المؤلفون: Chengliang Wang, Puja Kumari, Chuan Li, Gabriel A. Rabinovich, Margaret M. Fettis, Sachin D. Deshmukh, Arun Wanchoo, Anthony T. Vella, Shivalee Duduskar, Gregory A. Hudalla, Christoph Sponholz, Beiyan Zhou, Michael Bauer, Ashley J. Russo, Renjie Liu, Vijay A. K. Rathinam, Santiago P. Méndez-Huergo, Jianbin Ruan, Sivapriya Kailasan Vanaja, Juan M. Pérez Sáez, Karthik Chandiran, Swathy O. Vasudevan, Antoine Ménoret

المصدر: Nat Immunol

مصطلحات موضوعية: Lipopolysaccharides, Male, 0301 basic medicine, Galectin 1, Lipopolysaccharide, Mice, chemistry.chemical_compound, 0302 clinical medicine, Alarmins, Immunology and Allergy, Caspase, Aged, 80 and over, Mice, Knockout, biology, Intracellular Signaling Peptides and Proteins, Pyroptosis, Middle Aged, Up-Regulation, Cell biology, Necroptosis, Female, Inflammation Mediators, medicine.symptom, Signal transduction, Intracellular, Signal Transduction, Adult, animal structures, Immunology, Inflammation, PTPRC, Article, 03 medical and health sciences, Sepsis, otorhinolaryngologic diseases, medicine, Animals, Humans, Aged, Macrophages, Phosphate-Binding Proteins, Endotoxemia, Mice, Inbred C57BL, Disease Models, Animal, stomatognathic diseases, RAW 264.7 Cells, 030104 developmental biology, chemistry, Case-Control Studies, biology.protein, Leukocyte Common Antigens, HeLa Cells, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcd368de112bdf46f79b07a7aa7e0a0dTest
https://doi.org/10.1038/s41590-020-00844-7Test

المؤلفون: Xiaojuan Yu, Youzhi Xu, Wenjie Lu, Qianqian Sun, Wentong Chen, Jie Jiang, Hu Xu, Ning Liu, Hongquan Wei

المصدر: The FASEB Journal. 34:13474-13493

مصطلحات موضوعية: Adult, Male, STAT3 Transcription Factor, 0301 basic medicine, medicine.medical_specialty, Hyperuricemia, Biochemistry, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Downregulation and upregulation, In vivo, Internal medicine, Phosphatidylcholine, Lipidomics, Genetics, medicine, Animals, Humans, STAT3, Molecular Biology, Triglycerides, biology, 1-Acylglycerophosphocholine O-Acyltransferase, nutritional and metabolic diseases, Hep G2 Cells, Middle Aged, medicine.disease, In vitro, Uric Acid, Lipoproteins, LDL, Mice, Inbred C57BL, Cholesterol, 030104 developmental biology, Endocrinology, Liver, chemistry, Case-Control Studies, Gene Knockdown Techniques, biology.protein, Uric acid, Female, lipids (amino acids, peptides, and proteins), Sterol Regulatory Element Binding Protein 1, 030217 neurology & neurosurgery, Biotechnology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f171057dd1544584c4a125b5cd1aed55Test
https://doi.org/10.1096/fj.202000950rTest

المؤلفون: Yang Zhao, Qi Sun, Dan Weng, Junhao Liu, Yan Gao, Xi Xu, Shiming Wang, Jianfa Zhang, Xiao Yang, Wenhao Ge, Yunxia Yang

