المؤلفون: Raluca Pais, Rachel Ostroff, Stephen Harrison, Lars Friis Mikkelsen, Elisabeth Erhardtsen, Sudha Shankar, Kimmo Porthan, Jérôme Boursier, Antonia Sinisi, Michael Kalutkiewicz, Sven Francque, Miljen Martic, Vanessa Pellegrinelli, Phil N. Newsome, Guido Hanauer, Hannele Yki-Järvinen, Rebecca Darlay, Joel Myers, Carla Yunis, Salvatore Petta, Mette Skalshøi Kjær, Pablo Ortiz, Ann K. Daly, James H. Clark, Dina Tiniakos, Yasaman Vali, Hadi Zafarmand, Matej Orešič, Maurizio Parola, Estelle Sandt, Lori L. Jennings, Matt Kelly, Tuulia Hyötyläinen, Detlef Schuppan, Céline Fournier, Chiara Rosso, Diane E. Shevell, Maria Manuela Tonini, Paul Hockings, Aidan McGlinchey, Salma Akhtar, Mette Juul Fisker, Morten A. Karsdal, Diane Whalley, Melissa R. Miller, Aldo Trylesinski, Mattias Ekstedt, Stefan Neubauer, Jeremy M. Palmer, Partho Sen, Michael Pavlides, Per Qvist, Isabel Fernández, Luca Miele, Fabio Marra, Stergios Kechagias, Richard Torstenson, Katherine Johnson, Jean-François Dufour, Elisabetta Bugianesi, M. Julia Brosnan, George V. Papatheodoridis, Kay M. Pepin, Daniel Guldager Kring Rasmussen, Henrik Landgren, Rachel Queen, Simon Cockell, Michael Allison, Patrick M.M. Bossuyt, Rocío Gallego-Durán, Christian Rosenquist, Leigh Alexander, Elizabeth Shumbayawonda, Michele Vacca, Antonio Vidal-Puig, David Wenn, Rémy Hanf, Oscar Millet, Michalina Zatorska, R. Myers, José M. Mato, Jenny Lee, Theresa Tuthill, James Twiss, Ramy Younes, Peter Leary, Lynda Doward, Kristy Wonders, Guruprasad P. Aithal, Sarah Charlton, Vlad Ratziu, Cecília M. P. Rodrigues, Christian Trautwein, Helena Cortez-Pinto, Gideon Ho, Matt J. Barter, Judith Ertle, Jörn M. Schattenberg, Maria-Magdalena Balp, Yang-Lin Liu, Clifford A. Brass, Olivier Govaere, Amalia Gastaldelli, Sergio Rodriguez Cuenca, Pierre Chaumat, Fiona Oakley, Luca Valenti, Simon J. Cockell, Saskia W.C. van Mil, Ferenc E. Mózes, Andreas Geier, Timothy Hardy, Pierre Bedossa, Andrea Dennis, Richard L. Ehman, Charlotte Erpicum, Karine Clément, Jeremy F. L. Cobbold, Christopher P. Day, Rajarshi Banerjee, Manuel Romero-Gómez, Quentin M. Anstee, Adriaan G. Holleboom, Heather J. Cordell, Kevin L. Duffin, Diana Julie Leeming

