نتائج البحث

1

Molecular characterization of HLA class II binding to the LAG‐3 T cell co‐inhibitory receptor

المؤلفون: Georgina H. Mason, David K. Cole, Frédéric Triebel, Awen Gallimore, Andrew James Godkin, Bruce J. MacLachlan, Alexander Greenshields-Watson

المصدر: European Journal of Immunology

مصطلحات موضوعية: 0301 basic medicine, Molecular immunology and signaling, LAG3, T-Lymphocytes, medicine.medical_treatment, T cell, Immunology, Cell, T cells, Receptors, Antigen, T-Cell, Biology, immune checkpoint inhibitors, Jurkat Cells, 03 medical and health sciences, 0302 clinical medicine, LAG‐3, Costimulatory and Inhibitory T-Cell Receptors, Downregulation and upregulation, Cancer immunotherapy, Antigens, CD, HLA Antigens, Cell Line, Tumor, Neoplasms, medicine, Humans, Immunology and Allergy, Basic, Receptor, Research Articles, cancer immunotherapy, Lymphocyte Activation Gene 3 Protein, 3. Good health, Cell biology, 030104 developmental biology, medicine.anatomical_structure, CD4 Antigens, pHLA‐II, biology.protein, Research Article|Basic, Antibody, Function (biology), 030215 immunology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295dfce87346771adca4707fe21a976bTest
https://doi.org/10.1002/eji.202048753Test

2

Case Report: Circulating Myeloid-Derived Suppressive-Like Cells and Exhausted Immune Cells in Non-Small Cell Lung Cancer Patients Treated With Three Immune Checkpoint Inhibitors

المؤلفون: Giuseppe Bronte, Alberto Verlicchi, Serena De Matteis, Alice Rossi, Alessandra Affatato, Francesco Giulio Sullo, Caterina Gianni, Matteo Canale, Marco Angelo Burgio, Angelo Delmonte, Michele Milella, Lucio Crinò

المصدر: Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)

مصطلحات موضوعية: Male, 0301 basic medicine, Lung Neoplasms, Myeloid, medicine.medical_treatment, Immunology, immune checkpoint inhibitor, Adenocarcinoma of Lung, Case Report, chemical and pharmacologic phenomena, 03 medical and health sciences, 0302 clinical medicine, Immune system, Cancer immunotherapy, LAG-3, Antineoplastic Combined Chemotherapy Protocols, PD-1, medicine, Humans, Immunology and Allergy, Lung cancer, Immune Checkpoint Inhibitors, Aged, T cell exhaustion, business.industry, Cancer, RC581-607, Middle Aged, biochemical phenomena, metabolism, and nutrition, myeloid-derived suppressor cells, medicine.disease, Ipilimumab, Immune checkpoint, Nivolumab, 030104 developmental biology, medicine.anatomical_structure, CTLA-4, 030220 oncology & carcinogenesis, Cancer research, Myeloid-derived Suppressor Cell, Tumor Escape, Immunologic diseases. Allergy, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5ad11e5b5cf86e4ec09d57949b4bf71Test
https://doi.org/10.3389/fimmu.2021.672219Test

3

PD-1 and LAG-3 blockade improve anti-tumor vaccine efficacy

المؤلفون: Douglas G. McNeel, Jena E Moseman, Christopher D. Zahm, Lauren E. Delmastro

المصدر: Oncoimmunology
article-version (VoR) Version of Record
OncoImmunology, Vol 10, Iss 1 (2021)

مصطلحات موضوعية: 0301 basic medicine, Male, Immunology, Programmed Cell Death 1 Receptor, Pharmacology, CD8-Positive T-Lymphocytes, Cancer Vaccines, 03 medical and health sciences, Mice, 0302 clinical medicine, LAG-3, Antigens, CD, Neoplasms, PD-1, Vaccines, DNA, Immunology and Allergy, Medicine, Animals, Receptor, RC254-282, Original Research, Antitumor activity, business.industry, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC581-607, Vaccine efficacy, Lymphocyte Activation Gene 3 Protein, Blockade, APC, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, tumor vaccine, biological phenomena, cell phenomena, and immunity, Immunologic diseases. Allergy, business, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b7b0cb62418920deac12684eed2b8daTest
https://pubmed.ncbi.nlm.nih.gov/33996265Test

4

TIM-3 levels correlate with enhanced NK cell cytotoxicity and improved clinical outcome in AML patients

المؤلفون: Marek Kovar, Lorenzo Galluzzi, Jana Rakova, Justin Kline, Jitka Fucikova, Peter Holicek, Josef Pasulka, Monika Holubova, Iva Truxova, Zdenek Racil, Radek Spisek, Daniel Lysák, Cyril Salek, Michal Hensler, Lenka Kasikova

المصدر: Oncoimmunology
article-version (VoR) Version of Record
OncoImmunology, Vol 10, Iss 1 (2021)