المصدر: Diabetologia. 62:2106-2117

مصطلحات موضوعية: Male, 0301 basic medicine, Magnetic Resonance Spectroscopy, Endocrinology, Diabetes and Metabolism, ATPase, Metabolite, Type 2 diabetes, Mice, chemistry.chemical_compound, Adenosine Triphosphate, 0302 clinical medicine, Adenine nucleotide, Homeostasis, Protein Tyrosine Phosphatase, Non-Receptor Type 1, biology, Nucleotides, Chemistry, Hydrogen-Ion Concentration, Middle Aged, Metformin, medicine.anatomical_structure, Liver, Hepatocyte, Female, medicine.drug, Adult, medicine.medical_specialty, Intracellular pH, 030209 endocrinology & metabolism, Diabetes Mellitus, Experimental, 03 medical and health sciences, Internal medicine, Internal Medicine, medicine, Animals, Humans, Adenine, Cell Membrane, medicine.disease, Mice, Inbred C57BL, Disease Models, Animal, Kinetics, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, Case-Control Studies, Hyperglycemia, Hepatocytes, biology.protein, Insulin Resistance

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5dc6b30d187dbefb8c8ad54a81b9d2dTest
https://doi.org/10.1007/s00125-019-04971Test-1

المؤلفون: Anne McGowan, Rachel Byrne, Khalid Mohamed Saeed Ahmed, Mohamad O. Ahmed, James Gibney, Mark Sherlock, Isolda Frizelle, Ricardo Segurado, Kevin Moore, Fiona C. McGillicuddy, Weili Guo, Gerard Boran, Anjuli Gunness, Agnieszka Pazderska

المصدر: Diabetologia. 64(3)

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, Cross-sectional study, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, HDL Particle Size, Mean difference, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Internal medicine, Internal Medicine, medicine, Animals, Humans, HDL particle, Particle Size, Type 1 diabetes, Mice, Inbred BALB C, Cholesterol, business.industry, Macrophages, Increased hdl, Cholesterol, HDL, Middle Aged, medicine.disease, Atherosclerosis, 030104 developmental biology, Endocrinology, Cross-Sectional Studies, Diabetes Mellitus, Type 1, chemistry, Case-Control Studies, cardiovascular system, lipids (amino acids, peptides, and proteins), Female, Efflux, business, Biomarkers, ATP Binding Cassette Transporter 1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67696b85c3c732726259a7f2c6a3eba3Test
https://pubmed.ncbi.nlm.nih.gov/33169205Test

المؤلفون: Marianna D’Anna, Benedetta Maria Bonora, Lisa Menegazzo, Mattia Albiero, Angelo Avogaro, Roberta Cappellari, Gian Paolo Fadini

المصدر: Diabetologia. 63(9)

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, Angiogenesis, Neutrophils, Endocrinology, Diabetes and Metabolism, Integrin alpha4, Neovascularization, Physiologic, 030209 endocrinology & metabolism, CD49d, Diabetes Mellitus, Experimental, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Antigen, Diabetes mellitus, Internal medicine, Internal Medicine, Medicine, Animals, Humans, Dapagliflozin, Aged, Type 1 diabetes, business.industry, Endothelial Cells, Middle Aged, medicine.disease, In vitro, Endothelial stem cell, Eosinophils, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 1, nervous system, chemistry, Diabetes Mellitus, Type 2, Case-Control Studies, Female, business, Granulocytes

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c48cf0be8eab338ed2ba9c4b08696d66Test
https://pubmed.ncbi.nlm.nih.gov/32306097Test

المؤلفون: Hong Yang, Baoxue Ge, Yanghaoyu Chen, Jianxia Chen, Yan Jiang, Ling Hong

المصدر: International immunopharmacology. 91

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Tuberculosis, Mice, 129 Strain, endocrine system diseases, Immunology, Regulator, Apoptosis, Resveratrol, Biology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Sirtuin 1, medicine, Immunology and Allergy, Animals, Humans, Cells, Cultured, bcl-2-Associated X Protein, Pharmacology, Mice, Knockout, Messenger RNA, Activator (genetics), Macrophages, food and beverages, Mycobacterium tuberculosis, medicine.disease, biology.organism_classification, Enzyme Activation, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Case-Control Studies, Host-Pathogen Interactions, Cancer research, Female, Mouse Macrophage, hormones, hormone substitutes, and hormone antagonists, Mycobacterium, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15abd98dd4d1d7e43d3cf7c96bf788acTest
https://pubmed.ncbi.nlm.nih.gov/33373810Test

