نتائج البحث

1

Activity of PD-1 blockade with nivolumab among patients with recurrent atypical/anaplastic meningioma: phase II trial results

المصدر: Neuro-Oncology. 24:101-113

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::e5b61609555c87e43ca6dd9087c056b2Test
https://doi.org/10.1093/neuonc/noab118Test

2

ELF3 activated by a superenhancer and an autoregulatory feedback loop is required for high-level HLA-C expression on extravillous trophoblasts

المؤلفون: Sarika Kshirsagar, Sai Ma, Qin Li, Jack L. Strominger, Jason D. Buenrostro, Fang Wang, Tamara Tilburgs, Torsten B. Meissner, Ziming Du, Motonari Uesugi

المصدر: Proceedings of the National Academy of Sciences of the United States of America

مصطلحات موضوعية: 0301 basic medicine, Small interfering RNA, Indoles, HLA-C, superenhancer, Adamantane, MED1, Mediator Complex Subunit 1, 0302 clinical medicine, Immunology and Inflammation, autoregulatory feedback loop, Pregnancy, RNA, Small Interfering, Promoter Regions, Genetic, Feedback, Physiological, Multidisciplinary, Mediator Complex, Chemistry, Gene Expression Regulation, Developmental, Azepines, Biological Sciences, Cell biology, Chromatin, Trophoblasts, DNA-Binding Proteins, Enhancer Elements, Genetic, 030220 oncology & carcinogenesis, embryonic structures, Abortion, Legal, Female, Protein Binding, Signal Transduction, Primary Cell Culture, Regulatory Factor X Transcription Factors, HLA-C Antigens, Cell Line, 03 medical and health sciences, Coactivator, Humans, (+)-JQ1, Gene, Transcription factor, Proto-Oncogene Proteins c-ets, Promoter, Triazoles, ELF3, Pregnancy Trimester, First, 030104 developmental biology, HLA-B Antigens, Chromatin immunoprecipitation, Immunity, Maternally-Acquired, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2058abbf01ec1155e3a4b0152625cd7cTest
https://pubmed.ncbi.nlm.nih.gov/33622787Test

3

Mismatch Repair Deficiency in High-Grade Meningioma: A Rare but Recurrent Event Associated With Dramatic Immune Activation and Clinical Response to PD-1 Blockade

المؤلفون: Ian F. Dunn, Keith L. Ligon, Sandro Santagata, Adrian M. Dubuc, Jia-Ren Lin, Michael B. Sisti, David A. Reardon, Julia A. Elvin, Eric Allan Severson, Shakti H. Ramkissoon, Matthew D. Ducar, Brenda Acevedo, Lais Cabrera, Patrick Y. Wen, Peter K. Sorger, Renato Umeton, Ziming Du, Peter Canoll, Mehdi Touat

المصدر: JCO Precision Oncology. :1-12

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5824eca150d178f2dadc86f94bcc4251Test
https://doi.org/10.1200/po.18.00190Test

4

Multiplexed immunofluorescence reveals potential PD-1/PD-L1 pathway vulnerabilities in craniopharyngioma

المؤلفون: Peter E. Manley, Ziming Du, Mark W. Kieran, Sandro Santagata, Peter K. Sorger, Rumana Rashid, Jia-Ren Lin, Todd C. Hankinson, Nicholas K. Foreman, Andrew M. Donson, David A. Reardon, Shannon Coy

المصدر: Neuro-Oncology. 20:1101-1112

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda80fd071a5d98475a6f041fe3489b7Test
https://doi.org/10.1093/neuonc/noy035Test

5

Diagnostic and Prognostic Characteristics of Circulating Free DNA Methylation Detected by the Electrochemical Method in Malignant Tumors

المؤلفون: Ting Wang, Xiao-Min Liu, Yan-Hong Li, Jian Yong Shao, Li-Yue Sun, Yu-Ying Liu, Ziming Du

المصدر: Cancers
Volume 13
Issue 4
Cancers, Vol 13, Iss 664, p 664 (2021)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9778bb3d753ffbc76f7ba2ff4fa6270Test
https://doi.org/10.3390/cancers13040664Test

6

Decreased FOXJ1 expression and its ciliogenesis programme in aggressive ependymoma and choroid plexus tumours

المؤلفون: Parker H. Merrill, Ziming Du, Malak Abedalthagafi, Michael P Wu, Terri Woo, Shu Hsien Sheu, Keith L. Ligon, Shelley Hurwitz, Sandro Santagata

المصدر: The Journal of Pathology. 238:584-597

مصطلحات موضوعية: 0301 basic medicine, Ependymoma, Pathology, medicine.medical_specialty, Cellular differentiation, Cilium, Subventricular zone, Biology, medicine.disease, Pathology and Forensic Medicine, 03 medical and health sciences, 030104 developmental biology, medicine.anatomical_structure, Ciliogenesis, medicine, Choroid plexus, Choroid Plexus Neoplasm, Ependyma

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::84b840fefd07c680152f630b89e4958cTest
https://doi.org/10.1002/path.4682Test

