نتائج البحث - "Anti‐PD‐1 antibody"

1

Tislelizumab uniquely binds to the CC′ loop of PD‐1 with slow‐dissociated rate and complete PD‐L1 blockage

المؤلفون: Xinxin Cui, Bo Zhang, Yucheng Li, Hanzi Sun, Ye Liu, Yuan Hong, Mike Liu, Xiaomin Song, Yingcai Feng, Hongfu Wu, Qing Zhu, Yilu Zhang, Kang Li, Zhuo Li, Tong Zhang

المصدر: FEBS Open Bio, Vol 11, Iss 3, Pp 782-792 (2021)
FEBS Open Bio

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Protein Conformation, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Melanoma, Experimental, Mice, Transgenic, Antibodies, Monoclonal, Humanized, General Biochemistry, Genetics and Molecular Biology, Epitope, Mice, 03 medical and health sciences, Antineoplastic Agents, Immunological, 0302 clinical medicine, Protein Domains, Cancer immunotherapy, medicine, Animals, Humans, Surface plasmon resonance, Receptor, lcsh:QH301-705.5, Research Articles, Binding Sites, Chemistry, anti‐PD‐1 antibody, PD‐1, tislelizumab, Surface Plasmon Resonance, Ligand (biochemistry), Xenograft Model Antitumor Assays, Immune checkpoint, Cell biology, epitope mapping, 030104 developmental biology, Epitope mapping, lcsh:Biology (General), Mechanism of action, 030220 oncology & carcinogenesis, Mutation, medicine.symptom, BGB‐A317, Research Article, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372a66c9227616558eb3b872db5bcf28Test
https://doi.org/10.1002/2211-5463.13102Test

2

Association between serum level soluble programmed cell death ligand 1 and prognosis in patients with non‐small cell lung cancer treated with anti‐PD ‐1 antibody

المؤلفون: Yuji Matsumoto, Yuichiro Ohe, Hidehito Horinouchi, Ryota Shibaki, Shuji Murakami, Noboru Yamamoto, Yasushi Goto, Shintaro Kanda, Yutaka Fujiwara, Tatsuya Yoshida

المصدر: Thoracic Cancer

مصطلحات موضوعية: non‐small cell lung cancer, Adult, Male, 0301 basic medicine, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Lung Neoplasms, Multivariate analysis, soluble PD‐L1, Pembrolizumab, Antibodies, Monoclonal, Humanized, Gastroenterology, Programmed cell death ligand 1, 03 medical and health sciences, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Internal medicine, mental disorders, medicine, Humans, Anti‐PD‐1 antibody, In patient, Lung cancer, Aged, Aged, 80 and over, biology, business.industry, Hazard ratio, Original Articles, General Medicine, PD‐L1 TPS, Middle Aged, Prognosis, medicine.disease, Survival Analysis, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, biology.protein, Original Article, Female, Nivolumab, Antibody, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19fced2ae8c7ae9ecc4e68e52a492d5dTest
https://doi.org/10.1111/1759-7714.13721Test

3

Successful treatment with nivolumab in a patient with lung adenocarcinoma complicated by pulmonary aspergilloma

المؤلفون: Koji Kojima, Hisashi Saji, Hideki Marushima, Takeo Inoue, Eriko Koda, Naoki Furuya, Masamichi Mineshita, Kazutaka Kakinuma, Akihito Tsunoda, Kohei Nishida, Hajime Tsuruoka

المصدر: Thoracic Cancer
Thoracic Cancer, Vol 11, Iss 11, Pp 3391-3395 (2020)

مصطلحات موضوعية: non‐small cell lung cancer, 0301 basic medicine, Pulmonary and Respiratory Medicine, Oncology, medicine.medical_specialty, Case Report, Case Reports, lcsh:RC254-282, 03 medical and health sciences, 0302 clinical medicine, Immune system, Internal medicine, medicine, Anti‐PD‐1 antibody, In patient, pulmonary aspergilloma, nivolumab, Lung, business.industry, Chronic pulmonary aspergillosis, General Medicine, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, chronic infection, medicine.disease, respiratory tract diseases, Chronic infection, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Adenocarcinoma, Nivolumab, business, Aspergilloma

