نتائج البحث - "PRR, Pattern-Recognition Receptor"

1

TNFSF15 Promotes Antimicrobial Pathways in Human Macrophages and These Are Modulated by TNFSF15 Disease-Risk Variants

المؤلفون: Matija Hedl, Clara Abraham, Rui Sun

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 249-272 (2021)

مصطلحات موضوعية: 0301 basic medicine, FADD, Fas-associated protein with death domain, MDP, muramyl dipeptide, DR3, death receptor 3, Mice, 0302 clinical medicine, ERK, extracellular signal-regulated kinase, Enterococcus faecalis, Cells, Cultured, Original Research, TNF, tumor necrosis factor, IBD, inflammatory bowel disease, TRADD, tumor necrosis factor receptor 1-associated death domain, Gastroenterology, MDM, monocyte-derived macrophages, TACE, tumor necrosis factor converting enzyme, LC3II, light chain 3-II, Autocrine Communication, TNFSF15, TNF superfamily member 15, Receptors, Pattern Recognition, 030211 gastroenterology & hepatology, Tumor necrosis factor alpha, Signal transduction, PI3K, phosphoinositide 3-kinase, Crohn’s Disease, TLR, Toll-like receptor, Signal Transduction, Tumor Necrosis Factor Ligand Superfamily Member 15, MALT1, mucosa-associated lymphoid tissue lymphoma translocation protein 1, Primary Cell Culture, NF-κB, nuclear factor-κB, PRR, pattern-recognition receptor, TRAF2, TNF receptor associated factor 2, Biology, NOD, nucleotide-binding oligomerization domain, RNS, reactive nitrogen species, 03 medical and health sciences, Paracrine signalling, ROS, reactive oxygen species, RIP, receptor-interacting protein kinase, PDK1, pyruvate dehydrogenase kinase 1, Paracrine Communication, Genetics, Escherichia coli, Animals, Humans, Genetic Predisposition to Disease, lcsh:RC799-869, NOS2, nitric oxide synthase 2, Autocrine signalling, Protein kinase A, Receptors, Tumor Necrosis Factor, Member 25, Death domain, Hepatology, NEMO, NF-κB essential modulator, Macrophages, NADPH, nicotinamide adenine dinucleotide phosphate, Inflammatory Bowel Diseases, IL, interleukin, 030104 developmental biology, BMDM, bone marrow–derived macrophage, siRNA, small interfering RNA, Cancer research, lcsh:Diseases of the digestive system. Gastroenterology, JNK, Janus kinase, Cytokine secretion, Pattern Recognition Receptors, Death receptor 3, MAPK, mitogen-activated protein kinase, AIEC, adherent invasive Escherichia coli

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb21b1a8b74b5bc07131da592a5389bdTest
https://doi.org/10.1016/j.jcmgh.2020.08.003Test

2

Fraxetin inhibits interleukin-1β-induced apoptosis, inflammation, and matrix degradation in chondrocytes and protects rat cartilage in vivo

المؤلفون: Bitao Ma, Di Zhuang, Qing Wang, Lilun Jin, Wenchang Feng, Liping Qin

المصدر: Saudi Pharmaceutical Journal, Vol 28, Iss 12, Pp 1499-1506 (2020)
Saudi Pharmaceutical Journal : SPJ

مصطلحات موضوعية: 0301 basic medicine, BSA, bovine albumin serum, PRR, pattern recognition receptor, DAMP, damage-associated molecular pattern, Pharmaceutical Science, ECL, enhanced chemiluminescence, Matrix metalloproteinase, Extracellular matrix, chemistry.chemical_compound, 0302 clinical medicine, TNF-α, tumour necrosis factor, Fraxetin, SDS-PAGE, sodium dodecyl sulfate–polyacrylamide gel electrophoresis, MIA, monosodium iodoacetate, TUNEL assay, HRP, horseradish peroxidase, Catabolism, MyD88, myeloid differentiation primary response 88, ECM, extracellular matrix, MMP, matrix metalloproteinase, medicine.anatomical_structure, IL-1β, OA, osteoarthritis, Original Article, NF, nuclear factor, TLR, Toll-like receptor, DAPI, 4,6-diamidino-2-phenylindole, IgG, immunoglobulin G, RIPA, radio-immunoprecipitation assay, SPF, specific pathogen free, 03 medical and health sciences, CCK-8, cell counting kit-8, IκBα, inhibitor of NF-κB-α, In vivo, Osteoarthritis, medicine, TLR4/MyD88/NF-κB signaling, 030203 arthritis & rheumatology, Pharmacology, Inflammation, Cartilage, lcsh:RM1-950, SD, Sprague-Dawley, Molecular biology, TdT, terminal deoxynucleotidyl transferase, IL, interleukin, 030104 developmental biology, lcsh:Therapeutics. Pharmacology, chemistry, Terminal deoxynucleotidyl transferase, Apoptosis, TUNEL, TdT dUTP nick-end labeling, H&E, hematoxylin and eosin, PBS, phosphate buffered saline, PMSF, phenylmethanesulphonyl fluoride, MRI, magnetic resonance imaging

