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المؤلفون: Michel Salzet, Alice Capuz, Mélanie Rose, Antonella Raffo-Romero, Tsukasa Hara, Isabelle Fournier, Rinaldo van Meel, Franck Rodet, Marie Duhamel
المصدر: Journal of Biotechnology. 282:80-85
مصطلحات موضوعية: 0301 basic medicine, endocrine system, medicine.medical_treatment, Bioengineering, Context (language use), Proprotein convertase 1, Applied Microbiology and Biotechnology, Cell therapy, 03 medical and health sciences, 0302 clinical medicine, Neoplasms, medicine, Animals, Humans, Secretion, Chemistry, Macrophages, TLR9, General Medicine, Immunotherapy, Toll-Like Receptor 4, Protein Transport, 030104 developmental biology, Proprotein Convertase 1, Toll-Like Receptor 9, 030220 oncology & carcinogenesis, TLR4, Cancer research, Signal transduction, Signal Transduction, Biotechnology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30529219cee4d50fea7a44dfca71393cTest
https://doi.org/10.1016/j.jbiotec.2018.07.002Test -
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المؤلفون: Vasudevan Seshadri, Rucha D. Sarwade, Shardul D. Kulkarni, Abdul Khalique, Naina Gaikwad, Poonam R. Pandey
المصدر: Biochemical and Biophysical Research Communications. 526:618-625
مصطلحات موضوعية: 0301 basic medicine, endocrine system, medicine.medical_treatment, Protein Disulfide-Isomerases, Biophysics, Cytoplasmic Granules, Poly(A)-Binding Proteins, Biochemistry, Cell Line, Conserved sequence, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Biosynthesis, Poly(A)-binding protein, medicine, Animals, Insulin, Prohormone Convertases, RNA, Messenger, Molecular Biology, Messenger RNA, biology, Granule (cell biology), RNA, Cell Biology, Cell biology, Proprotein Convertase 2, 030104 developmental biology, Proprotein Convertase 1, chemistry, Protein Biosynthesis, 030220 oncology & carcinogenesis, biology.protein, 5' Untranslated Regions
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd5d9ca9aea1b52aaa89c0687f60821cTest
https://doi.org/10.1016/j.bbrc.2020.03.106Test -
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المؤلفون: Johanne Le Beyec Le Bihan, Muriel Coupaye, Jean-Claude Carel, Karine Clément, Patrick Tounian, Christine Poitou, Sophie Courbage, Jean-Marc Lacorte, A. Karsenty, Nathalie Lecomte, Julie Lemale, Gianpaolo De Filippo, Béatrice Dubern, Jean-Michel Oppert, Véronique Pelloux, Caroline Storey
المساهمون: Service de gastro-entérologie [CHU Trousseau], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Nutrition et obésités: approches systémiques (nutriomics) (UMR-S 1269 INSERM - Sorbonne Université), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Service de nutrition [CHU Pitié-Salpétrière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Pitié-Salpêtrière [AP-HP], Service de Biochimie Endocrinienne et Oncologie [CHU Pitié-Salpêtrière], CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Hôpital Robert Debré Paris, Hôpital Robert Debré, AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), Centre de recherche sur l'Inflammation (CRI (UMR_S_1149 / ERL_8252 / U1149)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Hôpital Louis Mourier - AP-HP [Colombes], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Gestionnaire, Hal Sorbonne Université, Nutrition et obésités: approches systémiques (UMR-S 1269) (Nutriomics), Service de Nutrition [CHU Pitié-Salpétrière], Institut E3M [CHU Pitié-Salpêtrière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Pitié-Salpêtrière [AP-HP], Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)
المصدر: Journal of Clinical Endocrinology and Metabolism
Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2021, ⟨10.1210/clinem/dgab404⟩
Journal of Clinical Endocrinology and Metabolism, 2021, ⟨10.1210/clinem/dgab404⟩مصطلحات موضوعية: 0301 basic medicine, Proband, Adult, Leptin, Male, medicine.medical_specialty, Heterozygote, Pro-Opiomelanocortin, Endocrinology, Diabetes and Metabolism, [SDV]Life Sciences [q-bio], Clinical Biochemistry, 030209 endocrinology & metabolism, Context (language use), leptin-melanocortin pathway, Biochemistry, Body Mass Index, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, severe early-onset obesity, Internal medicine, medicine, Endocrine system, Humans, Age of Onset, Child, Genotyping, Genetic Association Studies, Retrospective Studies, 2. Zero hunger, business.industry, Biochemistry (medical), Homozygote, Genetic Variation, medicine.disease, Phenotype, Obesity, Obesity, Morbid, [SDV] Life Sciences [q-bio], 030104 developmental biology, Proprotein Convertase 1, Receptors, Leptin, Female, business, Body mass index, Signal Transduction