المساهمون: Epidemiology and Data Science, APH - Methodology, APH - Personalized Medicine, Vascular Medicine, ACS - Diabetes & metabolism, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, APH - Aging & Later Life, ARD - Amsterdam Reproduction and Development, Graduate School, Investigators, LITMUS Consortium, Johnson K., Leary P.J., Govaere O., Barter M.J., Charlton S.H., Cockell S.J., Tiniakos D., Zatorska M., Bedossa P., Brosnan M.J., Cobbold J.F., Ekstedt M., Aithal G.P., Clement K., Schattenberg J.M., Boursier J., Ratziu V., Bugianesi E., Anstee Q.M., Daly A.K., Clark J., Cordell H.J., Darlay R., Day C.P., Hardy T., Liu Y.-L., Oakley F., Palmer J., Queen R., Wonders K., Bossuyt P.M., Holleboom A.G., Zafarmand H., Vali Y., Lee J., Pais R., Schuppan D., Allison M., Cuenca S.R., Pellegrinelli V., Vacca M., Vidal-Puig A., Hyotylainen T., McGlinchey A., Oresic M., Sen P., Mato J., Millet O., Dufour J.-F., Harrison S., Neubauer S., Pavlides M., Mozes F., Akhtar S., Banerjee R., Kelly M., Shumbayawonda E., Dennis A., Erpicum C., Romero-Gomez M., Gallego-Duran R., Fernandez I., Karsdal M., Leeming D., Fisker M.J., Erhardtsen E., Rasmussen D., Qvist P., Sinisi A., Sandt E., Tonini M.M., Parola M., Rosso C., Marra F., Gastaldelli A., Francque S., Kechagias S., Yki-Jarvinen H., Porthan K., van Mil S., Papatheodoridis G., Cortez-Pinto H., Valenti L., Petta S., Miele L., Geier A., Trautwein C., Hockings P., Newsome P., Wenn D., Pereira Rodrigues C.M., Hanf R., Chaumat P., Rosenquist C., Trylesinski A., Ortiz P., Duffin K., Yunis C., Miller M., Tuthill T., Ertle J., Younes R., Alexander L., Ostroff R., Kjaer M.S., Mikkelsen L.F., Brass C., Jennings L., Balp M.-M., Martic M., Hanauer G., Shankar S., Torstenson R., Fournier C., Ehman R., Kalutkiewicz M., Pepin K., Myers J., Shevell D., Ho G., Landgren H., Myers R., Doward L., Whalley D., Twiss J., Miller, Melissa, Tuthill, Theresa, Ertle, Judith, Younes, Ramy, Alexander, Leigh, Ostroff, Rachel, Kjær, Mette Skalshøi, Mikkelsen, Lars Friis, Brass, Clifford, Jennings, Lori, Balp, Maria-Magdalena, Martic, Miljen, Hanauer, Guido, Shankar, Sudha, Torstenson, Richard, Fournier, Céline, Ehman, Richard, Kalutkiewicz, Michael, Pepin, Kay, Myers, Joel, Shevell, Diane, Ho, Gideon, Landgren, Henrik, Myers, Rob, Doward, Lynda, Whalley, Diane, Twiss, James, Clark, James, Cordell, Heather J., Darlay, Rebecca, Day, Christopher P., Hardy, Tim, Liu, Yang-Lin, Oakley, Fiona, Palmer, Jeremy, Queen, Rachel, Wonders, Kristy, Bossuyt, Patrick M., Holleboom, Adriaan G., Zafarmand, Hadi, Vali, Yasaman, Lee, Jenny, Clement, Karine, Pais, Raluca, Schuppan, Detlef, Allison, Michael, Cuenca, Sergio Rodriguez, Pellegrinelli, Vanessa, Vacca, Michele, Vidal-Puig, Antonio, Hyötyläinen, Tuulia, McGlinchey, Aidan, Orešič, Matej, Sen, Partho, Mato, Jose, Millet, Óscar, Dufour, Jean-Francois, Harrison, Stephen, Neubauer, Stefan, Pavlides, Michael, Mozes, Ferenc, Akhtar, Salma, Banerjee, Rajarshi, Kelly, Matt, Shumbayawonda, Elizabeth, Dennis, Andrea, Erpicum, Charlotte, Romero-Gomez, Manuel, Gallego-Durán, Rocío, Fernández, Isabel, Karsdal, Morten, Leeming, Diana, Fisker, Mette Juul, Erhardtsen, Elisabeth, Rasmussen, Daniel, Qvist, Per, Sinisi, Antonia, Sandt, Estelle, Tonini, Maria Manuela, Parola, Maurizio, Rosso, Chiara, Marra, Fabio, Gastaldelli, Amalia, Francque, Sven, Kechagias, Stergios, Yki-Järvinen, Hannele, Porthan, Kimmo, van Mil, Saskia, Papatheodoridis, George, Cortez-Pinto, Helena, Valenti, Luca, Petta, Salvatore, Miele, Luca, Geier, Andreas, Trautwein, Christian, Hockings, Paul, Newsome, Phil, Wenn, David, Pereira Rodrigues, Cecília Maria, Hanf, Rémy, Chaumat, Pierre, Rosenquist, Christian, Trylesinski, Aldo, Ortiz, Pablo, Duffin, Kevin, Yunis, Carla

المصدر: JHEP Reports, 4(2):100409. Elsevier
JHEP Reports
JHEP Reports, Vol 4, Iss 2, Pp 100409-(2022)
JHEP reports 4(2), 100409 (2022). doi:10.1016/j.jhepr.2021.100409

