نتائج البحث

1

Seipin Knockout Mice Develop Heart Failure With Preserved Ejection Fraction

المؤلفون: Cuiting Luo, Calvin W. L. Chin, Michael R. Zile, Bo Bai, Weiping Han, Wan Ting Tay, Yanyun Fu, Yu Wang, Jayantha Gunaratne, Philip Lee, Wulin Yang, Hannah Lee Foon, Kangmin Yang, Carolyn S.P. Lam, Aimin Xu

المصدر: JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 4, Iss 8, Pp 924-937 (2019)

مصطلحات موضوعية: heart failure with preserved ejection fraction, 0301 basic medicine, lcsh:Diseases of the circulatory (Cardiovascular) system, medicine.medical_specialty, animal structures, SKO, seipin knockout, HFpEF, heart failure with preserved ejection fraction, 030204 cardiovascular system & hematology, Seipin, PRECLINICAL RESEARCH, 03 medical and health sciences, 0302 clinical medicine, NET, neutrophil extracellular trap, Fibrosis, Internal medicine, Diabetes mellitus, LA, left atrial, Medicine, titin, PEVK, proline, glutamate, valine, and lysine, LV, left ventricular, Ctrl, control (mice), IQR, interquartile range, EDPVR, end-diastolic pressure–volume relationship, biology, business.industry, fibrosis, neutrophil, Neutrophil extracellular traps, medicine.disease, 3. Good health, seipin, 030104 developmental biology, lcsh:RC666-701, Knockout mouse, biology.protein, Cardiology, Phosphorylation, Titin, Cardiology and Cardiovascular Medicine, Heart failure with preserved ejection fraction, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b771bfcd7e18dbced5868c49fe66943dTest
https://doi.org/10.1016/j.jacbts.2019.07.008Test

2

Lipid droplet biogenesis: A mystery 'unmixing'?

المؤلفون: Mike F. Renne, Yoel A. Klug, Pedro Carvalho

المصدر: Seminars in Cell & Developmental Biology. 108:14-23

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e4a4baa3ddf83256d16b7893a0fcd3Test
https://doi.org/10.1016/j.semcdb.2020.03.001Test

3

New friends for seipin — Implications of seipin partner proteins in the life cycle of lipid droplets

المؤلفون: Maria Bohnert

المصدر: Seminars in Cell & Developmental Biology. 108:24-32

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::559c9eb044cffae2938b15133963066aTest
https://doi.org/10.1016/j.semcdb.2020.04.012Test

4

Seipin Deficiency Accelerates Heart Failure Due to Calcium Handling Abnormalities and Endoplasmic Reticulum Stress in Mice

المؤلفون: Huan Wang, Youyi Zhang, Xunde Xian, Xiao-Yue Wu, George Liu, Zihao Zhou, XiaoLu Shi, Xuejing Liu, Chengzhi Yang, Ling Zhang, Zijian Li, Yuhui Wang, Wei Huang

المصدر: Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Frontiers in Cardiovascular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4714897a67018ab60fd17d6efe9ab946Test

5

SEIPIN Isoforms Interact with the Membrane-Tethering Protein VAP27-1 for Lipid Droplet Formation

المؤلفون: Nicolas Esnay, Franziska K. Kretzschmar, Elizabeth McClinchie, Kent D. Chapman, Damien Seay, Yingqi Cai, John M. Dyer, Till Ischebeck, Robert T. Mullen, Satinder K. Gidda, Michael S. Greer

المصدر: Plant Cell

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::119f502dbaaf886b6c1f3e8928d23bc3Test
https://doi.org/10.1105/tpc.19.00771Test

6

miR‑187‑3p inhibitor attenuates cerebral ischemia/reperfusion injury by regulating Seipin‑mediated autophagic flux

المؤلفون: Ju Lv, Wenfeng Yu, Peng Xie, Zhi-Zhong Guan, Ling Chen, Yumei Hu, Zhenkui Ren

المصدر: International Journal of Molecular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4616481a5eb7e6abdd1f624ec04db223Test
https://doi.org/10.3892/ijmm.2020.4642Test

