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Combination therapy, medicine.medical_treatment, Immunology, lcsh:Medicine, Nod, Neogenesis, Article, Diabetes Mellitus, Experimental, 03 medical and health sciences, Mice, Young Adult, 0302 clinical medicine, Endocrinology, Mice, Inbred NOD, Insulin-Secreting Cells, medicine, Animals, Humans, Insulin, lcsh:Science, NOD mice, Type 1 diabetes, Multidisciplinary, biology, Liraglutide, business.industry, lcsh:R, Transdifferentiation, Immunotherapy, medicine.disease, biology.organism_classification, Combined Modality Therapy, 030104 developmental biology, Diabetes Mellitus, Type 1, Treatment Outcome, 030220 oncology & carcinogenesis, Liposomes, lcsh:Q, Female, business, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60fa56655a866ea18cee51de4a9ff1a9Test
https://ddd.uab.cat/record/236025Test

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