المؤلفون: Minki Kim, Muhammad Irfan, Man Hee Rhee

المصدر: Journal of Ginseng Research, Vol 44, Iss 1, Pp 24-32 (2020)
Journal of Ginseng Research

مصطلحات موضوعية: 0301 basic medicine, MKK4, mitogen-activated protein kinase kinase 4, Ginsenosides, Syk, spleen tyrosine kinase, PPD, protopanaxadiol, AA, arachidonic acid, Review, vWF, von Willebrand factor, Pharmacology, ERK, extracellular signal–regulated kinase, chemistry.chemical_compound, Ginseng, 0302 clinical medicine, MLC, myosin light chain, lcsh:Botany, Medicine, PAR, proteinase-activated receptor, TS, total saponin, AC, adenylyl cyclase, media_common, GPVI, glycoprotein VI, [Ca2+]i, intracellular calcium ion, PI3K, phosphatidylinositol 3-kinase, lcsh:QK1-989, cAMP, cyclic adenosine monophosphate, IC50, half maximal (50%) inhibitory concentration, Ginsenoside, 030220 oncology & carcinogenesis, IP3, inositol-1,4,5-triphosphate, JNK, c-Jun N-terminal kinase, Nutraceutical, Biotechnology, Drug, Korean ginseng, ATP, adenosine triphosphate, media_common.quotation_subject, CRP, collagen-related peptide, aPTT, activated partial thromboplastin time, Biochemistry, Genetics and Molecular Biology (miscellaneous), World health, 03 medical and health sciences, PT, prothrombin time, PKC, protein kinase C, Antiplatelet, TxAS, thromboxane-A synthase, Platelet activation, ASA, acetylsalicylic acid, PAF, platelet-activating factor, TxB2, thromboxane B2, business.industry, cPLA2α, cytosolic phospholipase A2α, PLA2, phospholipase A2, Synergism, TxA2, thromboxane A2, PPT, protopanaxatriol, Anti platelet, ADP, adenosine diphosphate, COX, cyclooxygenase, 030104 developmental biology, CSF, crude saponin fraction, Complementary and alternative medicine, chemistry, ROCK, Rho-associated protein kinase, Structural modification, TxR, thromboxane receptor, Akt, protein kinase B, PLCγ2, phospholipase C gamma-2, PKG, protein kinase G, SFK, Src family kinase, PKA, protein kinase A, business, VASP, vasodilator-stimulated phosphoprotein, MAPK, mitogen-activated protein kinase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77592e2f7358ae138f91eeb44c16a0d7Test
http://www.sciencedirect.com/science/article/pii/S1226845319301332Test

المؤلفون: Matthias Epple, Yana Dautova, Kevin Pappert, Alexander N. Kapustin, Martin D. Bootman, Hanneke Okkenhaug, Diane Proudfoot, Simon J. Cook, Catherine M. Shanahan

المصدر: Journal of Molecular and Cellular Cardiology
Dautova, Y, Kapustin, A, Pappert, K, Epple, M, Okkenhaug, H, Cook, S J, Shanahan, C M, Bootman, M D & Proudfoot, D 2017, ' Calcium phosphate particles stimulate interleukin-1β release from human vascular smooth muscle cells : A role for spleen tyrosine kinase and exosome release ', Journal of Molecular and Cellular Cardiology . https://doi.org/10.1016/j.yjmcc.2017.12.007Test

مصطلحات موضوعية: 0301 basic medicine, Calcium Phosphates, Male, BM, basal culture medium, Vascular smooth muscle, Inflammasomes, Interleukin-1beta, Syk, Exosomes, Muscle, Smooth, Vascular, SYK, Phosphorylation, Cells, Cultured, Caspase 1, Inflammasome, Middle Aged, CaP, calcium phosphate, Cell biology, VSMC, vascular smooth muscle cells, Caspase-1, Cytokines, LPS, lipopolysaccharide, Female, Cardiology and Cardiovascular Medicine, medicine.drug, Adult, IL-1β, interleukin-1β, ATP, adenosine triphosphate, Myocytes, Smooth Muscle, Chemie, chemistry.chemical_element, Calcium, Exosome, MSU, monosodium urate, Article, SYK, spleen tyrosine kinase, 03 medical and health sciences, Young Adult, medicine, SFM, serum-free medium, Humans, Syk Kinase, Secretion, NLRP3: nucleotide-binding domain, leucine-rich repeat/pyrin domain-containing-3, Molecular Biology, Calcium phosphate particles, Enzyme Activation, 030104 developmental biology, chemistry

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d86e001074dcd1dcf16d9ed519a5db8Test
http://europepmc.org/articles/PMC5823844Test

