نتائج البحث - "MITOGEN-activated protein kinase phosphatases"

1

DUSP4 promotes the carcinogenesis of CCRCC via negative regulation of autophagic death

المؤلفون: Changyan Zhu, Xianyou Zeng, Xianxin Zhu

المصدر: Bioscience, Biotechnology, and Biochemistry. 85:1839-1845

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Carcinogenesis, Cell Survival, medicine.disease_cause, Applied Microbiology and Biotechnology, Biochemistry, Analytical Chemistry, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Autophagy, medicine, Humans, Gene silencing, Gene Silencing, Carcinoma, Renal Cell, Molecular Biology, Gene, Aged, Cell Death, Chemistry, Organic Chemistry, General Medicine, Middle Aged, medicine.disease, Kidney Neoplasms, Gene Expression Regulation, Neoplastic, Clear cell renal cell carcinoma, 030104 developmental biology, Cell culture, 030220 oncology & carcinogenesis, Cancer research, Dual-Specificity Phosphatases, Mitogen-Activated Protein Kinase Phosphatases, Autophagic death, Biotechnology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ccfd54d0d885e7206833a7bc6eab61Test
https://doi.org/10.1093/bbb/zbab111Test

2

GFAP alternative splicing regulates glioma cell-ECM interaction in a DUSP4-dependent manner

المؤلفون: Jessy V. van Asperen, Miriam E. van Strien, Emma J. van Bodegraven, Coen B J van Deursen, Oscar M. J. A. Stassen, Pierre A. Robe, Elly M. Hol, Jacqueline A. Sluijs

المساهمون: Cell-Matrix Interact. Cardiov. Tissue Reg.

المصدر: The FASEB Journal, 33(11), 12941-12959. FASEB

مصطلحات موضوعية: 0301 basic medicine, MAP Kinase Kinase 4, Biochemistry, Mitogen-Activated Protein Kinase Phosphatases/genetics, Extracellular matrix, 0302 clinical medicine, Phosphorylation, Intermediate filament, Cytoskeleton, Tumor, Glial fibrillary acidic protein, biology, Brain Neoplasms, Chemistry, cytoskeleton, Glioma, Gene Knockdown Techniques, Dual-Specificity Phosphatases, Glioma/metabolism, Biotechnology, intermediate filaments, extracellular matrix, Phosphatase, GFAP isoforms, Dual-Specificity Phosphatases/genetics, Cell Line, Focal adhesion, 03 medical and health sciences, glioblastoma multiforme, Cell Line, Tumor, Glial Fibrillary Acidic Protein, Genetics, medicine, Humans, Molecular Biology, Alternative splicing, Extracellular Matrix/metabolism, medicine.disease, Laminin/metabolism, Alternative Splicing, 030104 developmental biology, MAP Kinase Kinase 4/metabolism, Cancer research, biology.protein, Mitogen-Activated Protein Kinase Phosphatases, Laminin, Glial Fibrillary Acidic Protein/genetics, CRISPR-Cas Systems, 030217 neurology & neurosurgery, Brain Neoplasms/metabolism

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22f98a81dfc825cd528e08052a5e406fTest
https://research.tue.nl/en/publications/4b991fe4-0534-4fa6-95b6-61354ccf9ca8Test

3

DUSP16 promotes cancer chemoresistance through regulation of mitochondria-mediated cell death

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications

مصطلحات موضوعية: Male, 0301 basic medicine, Colorectal cancer, medicine.medical_treatment, General Physics and Astronomy, Apoptosis, Tumour biomarkers, Gene Knockout Techniques, Mice, 0302 clinical medicine, Neoplasms, bcl-2-Associated X Protein, Aged, 80 and over, Multidisciplinary, Middle Aged, Mitochondria, Cancer therapeutic resistance, Chemotherapy, Adjuvant, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, Dual-Specificity Phosphatases, Female, Adult, Programmed cell death, MAP Kinase Signaling System, Science, Antineoplastic Agents, Cell Fractionation, Disease-Free Survival, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Breast cancer, Cell Line, Tumor, Biomarkers, Tumor, medicine, Animals, Humans, Aged, Chemotherapy, business.industry, Cancer, General Chemistry, medicine.disease, Xenograft Model Antitumor Assays, 030104 developmental biology, Nasopharyngeal carcinoma, Drug Resistance, Neoplasm, Cancer cell, Cancer research, Mitogen-Activated Protein Kinase Phosphatases, Cisplatin, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc584b47087c28dbb44baabfd0779768Test
https://doaj.org/article/7cd1e1ed821d475f86d18b8927eabe0dTest

