المؤلفون: Ethel Cesarman, Ashley S. Doane, Andreas Kloetgen, Joseph Conway, Jeannie M. Camarillo, Olivier Elemento, Neil L. Kelleher, Stephanie Portillo-Ledesma, Adewola Osunsade, Christopher E. Mason, Bryan J. Venters, Ari Melnick, Yael David, Alexey A. Soshnev, Tamar Schlick, Marcin Imielinski, David Scott, Aristotelis Tsirigos, Christopher R. Chin, Wendy Béguelin, Eftychia Apostolou, Arthur I. Skoultchi, Jonathan D. Licht, C. David Allis, Louis M. Staudt, Jude M. Phillip, Nevin Yusufova, Michael-Christopher Keogh, Matt Teater

المصدر: Nature

مصطلحات موضوعية: 0301 basic medicine, Lymphoma, medicine.disease_cause, Article, Epigenesis, Genetic, Histones, 03 medical and health sciences, Histone H3, Mice, 0302 clinical medicine, Histone H1, medicine, Nucleosome, Animals, Humans, Genes, Tumor Suppressor, Epigenetics, Gene Silencing, Cell Self Renewal, Alleles, Regulation of gene expression, Mutation, B-Lymphocytes, Multidisciplinary, biology, Stem Cells, Chromatin Assembly and Disassembly, Germinal Center, Chromatin, Cell biology, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Histone, Cell Transformation, Neoplastic, 030220 oncology & carcinogenesis, biology.protein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57badeea50b93be34e01e83a6c86b178Test
http://europepmc.org/articles/PMC7855728Test

المؤلفون: Arthur V. Hauenstein, Seong Ho Hong, David Rooklin, Archana Gautam, Ethel Cesarman, Michael G. Wuo, Jouliana Sadek, Yingkai Zhang, Hao Wu, Paramjit S. Arora

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications

مصطلحات موضوعية: Male, 0301 basic medicine, Scaffold protein, congenital, hereditary, and neonatal diseases and abnormalities, Science, General Physics and Astronomy, Protein degradation, 010402 general chemistry, Models, Biological, 01 natural sciences, Article, General Biochemistry, Genetics and Molecular Biology, Epitope, Cell Line, Mice, 03 medical and health sciences, Lymphoma, Primary Effusion, medicine, Animals, Humans, Tumour virus infections, lcsh:Science, skin and connective tissue diseases, Coiled coil, Microscopy, Confocal, Multidisciplinary, Chemistry, Circular Dichroism, Intracellular Signaling Peptides and Proteins, NF-kappa B, Rational design, food and beverages, General Chemistry, medicine.disease, Xenograft Model Antitumor Assays, Small molecule, Protein tertiary structure, I-kappa B Kinase, 0104 chemical sciences, Cell biology, 030104 developmental biology, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Herpesvirus 8, Human, lcsh:Q, Primary effusion lymphoma, Peptides, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6650e4f189316ffca5a4499439ab6edTest
https://doaj.org/article/c91a73658de949548aa1a6962b0fe8cdTest

المؤلفون: Michael Stürzl, Christoph Becker, Ethel Cesarman, Barbara Ruder, Claudia Günther, Markus F. Neurath, Gianna Ballon

المصدر: PLoS ONE
PLoS ONE, Vol 15, Iss 1, p e0228441 (2020)

مصطلحات موضوعية: 0301 basic medicine, CASP8 and FADD-Like Apoptosis Regulating Protein, Gene Expression, Apoptosis, Epithelium, Mice, 0302 clinical medicine, Animal Cells, Medizinische Fakultät, Gene expression, Medicine and Health Sciences, Intestinal Mucosa, Organ Cultures, Caspase 8, Multidisciplinary, Cell Death, Animal Models, Intestinal epithelium, Cell biology, Organoids, Experimental Organism Systems, Cell Processes, 030220 oncology & carcinogenesis, Herpesvirus 8, Human, Models, Animal, Medicine, Biological Cultures, Anatomy, Cellular Types, Research Article, Programmed cell death, Science, Mouse Models, Biology, Research and Analysis Methods, Necrotic Cell Death, Viral Proteins, 03 medical and health sciences, Model Organisms, Genetics, Homologous chromosome, Animals, Humans, ddc:610, Cell Proliferation, Cell growth, Biology and Life Sciences, Epithelial Cells, Cell Biology, Gastrointestinal Tract, Biological Tissue, 030104 developmental biology, Flip, Animal Studies, Digestive System, Gene Deletion

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b8996b60c4d5fde87130cb90639d59Test
https://opus4.kobv.de/opus4-fau/frontdoor/index/index/docId/14276Test