7

Heterozygous deletion of Seipin in islet beta cells of male mice has an impact on insulin synthesis and secretion through reduced PPARγ expression

المؤلفون: Xu Hua, Ling Chen, Ya Wang, Jian-Wei Xiong, Peng Sun, Wenfeng Yu, Jie Wu, George Liu, Wen-Yu Song, Yan Wang

المصدر: Diabetologia. 63:338-350

مصطلحات موضوعية: Male, 0301 basic medicine, endocrine system, medicine.medical_specialty, Lipodystrophy, endocrine system diseases, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, BSCL2, 030209 endocrinology & metabolism, Seipin, Rosiglitazone, Islets of Langerhans, Mice, 03 medical and health sciences, 0302 clinical medicine, Insulin resistance, Lipodystrophy, Congenital Generalized, GTP-Binding Protein gamma Subunits, Internal medicine, Internal Medicine, medicine, Animals, Insulin, Proinsulin, geography, geography.geographical_feature_category, biology, Chemistry, medicine.disease, Islet, PPAR gamma, 030104 developmental biology, Endocrinology, Adipose Tissue, biology.protein, GLUT2, Female, Insulin Resistance, Beta cell

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c455c49e7d7e1af4ebb28b0c3916650aTest
https://doi.org/10.1007/s00125-019-05038-xTest

8

A Patient with Berardinelli-Seip Syndrome, Novel AGPAT2 Splicesite Mutation and Concomitant Development of Non-diabetic Polyneuropathy

المؤلفون: Alicja Sikora, Mateusz Dawidziuk, Anna Obuchowicz, Marta Marek, Wojciech Wiszniewski, Katarzyna Ziora, James R. Lupski, Pawel Gawlinski, Tomasz Gambin, Sylwia Rzonca, Shalini N. Jhangiani, Joanna M Oswiecimska, D. Lys Guilbride

المصدر: Journal of Clinical Research in Pediatric Endocrinology. 11:319-326

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::aaed3a2e13e2ede233ed662e734657d6Test
https://doi.org/10.4274/jcrpe.galenos.2018.2018.0227Test

9

Deletion of Seipin Attenuates Vascular Function and the Anticontractile Effect of Perivascular Adipose Tissue

المؤلفون: Jiawei Liao, Jian-Zeng Dong, Liang Hu, Junhui Xing, Mingming Gao, Yangyang Liu, George Liu, Xiaowei Li, Xiaoyan Zhao, Mengyu Wang, Mengduan Liu

المصدر: Frontiers in Cardiovascular Medicine, Vol 8 (2021)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74aa86b87500868344cfcf7998f967dTest
https://www.frontiersin.org/articles/10.3389/fcvm.2021.706924/fullTest

10

Dietary fatty acids promote lipid droplet diversity through seipin enrichment in an ER subdomain

المؤلفون: Chun Wing Fung, Yiu Yiu Lee, Wen Jiun Lam, Ho Yi Mak, Kang Xie, Yifei Qiu, Guanghou Shui, Pengfei Wang, Xuesong Li, Jianan Y. Qu, Ben Zhong Tang, Pingsheng Liu, Byung-Ho Kang, Yan Hao, Zhe Cao

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Science, General Physics and Astronomy, 02 engineering and technology, Endoplasmic Reticulum, General Biochemistry, Genetics and Molecular Biology, Seipin, Article, Cell Line, 03 medical and health sciences, Lipid droplet, GTP-Binding Protein gamma Subunits, Organelle, Animals, Humans, Caenorhabditis elegans, Caenorhabditis elegans Proteins, lcsh:Science, 2. Zero hunger, chemistry.chemical_classification, Organelles, Multidisciplinary, biology, Endoplasmic reticulum, Fatty Acids, General Chemistry, Metabolism, Lipid Droplets, 021001 nanoscience & nanotechnology, biology.organism_classification, Cell biology, Metabolic pathway, Protein Transport, 030104 developmental biology, chemistry, Metabolic pathways, lcsh:Q, 0210 nano-technology, Polyunsaturated fatty acid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f01d34d8d6cc02a18ae5affbbefb03fdTest
http://link.springer.com/article/10.1038/s41467-019-10835-4Test

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