مصطلحات موضوعية: SCORING SYSTEM, CPM, counts per million, AUROC, area under the receiver operating characteristic, RC799-869, AST, aspartate aminotransferase, MicroRNA, Non-alcoholic fatty liver disease, Biomarker, Sequencing, TGF-β, transforming growth factor-beta, Gastroenterology, STEATOHEPATITIS, Liver disease, 0302 clinical medicine, Fibrosis, miRNA, microRNA, logFC, log2 fold change, FIBROSIS, Immunology and Allergy, 0303 health sciences, education.field_of_study, NAS, NAFLD activity score, medicine.diagnostic_test, Fatty liver, GTEx, Genotype-Tissue Expression, Diseases of the digestive system. Gastroenterology, 3. Good health, Real-time polymerase chain reaction, Biomarker, MicroRNA, Non-alcoholic fatty liver disease, Sequencing, Liver biopsy, ACID, Biomarker (medicine), 030211 gastroenterology & hepatology, Life Sciences & Biomedicine, Research Article, EXPRESSION, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, NASH, non-alcoholic steatohepatitis, Population, Gastroenterology and Hepatology, SAF, steatosis–activity–fibrosis, VALIDATION, ER, endoplasmic reticulum, 03 medical and health sciences, cDNA, complementary DNA, Internal medicine, ALT, alanine aminotransferase, Gastroenterologi, Internal Medicine, medicine, NAFL, non-alcoholic fatty liver, ALGORITHM, FIB-4, fibrosis-4, education, 030304 developmental biology, PCA, principal component analysis, Science & Technology, Gastroenterology & Hepatology, Hepatology, business.industry, FC, fold change, medicine.disease, digestive system diseases, FLIP, fatty liver inhibition of progression, Ct, cycle threshold, Steatosis, qPCR, quantitative PCR, business

وصف الملف: application/pdf; Electronic-eCollection

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c39a3a5921e0d464a7b2b93c40ef52cTest
https://pure.amc.nl/en/publications/increased-serum-mir193a5p-during-nonalcoholic-fatty-liver-disease-progressionTest(bd6dd66c-d686-4b4d-be46-956a848f1f3b).html

المؤلفون: Sujit Mukherjee, Evangelos Triantafyllou, Oltin T Pop, Fabien Zoulim, Enes Tunc, Alberto Quaglia, Arjuna Singanayagam, Wafa Khamri, Mark Thursz, Tie Zheng Hou, Fanny Lebossé, Julia Wendon, Rooshi Nathwani, Charalambos G. Antoniades, Cathrin Gudd, Naveenta Kumar, A. Dhar

المساهمون: Imperial College London, King‘s College London, Centre de Recherche en Cancérologie de Lyon (UNICANCER/CRCL), Centre Léon Bérard [Lyon]-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), University College of London [London] (UCL), Manship, Brigitte, BRC ITMAT Funding Scheme, Medical Research Council

المصدر: EBioMedicine
EBioMedicine, 2019, 49, pp.258-268. ⟨10.1016/j.ebiom.2019.10.011⟩

مصطلحات موضوعية: CHRONIC LIVER-FAILURE, 0301 basic medicine, Liver Cirrhosis, Male, Cirrhosis, Research paper, Transcription, Genetic, Apoptosis, Research & Experimental Medicine, CD8-Positive T-Lymphocytes, Chronic liver disease, Severity of Illness Index, 0302 clinical medicine, INFECTION, Ascites, Cytotoxic T cell, Myeloid Cells, CD8(+)T cells, ALD, alcohol-related liver disease, NEUTROPHILS, CD8(+) T cells, medicine.diagnostic_test, ACLF, acute-on-chronic-liver disease, General Medicine, Middle Aged, 3. Good health, CD8+T cells, Phenotype, Treatment Outcome, Medicine, Research & Experimental, 030220 oncology & carcinogenesis, SURVIVAL, CLD, Chronic liver disease, Female, Disease Susceptibility, medicine.symptom, Peritoneum, Life Sciences & Biomedicine, EXPRESSION, CAID, cirrhosis-associated immune dysfunction, NASH, non-alcoholic steatohepatitis, Cirrhosis-associated immune dysfunction, [SDV.CAN]Life Sciences [q-bio]/Cancer, AAH, acute alcoholic hepatitis, Peripheral blood mononuclear cell, General Biochemistry, Genetics and Molecular Biology, Flow cytometry, 03 medical and health sciences, Medicine, General & Internal, Immune system, [SDV.CAN] Life Sciences [q-bio]/Cancer, General & Internal Medicine, medicine, HV, Healthy volunteers, Humans, Aged, Cell Proliferation, Inflammation, Science & Technology, business.industry, ELD, End-stage-liver diseases, HLA-DR Antigens, medicine.disease, AD, acute decompensation, 030104 developmental biology, Immunology, Natural Killer T-Cells, business, CD8, Biomarkers, PMNs, polymorphonuclear neutrophils