المؤلفون: Denise Hernandez-Hopkins, Kenneth M. Kaye, Yifang Liu, J. David Warren, Jennifer Totonchy, Ethel Cesarman, Ruben Niesvizky, Ilaria Guasparri, Peter Barelli, David Jayabalan, Hufeng Zhou, Olivier Elemento, Duane C. Hassane, Michelle A. Sahai, Robert H. Shoemaker, Gunkut Akar, Utthara Nayar, Shizuko Sei, Jonathan Reichel, Jouliana Sadek

المصدر: Journal of Clinical Investigation. 127:2066-2080

مصطلحات موضوعية: Male, 0301 basic medicine, Cell Survival, T cell, Antineoplastic Agents, Mice, SCID, Adenosine kinase, Biology, Plasma cell, Inhibitory Concentration 50, Mice, 03 medical and health sciences, Mice, Inbred NOD, Cell Line, Tumor, Lymphoma, Primary Effusion, hemic and lymphatic diseases, medicine, Animals, Humans, Adenosine Kinase, Purine Nucleosides, General Medicine, medicine.disease, Xenograft Model Antitumor Assays, 3. Good health, ADK, Lymphoma, 030104 developmental biology, medicine.anatomical_structure, Drug Resistance, Neoplasm, Cancer research, biology.protein, Primary effusion lymphoma, Nucleoside, Plasmablastic lymphoma, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28a8b8524ba3f0393b11c0ead03b0737Test
https://doi.org/10.1172/jci83936Test

المؤلفون: Oscar Lin, Robert Trondl, Brad Beattie, Ari Melnick, Anna Rodina, Alexander Bolaender, Ross L. Levine, Ethel Cesarman, Pat Zanzonico, Gabriela Chiosis, Pengrong Yan, Chenghua Yang, Jason S. Lewis, Sujata Patil, Tony Taldone, John F. Gerecitano, Leandro Cerchietti, Sarah Kishinevsky, Clifford A. Hudis, Radu I Peter, Fumiko Shimizu, Monica L. Guzman, Matthew Riolo, Mohammad F. Farooq, Erica DaGama Gomes, John Koren, Hardik J. Patel, Hediye Erdjument-Bromage, Gail J. Roboz, Nagavarakishore Pillarsetty, Lorenz Studer, Mark Dunphy, Tai Wang, Hongliang Zong, Shanu Modi, Palak Panchal, Eloisi Caldas-Lopes, Mary L. Alpaugh, Christina Pressl, Chao Xu, Steven M. Larson, Feixia Chu, Adriana D. Corben

المصدر: Nature. 538:397-401

مصطلحات موضوعية: 0301 basic medicine, Protein family, Cell Survival, Genes, myc, Cellular homeostasis, Antineoplastic Agents, Protein degradation, Biology, Bioinformatics, Article, Malignant transformation, Mice, 03 medical and health sciences, Cell Line, Tumor, Neoplasms, Heat shock protein, Drug Discovery, Animals, Humans, HSP70 Heat-Shock Proteins, HSP90 Heat-Shock Proteins, Multidisciplinary, Drug discovery, Hsp90, Cell biology, Crosstalk (biology), 030104 developmental biology, Organ Specificity, Multiprotein Complexes, biology.protein, Female, Molecular Chaperones

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7fc19bcda672d815742893f546cac7bTest
https://doi.org/10.1038/nature19807Test

المؤلفون: Gianna Ballon, Michael Stürzl, Vinay Murtadak, Stefan Tenzer, Stefan Wirtz, Yinling Hu, Barbara Ruder, Ute Distler, Ethel Cesarman, Mousumi Mahapatro, Markus F. Neurath, Florian R. Greten, Claudia Günther, Christoph Becker

المصدر: Mucosal Immunol

مصطلحات موضوعية: 0301 basic medicine, Necrosis, Transgene, Immunology, Inflammation, Mice, Transgenic, Biology, digestive system, Article, 03 medical and health sciences, Mice, Viral Proteins, medicine, Immunology and Allergy, Animals, Homeostasis, Humans, Tissue homeostasis, Cells, Cultured, Regulation of gene expression, Mice, Knockout, NF-kappa B, Herpesviridae Infections, Inflammatory Bowel Diseases, Epithelium, Cell biology, I-kappa B Kinase, Intestines, 030104 developmental biology, medicine.anatomical_structure, Enterocytes, Gene Expression Regulation, Flip, Paneth cell, Herpesvirus 8, Human, medicine.symptom

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb2ada8fb66ca2a247482da13a682aa5Test
https://europepmc.org/articles/PMC8063487Test/

المؤلفون: Patrick C. Rämer, Mário Henrique M. Barros, Thomas F. Schulz, Michael Spohn, Adam Grundhoff, Adeola Fowotade, Vanessa Landtwing, Robert E. White, Gerald Niedobitek, Ana Raykova, Jaap M. Middeldorp, Martin J. Allday, Riccarda Capaul, Jin-Man Kim, Christine T. Styles, Anita Murer, Alexandra Papoudou-Bai, Isaak Quast, Nicole Caduff, David J. Blackbourn, Donal McHugh, Henri Jacques Delecluse, Christian Münz, Ethel Cesarman, Yong Moon Lee, Andrea Zbinden