المؤلفون: Edina Simon, Attila Mócsai, Dániel Csete, Zoltán Jakus, Petra Aradi, Dávid Győri, Szilvia Benkő, Ahmad Alatshan, Csaba Dobó-Nagy

المصدر: Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology

مصطلحات موضوعية: 0301 basic medicine, musculoskeletal diseases, lcsh:Immunologic diseases. Allergy, VAV1, mice, Immunology, Cre recombinase, Syk, Mice, Transgenic, chemical and pharmacologic phenomena, Biology, Bone resorption, Bone and Bones, Bone remodeling, 03 medical and health sciences, 0302 clinical medicine, Osteoclast, hemic and lymphatic diseases, medicine, Animals, Syk Kinase, Immunology and Allergy, Bone Resorption, Original Research, SYK (spleen tyrosine kinase), tyrosine kinase, hemic and immune systems, Organ Size, Hematopoietic Stem Cells, Cell biology, enzymes and coenzymes (carbohydrates), Haematopoiesis, in vivo, 030104 developmental biology, medicine.anatomical_structure, osteoclasts, Cre-Lox, biological phenomena, cell phenomena, and immunity, lcsh:RC581-607, Tyrosine kinase, Gene Deletion, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bbcbb4bcf10f859bc6960f7c058a1b5Test

المؤلفون: Mingjiang Zhu, Mingming Zhao, Shanshan Zhong, Xinli Xue, Shuyuan Guo, L. L. Li, Jianhong Lu, Yongzhen Tao, Buxing Chen, Qun Chen, Mengqing Xiao, Yujuan Zhuo, Chunzhao Yin, Huiyong Yin, Lemin Zheng, Xia Shen

المصدر: Redox Biology, Vol 21, Iss, Pp-(2019)
Redox Biology

مصطلحات موضوعية: RT, retention time, Male, TLR4, Toll like receptor 4, BEP-CE, Bicyclic endoperoxide and hydroperoxide cholesterol ester, CHD, coronary heart disease, Biochemistry, Mass Spectrometry, Mice, 0302 clinical medicine, LXRα, liver X receptor α, oxLA-CE, oxidized LA-CE, Myocardial infarction, HMGCR, HMG-CoA reductase, CBD, cerebrovascular diseases, lcsh:QH301-705.5, chol-d7, cholesterol-d7, Idol, inducible degrader of the LDL receptor, AMVN, 2, 2′-azobis(2,4-dimethylvaleronitrile), GW, GW 3965, LDLR, LDL receptor, mmLDL, minimally modified LDL, Cholesterol, WT, wide type, Cardiovascular Diseases, Knockout mouse, MI, myocardial infarction, Cholesterol Esters, lcsh:Medicine (General), ch-HpETE, cholesteryl-hydroperoxy-eicosatetraenoate, medicine.medical_specialty, NH4OAc, ammonium acetate, LA-CEOH, LA-CE hydroxide, Lipid peroxidation, CVD, cardiovascular disease, SYK, spleen tyrosine kinase, 03 medical and health sciences, PUFA, polyunsaturated fatty acid, Humans, Aged, TLC, thin layer chromatography, Macrophages, ch-HpODE, cholesteryl-hydroperoxy-octadecadienoate, Lipid Metabolism, medicine.disease, Dil-LDL, 1,1′-dioctadecyl-3,3,3′,3′-tetramethyl-indocarbocyanine perchlorate labeled LDL, 030104 developmental biology, Endocrinology, LA-CE, cholesteryl linoleate, LDL oxidation, Biomarkers, 030217 neurology & neurosurgery, MRM, multiple reaction monitoring, 0301 basic medicine, CE19:0, cholesteryl nonadecanoate, Clinical Biochemistry, ch-HODE, cholesteryl-hydroxy-octadecadienoate, Endogeny, LDL, low density lipoprotein, Pathogenesis, Cholesterol/metabolism, chemistry.chemical_compound, BSTFA+TMCS, Bis-(trimethylsilyl)-trifluoroacetamide+Trimethylchlorosilane, Cholesterol uptake, IS, internal standard, PPh3, triphenylphosphine, CEOH, CE hydroxide, Liver X Receptors, lcsh:R5-920, CEOOH, cholesterol ester hydroperoxide, Chemistry, BMDM, bone marrow-derived macrophage, Middle Aged, CVD, ch-13c,t-HpODE, cholesteryl-13(cis, trans)-hydroperoxy-octadecadienoate, ch-HETE, cholesteryl-hydroxy-eicosatetraenoate, Metabolome, LXR, Female, lipids (amino acids, peptides, and proteins), oxCE, oxidized CE, Research Paper, IPA, isopropanol, AA-CE, cholesteryl arachidonate, Cholesterol ester hydroperoxides, CE, cholesterol ester, T09, T0901317, ROS, reactive oxygen species, Internal medicine, BHT, butylated hydroxytoluene, medicine, Animals, oxLDL, oxidized LDL, Organic Chemistry, IP, intraperitoneal injection, Disease Models, Animal, LDLR, Receptors, LDL, lcsh:Biology (General), NaOMe, sodium methoxide, Lipidomics, LDL receptor, Hepatocytes, Chromatography, Liquid, Lipoprotein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1989f770bc806092616979f001bbee92Test
http://www.sciencedirect.com/science/article/pii/S2213231718310851Test

