المؤلفون: Claire F. Verschraegen, Jiahan Ding, Wen Jia Zuo, Jianjun Zou, Yi Xiao, Virginia G. Kaklamani, Zhong Hua Wang, Yi-Zhou Jiang, Ding Ma, Yin Liu, Lin Jiang, Xiaoyu Zhu, Xin Hu, Zhi Ming Shao, Daniel G. Stover

المصدر: Cell Research

مصطلحات موضوعية: Adult, Oncology, medicine.medical_specialty, Paclitaxel, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Population, Triple Negative Breast Neoplasms, Biology, Article, Targeted therapy, Capecitabine, 03 medical and health sciences, Breast cancer, Targeted therapies, 0302 clinical medicine, Albumins, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Biomarkers, Tumor, medicine, Clinical endpoint, Humans, Molecular Targeted Therapy, Prospective Studies, RNA, Messenger, Precision Medicine, education, Molecular Biology, Triple-negative breast cancer, Aged, 030304 developmental biology, 0303 health sciences, education.field_of_study, High-Throughput Nucleotide Sequencing, Cell Biology, Middle Aged, medicine.disease, Antineoplastic Agents, Phytogenic, Immunohistochemistry, Subtyping, Treatment Outcome, 030220 oncology & carcinogenesis, PARP inhibitor, Female, Follow-Up Studies, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e381f58508e979cabe934861fb9f9e4fTest
https://doi.org/10.1038/s41422-020-0375-9Test

المؤلفون: Lora J. Kasselman, Steven E. Carsons, Allison B. Reiss, Heather A. Renna, Hirra A Arain, Joshua DeLeon, Juan Zhen, Michelle Petri, Iryna Voloshyna

المصدر: Medicina
Volume 55
Issue 9
Medicina; Volume 55; Issue 9; Pages: 514
Medicina, Vol 55, Iss 9, p 514 (2019)

مصطلحات موضوعية: Male, Medicine (General), Atorvastatin, Gene Expression, 030204 cardiovascular system & hematology, Pharmacology, Mixed Function Oxygenases, chemistry.chemical_compound, Plasma, 0302 clinical medicine, immune system diseases, Lupus Erythematosus, Systemic, skin and connective tissue diseases, ATP Binding Cassette Transporter, Subfamily G, Member 1, Liver X Receptors, 0303 health sciences, Systemic lupus erythematosus, biology, General Medicine, 3. Good health, Cholesterol, ABCG1, Disease Progression, Female, lipids (amino acids, peptides, and proteins), medicine.drug, ATP Binding Cassette Transporter 1, Adult, Statin, medicine.drug_class, macrophage, Article, 03 medical and health sciences, R5-920, lupus, atherosclerosis, cholesterol transport, statin, medicine, Humans, RNA, Messenger, cardiovascular diseases, Scavenger receptor, Liver X receptor, 030304 developmental biology, business.industry, Macrophages, medicine.disease, Lipid Metabolism, PPAR gamma, chemistry, LDL receptor, biology.protein, ATP-Binding Cassette Transporters, Hydroxymethylglutaryl-CoA Reductase Inhibitors, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa375dff7dac95617cd5d6ea98954556Test

المؤلفون: Muhammad Ahmed, Waleed H. Malki, Imran Shahid, Ashraf N. Abdalla, Mohammad Akbar Hossain, Amal Qattan

المصدر: Molecules
Volume 25
Issue 20
Molecules, Vol 25, Iss 4606, p 4606 (2020)

مصطلحات موضوعية: cyclin D1, Pharmaceutical Science, Pyridinium Compounds, Analytical Chemistry, chemistry.chemical_compound, 0302 clinical medicine, Drug Discovery, 0303 health sciences, biology, Cell Cycle, Indolizines, Middle Aged, Chemistry (miscellaneous), 030220 oncology & carcinogenesis, MCF-7 Cells, Molecular Medicine, medicine.drug, Adult, CDK2, kinase activity profiling, Breast Neoplasms, Hsp90, Article, Cell Line, Cyclic N-Oxides, lcsh:QD241-441, 03 medical and health sciences, Cyclin D1, lcsh:Organic chemistry, Cyclin-dependent kinase, medicine, Humans, HSP90 Heat-Shock Proteins, Physical and Theoretical Chemistry, Dinaciclib, Kinase activity, PI3K/AKT/mTOR pathway, 030304 developmental biology, Aged, business.industry, Phospholipase C gamma, Organic Chemistry, Cyclin-dependent kinase 2, Cyclin-Dependent Kinase 2, Vascular Endothelial Growth Factor Receptor-2, VEGFR-2, Focal Adhesion Kinase 2, chemistry, Focal Adhesion Kinase 1, Cancer cell, biology.protein, Cancer research, luminal-A breast cancer, business, Tamoxifen