المساهمون: CCA - Cancer biology and immunology, AII - Infectious diseases, Pathology, University of Zurich, Münz, Christian

المصدر: 73.e7
Cell host & microbe, 22(1), 61-73.e7. Cell Press
McHugh, D, Caduff, N, Barros, M H M, Rämer, P C, Raykova, A, Murer, A, Landtwing, V, Quast, I, Styles, C T, Spohn, M, Fowotade, A, Delecluse, H-J, Papoudou-Bai, A, Lee, Y-M, Kim, J-M, Middeldorp, J, Schulz, T F, Cesarman, E, Zbinden, A, Capaul, R, White, R E, Allday, M J, Niedobitek, G, Blackbourn, D J, Grundhoff, A & Münz, C 2017, ' Persistent KSHV Infection Increases EBV-Associated Tumor Formation In Vivo via Enhanced EBV Lytic Gene Expression ', Cell host & microbe, vol. 22, no. 1, pp. 61-73.e7 . https://doi.org/10.1016/j.chom.2017.06.009Test

مصطلحات موضوعية: 0301 basic medicine, 10028 Institute of Medical Virology, Epstein-Barr Virus Infections, Herpesvirus 4, Human, Genes, Viral, viruses, 2405 Parasitology, PROTEIN, medicine.disease_cause, 10263 Institute of Experimental Immunology, Virus Replication, Mice, 0302 clinical medicine, 1108 Medical Microbiology, hemic and lymphatic diseases, Neoplasms, EPSTEIN-BARR-VIRUS, B-Lymphocytes, Coinfection, 2404 Microbiology, virus diseases, High-Throughput Nucleotide Sequencing, Herpesviridae Infections, 3. Good health, LYMPHOPROLIFERATIVE DISEASE, Survival Rate, Lytic cycle, 030220 oncology & carcinogenesis, B-CELLS, Herpesvirus 8, Human, Cytokines, Primary effusion lymphoma, Life Sciences & Biomedicine, 0605 Microbiology, Gene Expression Regulation, Viral, humanized mouse model, lytic EBV replication, Immunology, Lymphoproliferative disorders, 610 Medicine & health, CELL-LINES, KSHV, Biology, Kaposi sarcoma-associated herpesvirus, Microbiology, Virus, 03 medical and health sciences, HODGKIN-LYMPHOMA, EBV, Virology, Cell Line, Tumor, Lymphoma, Primary Effusion, medicine, Epstein-Barr virus, Animals, Humans, Epstein–Barr virus infection, PRIMARY EFFUSION LYMPHOMA, BURKITTS-LYMPHOMA, Science & Technology, biochemical phenomena, metabolism, and nutrition, virus-associated lymphoma, medicine.disease, Epstein–Barr virus, DNA-SEQUENCES, B cell lymphoma, Disease Models, Animal, 030104 developmental biology, Viral replication, DNA, Viral, 2406 Virology, LATENT, 570 Life sciences, biology, Parasitology, Carcinogenesis, Spleen

وصف الملف: text

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::294141d37f249da876c755ff877298bdTest
http://hdl.handle.net/10044/1/51663Test

المؤلفون: Ethel Cesarman, Lisa Giulino-Roth, Tanner Dalton, Amy Chadburn, Tony Taldone, Andrew L. Kung, Jennifer Totonchy, Gabriela Chiosis, Allison R. Rainey, Matthew J. Barth, Jouliana Sadek, Filemon S. Dela Cruz, Hediye Erdjument-Bromage, Alexander Bolaender, Anna Rodina, Herman van Besien

المصدر: Molecular cancer therapeutics. 16(9)

مصطلحات موضوعية: 0301 basic medicine, Male, Proteomics, Cancer Research, Cell Survival, Gene Expression, Antineoplastic Agents, Apoptosis, Biology, Article, Hsp90 inhibitor, 03 medical and health sciences, Mice, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, In vivo, Cell Line, Tumor, medicine, Animals, Humans, HSP90 Heat-Shock Proteins, Protein kinase B, PI3K/AKT/mTOR pathway, Cell Proliferation, TOR Serine-Threonine Kinases, Drug Synergism, Cell Cycle Checkpoints, medicine.disease, Molecular biology, Hsp90, Burkitt Lymphoma, In vitro, Lymphoma, Tumor Burden, 030104 developmental biology, Oncology, Cell culture, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Proto-Oncogene Proteins c-akt, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af45774cd96c990e888ce759b984e127Test
https://pubmed.ncbi.nlm.nih.gov/28619753Test