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed3bc9ad643e77fb64e7d8036e68d4fTest
https://pubmed.ncbi.nlm.nih.gov/34097736Test -
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المؤلفون: Marianne Böni-Schnetzler, Marc Y. Donath, Daniel Konrad, Céline I. Laesser, Fabrizio C. Lucchini, Stephan Wueest, Marcela Borsigova, Werner Müller, Flurin Item
المصدر: Diabetes. 67:36-45
مصطلحات موضوعية: Leptin, Male, 0301 basic medicine, endocrine system, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Proprotein convertase 1, Biology, Eating, Mice, 03 medical and health sciences, Insulin resistance, Glucagon-Like Peptide 1, Internal medicine, Adipocytes, Cytokine Receptor gp130, Internal Medicine, medicine, Animals, Interleukin 6, Mice, Knockout, Glucose tolerance test, medicine.diagnostic_test, Interleukin-6, Reverse Transcriptase Polymerase Chain Reaction, Insulin, digestive, oral, and skin physiology, Glucose Tolerance Test, Glycoprotein 130, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Proprotein Convertase 1, Knockout mouse, biology.protein, Cytokines, hormones, hormone substitutes, and hormone antagonists, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c1bbf6b11bf029e775703e4e5241acTest
https://doi.org/10.2337/db17-0637Test -
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المؤلفون: Tao Xu, Peng Ge, Yuandong Yu, Yingpin Jiang, Longchao Xiang, Feng Ao, YunYan Tai, Fengjun Cao, Mingxing Li, Bingbing Yang, Yong Li, Bing Gu, Xuanbin Wang, Xiaojun Cai, Pindong Li, Xiongjie Yu
المصدر: Redox Biology, Vol 20, Iss, Pp 451-457 (2019)
Redox Biologyمصطلحات موضوعية: GSSG, Oxidized glutathione, 0301 basic medicine, Colorectal cancer, medicine.medical_treatment, Clinical Biochemistry, Apoptosis, TCA cycle, Tricarboxylic acid, Biochemistry, Metastasis, NADP, Nicotinamide adenine dinucleotide phosphate, Mice, 0302 clinical medicine, Mitochondrial pyruvate transport, STAT3, lcsh:QH301-705.5, lcsh:R5-920, biology, Chemistry, Mitochondria, Colon cancer, Gene Expression Regulation, Neoplastic, Proprotein Convertase 2, Cytokine, Proprotein Convertase 1, Colonic Neoplasms, Female, lcsh:Medicine (General), Oxidation-Reduction, Glycolysis, MPC1/2, Mitochondrial pyruvate carrier 1 and 2, Short Communication, Antineoplastic Agents, γH2AX, Histone H2A.X, Models, Biological, GSH, Reduced glutathione, Redox, Interferon-gamma, 03 medical and health sciences, Immune system, NADPH, Reduced nicotinamide adenine dinucleotide phosphate, Cell Line, Tumor, medicine, Animals, Pyruvates, STAT, Signal transducer and activator of transcription, Organic Chemistry, NAC, N-acetylcysteine NAC, Biological Transport, IFN-γ, Interferon-γ, medicine.disease, Mitochondrial pyruvate carriers, 030104 developmental biology, lcsh:Biology (General), Cancer cell, biology.protein, Cancer research, TCGA, The Cancer Genome Atlas, Interferon-γ, Reactive Oxygen Species, 030217 neurology & neurosurgery, ROS, Reactive oxygen species
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::853916c7adaad27b06c716f2dac6ffbcTest
http://www.sciencedirect.com/science/article/pii/S2213231718307389Test -
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المؤلفون: Austin J. Taylor, Yi-Chun Chen, C. Bruce Verchere
المصدر: Diabetes, Obesity and Metabolism. 20:64-76
مصطلحات موضوعية: 0301 basic medicine, endocrine system, endocrine system diseases, Amyloid, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Prohormone, Prohormone convertase, Enteroendocrine cell, Mixed Function Oxygenases, Islets of Langerhans, 03 medical and health sciences, Endocrinology, Insulin-Secreting Cells, Internal Medicine, medicine, Humans, Insulin, Proinsulin, geography, geography.geographical_feature_category, business.industry, Carboxypeptidase H, Proglucagon, Islet, Cell biology, Proprotein Convertase 2, 030104 developmental biology, Proprotein Convertase 1, Glucagon-Secreting Cells, Amidine-Lyases, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca561a9eb16f74f222230e91cce4eb3Test
https://doi.org/10.1111/dom.13401Test -
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المؤلفون: Iris Lindberg, Manita Shakya
المصدر: Endocr Rev