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e72ba8fae25e933c2493dee0a185a478Test
https://doi.org/10.1111/1759-7714.13662Test

4

A phase I study of toripalimab, an anti‐PD‐1 antibody, in patients with refractory malignant solid tumors

المؤلفون: Xiao-Li Wei, Chao Ren, Sheng Yao, Hongyun Zhao, Dong Sheng Zhang, Rui-Hua Xu, Fenghua Wang, Miao Zhen Qiu, Yang Zhang, Benyan Zou, Feng Wang, Huiyan Luo, Zhi Qiang Wang

المصدر: Cancer Communications, Vol 40, Iss 8, Pp 345-354 (2020)
Cancer Communications

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Esophageal Neoplasms, Programmed Cell Death 1 Receptor, efficacy, Gastroenterology, 0302 clinical medicine, Melanoma, toripalimab, biology, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Rash, Tongue Neoplasms, phase I study, Oncology, 030220 oncology & carcinogenesis, Toxicity, Carcinoma, Squamous Cell, Original Article, Female, Esophageal Squamous Cell Carcinoma, medicine.symptom, Antibody, pharmacokinetics, Adult, safety, medicine.medical_specialty, Adenocarcinoma, Antibodies, Monoclonal, Humanized, lcsh:RC254-282, 03 medical and health sciences, Refractory, Pharmacokinetics, Stomach Neoplasms, Internal medicine, medicine, pharmacodynamics, Humans, Adverse effect, business.industry, anti‐PD‐1 antibody, Cancer, Nasopharyngeal Neoplasms, Pharyngeal Neoplasms, Original Articles, medicine.disease, Pancreatic Neoplasms, 030104 developmental biology, Bile Duct Neoplasms, Pharmacodynamics, biology.protein, solid tumor, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cabe6aa8080fead097408c8cf0b04faTest
https://doaj.org/article/8ce01e25a806447a911986d71c98652aTest

5

Immunological effects of nivolumab immunotherapy in patients with oral cavity squamous cell carcinoma

المؤلفون: Kent Armeson, Hannah M. Knochelmann, Chrystal M. Paulos, Ying Xiong, David M. Neskey, M. Rita I. Young, Joshua D. Horton

المصدر: BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
BMC Cancer

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Male, 0301 basic medicine, Cancer Research, T cell, medicine.medical_treatment, CD8-Positive T-Lymphocytes, T-Lymphocytes, Regulatory, lcsh:RC254-282, 03 medical and health sciences, Antineoplastic Agents, Immunological, 0302 clinical medicine, Immune system, T-cell, Genetics, Humans, Medicine, Aged, biology, business.industry, Granzyme B, Anti-PD-1 antibody, FOXP3, Immunotherapy, CD8, Middle Aged, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, CD4, 3. Good health, Immune, Nivolumab, 030104 developmental biology, medicine.anatomical_structure, Oncology, Granzyme, 030220 oncology & carcinogenesis, Carcinoma, Squamous Cell, Cancer research, biology.protein, Female, Mouth Neoplasms, Interferon-γ, business, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c392816588bef0c85263e2eb6fea5b86Test
http://link.springer.com/article/10.1186/s12885-020-06726-3Test

6

Immunological features of a lung cancer patient achieving an objective response with anti‐programmed death‐1 blockade therapy

المؤلفون: Yukiko Kanetsuna, Mariko Takami, Shigetoshi Yoshida, Takahide Toyoda, Toshiko Kamata, Ichiro Yoshino, Hiroko Yoshizawa, Tetsuo Sato, Seiichi Nobuyama, Shinichiro Motohashi, Yuichiro Takeshita, Fumie Ihara

المصدر: Cancer Science

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb46d25c690760f3ec7ac0b81cd3468dTest
https://doi.org/10.1111/cas.14222Test

7

Combination Treatment of Topical Imiquimod Plus Anti-PD-1 Antibody Exerts Significantly Potent Antitumor Effect

