المؤلفون: Tasset, Celine, Singh Yadav, Avilash, Sureshkumar, Sridevi, Singh, Rupali, van der Woude, Lennard, Nekrasov, Maxim, Tremethick, David, van Zanten, Martijn, Balasubramanian, Sureshkumar, Sub Molecular Plant Physiology, Molecular Plant Physiology

المساهمون: Sub Molecular Plant Physiology, Molecular Plant Physiology

المصدر: PLoS Genetics, Vol 14, Iss 3, p e1007280 (2018)
PLoS Genetics, 14(3). Public Library of Science
PLoS Genetics

مصطلحات موضوعية: 0301 basic medicine, 0106 biological sciences, Cancer Research, Fruit and Seed Anatomy, Arabidopsis, Histones/metabolism, Gene Expression, Plant Science, Biochemistry, 01 natural sciences, Histones, Histone methylation, Morphogenesis, Arabidopsis thaliana, Histone code, Genetics (clinical), Plant Growth and Development, Regulation of gene expression, 2. Zero hunger, Genetics, 0303 health sciences, Chromosome Biology, Plant Anatomy, Temperature, Eukaryota, food and beverages, Acetylation, Genomics, Plants, Hypocotyl, Chromatin, Nucleosomes, Cell biology, Arabidopsis Proteins/genetics, Histone, Experimental Organism Systems, Histone methyltransferase, Embryogenesis, Epigenetics, Transcriptome Analysis, Research Article, lcsh:QH426-470, Arabidopsis Thaliana, Transcription Factors/genetics, Plant Development, Brassica, SAP30, Biology, Research and Analysis Methods, Histone Deacetylases, Chromatin remodeling, 03 medical and health sciences, Model Organisms, Histone H1, Plant and Algal Models, DNA-binding proteins, Histone H2A, Nucleosome, Gene Regulation, Arabidopsis/genetics, Molecular Biology, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, Biology and life sciences, Plant Embryo Anatomy, Arabidopsis Proteins, HDAC9, Organisms, Proteins, Computational Biology, Cell Biology, Genome Analysis, biology.organism_classification, lcsh:Genetics, 030104 developmental biology, Mutation, biology.protein, Histone Deacetylases/metabolism, Plant Embryogenesis, Developmental Biology, Transcription Factors, 010606 plant biology & botany

وصف الملف: image/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d57a60975b88b4bf219bb7925e75a4bbTest
https://doi.org/10.1101/186916Test

المؤلفون: Victor Fernandes Vieira, Sandrine Cornaz, Luisa Cironi, Carlo Fusco, Paolo Provero, Giulia Fregni, Ivan Stamenkovic, Igor Letovanec, Michel Aguet, Tanja Petricevic

المصدر: Scientific Reports
Scientific reports, vol. 6, pp. 22113

مصطلحات موضوعية: 0301 basic medicine, Beta-catenin, Oncogene Proteins, Fusion, Blotting, Western, Animals, Axin Protein/genetics, Axin Protein/metabolism, Cell Line, Cell Line, Tumor, Gene Expression Profiling/methods, Histone Deacetylases/genetics, Histone Deacetylases/metabolism, Humans, Mice, Microscopy, Confocal, Oncogene Proteins, Fusion/genetics, Oncogene Proteins, Fusion/metabolism, RNA Interference, Repressor Proteins/genetics, Repressor Proteins/metabolism, Reverse Transcriptase Polymerase Chain Reaction, Sarcoma, Synovial/genetics, Sarcoma, Synovial/metabolism, Sarcoma, Synovial/pathology, TCF Transcription Factors/genetics, TCF Transcription Factors/metabolism, Transcription Factors/genetics, Transcription Factors/metabolism, Wnt Signaling Pathway/genetics, beta Catenin/genetics, beta Catenin/metabolism, TCF/LEF family, Histone Deacetylases, Article, Sarcoma, Synovial, 03 medical and health sciences, Axin Protein, AXIN2, Fusion, Wnt Signaling Pathway, Transcription factor, beta Catenin, Gene Expression Profiling, Repressor Proteins, TCF Transcription Factors, Transcription Factors, Multidisciplinary, Oncogene Proteins, Microscopy, Tumor, Synovial, biology, Blotting, Wnt signaling pathway, LRP6, Sarcoma, LRP5, Fusion protein, 030104 developmental biology, Confocal, biology.protein, Cancer research, Western, Co-Repressor Proteins

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60efadcc1928d9d1f484ba21cc89d788Test
https://doi.org/10.1038/srep22113Test

المؤلفون: Muriel Cuendet, Claudia A. Simões-Pires, Vincent Zwick

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 31, No sup1 (2016) pp. 209-214

مصطلحات موضوعية: 0301 basic medicine, Spectrometry, Mass, Electrospray Ionization, High-throughput screening, Cell, Drug Evaluation, Preclinical, Molecular Conformation, Histone Deacetylase 1, Pharmacology, Histone Deacetylase 6, Histone Deacetylases, Dose-Response Relationship, 03 medical and health sciences, Structure-Activity Relationship, Histone Deacetylase Inhibitors/analysis/chemistry/pharmacology, Drug Discovery, medicine, Humans, Chromatography, High Pressure Liquid, chemistry.chemical_classification, Histone Deacetylase 1/antagonists & inhibitors/metabolism, ddc:615, Chromatography, Dose-Response Relationship, Drug, biology, Drug discovery, Spectrometry, Electrospray Ionization, Cancer, General Medicine, HDAC6, Mass, medicine.disease, Histone Deacetylase Inhibitors, 030104 developmental biology, medicine.anatomical_structure, Histone, Enzyme, chemistry, Preclinical/methods, High Pressure Liquid, biology.protein, Drug Evaluation, Histone deacetylase, Histone Deacetylases/metabolism, Drug, HeLa Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::883ab462cbcd9a7751ca36c6ff377bbeTest
https://archive-ouverte.unige.ch/unige:94975Test