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e983a5ffbb58806e56a84e82964e7f0Test
http://www.sciencedirect.com/science/article/pii/S1319016420302218Test

3

Regulatory roles of ginseng on inflammatory caspases, executioners of inflammasome activation

المؤلفون: Miyong Yun, Young-Su Yi

المصدر: Journal of Ginseng Research, Vol 44, Iss 3, Pp 373-385 (2020)
Journal of Ginseng Research

مصطلحات موضوعية: 0301 basic medicine, Research areas, CARD, C-terminal caspase recruit domain, PRR, Pattern-recognition receptor, Review, Pharmacology, PGE2, Prostaglandin E2, Inflammasome, FIIND, Functional-to-find domain, Ginseng, chemistry.chemical_compound, 0302 clinical medicine, RGE, Korean Red Ginseng, lcsh:Botany, ASC, Apoptosis-associated speck-like protein containing CARD, IL, Interleukin, PAMP, Pathogen-associated molecular pattern, PYD, N-terminal pyrin domain, LPS, Lipopolysaccharide, Caspase, biology, Effector, food and beverages, GSDMD, Gasdermin D, LRR, Leucine-rich repeat, lcsh:QK1-989, Ginsenoside, 030220 oncology & carcinogenesis, medicine.symptom, Biotechnology, medicine.drug, Inflammation, Biochemistry, Genetics and Molecular Biology (miscellaneous), NO, Nitric oxide, complex mixtures, 03 medical and health sciences, COX-2, Cyclooxygenase-2, Immune system, medicine, NACHT, Nucleotide-binding and oligomerization domain, NLR, Nucleotide-binding oligomerization domain-like receptor, business.industry, DAMP, Danger-associated molecular pattern, NF-κB, Nuclear factor-kappa B, AIM2, Absent in melanoma 2, 030104 developmental biology, Complementary and alternative medicine, chemistry, Inflammatory caspase, Caspase, Cysteine aspartate–specific protease, biology.protein, HIN, Hematopoietic interferon-inducible nuclear protein, business, ROS, Reactive oxygen species

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f329426609bf78cf66d558eb1ea7ae14Test
http://www.sciencedirect.com/science/article/pii/S1226845319302830Test

4

IL23 Promotes Antimicrobial Pathways in Human Macrophages, Which Are Reduced With the IBD-Protective IL23R R381Q Variant

المؤلفون: Rui Sun, Clara Abraham

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 4, Pp 673-697 (2020)
Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: 0301 basic medicine, Th, T-helper cell, Interleukin-23, 0302 clinical medicine, MDMs, monocyte-derived macrophages, Macrophage, Cells, Cultured, Original Research, GFP, green fluorescent protein, TNF, tumor necrosis factor, Janus kinase 2, IBD, inflammatory bowel disease, biology, Chemistry, TYK2, Tyrosine kinase 2, Gastroenterology, Nitric oxide synthase 2, PI3K, phosphatidylinositol 3-kinase, Cell biology, LC3II, light chain 3-II, STAT, signal transducer and activator of transcription, Interleukin 12, LPS, lipopolysaccharide, 030211 gastroenterology & hepatology, JAK, Janus kinase, Infection, NK, natural killer, Intracellular, Crohn’s Disease, PRR, pattern-recognition receptor, Cell Line, NOD, nucleotide-binding oligomerization domain, RNS, reactive nitrogen species, 03 medical and health sciences, Paracrine signalling, ROS, reactive oxygen species, Immune system, PDK1, pyruvate dehydrogenase kinase 1, Autophagy, Genetics, Humans, Point Mutation, Ulcerative Colitis, IFN, interferon, lcsh:RC799-869, NOS2, nitric oxide synthase 2, Autocrine signalling, Bacteria, Hepatology, Macrophages, Receptors, Interleukin, NADPH, nicotinamide adenine dinucleotide phosphate, Inflammatory Bowel Diseases, IL, interleukin, 030104 developmental biology, siRNA, small interfering RNA, biology.protein, lcsh:Diseases of the digestive system. Gastroenterology, AIEC, adherent invasive Escherichia coli