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e32cc0819b70b9392948725ef2611ee6Test

المؤلفون: Julius O. Nyalwidhe, Peter Arvan, Cate Speake, Jerry L. Nadler, Carla J. Greenbaum, Margaret A. Morris, Henry T. Bahnson, Farooq Syed, Emily K. Sims, Leena Haataja, Carmella Evans-Molina, Raghavendra G. Mirmira, Teresa L. Mastracci

المصدر: Transl Res

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, endocrine system, endocrine system diseases, medicine.medical_treatment, Prohormone, Prohormone convertase, 030209 endocrinology & metabolism, Article, Proinflammatory cytokine, 03 medical and health sciences, Islets of Langerhans, Young Adult, 0302 clinical medicine, Physiology (medical), Internal medicine, medicine, Humans, 030304 developmental biology, Proinsulin, Laser capture microdissection, Inflammation, 0303 health sciences, Type 1 diabetes, geography, geography.geographical_feature_category, biology, Chemistry, Insulin, Biochemistry (medical), Public Health, Environmental and Occupational Health, nutritional and metabolic diseases, General Medicine, Middle Aged, medicine.disease, Islet, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 1, Carboxypeptidase E, 030220 oncology & carcinogenesis, biology.protein, Female, Immunostaining, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8159a52f5b5b2ee720dc511f52be746aTest
https://pubmed.ncbi.nlm.nih.gov/31442418Test

المؤلفون: Anne M. Murphy, Kimberly Y. Lin, Anna Axelsson Raja, Ling Shi, Lubna Choudhury, Alexandre C. Pereira, Luisa Mestroni, Steven D. Colan, Gregory D. Lewis, Eugene Braunwald, Charles E. Canter, E Kevin Hall, John J.V. McMurray, Jason R Becker, Mark W. Russell, Harry M. Lever, Carolyn Y. Ho, Elfriede Pahl, Matthew T. Wheeler, John L. Jefferies, Sharlene M. Day, Jose D. Vargas, Matthew R.G. Taylor, Richard G. Bach, Amit R. Patel, Anjali T. Owens, Scott D. Solomon, Allison L. Cirino, Henning Bundgaard, Joseph W. Rossano, Renee Margossian, Lee Benson, Calum A. MacRae, Kenneth G. Zahka, John Orav

المصدر: Circ Heart Fail

مصطلحات موضوعية: Male, Time Factors, Denmark, hypertrophic, 030204 cardiovascular system & hematology, Gene mutation, law.invention, 0302 clinical medicine, Randomized controlled trial, law, Child, 0303 health sciences, Hypertrophic cardiomyopathy, Middle Aged, Disease evolution, Phenotype, Treatment Outcome, Valsartan, Baseline characteristics, Cohort, Cardiology, Disease Progression, Female, Cardiology and Cardiovascular Medicine, Brazil, medicine.drug, Adult, Sarcomeres, medicine.medical_specialty, Canada, Adolescent, Article, 03 medical and health sciences, Young Adult, Double-Blind Method, Internal medicine, medicine, Humans, Genetic Predisposition to Disease, cardiovascular diseases, 030304 developmental biology, business.industry, angiotension receptor blocker, Recovery of Function, Cardiomyopathy, Hypertrophic, medicine.disease, United States, randomized controlled trial, Mutation, business, cardiomyopathy, Angiotensin II Type 1 Receptor Blockers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34aac896d7cae681f5f1bce73977c50fTest
https://pubmed.ncbi.nlm.nih.gov/31813281Test

المؤلفون: Sang-Yeob Kim, Min-Hee Ryu, Yoon-Koo Kang, Chan Young Ock, Yeon-Mi Ryu, Changhoon Yoo, Jihun Kim