7

Meningioma transcription factors link cell lineage with systemic metabolic cues

المؤلفون: Lynette M. Sholl, Malak Abedalthagafi, Ziming Du, Josh Francis, Lars Geffers, Parker H. Merrill, Juliann Chmielecki, Sandro Santagata, Brian M. Alexander, Ayal A. Aizer, Ryan Brewster

المصدر: Neuro-Oncology

مصطلحات موضوعية: 0301 basic medicine, Leptin, Male, Cancer Research, Receptors, Prostaglandin, Apoptosis, Cohort Studies, Mice, 0302 clinical medicine, Meningeal Neoplasms, Tumor Cells, Cultured, Receptors, Immunologic, Cell Cycle, Intracellular Signaling Peptides and Proteins, Nuclear Proteins, Cell cycle, Middle Aged, Prognosis, Survival Rate, Oncology, 030220 oncology & carcinogenesis, Basic and Translational Investigations, Receptors, Leptin, Female, Meningioma, Brain tumor, Biology, 03 medical and health sciences, Coactivator, medicine, otorhinolaryngologic diseases, Biomarkers, Tumor, Animals, Humans, Cell Lineage, Obesity, Transcription factor, neoplasms, Cell Proliferation, Homeodomain Proteins, Leptin receptor, medicine.disease, Xenograft Model Antitumor Assays, nervous system diseases, Gene expression profiling, 030104 developmental biology, Tissue Array Analysis, Case-Control Studies, Cancer research, Homeobox, Neurology (clinical), Protein Tyrosine Phosphatases, Follow-Up Studies, Transcription Factors

وصف الملف: application/pdf; text/html

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb68d3635c4d2230436158ba9ff6482eTest
https://europepmc.org/articles/PMC6120365Test/

8

Osteoglycin promotes meningioma development through downregulation of NF2 and activation of mTOR signaling

المؤلفون: Ziming Du, Sandro Santagata, Nathalie Y. R. Agar, Malak Abedalthagafi, Ian F. Dunn, Yu Mei, Wenya Linda Bi, Noah F. Greenwald, Changchen Hu, Gavin P. Dunn

المصدر: Cell Communication and Signaling : CCS
Cell Communication and Signaling, Vol 15, Iss 1, Pp 1-11 (2017)

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, lcsh:Medicine, Down-Regulation, mTORC1, Biology, medicine.disease_cause, Biochemistry, AKT inhibitor, Meningioma, 03 medical and health sciences, Internal medicine, Cell Line, Tumor, medicine, otorhinolaryngologic diseases, Autophagy, Meningeal Neoplasms, Humans, RNA, Messenger, lcsh:QH573-671, Molecular Biology, Protein kinase B, neoplasms, PI3K/AKT/mTOR pathway, Cell Proliferation, Neurofibromin 2, Oncogene, Cell growth, lcsh:Cytology, Osteoglycin, Research, TOR Serine-Threonine Kinases, lcsh:R, Cell Biology, Cell cycle, medicine.disease, Mammalian target of rapamycin complex 1, 3. Good health, nervous system diseases, Neurofibromatosis type 2, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Endocrinology, Cancer research, Intercellular Signaling Peptides and Proteins, Carcinogenesis, Proto-Oncogene Proteins c-akt, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6326fe43fb6086ccb9d7c8b1753b87cbTest
http://europepmc.org/articles/PMC5604305Test

9

Distinct patterns of primary and motile cilia in Rathke's cleft cysts and craniopharyngioma subtypes

المؤلفون: Shu Hsien Sheu, Terri Woo, Shannon Coy, Mark W. Kieran, Fausto J. Rodriguez, Sandro Santagata, Ziming Du

المصدر: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 29(12)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a2482240a17b2e4966e275295c260fTest
https://pubmed.ncbi.nlm.nih.gov/27562488Test

10

Increased expression of programmed death ligand 1 (PD-L1) in human pituitary tumors

المؤلفون: Edward R. Laws, Sandro Santagata, Gordon J. Freeman, David A. Reardon, Yu Mei, Nathalie Y. R. Agar, Ziming Du, Ian F. Dunn, Whitney W. Woodmansee, Gavin P. Dunn, Wenya Linda Bi, Peter E. Fecci, Noah F. Greenwald, Ursula B. Kaiser

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, Oncology, Adenoma, PD-L1, medicine.medical_specialty, Pathology, medicine.medical_treatment, Brain tumor, Gene Expression, pituitary adenoma, B7-H1 Antigen, 03 medical and health sciences, 0302 clinical medicine, Pituitary adenoma, Internal medicine, checkpoint inhibition, medicine, Biomarkers, Tumor, Humans, Pituitary Neoplasms, RNA, Messenger, RNAscope, Tumor-infiltrating lymphocytes, business.industry, Gene Expression Profiling, Pituitary tumors, Cancer, Computational Biology, Immunotherapy, medicine.disease, Immunohistochemistry, Immune checkpoint, 030104 developmental biology, 030220 oncology & carcinogenesis, immunotherapy, business, Checkpoint Blockade Immunotherapy, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9e091d1f5d7c70bf1727ce623bf2832Test
https://pubmed.ncbi.nlm.nih.gov/27655724Test

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