المؤلفون: Birgit Knebel, Jorg Kotzka, Hadi Al-Hasani, Yves Van Nieuwenhove, Tina Hörbelt, David Monteiro Barbosa, Aleksandra Nikolic, Dirk Müller-Wieland, Frederique Van de Velde, Sylvia Jacob, Pia Fahlbusch, Bruno Lapauw, D. Margriet Ouwens

المصدر: International Journal of Molecular Sciences
Volume 21
Issue 11
International Journal of Molecular Sciences, Vol 21, Iss 4144, p 4144 (2020)
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
International journal of molecular sciences 21(11), 4144 (2020). doi:10.3390/ijms21114144 special issue: "Special Issue "Mechanisms of Insulin Resistance at the Crossroad of Obesity with Associated Metabolic Abnormalities and Cognitive Dysfunction" / Special Issue Editors: Prof. Dr. Melania Manco, Guest Editor; Prof. Dr. Amalia Gastaldelli, Guest Editor"

مصطلحات موضوعية: 0301 basic medicine, Male, SREBP-1c, PATHOGENESIS, LIPOTOXICITY, DISEASE, lcsh:Chemistry, chemistry.chemical_compound, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, Medicine and Health Sciences, Insulin-Like Growth Factor I, Beta oxidation, lcsh:QH301-705.5, Spectroscopy, INSULIN-RESISTANCE, Chemistry, CHOLESTEROL, Fatty liver, General Medicine, Middle Aged, fatty liver progression, Computer Science Applications, ADIPOSE-TISSUE, Lipotoxicity, OBESITY, Lipogenesis, Sterol Regulatory Element Binding Protein 1, Adult, medicine.medical_specialty, de novo, fatty liver metabolism, 030209 endocrinology & metabolism, Mice, Transgenic, SCORING, Catalysis, Article, Inorganic Chemistry, 03 medical and health sciences, Insulin resistance, LIPID-METABOLISM, Internal medicine, NAFLD, medicine, Animals, Humans, Obesity, Physical and Theoretical Chemistry, Molecular Biology, lipogenesis, Cholesterol, Organic Chemistry, Body Weight, Lipid metabolism, medicine.disease, IGF system, Mice, Inbred C57BL, Insulin-Like Growth Factor Binding Protein 2, 030104 developmental biology, Endocrinology, Insulin-Like Growth Factor Binding Protein 3, de novo lipogenesis, lcsh:Biology (General), lcsh:QD1-999, Case-Control Studies, Hepatocytes, IGFBP2, methylation, Steatohepatitis, Insulin Resistance, REDUCED EXPRESSION, Energy Metabolism, SYSTEM

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45f008bb6fa680916ff2295140c4a23bTest

المؤلفون: Akihiro Mouri, Kuniaki Saito, Toshitaka Nabeshima, Hiroyuki Kimura, Tomoya Miyauchi, Takashi Tonoike, Norio Ozaki, Eri Umemura, Yasuko Yamamoto, Hidetoshi Matsunami, Masashi Sakurai, Noriyo Kanayama, Kenichi Kurita, Masaya Hasegawa, Wataru Nagashima, Masao Takemura, Aiji Sato Boku, Mikiko Ito, Tatsuya Tokura

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports

مصطلحات موضوعية: Male, 0301 basic medicine, Kynurenine pathway, Metabolite, 3-Hydroxyanthranilic Acid, lcsh:Medicine, Kynurenic Acid, Mice, chemistry.chemical_compound, 0302 clinical medicine, Kynurenic acid, ortho-Aminobenzoates, lcsh:Science, Kynurenine, Multidisciplinary, Depression, Tryptophan, Chronic pain, Middle Aged, Healthy Volunteers, Metabolome, Biomarker (medicine), Major depressive disorder, Female, Chronic Pain, Adult, medicine.medical_specialty, Predictive markers, Article, 03 medical and health sciences, Internal medicine, medicine, Animals, Humans, Psychiatric Status Rating Scales, Depressive Disorder, Major, business.industry, lcsh:R, Case-control study, medicine.disease, Disease Models, Animal, Interleukin 1 Receptor Antagonist Protein, 030104 developmental biology, Endocrinology, chemistry, Case-Control Studies, lcsh:Q, business, Biomarkers, Stress, Psychological, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a338e9597555d6f19213b395d5e7bcaTest
https://doi.org/10.1038/s41598-020-58806-wTest