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9318081e284f95b31ce34f205764d8dbTest
http://europepmc.org/articles/PMC6945243Test

المؤلفون: Lucia Parlati, Catherine Postic, Marion Régnier, Hervé Guillou

المساهمون: LESUR, Hélène, Impact du métabolisme des acides gras des tissus adipeux et du foie sur l'insulinorésistance - - HepAdialogue2017 - ANR-17-CE14-0015 - AAPG2017 - VALID, Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Catholique de Louvain = Catholic University of Louvain (UCL), ToxAlim (ToxAlim), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Ecole d'Ingénieurs de Purpan (INPT - EI Purpan), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Toxicologie Intégrative & Métabolisme (ToxAlim-TIM), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3), Lucia Parlati and Catherine Postic received funding from the French association for the study of the liver (AFEF). Catherine Postic and Herve Guillou received funding from the Agence Nationale de la Recherche (ANR-17-CE14-0015Hepadialogue)., ANR-17-CE14-0015,HepAdialogue,Impact du métabolisme des acides gras des tissus adipeux et du foie sur l'insulinorésistance(2017), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP)

المصدر: JHEP Reports
JHEP Reports Innovation in Hepatology
JHEP Reports Innovation in Hepatology, 2021, 3 (6), pp.100346. ⟨10.1016/j.jhepr.2021.100346⟩
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (6), pp.100346. ⟨10.1016/j.jhepr.2021.100346⟩

مصطلحات موضوعية: HFD, high-fat diet, SREBP-1c, [SDV]Life Sciences [q-bio], Disease, Review, ACC, acetyl-CoA carboxylase, ASK1, apoptosis signal-regulating kinase 1, Chronic liver disease, Bioinformatics, ChREBP, carbohydrate responsive element–binding protein, PPARα, NEFA, TNF-α, tumour necrosis factor-α, 0302 clinical medicine, Fibrosis, Immunology and Allergy, Medicine, IL-, interleukin, VLDL, very low-density lipoprotein, 0303 health sciences, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, NEFA, non-esterified fatty acid, Fatty liver, Gastroenterology, NASH, lipotoxicity, FAS, fatty acid synthase, animal models, 3. Good health, [SDV] Life Sciences [q-bio], PY, persons/years, Lipotoxicity, FXR, Saturated fatty acid, JNK, c-Jun N-terminal kinase, 030211 gastroenterology & hepatology, LXR, CAP, controlled attenuation parameter, HSL, hormone-sensitive lipase, HSC, hepatic stellate cells, GGT, gamma glutamyltransferase, NAFLD, non-alcoholic fatty liver disease, ChREBP, NASH, non-alcoholic steatohepatitis, SFA, saturated fatty acid, TCA, tricarboxylic acid, Phf2, histone demethylase plant homeodomain finger 2, digestive system, 03 medical and health sciences, glucotoxicity, FXR, farnesoid X receptor, NAFLD, FFA, free fatty acid, Internal Medicine, RCT, randomised controlled trial, Liver X receptor, PPARa, 030304 developmental biology, FGF21, fibroblast growth factor-21, MCD, methionine- and choline-deficient, HVPG, hepatic venous pressure gradient, Hepatology, business.industry, PUFAs, polyunsaturated fatty acids, nutritional and metabolic diseases, TLR4, Toll-like receptor 4, SCD1, stearoyl-CoA desaturase-1, medicine.disease, digestive system diseases, PPARα, peroxisome proliferator-activated receptor-α, SREBP-1c, sterol regulatory element–binding protein-1c, Steatosis, LXR, liver X receptor, business, HCC, hepatocellular carcinoma, MUFA, monounsaturated fatty acids, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba31673956635c337dc60791ff712432Test
https://pubmed.ncbi.nlm.nih.gov/34667947Test

المؤلفون: Manuel Romero-Gómez, Patrizia Carrieri, Mattias Ekstedt, Shira Zelber-Sagi, Katja Novak, Vlad Ratziu, Quentin M. Anstee, Frank Tacke, Adam Palayew, Jeffrey V. Lazarus, Helena Cortez-Pinto, Giulio Marchesini