المصدر: British Journal of Cancer

مصطلحات موضوعية: Male, Cancer Research, LAG3, Pyridines, Programmed Cell Death 1 Receptor, Angiogenesis Inhibitors, Gastroenterology, Tyrosine-kinase inhibitor, B7-H1 Antigen, chemistry.chemical_compound, 0302 clinical medicine, Sunitinib, Tumor Microenvironment, Receptors, Immunologic, Hepatitis A Virus Cellular Receptor 2, 0303 health sciences, biology, Neovascularization, Pathologic, CD68, Sarcoma, Middle Aged, Gene Expression Regulation, Neoplastic, Oncology, 030220 oncology & carcinogenesis, Imatinib Mesylate, Female, RNA Interference, medicine.drug, Adult, Cancer microenvironment, medicine.medical_specialty, medicine.drug_class, Gastrointestinal Stromal Tumors, CD3, Article, 03 medical and health sciences, TIGIT, Internal medicine, Regorafenib, medicine, Humans, Protein Kinase Inhibitors, 030304 developmental biology, Aged, Neoplasm Staging, business.industry, Phenylurea Compounds, medicine.disease, chemistry, biology.protein, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa95100df713e2bd6cef9b043c2a9383Test
https://pubmed.ncbi.nlm.nih.gov/31607749Test

المؤلفون: M. Ross Bullock, Gregory E. Conner, Juan Pablo de Rivero Vaccari, W. Dalton Dietrich, Oliver Umland, Robert W. Keane, Nadine Kerr

المصدر: Cells
Volume 8
Issue 1

مصطلحات موضوعية: Adult, Male, Pathology, medicine.medical_specialty, Adolescent, Traumatic brain injury, Inflammasomes, Caspase 1, caspase-1, Inflammation, Lung injury, Article, 03 medical and health sciences, Young Adult, 0302 clinical medicine, inflammasome, Brain Injuries, Traumatic, Medicine, Humans, Lung, 030304 developmental biology, Aged, Aged, 80 and over, 0303 health sciences, business.industry, pyroptosis, Pyroptosis, Endothelial Cells, Inflammasome, General Medicine, Extracellular vesicle, Lung Injury, Middle Aged, medicine.disease, brain injury, 3. Good health, CARD Signaling Adaptor Proteins, medicine.anatomical_structure, ROC Curve, inflammation, Female, medicine.symptom, business, extracellular vesicles, 030217 neurology & neurosurgery, Biomarkers, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423bcfe44e4e50c4ae80540a91e750dcTest

المؤلفون: Thomas Conrad, Thanh Bach, Jessie K. Kennedy, Armando E. Gonzalez, Larissa V. Stebounova, Hector H. Garcia, Kiran Gajurel, Daryl J. Murry, Greg Deye, Patricia L. Winokur, Walt Jones, Denice M. Hodgson-Zingman, John R. Horton, Ellen E. Codd, Effie Y.H. Nomicos, Guohua An, Robert H. Gilman, Dilek Ince

مصطلحات موضوعية: Male, double blind procedure, ultra performance liquid chromatography, limit of quantitation, Clinical pharmacokinetics, diarrhea, volume of distribution, Pharmacology, 0302 clinical medicine, Elimination rate constant, aspartate aminotransferase, Pharmacology (medical), Volume of distribution, 0303 health sciences, drug dose regimen, adult, Healthy Volunteers, medicine.drug_formulation_ingredient, priority journal, oxfendazole glucuronide, First-in-human study, drug exposure, Biological Availability, bicarbonate, urinary excretion, Clinical Therapeutics, purl.org/pe-repo/ocde/ford#3.03.08 [https], Article, 03 medical and health sciences, Pharmacokinetics, Taenia solium, activated partial thromboplastin time, Humans, neutropenia, no-observed-adverse-effect level, purl.org/pe-repo/ocde/ford#3.01.05 [https], human, normal human, arthralgia, liquid chromatography-mass spectrometry, elimination half-life, Dose-Response Relationship, Drug, 030306 microbiology, maximum plasma concentration, leukopenia, drug bioavailability, major clinical study, drug metabolism, flatulence, plasma half life, time to maximum plasma concentration, randomized controlled trial, drug solubility, Benzimidazoles, drug metabolite, drug tolerability, drug safety, phase 1 clinical trial, Administration, Oral, Anthelmintic agent, Area under the curve, single drug dose, Middle Aged, sore throat, unclassified drug, Infectious Diseases, female, Tolerability, leukocytosis, Female, eosinophilia, medicine.drug, Half-Life, bicarbonate blood level, Adult, oxfendazole, Oxfendazole, pharmacokinetic parameters, Adolescent, side effect, area under the curve, 030231 tropical medicine, oxfendazole sulfate, Young Adult, Double-Blind Method, male, first in human study, medicine, controlled study, fenbendazole, viral gastroenteritis, business.industry, Cysticercosis, oxfendazole sulfone, renal clearance, intestine absorption, elimination rate constant, Fenbendazole, PR interval, business, drug dose escalation, plasma concentration-time curve