المؤلفون: Jialu Liu, Wenxia Yang, Fuyou Liu, Shumin Zhang, Xuejing Zhu, Mengru Zeng, Yuzhang Han, Ying Luo, Shikun Yang, Li Xiao, Lin Sun, Yu Liu, Hao Wu

المصدر: Clinical science (London, England : 1979). 132(22)

مصطلحات موضوعية: 0301 basic medicine, Adult, Blood Glucose, Male, medicine.medical_specialty, Inflammation, Peripheral blood mononuclear cell, Perilipin-2, Cell Line, Diabetic nephropathy, 03 medical and health sciences, chemistry.chemical_compound, Internal medicine, Acetylglucosaminidase, medicine, Animals, Humans, Diabetic Nephropathies, Creatinine, Nephritis, Tumor Necrosis Factor-alpha, Lipid metabolism, General Medicine, Transfection, Lipid Droplets, Middle Aged, medicine.disease, Lipid Metabolism, Lipids, Sterol regulatory element-binding protein, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Endocrinology, Kidney Tubules, chemistry, Diabetes Mellitus, Type 2, Case-Control Studies, Leukocytes, Mononuclear, Tumor necrosis factor alpha, Female, medicine.symptom, Inflammation Mediators, Sterol Regulatory Element Binding Protein 1, Biomarkers, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9197d5efb0094220ce9e91c6c1ea37f4Test
https://pubmed.ncbi.nlm.nih.gov/30348828Test

المؤلفون: Gurdip Daffu, Marisa Passarelli, Edna Regina Nakandakare, Ubiratan Fabres Machado, Xiaoping Shen, Adriana Machado-Lima, Maria Lúcia Corrêa-Giannella, Ann Marie Schmidt, Raquel López-Díez, R. S. Pinto, Rodrigo T. Iborra

المصدر: International Journal of Molecular Sciences
Volume 21
Issue 19
International Journal of Molecular Sciences, Vol 21, Iss 7265, p 7265 (2020)

مصطلحات موضوعية: Glycation End Products, Advanced, Male, 0301 basic medicine, endocrine system diseases, THP-1 Cells, Receptor for Advanced Glycation End Products, 030204 cardiovascular system & hematology, RAGE (receptor), lcsh:Chemistry, Mice, chemistry.chemical_compound, 0302 clinical medicine, Glycation, Null cell, RNA, Small Interfering, Receptor, lcsh:QH301-705.5, Spectroscopy, Mice, Knockout, advanced glycation end products, General Medicine, Transfection, RAGE, Computer Science Applications, NADPH Oxidase 4, diabetes mellitus, Female, lipids (amino acids, peptides, and proteins), Efflux, Adult, musculoskeletal diseases, medicine.medical_specialty, Serum Albumin, Human, Article, Catalysis, Cell Line, Inorganic Chemistry, 03 medical and health sciences, Internal medicine, medicine, Animals, Humans, Physical and Theoretical Chemistry, Molecular Biology, Triglycerides, Glycated Hemoglobin, Cholesterol, Macrophages, Cholesterol, HDL, Organic Chemistry, Albumin, NF-kappa B p50 Subunit, nutritional and metabolic diseases, cholesterol, Cholesterol, LDL, Fibroblasts, Janus Kinase 2, Mice, Inbred C57BL, Diabetes Mellitus, Type 1, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, Gene Expression Regulation, lcsh:Biology (General), lcsh:QD1-999, chemistry, Case-Control Studies, atherosclerosis

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589e04813a4b26c542aba72dead637e8Test
https://doi.org/10.3390/ijms21197265Test