المساهمون: Instituto de Salud Global - Institute For Global Health [Barcelona] (ISGlobal), University of Barcelona, McGill University = Université McGill [Montréal, Canada], Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale (SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Linköping University (LIU), Alma Mater Studiorum University of Bologna (UNIBO), Istituto di ricovero e cura a carattere scientifico Azienda Ospedaliera Universitaria 'San Martino' (IRCCS AOU San Martino), University Medical Centre Ljubljana [Ljubljana, Slovenia] (UMCL), Sorbonne Université - Faculté de Médecine (SU FM), Sorbonne Université (SU), CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centro de Investigación Biomédica en Red en el Área temática de Enfermedades Hepáticas y Digestivas (CIBERehd), Liver Unit, Clínica Universitaria, CIBER-EHD, Hospital Universitario Virgen del Rocío [Sevilla], Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], University of Haifa [Haifa], Universidade de Lisboa (ULISBOA), Newcastle University [Newcastle], Lazarus J.V., Palayew A., Carrieri P., Ekstedt M., Marchesini G., Novak K., Ratziu V., Romero-Gomez M., Tacke F., Zelber-Sagi S., Cortez-Pinto H., Anstee Q.M., EASL International Liver Foundation, Gilead Sciences, Allergan Foundation, Bristol-Myers Squibb, Pfizer, Resoundant, Intercept Pharmaceuticals, Genfit, Ministerio de Ciencia, Innovación y Universidades (España), Instituto de Salud Carlos III, European Commission, Generalitat de Catalunya, NIHR Biomedical Research Centre (UK), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Universidade de Lisboa = University of Lisbon (ULISBOA), Repositório da Universidade de Lisboa, Gestionnaire, Hal Sorbonne Université

المصدر: JHEP Reports Innovation in Hepatology
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (2), pp.100234. ⟨10.1016/j.jhepr.2021.100234⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
JHEP Reports
JHEP Reports, Vol 3, Iss 2, Pp 100234-(2021)

مصطلحات موضوعية: ESPEN, type 2 diabetes mellitus, EASL, European Association for the Study of the Liver, [SDV]Life Sciences [q-bio], Disease, Multiple joint correspondence analysi, WHO, 0302 clinical medicine, Non-alcoholic fatty liver disease, Liver health, Multiple joint correspondence analysis, Policy preparedness, Health policy, Metabolic-associated fatty liver disease, Non-alcoholic steatohepatitis, Europe, Multidisciplinary approach, EASD, European Association for the Study of Diabetes, European Association for the Study of Diabetes, Epidemiology, Immunology and Allergy, Medicine, European Association for the Study of Obesity, European Society of Clinical Nutrition and Metabolism, EEA, EASO, European Association for the Study of Obesity, media_common, Gastroenterology, NASH, food and beverages, ESPEN, European Society of Clinical Nutrition and Metabolism, 3. Good health, [SDV] Life Sciences [q-bio], 030220 oncology & carcinogenesis, Preparedness, 030211 gastroenterology & hepatology, Research Article, European Association for the Study of the Liver, EEA, European Economic Area, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, EASD, NASH, non-alcoholic steatohepatitis, multiple correspondence analysis, T2DM, Gastroenterology and Hepatology, EASL, World Health Organization, digestive system, WHO, World Health Organization, European Economic Area, 03 medical and health sciences, Environmental health, EU, European Union, NAFLD, Gastroenterologi, Internal Medicine, media_common.cataloged_instance, European Union, lcsh:RC799-869, European union, MCA, multiple correspondence analysis, Hepatology, business.industry, Public health, MCA, nutritional and metabolic diseases, non-alcoholic fatty liver disease, T2DM, type 2 diabetes mellitus, medicine.disease, Obesity, digestive system diseases, EASO, lcsh:Diseases of the digestive system. Gastroenterology, business, EU, Non-alcoholic steatohepatiti

وصف الملف: ELETTRONICO; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::237265ca3a905978c88b2731dd069191Test
https://hal.sorbonne-universite.fr/hal-03174867Test

المؤلفون: Carrie E. McCurdy, Kenneth N. Maclean, Paul Kievit, Bryan C. Bergman, Rachel C. Janssen, Peter R. Baker, Christopher M. Mulligan, Tyler Dean, Diana L. Takahashi, Travis Nemkov, Kjersti Aagaard, Hua Jiang, Stephanie R. Wesolowski, Angelo D'Alessandro, Jacob E. Friedman