المؤلفون: Hanke L. Matlung, Katka Szilagyi, Taco W. Kuijpers, Timo K. van den Berg, Dieke J van Rees

المساهمون: Amsterdam institute for Infection and Immunity, Molecular cell biology and Immunology, AII - Cancer immunology, CCA - Cancer immunology

المصدر: van Rees, D J, Szilagyi, K, Kuijpers, T W, Matlung, H L & van den Berg, T K 2016, ' Immunoreceptors on neutrophils ', Seminars in immunology, vol. 28, no. 2, pp. 94-108 . https://doi.org/10.1016/j.smim.2016.02.004Test
Seminars in Immunology
Seminars in immunology, 28(2), 94-108. Academic Press Inc.

مصطلحات موضوعية: 0301 basic medicine, Syk, spleen tyrosine kinase, Neutrophils, Syk, GBS, group B Streptococci, MPO, myeloperoxidase, RA, rheumatoid arthritis, Plasma protein binding, IVIg, intravenous immunoglobulins, GPI, glycophosphatidylinositol, Neutrophil Activation, SLE, systemic lupus erythematosus, PTPN6, tyrosine-protein phosphatase non-receptor type 6, 0302 clinical medicine, SLP-76, SH2 domain containing leukocyte protein of 76 kDa, ERK, extracellular signal-regulated kinase, PIP2, phosphatidylinositol (4,5)-bisphosphate, ITAM, SHP, Immunology and Allergy, Receptors, Immunologic, SHP, SH2-domain containing phosphatase, SOCS, suppressor of cytokine signaling proteins, Antibody-dependent cell-mediated cytotoxicity, SHIP, SH2-domain containing inositol phosphatase, Effector, DAP12, DNAX activation protein of 12 kDa, hemic and immune systems, PS, phosphatidylserine, ANCAs, anti-neutrophil autoantibodies, Cell biology, IgSF, Immunoglobulin superfamily, Biochemistry, PH domain, pleckstrin homology domain, PI(3,4)P2, phosphatidylinositol (3,4)-bisphosphate, Disease Susceptibility, Signal transduction, SNP, single-nucleotide polymorphism, IP3, inositol triphosphate, SHIP, SH2, Src homology 2, PMN, polymorphonuclear leukocytes, Protein Binding, Signal Transduction, NETs, neutrophil extracellular traps, Immunology, chemical and pharmacologic phenomena, Biology, Btk, Bruton's tyrosine kinase, PE, phosphatidylethanolamine, Article, GEF, guanine nucleotide exchange factor, 03 medical and health sciences, Immune system, PLC, phospholipase C, ROS, reactive oxygen species, ORF, open reading frame, PKC, protein kinase C, Animals, Humans, ITAM, immunoreceptor tyrosine-based activating motif, MLCK, myosin light-chain kinase, Immunoreceptors, PI3K/AKT/mTOR pathway, GPCR, G protein-coupled receptor, G protein-coupled receptor, DAG, diacyl-glycerol, ADCC, antibody-dependent cellular cytotoxicity, MRP8, myeloid-related protein 8, ITIM, immunoreceptor tyrosine-based inhibitory motif, NADPH, nicotinamide adenine dinucleotide phosphate, ITIM, Immunity, Innate, IRAK, interleukin-1 receptor-associated kinase, Grb2, growth factor receptor-bound protein 2, 030104 developmental biology, Gene Expression Regulation, PI3K, phosphatidylinositol-4,5-bisphosphate 3-kinase, fMLP, N-Formylmethionine-leucyl-phenylalanine, MAPK, mitogen-activated protein kinase, Biomarkers, 030215 immunology, PIP3, phosphatidylinositol (3,4,5)-trisphosphate

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498f6a028ffa967d55b1919325120864Test
https://research.vumc.nl/en/publications/08d2d945-819c-4fe2-8ba4-abf1bff0994eTest