المؤلفون: Ryota Tanaka, Manabu Fujimoto, Zhu Zhenjie, Yasuhiro Fujisawa, Kazumasa Oya, Noriko Kubota, Naoko Okiyama, Rei Watanabe, Akimasa Saito, Yuki Ichimura, Yosuke Ishitsuka, Yoshiyuki Nakamura, Hideaki Tahara

المصدر: Cancers; Volume 13; Issue 16; Pages: 3948
Cancers
Cancers, Vol 13, Iss 3948, p 3948 (2021)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d8344952f1ddc6f7f9bbac61f2f236Test

8

Immunogenic chemotherapy in two mouse colon cancer models

المؤلفون: Yoshitsugu Tajima, Takahito Taniura, Kazunari Ishitobi, Yuichi Iida, Hitoshi Kotani, Mamoru Harada

المصدر: Cancer Science

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, anti-PD-1 antibody, Colorectal cancer, medicine.medical_treatment, Mice, Nude, CD8-Positive T-Lymphocytes, chemotherapy, cytotoxic T lymphocytes, 03 medical and health sciences, Mice, 0302 clinical medicine, Immune system, Basic and Clinical Immunology, Cell Line, Tumor, Antineoplastic Combined Chemotherapy Protocols, medicine, Cytotoxic T cell, Animals, Cyclophosphamide, Mice, Inbred BALB C, biology, business.industry, Myeloid-Derived Suppressor Cells, anti‐PD‐1 antibody, Immunity, Cancer, General Medicine, Immunotherapy, medicine.disease, Immune checkpoint, Mice, Inbred C57BL, Oxaliplatin, Disease Models, Animal, 030104 developmental biology, Oncology, colon cancer, 030220 oncology & carcinogenesis, Colonic Neoplasms, Cancer research, biology.protein, Original Article, Fluorouracil, immunotherapy, Antibody, business, CD8, T-Lymphocytes, Cytotoxic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4841bfab377c2ff9a2f30489cf7a75abTest
https://pubmed.ncbi.nlm.nih.gov/32816355Test

9

Organizing pneumonia after thoracic radiotherapy followed by anti‐PD‐1 antibody treatment for patients with lung cancer: Three case reports

المؤلفون: Naoya Ishibashi, Masakuni Sakaguchi, Takuya Aizawa, Toshiya Maebayashi, Masahiro Okada

المصدر: Thoracic Cancer, Vol 10, Iss 6, Pp 1503-1507 (2019)
Thoracic Cancer

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7d8a4bfd1e057f556bbdaeb8ec249f7Test
https://doi.org/10.1111/1759-7714.13102Test

10

Malignant pleural effusion as a predictor of the efficacy of anti‐PD‐1 antibody in patients with non‐small cell lung cancer

المؤلفون: Hidehito Horinouchi, Ryota Shibaki, Shuji Murakami, Yasushi Goto, Noboru Yamamoto, Noriko Motoi, Yuji Matsumoto, Shintaro Kanda, Yuichiro Ohe, Yutaka Fujiwara, Yuki Shinno

المصدر: Thoracic Cancer, Vol 10, Iss 4, Pp 815-822 (2019)
Thoracic Cancer

مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, Adult, Male, non‐small cell lung cancer, medicine.medical_specialty, Lung Neoplasms, Pembrolizumab, Antibodies, Monoclonal, Humanized, Gastroenterology, lcsh:RC254-282, B7-H1 Antigen, 03 medical and health sciences, 0302 clinical medicine, Antineoplastic Agents, Immunological, Internal medicine, Carcinoma, Non-Small-Cell Lung, medicine, Malignant pleural effusion, Humans, Anti‐PD‐1 antibody, malignant pleural effusion, Lung cancer, Survival analysis, Aged, Retrospective Studies, Aged, 80 and over, nivolumab, business.industry, Hazard ratio, Cancer, General Medicine, Original Articles, Middle Aged, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Survival Analysis, Confidence interval, Pleural Effusion, Malignant, 030104 developmental biology, Treatment Outcome, Oncology, 030220 oncology & carcinogenesis, Female, Original Article, pembrolizumab, Nivolumab, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45fc6ab7e017ab4578ff1f909ace617bTest
https://doaj.org/article/ddbbd7d29cf64cc8a67c93f2f4831fa6Test

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