المصدر: Molecular Metabolism, Vol 18, Iss, Pp 25-41 (2018)
Molecular Metabolism

مصطلحات موضوعية: 0301 basic medicine, Steatosis, VIP, variable importance in projection, Hypoxemia, AUC, area under the curve, PC, phosphatidylcholine, 0302 clinical medicine, WSD, Western-style diet, Non-alcoholic Fatty Liver Disease, Pregnancy, Fetal programming, Hyperlipidemia, DAG, diacylglyceride, VLDL, very low-density lipoprotein, Hypoxia, 2. Zero hunger, TG, triglyceride, NEFA, non-esterified fatty acid, NHP, non-human primate, Fatty liver, 3. Good health, Liver, Lipotoxicity, CON, control, OB-WSD, Western-style diet induced obesity group, IV-GTT, intravenous glucose tolerance test, Prenatal Exposure Delayed Effects, Original Article, Female, Diet, Healthy, PLS-DA, partial least squares discriminant analysis, TCA, tricarboxylic acid cycle, NAFLD, non-alcoholic fatty liver disease, lcsh:Internal medicine, medicine.medical_specialty, Offspring, NASH, non-alcoholic steatohepatitis, Citric Acid Cycle, Metabolomic, 030209 endocrinology & metabolism, DNL, de novo lipogenesis, TBARs, thiobarbituric acid reactive substances, OB-DR, diet reversal group, 03 medical and health sciences, Fetus, Internal medicine, medicine, TBARS, Animals, Obesity, AA, amino acid, lcsh:RC31-1245, Molecular Biology, Triglycerides, business.industry, Gluconeogenesis, Maternal Nutritional Physiological Phenomena, Cell Biology, medicine.disease, Oxidative Stress, 030104 developmental biology, Endocrinology, Diet, Western, Macaca, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06dccd8288a52f01636dbe7fd72ba0fTest
https://doi.org/10.1016/j.molmet.2018.09.008Test

المؤلفون: Miguel López, Rubén Nogueiras, Xabier Buqué, Maria J. Gonzalez-Rellan, Daniel Beiroa, Patricia Aspichueta, Uxia Fernandez, Begoña Porteiro, Rosalía Gallego, Carlos Dieguez, Guadalupe Sabio, Marcos F. Fondevila, Johan Fernø, Ana Senra, Alfonso Mora

المساهمون: Ministerio de Economía y Competitividad (España), Xunta de Galicia (España), Heise Vest RHF, Comunidad de Madrid (España), Basque Government (España), Fundación AstraZeneca, Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF), Unión Europea. Comisión Europea, Centro de Investigación Biomedica en Red - CIBER

المصدر: Molecular Metabolism, Vol 8, Iss, Pp 132-143 (2018)
Molecular Metabolism
Repisalud
Instituto de Salud Carlos III (ISCIII)

مصطلحات موضوعية: 0301 basic medicine, pIRE, Inositol-requiring enzyme 1 α, pJNK, phospho c-Jun N-terminal kinase, ACC, acetyl-CoA carboxylase, AST, aspartate aminotransferase, XBP1s, X-box binding protein 1, Abcd1, ATP binding cassette subfamily D member 1, Pharmacology, ER stress, endoplasmic reticulum stress, NFκβ, nuclear factor kappa b, FA, free fatty acid, Mice, Liver disease, UPR, unfolded protein response, 0302 clinical medicine, HFD, high fat diet, Non-alcoholic Fatty Liver Disease, Nonalcoholic fatty liver disease, DG, diacylglycerol, Topoisomerase II Inhibitors, IL6, initerleukin 6, Beta oxidation, Acadm, acyl-CoA deshydrogenase, medium chain, GFP, green fluorescent protein, IL10, interleukin 10, Acox, acyl-CoA oxidase 1, TG, triglyceride, Ad, adenovirus, Hep G2 Cells, Acadl, acyl-CoA deshydrogenase, long-chain, i.p., intraperitoneal, FAS, fatty acid synthase, 3. Good health, Liver, Pparα, peroxisome proliferator activated receptor alpha, JNK, c-Jun N-terminal kinase, Lipogenesis, DOX, Doxorubicin, DN, dominant negative, Original Article, ApoB, apolipoprotein b, Quer, quercetin, NAFLD, non-alcoholic fatty liver disease, lcsh:Internal medicine, ASM, acid-soluble metabolites, NASH, non-alcoholic steatohepatitis, TNFα, tumor necrosis factor alpha, GAPDH, glyceraldehyde-3-phosphate deshydrogenase, AUC, area under curve, Diet, High-Fat, Cell Line, SPF, specific pathogen free room, 03 medical and health sciences, GTT, glucose test tolerance, ALT, alanine aminotransferase, AAV8, adeno-associated virus serotype 8, medicine, Animals, Humans, Obesity, EC, sterified cholesterol, lcsh:RC31-1245, Molecular Biology, MCD, methionine-choline deficient diet, CHOP, C/EBP-homologous protein, Inflammation, business.industry, OA, oleic acid, Lipid metabolism, DIO, diet-induced obesity, Cell Biology, Lipid Metabolism, medicine.disease, CDHFD, choline-deficient high fat diet, Mice, Inbred C57BL, 030104 developmental biology, Doxorubicin, pACC, phospho acetyl-CoA carboxylase, Hepatic stellate cell, BSA, bovine serum albumin, Tumor Suppressor Protein p53, Steatohepatitis, Steatosis, business, Fatp2, solute carrier family 27 (fatty acid transporter) member 2, IL1β, interleukin 1beta, 030217 neurology & neurosurgery, ITT, insulin test tolerance

