نتائج البحث

1

Neuropeptide S-initiated sequential cascade mediated by OX1, NK1, mGlu5 and CB1 receptors: a pivotal role in stress-induced analgesia

المؤلفون: Girolamo Calo, Remo Guerrini, Yu-Chun Chiu, Chia Chun Hor, Lih-Chu Chiou, Ming Tatt Lee, Hsin Jung Lee, Yu-Ting Chiu

المصدر: Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-15 (2020)
Journal of Biomedical Science

مصطلحات موضوعية: Male, 0301 basic medicine, Cannabinoid receptor, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, lcsh:Medicine, Substance P, Pharmacology, Mice, chemistry.chemical_compound, 0302 clinical medicine, Receptor, Cannabinoid, CB1, Neuropeptide S, Orexin Receptors, Pharmacology (medical), Chemistry, Glutamate receptor, Neuropeptide S, Orexin, Substance P, Metabotropic glutamate receptor, Endocannabinoid, Periaqueductal gray, General Medicine, CB1, Metabotropic Glutamate 5, Endocannabinoid system, Endocannabinoid, Metabotropic glutamate receptor, Orexin, Periaqueductal gray, Animals, Neuropeptides, Receptor, Metabotropic Glutamate 5, Stress, Psychological, Ventral Thalamic Nuclei, Analgesia, Receptor, Stress, NO, 03 medical and health sciences, mental disorders, Cannabinoid, Molecular Biology, Research, Biochemistry (medical), lcsh:R, Cell Biology, Blockade, 030104 developmental biology, nervous system, Psychological, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2431a8326753b1661e3a5d82baba6b65Test
https://doaj.org/article/53f537b86a584716bdf814fb935a0b18Test

2

Electrophysiological study of the response of ventral tegmental area non-dopaminergic neurons to nicotine after concurrent blockade of orexin receptor-2 and cannabinoid receptors-1

المؤلفون: Parham Reisi, Hojjatallah Alaei, Reza Fartootzadeh, Fatemeh Azizi

المصدر: Brain Research. 1719:176-182

مصطلحات موضوعية: Male, 0301 basic medicine, AM251, Nicotine, Cannabinoid receptor, Pyridines, medicine.medical_treatment, Pharmacology, Nucleus Accumbens, 03 medical and health sciences, 0302 clinical medicine, Piperidines, Orexin Receptors, mental disorders, medicine, Animals, Premovement neuronal activity, Rats, Wistar, Receptors, Cannabinoid, Molecular Biology, Neurons, Cannabinoids, Chemistry, musculoskeletal, neural, and ocular physiology, General Neuroscience, Ventral Tegmental Area, Isoquinolines, Orexin receptor, Rats, Orexin, Ventral tegmental area, 030104 developmental biology, medicine.anatomical_structure, nervous system, Conditioning, Operant, Pyrazoles, Orexin Receptor Antagonists, Neurology (clinical), Cannabinoid, psychological phenomena and processes, 030217 neurology & neurosurgery, Developmental Biology, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d00377478850b74cb5a89e90220fccaTest
https://doi.org/10.1016/j.brainres.2019.05.042Test

3

Identification and Characterization of Cannabidiol as an OX1R Antagonist by Computational and In Vitro Functional Validation

المؤلفون: Fabio Arturo Iannotti, Fabiana Piscitelli, Pietro Amodeo, Rosa Maria Vitale, Vincenzo Di Marzo, Ranjev Savopoulos, Luigia Cristino, Aniello Schiano Moriello, Royston A. Gray, Luciano De Petrocellis, Lea Tunisi

المصدر: Biomolecules, Vol 11, Iss 1134, p 1134 (2021)
Biomolecules
Volume 11
Issue 8
Biomolecules 11 (2021). doi:10.3390/biom11081134
info:cnr-pdr/source/autori:Vitale R.M.; Iannotti F.A.; Moriello A.S.; Tunisi L.; Piscitelli F.; Savopoulos R.; Cristino L.; De Petrocellis L.; Amodeo P.; Gray R.; Di Marzo V./titolo:Identification and characterization of cannabidiol as an ox1r antagonist by computational and in vitro functional validation/doi:10.3390%2Fbiom11081134/rivista:Biomolecules/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:11

مصطلحات موضوعية: Protein Conformation, alpha-Helical, 0301 basic medicine, Gene Expression, Pharmacology, Biochemistry, Radioligand Assay, cannabidiol, 0302 clinical medicine, Transgenes, Receptor, media_common, Chemistry, calcium mobilization assay, Ligand (biochemistry), calcium influx assay, Orexin receptor, QR1-502, Molecular Imaging, Molecular Docking Simulation, calcium imaging, Anticonvulsants, Orexin Receptor Antagonists, Protein Binding, medicine.drug, Drug, orexin receptors, OX1R, media_common.quotation_subject, CHO Cells, Microbiology, Article, 03 medical and health sciences, Cricetulus, medicine, Animals, Humans, Protein Interaction Domains and Motifs, Molecular Biology, Orexins, Binding Sites, Antagonist, antagonist, molecular docking, In vitro, molecular dynamics, Orexin, Kinetics, 030104 developmental biology, Anti-Anxiety Agents, Calcium, Protein Conformation, beta-Strand, Cannabidiol, 030217 neurology & neurosurgery