مصطلحات موضوعية: 0301 basic medicine, lag-3, Immunology, innate lymphoid cells, CD8-Positive T-Lymphocytes, HAVCR2, 03 medical and health sciences, 0302 clinical medicine, Immune system, TIGIT, hemic and lymphatic diseases, tigit, Immunology and Allergy, Medicine, Cytotoxic T cell, Humans, Co-inhibitory receptor, Hepatitis A Virus Cellular Receptor 2, RC254-282, Original Research, business.industry, Innate lymphoid cell, Myeloid leukemia, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC581-607, Killer Cells, Natural, CTL, Leukemia, Myeloid, Acute, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Cancer research, vista, Immunologic diseases. Allergy, business, CD8, T-Lymphocytes, Cytotoxic, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c219a2ae8bc43638000406a3d711f16Test
https://pubmed.ncbi.nlm.nih.gov/33758676Test

5

Triple-Negative Breast Cancer: Intact Mismatch Repair and Partial Co-Expression of PD-L1 and LAG-3

المؤلفون: Xuan Zeng, Xiaohua Shi, Yuanyuan Liu, Shafei Wu, Feng Mao, Yufeng Luo, Xuefei Wang, Jing Wang

المصدر: Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)

مصطلحات موضوعية: lcsh:Immunologic diseases. Allergy, PD-L1, 0301 basic medicine, Population, Immunology, Gene Expression, Triple Negative Breast Neoplasms, DNA Mismatch Repair, B7-H1 Antigen, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, LAG-3, Antigens, CD, medicine, Humans, Immunology and Allergy, education, In Situ Hybridization, Fluorescence, Triple-negative breast cancer, Original Research, Aged, Mismatch Repair Endonuclease PMS2, Retrospective Studies, education.field_of_study, Predictive marker, biology, business.industry, Microsatellite instability, CD8, Middle Aged, medicine.disease, Immunohistochemistry, Lymphocyte Activation Gene 3 Protein, DNA-Binding Proteins, MutS Homolog 2 Protein, 030104 developmental biology, 030220 oncology & carcinogenesis, triple-negative breast cancer, Cancer research, biology.protein, Female, Microsatellite Instability, DNA mismatch repair, lcsh:RC581-607, MutL Protein Homolog 1, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34f8638be7b5d5c3455a7f2a20b9865dTest

6

Analysis of Co-inhibitory Receptor Expression in COVID-19 Infection Compared to Acute Plasmodium falciparum Malaria: LAG-3 and TIM-3 Correlate With T Cell Activation and Course of Disease

المؤلفون: Marissa Herrmann, Sophia Schulte, Nils H. Wildner, Melanie Wittner, Thomas Theo Brehm, Michael Ramharter, Robin Woost, Ansgar W. Lohse, Thomas Jacobs, Julian Schulze zur Wiesch

المصدر: Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Male, 0301 basic medicine, CD226, Receptor expression, Programmed Cell Death 1 Receptor, CD8-Positive T-Lymphocytes, Lymphocyte Activation, Severity of Illness Index, Cohort Studies, 0302 clinical medicine, PD-1, Immunology and Allergy, Malaria, Falciparum, Hepatitis A Virus Cellular Receptor 2, Cells, Cultured, Original Research, Middle Aged, Lymphocyte Activation Gene 3 Protein, medicine.anatomical_structure, Acute Disease, Female, Coronavirus Infections, Adult, lcsh:Immunologic diseases. Allergy, T cell, TIM-3, Pneumonia, Viral, Immunology, Plasmodium falciparum, Receptors, Antigen, T-Cell, malaria, T cells, Biology, Betacoronavirus, 03 medical and health sciences, Immune system, TIGIT, Antigens, CD, LAG-3, medicine, Humans, Pandemics, B cell, Aged, SARS-CoV-2, COVID-19, biology.organism_classification, 030104 developmental biology, lcsh:RC581-607, CD8, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcbd8887b17f94bd2b4a9486de44fe53Test
http://europepmc.org/articles/PMC7479337Test

7

Blockade of LAG-3 in PD-L1-deficient mice enhances clearance of blood stage malaria independent of humoral responses

المؤلفون: Raquel Furtado, Laurent Chorro, Natalie Zimmerman, Erik Guillen, Emily Spaulding, Shu Shien Chin, Johanna P. Daily, Grégoire Lauvau