4

SETD8 potentiates constitutive ERK1/2 activation via epigenetically silencing DUSP10 expression in pancreatic cancer

المؤلفون: Xiaowu Xu, Shunrong Ji, Zheng Zhang, Qifeng Zhuo, Wensheng Liu, Zeng Ye, Yi Qin, Wenyan Xu, Xianjun Yu, Mengqi Liu, Guixiong Fan, Qiangsheng Hu

المصدر: Cancer Letters. 499:265-278

مصطلحات موضوعية: STAT3 Transcription Factor, 0301 basic medicine, Cancer Research, MAP Kinase Signaling System, Kaplan-Meier Estimate, Histones, Mice, 03 medical and health sciences, Pancreatectomy, 0302 clinical medicine, Cell Line, Tumor, Biomarkers, Tumor, Animals, Humans, Gene silencing, Gene Silencing, Epigenetics, Promoter Regions, Genetic, STAT3, Pancreas, Cell Proliferation, biology, Cell growth, Chemistry, Gene Expression Profiling, Promoter, Histone-Lysine N-Methyltransferase, DNA Methylation, Prognosis, Xenograft Model Antitumor Assays, Up-Regulation, Gene Expression Regulation, Neoplastic, Pancreatic Neoplasms, 030104 developmental biology, Oncology, Cell culture, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Dual-Specificity Phosphatases, Mitogen-Activated Protein Kinase Phosphatases, Phosphorylation, Chromatin immunoprecipitation, Carcinoma, Pancreatic Ductal

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510b8428592492f981d36b8533bc5fdcTest
https://doi.org/10.1016/j.canlet.2020.11.023Test

5

Dual specificity phosphatase 9: A novel binding partner cum substrate of proapoptotic serine protease HtrA2

المؤلفون: Snehal Pandav Mudrale, Kakoli Bose, Saujanya Acharya, Shubhankar Dutta

المصدر: Biochemical and Biophysical Research Communications. 533:607-612

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec46789d5d32728c9f8e7fb7e6d2205Test
https://doi.org/10.1016/j.bbrc.2020.09.062Test

6

MiR-450a-5p inhibits autophagy and enhances radiosensitivity by targeting dual-specificity phosphatase 10 in esophageal squamous cell carcinoma

المؤلفون: Yixuan Zhang, Hongcheng Zhu, Shu Liu, Xijuan Yao, Xinchen Sun, Tingting Chen, Xiaoke Di, Hui Chen, Dingyue Yu

المصدر: Cancer Letters. 483:114-126

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Radiosensitizer, Esophageal Neoplasms, p38 mitogen-activated protein kinases, Mice, Nude, Apoptosis, Biology, Radiation Tolerance, p38 Mitogen-Activated Protein Kinases, Mice, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Cell Line, Tumor, Radioresistance, microRNA, Autophagy, Animals, Humans, Radiosensitivity, Mice, Inbred BALB C, JNK Mitogen-Activated Protein Kinases, Xenograft Model Antitumor Assays, Gene Expression Regulation, Neoplastic, MicroRNAs, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Cancer research, Dual-Specificity Phosphatases, Mitogen-Activated Protein Kinase Phosphatases, Esophageal Squamous Cell Carcinoma, Signal transduction, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4455cf57ee96bbbf91fceb3e4bf6dd4Test
https://doi.org/10.1016/j.canlet.2020.01.037Test

7

CircDUSP16 promotes the tumorigenesis and invasion of gastric cancer by sponging miR-145-5p

المؤلفون: Yeqian Zhang, Gang Zhao, Site Yu, Zizhen Zhang, Jia Xu, Chao-Jie Wang

المصدر: Gastric Cancer

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Apoptosis, Growth, medicine.disease_cause, Pathogenesis, Mice, 0302 clinical medicine, circDUSP16, Invasion, Tumor Cells, Cultured, Medicine, Mice, Inbred BALB C, Gene knockdown, Gastroenterology, RNA-Binding Proteins, miR-145-5p, General Medicine, Prognosis, Gene Expression Regulation, Neoplastic, Oncology, 030220 oncology & carcinogenesis, Dual-Specificity Phosphatases, Female, Original Article, Mice, Nude, 03 medical and health sciences, Stomach Neoplasms, In vivo, Biomarkers, Tumor, Animals, Humans, Neoplasm Invasiveness, Viability assay, Cell Proliferation, business.industry, Cancer, RNA, Circular, medicine.disease, Xenograft Model Antitumor Assays, In vitro, MicroRNAs, 030104 developmental biology, Cancer research, Mitogen-Activated Protein Kinase Phosphatases, Ectopic expression, Gastric cancer, business, Carcinogenesis, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dc51da032fd9d8605b1d9f0e6e639f5Test
https://doi.org/10.1007/s10120-019-01018-7Test