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df7642e1971aebb46c881386960e7affTest
http://www.sciencedirect.com/science/article/pii/S2212877817310116Test

المؤلفون: Jérôme Boursier, Emmanuel Tsochatzis

المساهمون: Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)

المصدر: JHEP Reports Innovation in Hepatology
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (2), pp.100219. ⟨10.1016/j.jhepr.2020.100219⟩
JHEP Reports

مصطلحات موضوعية: Cirrhosis, Cost effectiveness, [SDV]Life Sciences [q-bio], NICE, National Institute of Clinical Excellence, Nice, Review, AST, aspartate aminotransferase, Disease, Patient pathway, ELF, enhanced liver fibrosis, 0302 clinical medicine, Immunology and Allergy, Medicine, NFS, NAFLD fibrosis score, ALD, alcohol-related liver disease, ComputingMilieux_MISCELLANEOUS, computer.programming_language, 0303 health sciences, NAS, NAFLD activity score, Case-finding, Fatty liver, Gastroenterology, Awareness, Primary care, TE, transient elastography, 3. Good health, Screening, FIB-4, 030211 gastroenterology & hepatology, Elastography, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, NASH, non-alcoholic steatohepatitis, Liver fibrosis, QALY, quality-adjusted life year, 03 medical and health sciences, ALT, alanine aminotransferase, Type 2 diabetes mellitus, NIT, non-invasive test, Internal Medicine, GP, general practitioner, FIB-4, fibrosis-4, Intensive care medicine, 030304 developmental biology, Hepatology, business.industry, Type 2 Diabetes Mellitus, T2DM, type 2 diabetes mellitus, medicine.disease, Quality-adjusted life year, Cost-effectiveness, Transient elastography, business, computer

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::998a5dc5ae8854bb83716af6e6873dc7Test
https://doi.org/10.1016/j.jhepr.2020.100219Test

المؤلفون: Yemi Oluboyede, Gulnar Fattakhova, Lorraine McSweeney, Luke Vale, Lynda C. Doward, Fiona Beyer, Clifford A. Brass, Quentin M. Anstee, Matthew Breckons, Laura Ternent, Maria-Magdalena Balp, Arun J. Sanyal

المصدر: JHEP Reports
JHEP Reports, Vol 2, Iss 3, Pp-(2020)

مصطلحات موضوعية: medicine.medical_treatment, Disease, Liver disease, 0302 clinical medicine, Immunology and Allergy, 030212 general & internal medicine, Non-alcoholic steatohepatitis, education.field_of_study, Gastroenterology, PRO, patient-reported outcome, LDSI, liver disease symptom index, 3. Good health, health-related quality of life, Cirrhosis, 030211 gastroenterology & hepatology, Patient-reported outcome, SF-36, short form health profile 36, Research Article, FDA, United States Food and Drug Administration, RI, researcher interpretation, HRQoL, health-related quality of life, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, SF-36, NASH, non-alcoholic steatohepatitis, Population, liver, digestive system, Support group, MS, multiple sclerosis, 03 medical and health sciences, Quality of life (healthcare), NAFLD, PHAQ, patient-reported outcome measurement information system health assessment questionnaire, Internal Medicine, medicine, NAFL, non-alcoholic fatty liver, CLDQ, chronic liver disease questionnaire, lcsh:RC799-869, Intensive care medicine, education, patient-reported outcome measures, Hepatology, business.industry, nutritional and metabolic diseases, medicine.disease, QoL, quality of life, Mental health, digestive system diseases, FIS, fatigue impact scale, PROM, patient-reported outcome measure, EMA, European Medicines Agency, COSMIN, The COnsensus-based Standards for the selection of health Measurement INstruments, lcsh:Diseases of the digestive system. Gastroenterology, business, LDQoL, liver disease quality of life questionnaire