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2f203b7c43ba03e0341087ee72baa34Test
https://hdl.handle.net/20.500.12866/7396Test

المؤلفون: Bogusz Trojanowicz, Roman Fiedler, Susann Wildgrube, Christoph Schäfer, C. Ulrich, Matthias Girndt, Silke Markau, Leonie Kneser, Sylvia Fick, Eric Seibert

المصدر: Toxins
Toxins, Vol 12, Iss 675, p 675 (2020)
Volume 12
Issue 11

مصطلحات موضوعية: Male, Inflammasomes, Health, Toxicology and Mutagenesis, medicine.medical_treatment, Interleukin-1beta, caspase-1, lcsh:Medicine, Kidney, Toxicology, Monocytes, Body Mass Index, 0302 clinical medicine, Medicine, 0303 health sciences, education.field_of_study, hemodialysis, Pyroptosis, Inflammasome, Middle Aged, Female, Hemodialysis, medicine.symptom, medicine.drug, Adult, medicine.medical_specialty, hypertension, Population, Caspase 1, Renal function, Inflammation, Article, 03 medical and health sciences, Renal Dialysis, Internal medicine, NLR Family, Pyrin Domain-Containing 3 Protein, Diabetes Mellitus, Humans, education, Aged, 030304 developmental biology, business.industry, lcsh:R, Overweight, Blood pressure, Endocrinology, inflammation, Kidney Failure, Chronic, business, 030215 immunology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa74e2918dd28e9bf1de9751308a9f22Test
https://doi.org/10.3390/toxins12110675Test

المؤلفون: Benigno C. Valdez, Borje S. Andersson, Yan Liu, Bouthaina S. Dabaja, Qaiser Bashir, Peter F. Thall, Fredrick B. Hagemeister, Yasuhiro Oki, Alison M. Gulbis, Muzaffar H. Qazilbash, Chitra Hosing, Yago Nieto, Elizabeth J. Shpall, Sairah Ahmed, Nina Shah, Michelle A. Fanale, Paolo Anderlini, Roy B. Jones, Chelsea C. Pinnix, Uday R. Popat, Amin M. Alousi, Richard E. Champlin

المصدر: Biology of Blood and Marrow Transplantation. 21(11):1914-1920

مصطلحات موضوعية: Male, Melphalan, Oncology, Transplantation Conditioning, Lymphoma, medicine.medical_treatment, Pharmacology, Hydroxamic Acids, Deoxycytidine, 0302 clinical medicine, Recurrence, hemic and lymphatic diseases, Antineoplastic Combined Chemotherapy Protocols, High-dose chemotherapy, Refractory Diffuse Large B-Cell Lymphoma, Vorinostat, 0303 health sciences, Hematopoietic Stem Cell Transplantation, Hematology, Middle Aged, Hodgkin Disease, 3. Good health, 030220 oncology & carcinogenesis, Female, Rituximab, Lymphoma, Large B-Cell, Diffuse, medicine.drug, Adult, medicine.medical_specialty, Adolescent, Lymphoma, T-Cell, Transplantation, Autologous, Drug Administration Schedule, Article, 03 medical and health sciences, Phase 1 trial, Autologous stem-cell transplantation, Internal medicine, medicine, Humans, Busulfan, Aged, 030304 developmental biology, Chemotherapy, Transplantation, business.industry, medicine.disease, Survival Analysis, Gemcitabine, business, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b5215a45cc55252baf565d3d5217bfdTest