يعرض 1 - 4 نتائج من 4 نتيجة بحث عن '"T cell proliferation"', وقت الاستعلام: 0.69s تنقيح النتائج
  1. 1
    PD-1 silencing impairs the anti-tumor function of chimeric antigen receptor modified T cells by inhibiting proliferation activity

    المؤلفون: Dongdong Ti, Jianshu Wei, Hanren Dai, Yelei Guo, Yao Wang, Weidong Han, Can Luo, Chuan Tong, Zhiqiang Wu

    المصدر: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-15 (2019)
    Journal for Immunotherapy of Cancer

    مصطلحات موضوعية: 0301 basic medicine, Cancer Research, T cell, T-Lymphocytes, Immunology, Programmed Cell Death 1 Receptor, PD-1 blockade, T cell differentiation, Lymphocyte Activation, lcsh:RC254-282, T cell proliferation, Small hairpin RNA, Persistence, 03 medical and health sciences, Mice, 0302 clinical medicine, Mice, Inbred NOD, medicine, Immunology and Allergy, Gene silencing, Animals, Humans, Pharmacology, Chimeric antigen receptor modified T cells, Gene knockdown, Receptors, Chimeric Antigen, Chemistry, Cell Differentiation, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Chimeric antigen receptor, In vitro, Blockade, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Oncology, A549 Cells, 030220 oncology & carcinogenesis, Gene Knockdown Techniques, Molecular Medicine, Female, Research Article

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d3f773bf99bc326da6fe01d43aed453Test
    http://link.springer.com/article/10.1186/s40425-019-0685-yTest


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  2. 2
    Pitavastatin Is a Highly Potent Inhibitor of T-Cell Proliferation

    المؤلفون: Dirk Reinhold, Linda Voss, Annika Reddig, Burkhart Schraven, Karina Guttek, Martin Voss, Luca Simeoni, Annegret Reinhold

    المصدر: Pharmaceuticals
    Volume 14
    Issue 8
    Pages: 727
    Pharmaceuticals, Vol 14, Iss 727, p 727 (2021)

    مصطلحات موضوعية: 0301 basic medicine, T cell, Pharmaceutical Science, Hyperphosphorylation, Mevalonic acid, drug repositioning, Pharmacology, Reductase, Article, 03 medical and health sciences, chemistry.chemical_compound, Pharmacy and materia medica, 0302 clinical medicine, Drug Discovery, medicine, ERK1/2 activation, Pitavastatin, biology, apoptosis, CD28, RS1-441, 030104 developmental biology, medicine.anatomical_structure, chemistry, Apoptosis, 030220 oncology & carcinogenesis, inhibitor of T-cell proliferation, HMG-CoA reductase, biology.protein, Medicine, Molecular Medicine, medicine.drug

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18561f6b6feb0611b1021d61850cde09Test


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  3. 3
    Immunosuppressive potential of astemizole against LPS activated T cell proliferation and cytokine secretion in RAW macrophages, zebrafish larvae and mouse splenocytes by modulating MAPK signaling pathway

    المؤلفون: Chanchal Sharma, Sun Chul Kang, Rekha Jakhar, Souren Paul

    المصدر: International Immunopharmacology. 65:268-278

    مصطلحات موضوعية: Fish Proteins, Lipopolysaccharides, 0301 basic medicine, MAPK/ERK pathway, Lipopolysaccharide, T-Lymphocytes, T cell, Immunology, Activated T cell proliferation, Pharmacology, Lymphocyte Activation, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Immune system, medicine, Animals, Immunology and Allergy, Extracellular Signal-Regulated MAP Kinases, Zebrafish, Cell Proliferation, Innate immune system, Chemistry, Macrophages, Astemizole, RAW 264.7 Cells, 030104 developmental biology, medicine.anatomical_structure, Larva, 030220 oncology & carcinogenesis, Cytokines, Cytokine secretion, Tumor necrosis factor alpha, Immunosuppressive Agents, Spleen, Signal Transduction

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ecbf175c7eba1d77e6ffa381ec47c6Test
    https://doi.org/10.1016/j.intimp.2018.10.014Test


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  4. 4
    Inhibition of tryptophan-dioxygenase activity increases the antitumor efficacy of immune checkpoint inhibitors

    المؤلفون: Luc Pilotte, Delia Hoffmann, Vincent Stroobant, Julie Preillon, Kim Frederix, Stefano Crosignani, Florence Schramme, Gregory Driessens, Benoît Van den Eynde

    المساهمون: UCL - SSS/DDUV - Institut de Duve, UCL - SSS/DDUV/GECE - Génétique cellulaire, UCL - SSS/IREC/MORF - Pôle de Morphologie

    المصدر: Cancer immunology research, Vol. 8, no. 1, p. 32-45 (2020)

    مصطلحات موضوعية: 0301 basic medicine, Cancer Research, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Pharmacology, chemistry.chemical_compound, Mice, 0302 clinical medicine, Antineoplastic Agents, Immunological, IDO1, Cancer immunotherapy, Oral administration, RESISTANCE MECHANISM, CTLA-4 Antigen, Enzyme Inhibitors, Kynurenine, Mice, Knockout, Mice, Inbred BALB C, Dioxygenase activity, INTERSTITIAL FLUID, Tryptophan, Immunosuppression, Drug Synergism, MOUSE MODEL, CANCER, Tryptophan Oxygenase, INDOLEAMINE 2,3-DIOXYGENASE EXPRESSION, Oncology, 030220 oncology & carcinogenesis, Colonic Neoplasms, Life Sciences & Biomedicine, Immunology, DENDRITIC CELLS, Small Molecule Libraries, 03 medical and health sciences, Cell Line, Tumor, medicine, Animals, Humans, SUPPRESSION, T-CELL PROLIFERATION, Science & Technology, INTERFERON-GAMMA, Immunotherapy, Neoplasms, Experimental, Mice, Inbred C57BL, 030104 developmental biology, chemistry, Cell culture

    وصف الملف: Print-Electronic

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36082075ff24fda1d254c695e3510f11Test
    https://ora.ox.ac.uk/objects/uuid:e4f52d6c-351b-4a2f-b6d4-73f56fe26dc1Test


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