المؤلفون: Judit Ovádi, Claudia A. Simões-Pires, Attila Lehotzky, Alessandra Nurisso, Philippe Bertrand, Muriel Cuendet, Nadine Martinet, Samuel Bouchet, Vincent Zwick, Christophe Blanquart

المساهمون: School of Pharmaceutical Sciences, Université de Lausanne (UNIL)-University of Geneva [Switzerland], Réseau épigénétique, Cancéropôle Grand-Ouest, Institut de Chimie des Milieux et Matériaux de Poitiers (IC2MP), Université de Poitiers-Institut national des sciences de l'Univers (INSU - CNRS)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Institut de Chimie de Nice (ICN), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), Institute of Enzymology [Budapest], Research Centre for Natural Sciences, Hungarian Academy of Sciences (MTA)-Hungarian Academy of Sciences (MTA), Centre de Recherche en Cancérologie Nantes-Angers (CRCNA), Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)-PRES Université Nantes Angers Le Mans (UNAM)-Hôtel-Dieu de Nantes-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hôpital Laennec-Centre National de la Recherche Scientifique (CNRS)-Faculté de Médecine d'Angers-Centre hospitalier universitaire de Nantes (CHU Nantes), Authors thank the Centre National de la Recherche Scientifique– France, University of Poitiers, Region Poitou-Charentes (S.B. financial support), the Ligue Contre le Cancer: Committees of Vendée, et Charente-Maritime – France, ARSMeso44 – France, COST Actions CM1406 and CM1106 – Belgium and Hungarian OTKA Founds K-101039 and K-112144 for financial support. A.N. thanks the Excellence programme of the University of Geneva –Switzerland for financial support., Bernardo, Elizabeth, Université de Lausanne = University of Lausanne (UNIL)-Université de Genève = University of Geneva (UNIGE), Université Nice Sophia Antipolis (1965 - 2019) (UNS)

المصدر: Bioorganic and Medicinal Chemistry Letters
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2016, ⟨10.1016/j.bmcl.2015.11.011⟩
Bioorganic and Medicinal Chemistry Letters, 2016, ⟨10.1016/j.bmcl.2015.11.011⟩
Bioorganic & Medicinal Chemistry Letters, Vol. 26, No 1 (2016) pp. 154-159

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Intrinsic activity, Formic Acid Esters, Stereochemistry, Clinical Biochemistry, Convergent synthesis, Pharmaceutical Science, [SDV.CAN]Life Sciences [q-bio]/Cancer, Alkenes, Hydroxamic Acids, Metathesis, Biochemistry, Histone Deacetylases, Catalysis, Dose-Response Relationship, Formic Acid Esters/chemistry, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, [SDV.CAN] Life Sciences [q-bio]/Cancer, Models, Drug Discovery, Humans, Structure–activity relationship, Benzamides/chemistry, Benzamide, Molecular Biology, ddc:615, Dose-Response Relationship, Drug, Molecular Structure, biology, Organic Chemistry, Molecular, Alkenes/chemistry, 3. Good health, Histone Deacetylase Inhibitors, 030104 developmental biology, Tubulin, Histone Deacetylase Inhibitors/chemistry/pharmacology, Hydroxamic Acids/chemistry, chemistry, Benzamides, biology.protein, Molecular Medicine, Histone Deacetylases/metabolism, Drug, Selectivity

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acc9fefa73c13b45a09cef22d951db0cTest
https://www.hal.inserm.fr/inserm-01299475/documentTest

المؤلفون: Michelandrea De Cesare, Muriel Cuendet, Sabrina Dallavalle, Vincent Zwick, Giuseppe Giannini, Alessandra Nurisso, Raffaella Cincinelli, Valentina Zuco, Loana Musso, Franco Zunino, Claudia A. Simões-Pires

المصدر: European Journal of Medicinal Chemistry, Vol. 112 (2016) pp. 99-105

مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, Antineoplastic Agents, Apoptosis, Drug Screening Assays, Hydroxamic Acids, Histone Deacetylases, Histone H4, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, In vivo, Neoplasms, Drug Discovery, Structure–activity relationship, Humans, Biphenyl Compounds/chemistry/pharmacology, Pharmacology, ddc:615, Neoplasms/drug therapy/metabolism, biology, Colonic Neoplasms/drug therapy/metabolism, Apoptosis/drug effects, Organic Chemistry, Biphenyl Compounds, Active site, Antitumor, General Medicine, HCT116 Cells, In vitro, Hydroxamic Acids/chemistry/pharmacology, Biphenyl compound, Histone Deacetylase Inhibitors, Molecular Docking Simulation, 030104 developmental biology, Histone Deacetylase Inhibitors/chemistry/pharmacology, chemistry, Biochemistry, Acetylation, Colonic Neoplasms, biology.protein, Histone Deacetylases/metabolism, Antineoplastic Agents/chemistry/pharmacology, Drug Screening Assays, Antitumor, Derivative (chemistry)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c41240a5dcd709036f451727b80a3b2Test
https://pubmed.ncbi.nlm.nih.gov/26890116Test