مصطلحات موضوعية: 0301 basic medicine, animal structures, Endocrinology, Diabetes and Metabolism, Mutant, Proprotein convertase 1, Review, 03 medical and health sciences, Mice, 0302 clinical medicine, Endocrinology, Human disease, Animals, Humans, Furin, Proprotein Convertase 5, biology, fungi, Proprotein convertase, Cell biology, Disease Models, Animal, 030104 developmental biology, 030220 oncology & carcinogenesis, Knockout mouse, biology.protein, Proprotein Convertases, Genome-Wide Association Study
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e5569c855498eb2084d38125b630ea5Test
https://pubmed.ncbi.nlm.nih.gov/33382413Test -
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المؤلفون: Yaron Tomer, Angela Lombardi
المصدر: Journal of Autoimmunity. 80:48-55
مصطلحات موضوعية: X-Box Binding Protein 1, 0301 basic medicine, endocrine system, medicine.medical_specialty, medicine.medical_treatment, Immunology, Proprotein convertase 2, Apoptosis, Proprotein convertase 1, Article, Taurochenodeoxycholic Acid, 03 medical and health sciences, Downregulation and upregulation, Insulin-Secreting Cells, Internal medicine, medicine, Humans, Insulin, Immunology and Allergy, Cells, Cultured, Proinsulin, biology, Endoplasmic reticulum, Interferon-alpha, Endoplasmic Reticulum Stress, Phenylbutyrates, Diabetes Mellitus, Type 1, Proprotein Convertase 2, 030104 developmental biology, Endocrinology, Proprotein Convertase 1, Unfolded protein response, biology.protein, Cytokines, Binding immunoglobulin protein, Transcription Factor CHOP
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a6789f874857b15982297d1b89ee240Test
https://doi.org/10.1016/j.jaut.2017.02.002Test -
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المؤلفون: Brian Y.H. Lam, Giles S.H. Yeo, John Tadross, Charles Pyke, Irene Cimino, Joseph Polex-Wolf, Debra Rimmington, Georgina K.C. Dowsett, Anthony P. Coll, Lotte Bjerre Knudsen
المساهمون: Lam, Brian [0000-0002-3638-9025], Tadross, John A [0000-0002-8424-1252], Cimino, Irene [0000-0003-1397-5408], Coll, Anthony [0000-0003-2594-7463], Yeo, Giles [0000-0001-8823-3615], Apollo - University of Cambridge Repository
المصدر: Molecular Metabolism, Vol 53, Iss, Pp 101240-(2021)
Molecular Metabolismمصطلحات موضوعية: 0301 basic medicine, Population, 030209 endocrinology & metabolism, Hindbrain, Therapeutics, Biology, Eating, Mice, 03 medical and health sciences, 0302 clinical medicine, Gene expression, Solitary Nucleus, medicine, Animals, Obesity, education, Receptor, Internal medicine, Molecular Biology, Neurons, education.field_of_study, Sequence Analysis, RNA, Area postrema, Nucleus tractus solitarius, Fasting, Feeding Behavior, Cell Biology, RC31-1245, Oligodendrocyte, Cell biology, Mice, Inbred C57BL, Rhombencephalon, Proprotein Convertase 2, 030104 developmental biology, medicine.anatomical_structure, Proprotein Convertase 1, nervous system, Original Article, Melanocortin, Nucleus
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::797a4e91f46dc581034b86f24f591316Test
https://doi.org/10.1016/j.molmet.2021.101240Test -
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المؤلفون: Estelle Colin, Régis Coutant, Dominique Bonneau, Stéphanie Rouleau, Natacha Bouhours-Nouet, Marine Tessarech, Lucie Pépin
المساهمون: Physiopathologie Cardiovasculaire et Mitochondriale (MITOVASC), Université d'Angers (UA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Néonatalogie, Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)-PRES Université Nantes Angers Le Mans (UNAM), PRES Université Nantes Angers Le Mans (UNAM)
المصدر: The Journal of clinical endocrinology & metabolism
The Journal of clinical endocrinology & metabolism, 2019, 104 (4), pp.985-993. ⟨10.1210/jc.2018-01854⟩مصطلحات موضوعية: Male, 0301 basic medicine, endocrine system, medicine.medical_specialty, Turkey, Endocrinology, Diabetes and Metabolism, [SDV]Life Sciences [q-bio], Clinical Biochemistry, Proprotein convertase 1, Consanguinity, Hypoglycemia, Endocrine System Diseases, Biochemistry, 03 medical and health sciences, Rare Diseases, 0302 clinical medicine, Endocrinology, Hypogonadotropic hypogonadism, 030225 pediatrics, Internal medicine, Central hypothyroidism, medicine, Humans, Obesity, business.industry, Homozygote, Biochemistry (medical), Exons, Micropenis, medicine.disease, 3. Good health, 030104 developmental biology, Proprotein Convertase 1, Codon, Nonsense, Child, Preschool, Mutation, Diabetes insipidus, business, Proinsulin, Postprandial Hypoglycemia
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d4d0b68cbee25311de9954f7f6868cTest
https://hal.univ-angers.fr/hal-02616944Test