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee751f2b6ffd99b10142118b951f0fcdTest
https://doi.org/10.1016/j.jhepr.2020.100099Test

المؤلفون: Felix Stickel, Maria L. Balmer, Jeannine Joneli, Wolfgang Thormann, Alain M. Schoepfer, Jean-François Dufour

المصدر: Clinical Science (London, England : 1979)
Clinical science (London England : 1979)

مصطلحات موضوعية: Liver Cirrhosis, Male, Cirrhosis, BMI, body mass index, AST, aspartate aminotransferase, Serum Hyaluronic Acid, Chronic liver disease, Body Mass Index, Liver disease, 0302 clinical medicine, Blood serum, hepatic fibrosis, AdipoR, adiponectin receptor, Prospective Studies, Hyaluronic Acid, 2. Zero hunger, 0303 health sciences, Anthropometry, Liver Diseases, Fatty liver, General Medicine, Middle Aged, 3. Good health, TG, triacylglycerol, HOMA, homoeostasis model assessment, Elasticity Imaging Techniques, 030211 gastroenterology & hepatology, Female, non-alcoholic fatty liver disease (NAFLD), Research Article, Adult, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, ANCOVA, analysis of covariance, NASH, non-alcoholic steatohepatitis, S7, S3, metabolic syndrome, Bile Acids and Salts, Diagnosis, Differential, 03 medical and health sciences, Sex Factors, Internal medicine, ALT, alanine aminotransferase, medicine, Humans, 030304 developmental biology, Adiponectin, adiponectin, business.industry, cirrhosis, nutritional and metabolic diseases, chronic liver disease, medicine.disease, Fatty Liver, Endocrinology, Chronic Disease, Steatohepatitis, business, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57760eaf2f7c8755862836a259985d38Test
https://pubmed.ncbi.nlm.nih.gov/20524936Test

المؤلفون: Mariuca Vasa-Nicotera, Elsa Solà, Juan José Lozano, Pau Sancho-Bru, Sara Fernández, Jonel Trebicka, Elisa Pose, Pere Ginès, Pedro Castro, Delia Blaya, Julia Sidorova, Robert Schierwagen, Joan Caballería, Mar Coll, Christian Jansen, Isabel Graupera

المصدر: JHEP Reports
JHEP Reports, Vol 3, Iss 2, Pp 100233-(2021)
Blaya, D, Pose, E, Coll, M, Lozano, J J, Graupera, I, Schierwagen, R, Jansen, C, Castro, P, Fernandez, S, Sidorova, J, Vasa-Nicotera, M, Solà, E, Caballería, J, Trebicka, J, Ginès, P & Sancho-Bru, P 2021, ' Profiling circulating microRNAs in patients with cirrhosis and acute-on-chronic liver failure ', JHEP Reports, vol. 3, no. 2, 100233 . https://doi.org/10.1016/j.jhepr.2021.100233Test

مصطلحات موضوعية: medicine.medical_specialty, Cirrhosis, NASH, non-alcoholic steatohepatitis, Encephalopathy, AST, aspartate aminotransferase, Disease, FoxO, forkhead box O, Chronic liver disease, Gastroenterology, Non-coding RNAs, CXCL10, C-X-C motif chemokine ligand 10, MELD, model for end-stage liver disease, 03 medical and health sciences, Liver disease, 0302 clinical medicine, Model for End-Stage Liver Disease, ALT, alanine aminotransferase, TIPS, transjugular intrahepatic portosystemic shunt, Internal medicine, Internal Medicine, medicine, Immunology and Allergy, Decompensation, lcsh:RC799-869, EF CLIF, European Foundation for the Study of Chronic Liver Failure, INR, International Normalised Ratio, TGF, transforming growth factor, 030304 developmental biology, PBMCs, peripheral blood mononuclear cells, PCA, principal component analysis, 0303 health sciences, LDH, lactate dehydrogenase, Hepatology, business.industry, medicine.disease, 3. Good health, Circulating MicroRNA, ACLF, acute-on-chronic liver failure, 030220 oncology & carcinogenesis, lcsh:Diseases of the digestive system. Gastroenterology, qPCR, quantitative PCR, business, Liver decompensation, Biomarkers, MAPK, mitogen-activated protein kinase, Research Article

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87d4e48212cb48cff68c240ced3c4227Test