المصدر: Frontiers in Immunology, Vol 11 (2021)
Frontiers in Immunology

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Male, 0301 basic medicine, Helper T lymphocyte, Programmed Cell Death 1 Receptor, Parasitemia, B7-H1 Antigen, Mice, 0302 clinical medicine, humoral immunity, Immunology and Allergy, Cytotoxic T cell, Malaria, Falciparum, Receptor, Immune Checkpoint Inhibitors, Cells, Cultured, Original Research, Mice, Knockout, checkpoint therapeutic blockade, biology, Chemistry, Antibodies, Monoclonal, Lymphocyte Activation Gene 3 Protein, medicine.anatomical_structure, PD-1/PD-L1/LAG-3, Antibody, LAG-3+ CD4+ and CD8+ T cells, lcsh:Immunologic diseases. Allergy, PD-L1 and PD-1 knockout mice, T cell, Plasmodium falciparum, Immunology, malaria, 03 medical and health sciences, Antigens, CD, medicine, Animals, Humans, B cell, Life Cycle Stages, Innate immune system, Germinal center, Plasmodium yoelii, medicine.disease, Immunity, Humoral, Blockade, Mice, Inbred C57BL, Disease Models, Animal, inhibitory receptors, 030104 developmental biology, Humoral immunity, biology.protein, lcsh:RC581-607, CD8, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::305420b91ea57b86b751b5a233d9a244Test
https://doi.org/10.1101/2020.06.22.164566Test

8

Ectopic expression of LAG‐3 in non–small‐cell lung cancer cells and its clinical significance

المؤلفون: Dong Shen, Naifu Guan, Yuejun Sun, Chunjian Qi, Chenglong Ma, Xiao Sun

المصدر: Journal of Clinical Laboratory Analysis

مصطلحات موضوعية: 0301 basic medicine, Microbiology (medical), Male, Lung Neoplasms, non–small‐cell lung cancer, Clinical Biochemistry, Flow cytometry, Ectopic Gene Expression, ectopic expression, 03 medical and health sciences, 0302 clinical medicine, Western blot, LAG‐3, Antigens, CD, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, medicine, Biomarkers, Tumor, Immunology and Allergy, Humans, Clinical significance, Lung cancer, Research Articles, medicine.diagnostic_test, business.industry, Biochemistry (medical), Public Health, Environmental and Occupational Health, Hematology, medicine.disease, Lymphocyte Activation Gene 3 Protein, Immune checkpoint, respiratory tract diseases, tumor immunity, Blot, Survival Rate, Medical Laboratory Technology, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer research, Immunohistochemistry, Ectopic expression, Female, business, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a92cb79ddcef47671634a5d6a7493468Test
http://europepmc.org/articles/PMC7307345Test

9

Genomic and immunologic correlates of LAG-3 expression in cancer

المؤلفون: Anshuman Panda, Shridar Ganesan, Jeffrey A. Rosenfeld, Gyan Bhanot, Eric A. Singer

المصدر: OncoImmunology, Vol 9, Iss 1 (2020)
Oncoimmunology
article-version (VoR) Version of Record

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cc5e16c0372d2ac2818913d6c85ab77Test
https://doaj.org/article/d6dc8bdc526445cebab749c6c5ee6faaTest

10

Armed oncolytic viruses: A kick-start for anti-tumor immunity

المؤلفون: B G van den Hoogen, Ron A. M. Fouchier, J.F. de Graaf, L. de Vor

المساهمون: Virology

المصدر: Cytokine & Growth Factor Reviews, 41, 28-39. Elsevier
Cytokine & Growth Factor Reviews

مصطلحات موضوعية: 0301 basic medicine, PD-L1, programmed death ligand 1, Endocrinology, Diabetes and Metabolism, OV, oncolytic virus, Oncolytic viruses, HPGD, hydroxyprostaglandin dehydrogenase, APC, antigen presenting cell, DC, dendritic cell, Neoplasms, Tumor Microenvironment, CTLA-4, cytotoxic T lymphocyte antigen 4, Immunology and Allergy, Medicine, Transgenes, TGF, transforming growth factor, TIM-3, T cell immunoglobulin domain and mucin domain-3, TAA, tumor associated antigen, DAMPs, damage-associated molecular pattern molecules, TNF, tumor necrosis factor, Antitumor immunity, GITRL, glucocorticoid-induced TNFR-related protein, TME, tumor microenvironment, HMGB1, high-mobility group protein B1, IDO, indoleamine 2,3-dioxygenase, Immune Modulators, MYXV, myxoma virus, GM-CSF, granulocyte-macrophage colony-stimulating factor, NK, natural killer, MDSC, myeloid derived suppressor cell, ATP, adenosine triphosphate, VSV, vesicular stomatitis virus, Transgene, Immunology, Cancer therapy, Antineoplastic Agents, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Immune system, IAV, influenza A virus, Immunologic Factors, Animals, Humans, MHC, major histocompatibility complex, PGE2, prostaglandin 2, IFN, interferon, VV, vaccinia virus, ComputingMethodologies_COMPUTERGRAPHICS, AdV, adenovirus, Tumor microenvironment, business.industry, CXCL/CCL, C-X-C motif ligands, CTL, cytotoxic T lymphocyte, MV, measles virus, Tumor associated antigen, IL, interleukin, Oncolytic virus, 030104 developmental biology, Immune therapy, Cancer research, NDV, Newcastle diseases virus, HSV, Herpes Simplex Virus, LAG-3, lymphocyte-activation gene 3 protein, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6211cc5159917e425feda430c90c8c96Test
https://doi.org/10.1016/j.cytogfr.2018.03.006Test

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