8

DUSP22 suppresses prostate cancer proliferation by targeting the EGFR‐AR axis

المؤلفون: Hsiu-Ping Lin, Shauh-Der Yeh, Cheng-Wei Chang, Yu-Wen Su, Wen-Jye Lin, Tse-Hua Tan, Hui-Min Ho

المصدر: The FASEB Journal. 33:14653-14667

مصطلحات موضوعية: Male, 0301 basic medicine, Phosphatase, Biochemistry, Serine, Dephosphorylation, Mice, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Cell Line, Tumor, Dual-specificity phosphatase, Genetics, medicine, Animals, Humans, Phosphorylation, Tyrosine, Molecular Biology, Cell Proliferation, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, biology, Kinase, Chemistry, Prostatic Neoplasms, medicine.disease, ErbB Receptors, Mice, Inbred C57BL, 030104 developmental biology, Receptors, Androgen, Cancer research, biology.protein, Dual-Specificity Phosphatases, Mitogen-Activated Protein Kinase Phosphatases, 030217 neurology & neurosurgery, Protein Binding, Signal Transduction, Biotechnology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf6ed3e1b6ed025e887ebe11eab4192Test
https://doi.org/10.1096/fj.201802558rrTest

9

Role of dual-specificity protein phosphatase DUSP10/MKP-5 in pulmonary fibrosis

المؤلفون: Leonhard Binzenhöfer, Jose D. Herazo-Maya, Anton M. Bennett, Demosthenes Bouros, Guoying Yu, Farida Ahangari, Naftali Kaminski, Theodoros Karampitsakos, Nikos Xylourgidis, Argyrios Tzouvelekis, Kisuk Min, Vassilis Aidinis

المصدر: Am J Physiol Lung Cell Mol Physiol

مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, MAPK/ERK pathway, MAP Kinase Signaling System, Physiology, Pulmonary Fibrosis, p38 mitogen-activated protein kinases, Phosphatase, Protein tyrosine phosphatase, Transforming Growth Factor beta1, Bleomycin, Mice, 03 medical and health sciences, 0302 clinical medicine, Physiology (medical), Pulmonary fibrosis, medicine, Animals, Humans, Phosphorylation, Fibroblast, Protein kinase A, Mice, Knockout, Antibiotics, Antineoplastic, Kinase, Chemistry, Cell Biology, Fibroblasts, medicine.disease, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Dual-Specificity Phosphatases, Mitogen-Activated Protein Kinase Phosphatases, Female, Signal Transduction, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1dc353643461706c980e3c0b19008b9Test
https://doi.org/10.1152/ajplung.00264.2018Test

10

Activation of Dusp14 protects against osteoclast generation and bone loss by regulating AMPKα-dependent manner

المؤلفون: Danian Ma, Lei Hong, Jiangbo Ai

المصدر: Biochemical and Biophysical Research Communications. 519:445-452

مصطلحات موضوعية: Male, 0301 basic medicine, Osteoporosis, Biophysics, Gene Expression, Osteoclasts, Bone Marrow Cells, Mice, Transgenic, AMP-Activated Protein Kinases, Biochemistry, Bone resorption, 03 medical and health sciences, 0302 clinical medicine, Skeletal disorder, Osteoclast, medicine, Animals, Bone Resorption, Molecular Biology, Cells, Cultured, biology, Chemistry, Macrophage Colony-Stimulating Factor, Macrophages, RANK Ligand, Cell Biology, medicine.disease, Cell biology, Enzyme Activation, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, RANKL, 030220 oncology & carcinogenesis, Chronic inflammatory response, biology.protein, MAP kinase phosphatase, Dual-Specificity Phosphatases, Mitogen-Activated Protein Kinase Phosphatases, Signal transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1e312c50b530195d45cc3686b2a51ccTest
https://doi.org/10.1016/j.bbrc.2019.07.091Test

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